Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0677930 (primary tumor)
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Human Gene/Protein
GTP binding protein 4 10.6
inhibin, beta B 10.6
abhydrolase domain containing 14B 10.6
NPCEDRG 10.6
LOC642587 10.6
PCDH9 protein 10.6
MGST1 protein 10.6
C6orf102 10.6
C6orf64 10.6
PAX interacting protein 1 10.6
AlphaTFEB 10.6
PDGFB protein 10.6
glioma amplified sequence 64 10.6
chromosome 15 open reading frame 42 10.6
ZDHHC11B 10.6
SRGAP2 protein 9.6
TRY1 9.6
FIBCD1 protein 9.6
AARSD1 9.6
sideroflexin 3 9.6
FLJ10781 9.6
CNIH4 9.6
transmembrane protein 35 9.6
G1/S-specific cyclin E2 9.6
chloride channel accessory 4 9.6
TIMM17A 9.6
CYTH3 9.6
MGC48628 9.6
C7orf4 9.6
MRCL 9.6
dishevelled 3 9.6
MFAP3L 9.0
EMILIN3 9.0
GEMIN5 9.0
GON4L 9.0
ZSWIM7 9.0
ZNF3 9.0
SCC-112 9.0
FAM179A 9.0
FAM107B 9.0
sclerostin domain containing 1 9.0
C19orf2 9.0
NLVCF 9.0
CACHD1 9.0
ATP-binding cassette subfamily B member 5 8.6
ZNF721 8.6
CTAGE1 8.6
FAM120AOS 8.6
CRIPAK 8.6
ZNF677 8.6
p87(PIKAP) 8.6
COTE1 8.6
renal cell carcinoma 4 8.6
PPP1R13B 8.6
SMYD2 protein 8.6
EMLP 8.6
BRP44L 8.6
S100D 8.6
NICE-3 8.6
Kinesin family member 2C 8.6
p42.3 8.5
K-Cl cotransporter 3 8.3
v-Ha-ras Harvey rat sarcoma viral oncogene homolog 8.3
SLIT2 protein 8.3
TMED3 8.3
Actin-like protein 8.3
PAI1 mRNA 8.3
KRT33B 8.3
MXD4 8.3
ANGPT4 8.3
ACVR1C 8.3
EIF2C3 8.3
DUB-3 8.3
breast cancer metastasis suppressor 1 8.1
GTPBP4 8.0
B4GALT2 8.0
GIMAP7 8.0
ERGIC3 8.0
GSG2 8.0
myeloid ecotropic integration site 1 8.0
more...
Disease
Other thyroid disorders 10.6
Metastatic liver carcinoma 10.6
Labium minus 10.6
Peritoneal adenocarcinoma 10.6
Local tumor spread 10.6
Adnexal tumor 10.6
Adenocarcinoma with neuroendocrine differentiation 10.6
Intrapelvic lymph nodes 10.6
Malignant esophageal stricture 10.6
primary tumor 10.6
Primary Peritoneal Carcinoma 10.6
Paraspinal neuroblastoma 10.6
Metastatic renal carcinoma 10.0
Bowen's disease, verrucous 9.6
pediatric liposarcoma 9.6
Peritoneal carcinoma 9.6
Sympathetic paraganglioma 9.6
regional neuroblastoma 9.6
childhood infratentorial ependymoma 9.6
Sertoli cell carcinoma 9.6
Malignant ameloblastoma 9.6
localized skin tumor 9.6
Mucinous breast cancer 9.6
stage IV hypopharyngeal cancer 9.6
Pilocytic Astrocytoma 9.6
Oligoastrocytoma 9.0
Supratentorial PNET 9.0
Inflammatory carcinoma 9.0
metastatic vulvar cancer 9.0
Oligoastrocytoma 9.0
Terminal Cancer 9.0
recurrent vaginal cancer 9.0
recurrent Wilms tumor 8.8
Disseminated carcinoma 8.6
Pancreatic duct dilatation 8.6
Paraneoplastic neuropathy 8.6
Gastric Adenocarcinoma 8.6
Primary bronchial cancer 8.6
Metaplastic squamous cell carcinoma 8.6
metastatic laryngeal cancer 8.6
small cell lung cancer stage 8.6
Serous surface papillary carcinoma 8.6
TGCT1 8.6
Secondary carcinoma 8.6
Optic nerve sheath meningioma 8.6
Penile Cancer 8.5
Malignant granular cell tumor 8.3
Myofibrosarcoma 8.3
glossoplegia 8.3
Round cell liposarcoma 8.3
Estrogenic effect 8.3
stage I rectal cancer 8.3
Mesenchymal Tumor 8.3
Neuroepitheliomas 8.3
Single tumor 8.3
unknown primary cancer 8.2
stage IV colorectal cancer 8.1
Pleural metastases 8.0
Dedifferentiated chordoma 8.0
Combined small cell carcinoma 8.0
Dukes A colon cancer 8.0
benign giant cell tumor of bone 8.0
Glomus jugulare tumor 8.0
Smooth muscle tumor 8.0
stage IV pancreatic cancer 8.0
Axillary metastases 7.9
relapsed childhood AML 7.8
lower urinary tract cancer 7.8
stage I colorectal cancer 7.8
Metastatic basal cell carcinoma 7.8
Lupus-like syndrome 7.8
Pleural fibroma 7.8
Breast metastases 7.7
Endobronchial metastases 7.6
stage II NSCLC 7.6
type C thymoma 7.6
adult rhabdomyosarcoma 7.6
digestive neoplasm 7.6
rectal cancer stage 7.6
Schneiderian carcinoma 7.6
more...
Symptom
olfactory anesthesia 9.6
Sister Mary Joseph's nodule 8.1
jaundice of the skin 6.6
epigastric distress 6.0
lump in the neck 5.9
McBurney's point 5.8
Pain and tenderness 5.5
diminished hearing 5.5
penile lesion 5.4
finger pain 5.4
Overlying 5.2
Foot pain 5.1
Severe diarrhea 4.8
abdominal fullness 4.7
General symptoms 4.7
anal pain 4.7
menometrorrhagia 4.3
Spotting 4.2
peau d'orange 4.1
dyschezia 3.8
bone pain 3.7
neck stiffness 3.7
epigastric pain 3.7
Signs and Symptoms 3.5
lassitude 3.5
flank pain 3.3
right upper quadrant pain 3.2
frequent urination 3.2
testicular pain 3.2
jaw pain 3.1
chyluria 3.0
giddiness 3.0
giddiness 3.0
Cushingoid 2.9
ENT 2.8
inanition 2.8
leg edema 2.8
Cushingoid 2.8
forgetfulness 2.8
ACHE 2.7
tenesmus 2.7
physical symptom 2.7
stomach pain 2.7
otalgia 2.7
nipple discharge 2.6
anorexia 2.6
dysuria 2.5
abdominal pain 2.5
nipple discharge 2.5
urinary frequency 2.5
asthenia 2.4
urethral discharge 2.4
cachexia 2.4
cancer pain 2.4
right lower quadrant pain 2.4
nausea and vomiting 2.3
No adverse effect 2.3
hemoptysis 2.3
hoarseness 2.3
blurred vision 2.2
prostration 2.1
nausea 2.1
loss of taste 2.1
irregular bleeding 2.0
Scratch 2.0
dyspnea 2.0
intestinal bleeding 2.0
renal colic 2.0
exertional dyspnea 1.9
masculinization 1.9
abdominal discomfort 1.9
shortness of breath 1.9
hepatomegaly 1.8
clubbing 1.8
hip pain 1.8
paresthesia 1.8
Spots 1.8
flushing 1.8
orthopnea 1.8
numbness 1.7
more...
Drug
CEA-Scan 8.3
Trocade 8.0
Iotasul 7.5
OctreoScan 6.9
Isosulfan blue 6.8
ProstaScint 6.6
Tobi 6.2
Ferumoxtran-10 5.8
MTC 5.6
Leucovorin 5.2
Sandostatin LAR 5.2
Leukine 5.2
Amlexanox 5.2
Batimastat 5.1
Batimastat 5.1
Temodal 5.1
Sunitinib malate 5.0
CDX 4.9
Nexavar 4.9
Epidoxorubicin 4.8
Tykerb 4.8
Vindesine 4.8
Vindesine 4.7
Adriamycin 4.6
Lipiodol 4.6
CPT-11 4.6
CDX 4.5
Levamisol 4.5
KAN 4.5
Fulvestrant 4.5
Cilengitide 4.5
Marimastat 4.5
Trabectedin 4.4
Tetrofosmin 4.4
Sandostatin 4.4
Sandostatin 4.4
Xeloda 4.3
uPA 4.3
Propentofylline 4.3
CTC 4.3
Panitumumab 4.3
Swainsonine 4.2
Dexrazoxane 4.2
Zoladex 4.2
Herceptin 4.2
Docetaxel 4.2
Navelbine 4.1
Pirarubicin 4.1
PTC 4.1
Phenprocoumon 4.1
Maraviroc 4.1
Paraffin 4.1
Casodex 4.0
Ferumoxytol 4.0
Bevacizumab 4.0
CTC 4.0
Zoledronic acid 4.0
Gleevec 3.9
Mitomycin-C 3.9
Sodium acetate 3.9
Taxotere 3.9
Zoladex 3.9
Diamminedichloroplatinum 3.9
VCR 3.9
Vinorelbine 3.9
Intron A 3.8
Ulinastatin 3.8
HCG 3.8
Vorinostat 3.7
Estracyt 3.7
Imatinib 3.7
Estracyt 3.6
Intron A 3.6
Axitinib 3.6
Pertuzumab 3.6
Intron A 3.6
Hyperforin 3.6
Vandetanib 3.5
Everolimus 3.5
RBT 3.5
more...
Enzyme
3-KSR 9.0
L-phenylalanine oxidase 6.7
L-lysine alpha-oxidase 6.2
MGAT 5.9
L-asparagine synthetase 5.8
inositol polyphosphate 4-phosphatase 5.5
FTR 4.8
alpha-methylacyl-CoA racemase 4.8
LGT 4.8
prostate-specific membrane antigen 4.7
aspartoacylase 4.6
ALDH 4.5
nicotinic acid phosphoribosyltransferase 4.4
hepsin 4.4
hepsin 4.4
CGT 4.4
methylthioadenosine phosphorylase 4.3
matrix metalloproteinase 14 4.2
chondroitin ABC lyase 4.1
CLK1 4.1
STK11 4.1
cancer procoagulant 4.1
legumain 4.0
AFR 4.0
phosphatidylinositol-4,5-bisphosphate 3-kinase 4.0
matrix metalloproteinase 2 4.0
dihydropyrimidine dehydrogenase 4.0
dihydropyrimidine dehydrogenase 3.9
methylenetetrahydrofolate dehydrogenase 3.9
SST 3.9
lysyl oxidase 3.8
sterol carrier protein 3.8
matrix metalloproteinase 9 3.8
DSR 3.7
LTC4 synthase 3.7
lysyl hydroxylase 3.7
glycoprotease 3.7
nicotinamide mononucleotide adenylyltransferase 3.6
mannosidase II 3.6
T-protein 3.6
stromelysin-3 3.6
MDP 3.6
ERK 3.5
urokinase-type plasminogen activator 3.5
methylenetetrahydrofolate dehydrogenase 3.4
N-acetylglucosaminyltransferase V 3.3
phosphoglycerate dehydrogenase 3.3
methioninase 3.3
prostate-specific antigen 3.3
MAT 3.2
CPM 3.2
indoleamine 2,3-dioxygenase 3.1
3alpha-hydroxysteroid dehydrogenase 3.1
thymidylate synthase 3.1
MAT 3.0
MMP 3.0
DCF 3.0
N-acetylglucosaminyltransferase I 3.0
PMT 3.0
MTD 3.0
acyl carrier protein synthase 2.9
thymidine phosphorylase 2.9
uridine kinase 2.9
uridyltransferase 2.9
TSP-1 2.9
GM3 synthase 2.9
firefly luciferase 2.9
aminopeptidase B 2.9
proprotein convertase 2.8
PRT 2.8
BMA 2.8
endo-N 2.7
cytidine deaminase 2.7
astacin 2.7
cytosine deaminase 2.7
granzyme B 2.6
TMT 2.6
cathepsin D 2.5
HK2 2.5
enolase 2.5
more...
Compound
Tetrahydrocortisol 8.5
Pseurotin A 8.0
Bruceantin 7.8
4-methyl-1,3-thiazole 7.5
Lycurim 7.3
ethyl 3,4-dihydroxybenzoate 6.8
Illudin S 6.5
Dequalinium chloride 6.4
Borrelidin 6.2
Rubratoxin B 6.2
SLEX 6.2
Borrelidin 6.2
Patent blue 6.0
TNN 6.0
Rocaglamide 5.9
ENNG 5.9
Pyran 5.8
TNM 5.8
Droloxifene 5.8
Lentinan 5.7
THP-ADM 5.7
MTC 5.6
Carboquone 5.6
Tiazofurin 5.5
Nedaplatin 5.5
FANFT 5.3
Carboquone 5.3
Mafosfamide 5.3
Carboquone 5.3
Carboquone 5.3
Carboquone 5.3
Concanamycin A 5.2
Triacetin 5.2
A 99 5.2
Nitrosoguanidine 5.2
Nitrosoguanidine 5.2
Leucovorin 5.2
VMA 5.1
PPBP 5.1
delta8-THC 5.1
MTU 5.1
GMDP 5.0
PMEG 4.9
IDC 4.9
Pristimerin 4.9
Pristimerin 4.9
Pristimerin 4.9
Pristimerin 4.9
SHT 4.9
5-FU 4.9
CCNU 4.9
NEU 4.9
DPBS 4.9
Pimonidazole 4.8
Pimonidazole 4.8
VCC 4.8
DFS 4.7
MGBG 4.7
MGBG 4.7
BEP 4.7
4-Methylumbelliferone 4.6
CPT-11 4.6
Anastrozole 4.6
o,p'-DDD 4.6
Vidarabine 4.5
Tegafur 4.4
Cucurbitacin B 4.4
MeCCNU 4.4
Ifosfamide 4.4
TME 4.4
Tegafur 4.3
EOC 4.3
Vimentin 4.3
BPQ 4.2
Vincristine 4.2
ethyl benzoate 4.2
Azoxymethane 4.2
Docetaxel 4.2
SCC 4.2
Thiotepa 4.1
more...