Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0677930 (primary tumor)
20,210 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein Sep 1191 nodal 801 Mol 715 p53 584 osteosarcoma 341 estrogen receptor 298 FDG 294 TNM 284 epidermal growth factor receptor 282 HER2 267 MRI 259 cytokine 208 She 204 vascular endothelial growth factor 199 E-cadherin 196 vimentin 192 collagen 180 CD8 179 progesterone receptor 176 cytokeratin 171 Ki-67 167 EGFR 165 carcinoembryonic antigen 162 rhabdomyosarcoma 157 KRAS 150 cage 145 BRAF 144 tyrosine kinase 141 interferon 136 CD44 129 CEA 119 VEGF 109 somatostatin 108 AKT 102 colon carcinoma 102 lymphoid 101 p16 98 hormone receptor 95 CXCR4 93 catenin 91 CD4 89 matrix metalloproteinase 88 chemokine 87 fibronectin 84 PI3K 84 PIK3CA 81 IFN 80 erbB-2 78 mTOR 77 MMP-9 76 Bcl-2 76 mucin 74 PTEN 73 CD34 72 urokinase-type plasminogen activator 72 CXCL12 70 ras 69 IL-2 69 Pol 68 alpha-fetoprotein 68 PD-L1 68 neu 67 IL-6 66 CK20 65 tumor necrosis factor 65 MAPK 65 desmin 64 MMP-2 64 epidermal growth factor 63 androgen receptor 63 caspase-3 62 alkaline phosphatase 62 synaptophysin 61 PD-1 61 IFN-gamma 60 c-myc 59 p21 58 metastasis suppressor 58 neuron-specific enolase 58 reserved 57 more...

Disease primary tumor 20210 tumor 12798 cancer 9003 metastases 7239 carcinoma 2796 breast cancer 2504 melanoma 1270 adenocarcinoma 1263 tumor growth 1043 squamous cell carcinoma 959 tumor progression 935 colorectal cancer 831 lung cancer 745 liver metastases 599 lung metastases 566 prostate cancer 541 lung carcinoma 516 gastric cancer 501 renal cell carcinoma 477 sarcoma 476 tumorigenesis 439 osteosarcoma 426 hepatocellular carcinoma 371 neuroblastoma 352 non-small cell lung cancer 350 colon cancer 325 lymphoma 314 carcinogenesis 313 metastatic breast cancer 294 residual disease 278 bone metastases 247 brain metastases 235 ovarian cancer 225 pancreatic cancer 222 glioma 201 carcinoid 199 head and neck cancer 190 rectal cancer 187 rhabdomyosarcoma 180 aggressiveness 169 glioblastoma 169 esophageal cancer 165 mammary tumor 161 esophageal cancer 158 leukemia 155 lymphadenopathy 155 epithelial ovarian cancer 153 bladder cancer 142 solid tumor 142 Ewing's sarcoma 142 brain tumor 125 cutaneous melanoma 124 cervical cancer 121 Melanoma 120 metastatic melanoma 119 fibrosarcoma 117 SCID 115 thyroid cancer 114 small cell lung cancer 113 tumor angiogenesis 109 neuroendocrine tumor 106 WT1 106 carcinomatosis 99 glioblastoma multiforme 98 endometrial cancer 91 Hodgkin's disease 90 teratoma 89 bronchogenic carcinoma 89 leiomyosarcoma 87 lymphatic vessels 87 MCF 86 Osteosarcoma 83 Osteosarcoma 83 aggression 83 anemia 82 systemic disease 81 meningioma 81 metastatic renal cell carcinoma 80 adenoma 79 multiple myeloma 79 more...

Symptom pain 276 abdominal pain 114 diarrhea 94 dyspnea 70 headache 67 vomiting 67 anesthesia 64 nausea 63 anorexia 53 fatigue 52 cough 48 weakness 43 seizures 34 nausea and vomiting 31 epigastric pain 28 discomfort 28 discomfort 28 bone pain 26 back pain 25 ENT 24 chest pain 22 cachexia 19 hemoptysis 19 constipation 16 ataxia 15 splenomegaly 15 respiratory distress 14 flushing 14 flank pain 14 dizziness 13 hepatomegaly 13 Sister Mary Joseph's nodule 13 collapse 12 shortness of breath 12 paresis 12 numbness 11 paresthesia 11 cancer pain 10 hoarseness 9 analgesia 9 Ill 9 dysuria 9 syncope 9 asthenia 9 low back pain 8 exhaustion 8 hypothermia 8 exertional dyspnea 8 overweight 7 erythema 7 myoclonus 7 abdominal fullness 7 starvation 7 dysarthria 6 acidity 6 blurred vision 6 masculinization 6 regurgitation 5 neck stiffness 5 tremor 5 hemiplegia 5 colic 5 lethargy 5 pelvic pain 5 angina 5 tinnitus 4 polyuria 4 hip pain 4 otalgia 4 sore throat 4 abdominal discomfort 4 right upper quadrant pain 4 neck pain 4 anal pain 4 urinary frequency 4 chills 4 vertigo 4 myalgia 3 arthralgia 3 cyanosis 3 more...

Drug Dermatol 158 Cardiovasc 108 Adriamycin 74 IL-2 71 CSF 61 IFN-gamma 59 CTX 50 ENT 41 CPT-11 29 uPA 27 Herceptin 26 Monit 25 Paraffin 23 HCG 23 Docetaxel 20 Imatinib 20 lysine 19 PTC 19 Bevacizumab 18 MAP 18 Taxol 17 MTC 16 ADM 16 ROC 16 CTX 15 CTX 15 Gleevec 14 CTC 13 CTC 13 Lipiodol 13 ROS 12 Leaf 12 CAM 12 Leucovorin 12 MDS 11 GEO 10 Indomethacin 10 Meth 9 ABC 9 VCR 9 ADR 8 Portal 8 PTH 8 ETS 8 Sorafenib 8 Mutagen 7 CDP 7 VCR 6 Bortezomib 6 RFP 6 vitamin E 6 TAC 6 ACT 6 Etoposide 6 Gel 6 ALA 6 Cetuximab 6 Taxotere 6 Zoledronic acid 5 Erlotinib 5 CDX 5 Everolimus 5 Gelfoam 5 Fulvestrant 5 CDX 5 ascorbate 5 OctreoScan 5 Zoledronic acid 5 DNase I 4 CPM 4 Gefitinib 4 Sandostatin 4 Urokinase 4 Irinotecan 4 R1881 4 G-CSF 4 Oxaliplatin 4 NVP 4 Histamine 4 PDL 4 more...

Enzyme ERK 709 mitogen-activated protein kinase 152 focal adhesion kinase 142 luciferase 93 urokinase-type plasminogen activator 76 protein kinase 65 alkaline phosphatase 62 lactate dehydrogenase 54 reverse transcriptase 53 ACS 52 MEK 52 caspase-3 51 prostate-specific antigen 42 APC 41 collagenase 37 prostate-specific membrane antigen 30 peroxidase 29 acid phosphatase 25 matrix metalloproteinase 2 23 CD10 22 MMP 22 PARP 20 thrombin 20 proteasome 20 MDP 20 thymidylate synthase 19 matrix metalloproteinase 9 19 thymidine kinase 18 protein kinase C 17 trypsin 17 plasmin 17 tyrosinase 16 beta-galactosidase 16 cdc2 15 phosphatidylinositol 3-kinase 15 cathepsin D 15 catalase 15 topoisomerase 15 aldehyde dehydrogenase 15 aldehyde dehydrogenase 14 aldehyde dehydrogenase 14 aldehyde dehydrogenase 14 topoisomerase 14 aldehyde dehydrogenase 14 RNA polymerase 14 granzyme B 13 ALDH 13 P-glycoprotein 13 enolase 13 firefly luciferase 13 lysozyme 13 caspase-8 12 dihydropyrimidine dehydrogenase 12 transcriptase 11 RNase 11 lysyl oxidase 11 glutathione S-transferase 11 RNase 11 gamma-glutamyl transpeptidase 10 GSK 10 DCF 10 carbonic anhydrase 10 phosphoinositide 3-kinase 10 DNA methyltransferase 10 isocitrate dehydrogenase 9 isocitrate dehydrogenase 9 MAT 9 MAT 9 cathepsin B 9 AMP-activated protein kinase 9 aspartate aminotransferase 8 dihydropyrimidine dehydrogenase 8 tryptase 8 endonuclease 8 indoleamine 2,3-dioxygenase 8 NOS 8 IKK 8 ATPase 8 alanine aminotransferase 7 MMP-3 7 more...

Compound Clin 1558 Dec 1372 DNA 1124 TNM 284 MDA 215 5-FU 133 oxygen 129 glucose 118 tyrosine 98 calcium 98 Adriamycin 90 iodine 76 methionine 70 water 68 His 57 ACS 52 ACS 51 arginine 51 CTX 50 DDP 50 acetate 50 galactose 49 phosphate 47 sulfate 47 MTT 45 fluorine 42 TNF 42 serine 42 nitric oxide 41 Thyroid 40 sodium 39 PEG 39 SCC 38 Estrogen 38 MEK 38 barium 37 iron 36 BCG 36 Estrogen 35 Optimal 34 VP-16 34 formaldehyde 32 DBA 32 Vimentin 31 ATP 31 PEG 30 Methotrexate 30 cysteine 30 retinoic acid 30 CPT-11 29 lysine 29 leucine 28 DTPA 28 ACTH 27 ASA 27 Gly 27 ADR 26 Asp 26 Phe 25 DBA 25 DBA 25 hyaluronic acid 24 cobalt 24 MMC 23 Paclitaxel 23 DFS 22 CAM 22 DIC 20 ethanol 20 bromide 19 threonine 19 urea 18 PMA 18 potassium 18 Tamoxifen 17 zinc 17 folinic acid 17 Tamoxifen 17 Cardiol 17 MTX 17 more...

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