Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0677930 (
primary tumor
)
20,210
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
1191
nodal
801
Mol
715
p53
584
osteosarcoma
341
estrogen receptor
298
FDG
294
TNM
284
epidermal growth factor receptor
282
HER2
267
MRI
259
cytokine
208
She
204
vascular endothelial growth factor
199
E-cadherin
196
vimentin
192
collagen
180
CD8
179
progesterone receptor
176
cytokeratin
171
Ki-67
167
EGFR
165
carcinoembryonic antigen
162
rhabdomyosarcoma
157
KRAS
150
cage
145
BRAF
144
tyrosine kinase
141
interferon
136
CD44
129
CEA
119
VEGF
109
somatostatin
108
AKT
102
colon carcinoma
102
lymphoid
101
p16
98
hormone receptor
95
CXCR4
93
catenin
91
more...
Disease
primary tumor
20210
tumor
12798
cancer
9003
metastases
7239
carcinoma
2796
breast cancer
2504
melanoma
1270
adenocarcinoma
1263
tumor growth
1043
squamous cell carcinoma
959
tumor progression
935
colorectal cancer
831
lung cancer
745
liver metastases
599
lung metastases
566
prostate cancer
541
lung carcinoma
516
gastric cancer
501
renal cell carcinoma
477
sarcoma
476
tumorigenesis
439
osteosarcoma
426
hepatocellular carcinoma
371
neuroblastoma
352
non-small cell lung cancer
350
colon cancer
325
lymphoma
314
carcinogenesis
313
metastatic breast cancer
294
residual disease
278
bone metastases
247
brain metastases
235
ovarian cancer
225
pancreatic cancer
222
glioma
201
carcinoid
199
head and neck cancer
190
rectal cancer
187
rhabdomyosarcoma
180
glioblastoma
169
more...
Symptom
pain
276
abdominal pain
114
diarrhea
94
dyspnea
70
headache
67
vomiting
67
anesthesia
64
nausea
63
anorexia
53
fatigue
52
cough
48
weakness
43
seizures
34
nausea and vomiting
31
discomfort
28
discomfort
28
epigastric pain
28
bone pain
26
back pain
25
ENT
24
chest pain
22
hemoptysis
19
cachexia
19
constipation
16
splenomegaly
15
ataxia
15
flushing
14
respiratory distress
14
flank pain
14
hepatomegaly
13
dizziness
13
Sister Mary Joseph's nodule
13
collapse
12
shortness of breath
12
paresis
12
numbness
11
paresthesia
11
cancer pain
10
Ill
9
syncope
9
more...
Drug
Dermatol
158
Cardiovasc
108
Adriamycin
74
IL-2
71
CSF
61
IFN-gamma
59
CTX
50
ENT
41
CPT-11
29
uPA
27
Herceptin
26
Monit
25
HCG
23
Paraffin
23
Imatinib
20
Docetaxel
20
lysine
19
PTC
19
MAP
18
Bevacizumab
18
Taxol
17
MTC
16
ADM
16
ROC
16
CTX
15
CTX
15
Gleevec
14
CTC
13
CTC
13
Lipiodol
13
CAM
12
Leucovorin
12
ROS
12
Leaf
12
MDS
11
GEO
10
Indomethacin
10
VCR
9
Meth
9
ABC
9
more...
Enzyme
ERK
709
mitogen-activated protein kinase
152
focal adhesion kinase
142
luciferase
93
urokinase-type plasminogen activator
76
protein kinase
65
alkaline phosphatase
62
lactate dehydrogenase
54
reverse transcriptase
53
MEK
52
ACS
52
caspase-3
51
prostate-specific antigen
42
APC
41
collagenase
37
prostate-specific membrane antigen
30
peroxidase
29
acid phosphatase
25
matrix metalloproteinase 2
23
CD10
22
MMP
22
thrombin
20
MDP
20
PARP
20
proteasome
20
thymidylate synthase
19
matrix metalloproteinase 9
19
thymidine kinase
18
protein kinase C
17
trypsin
17
plasmin
17
beta-galactosidase
16
tyrosinase
16
cdc2
15
phosphatidylinositol 3-kinase
15
aldehyde dehydrogenase
15
cathepsin D
15
topoisomerase
15
catalase
15
aldehyde dehydrogenase
14
more...
Compound
Clin
1558
Dec
1372
DNA
1124
TNM
284
MDA
215
5-FU
133
oxygen
129
glucose
118
tyrosine
98
calcium
98
Adriamycin
90
iodine
76
methionine
70
water
68
His
57
ACS
52
arginine
51
ACS
51
CTX
50
acetate
50
DDP
50
galactose
49
sulfate
47
phosphate
47
MTT
45
fluorine
42
serine
42
TNF
42
nitric oxide
41
Thyroid
40
PEG
39
sodium
39
Estrogen
38
SCC
38
MEK
38
barium
37
BCG
36
iron
36
Estrogen
35
VP-16
34
more...