Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0677930 (primary tumor)
 20,210 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Primary T-cell lymphoma within the central nervous system is extremely rare. Imaging characteristics appear indistinguishable from the more common B-cell lymphoma. A case of such a primary tumor is discussed and the MRI and CT findings presented.
 ...
PMID:Cerebellar T-cell lymphoma: an unusual primary intracranial neoplasm. 128 44

Magnetic resonance (MR) images of 18 cases of hilar cholangiocarcinoma were evaluated to compare the effectiveness of Gd-DTPA with that of high dose contrast enhancement computed tomography (HCE-CT) in detecting the primary tumor. The primary tumor was demonstrated as having slightly low intensity compared with liver parenchyma and high intensity compared with the dilated bile duct on T1 weighted images. In contrast, MRI using Gd-DTPA, which was carried out in five cases, revealed intense enhancement of the tumor. As the differentiation between cholangiocarcinoma and dilated bile duct was difficult, it was concluded that the use of Gd-DTPA improves the efficacy of MRI in diagnosing cholangiocarcinoma. Gd-DTPA was also effective in differentiating the growth pattern of the tumor: the infiltrating type was demonstrated as thickening of the wall of the bile duct, the polypoid type as a soft tissue mass in the bile duct. Contrast MRI study is effective for the detection of cholangiocarcinoma. It is also expected to be effective in the staging diagnosis of cholangiocarcinoma.
 ...
PMID:[MR imaging of hilar cholangiocarcinoma--comparative study with CT]. 132 10

Eight patients affected with endocrine tumor of the pancreas were examined, within the same period of time, by MRI and CT. Results from those two examinations were similar for the detection of the primary tumor (succeeding to visualize the lesion 5 times out of 8) and the evaluation of locoregional and vascular extension. No tumor smaller than 3 cm was diagnosed by MRI. Most of cases the pancreatic tumor appeared as hypointense in T1 and hyperintense in T2 sequences. MRI was a little more efficient than CT for the detection of liver metastases. MRI seems to be an interesting method for the follow-up of those patients needing a regular and prolonged surveillance after primary tumor ablation.
 ...
PMID:[Role of MRI in the diagnosis of endocrine tumors of the pancreas]. 132 60

Metastatic tumors of the pituitary gland and parasellar region are unusual and are generally observed both in an advanced phase of the disease and at autopsy. The occurrence of symptomatic lesions is however quite rare. Though some clinical features may suggest the presence of a metastasis, the diagnosis is unlikely both clinically and radiologically and more common pituitary lesions are generally suspected. The Authors present two very unusual cases in which the pituitary lesions represented the onset symptoms of an otherwise unknown malignancy. Moreover the increased survival of cancer patients and the routine utilization of CT scan and MRI will probably induce, in the next years, a more frequent discovery of pituitary metastases. The Authors suggest that the diagnosis of pituitary metastases should be more closely considered even in the absence of a known primary tumor.
 ...
PMID:Pituitary metastases as presenting lesions of malignancy. 132 47

In patients with cervical metastases conventional examination by ultrasound, CT or MRI imaging often fails to identify an unknown primary tumor. Also the retrieval of a recurrent malignancy may be difficult. Scintigraphy, utilizing technetium-99m (v) dimercaptosuccinic acid was chosen for a prospective study in 17 patients to evaluate its properties for imaging metastasizing squamous cell carcinoma of the head and neck. Scintigraphic findings were correlated with the results of clinical examination and conventional imaging techniques. In all cases the primary tumor revealed good uptake of 99mTc(v)DMSA. Manifest cervical metastases could only be imaged in some cases. In future, therefore, 99mTc(v)DMSA scanning may be used for the detection of unknown primary tumors. However, it does not appear helpful in the evaluation of cervical nodes.
 ...
PMID:[Scintigraphic imaging of head and neck cancers with 99m technetium (v) dimercaptosuccinic acid. A prospective clinical study]. 133 46

We encountered a rare case of subfrontal schwannoma. A 55-year-old woman had received resection of a left frontal tumor because of hyposmia, at the age of 28 years. On June 10, 1989, she was admitted with the chief complaint of progressive contraction of visual field. Neurologic examination revealed anosmia, impaired vision and concentric contraction of visual field. Fundoscopy showed optic atrophy. CT examination demonstrated a calcified mass of mixed density which was occupying her nasal cavity, ethmoid sinus and anterior skull base. The lesion was enhanced with contrast medium. MRI clearly depicted the extension of the lesion and a low signal intensity area in the left frontal lobe as a postoperative scar. Angiography showed hypovascularity. The tumor was totally removed by bifrontal craniotomy on August 22, 1989. Infiltration into the brain or compression of the optic nerve was not detected. The dura on the cranial base side was damaged and lost by infiltration of the tumor, normal olfactory bulb was not able to be identified, and the cribriform plate was broken. The anterior skull base was reconstituted by covering the dural defect with cadaveric dura and the bony defect with a pericranium. HE staining showed Antoni A&B types of schwannoma. Postoperative course was uneventful. In this case, it is most likely that a remnant of the tumor resected when she was 28 years old had developed subfrontal schwannoma a long time after the operation, although the histological type at that time was unknown. It is also possible that a primary tumor in the nasal cavity or paranasal sinus may have extended into the cranium.(ABSTRACT TRUNCATED AT 250 WORDS)
 ...
PMID:[A case of subfrontal schwannoma]. 144 94

Invasive embryonal rhabdomyosarcoma of the prostate often extends superiorly into the bladder base requiring partial cystectomy as part of excision of the primary tumor. Three patients were studied with ultrasonography CT and MRI and showed the extension of the tumor superiorly and anterior to the bladder in the prevesical space of Retzius. Complete excision with bladder sparing was successful in two of the patients. The imaging of pelvic tumors in children (although well studied with ultrasonography, CT) is helped by MRI in the sagittal plane and/or lateral films of intravenous pyelograms and cystograms to establish the relation of the tumor to the bladder.
 ...
PMID:Three pediatric patients with extension of prostatic embryonal rhabdomyosarcoma anterior to the bladder into the space of Retzius. 150 89

Correlative studies of MRI and pathologic specimens were done in 35 patients with rectal cancer. The MR manifestations of the primary tumor and its invasion into the surrounding structures were investigated with reference to the staging of rectal cancer. Prone positioning and the procedure of hypotonic air-distension of rectum was the method of choice to depict the primary tumor and tumor invasion. The spin-echo (SE)pulse sequence with TR/TE: 500/32 ms (T1-weighted image) was selected to show the anatomical structures in the pelvis and tumor spread in the surrounding fatty space and lymph node metastasis. Owing to the reduced contrast between tumor invasion and fatty tissue and decreasing signal intensity on multi-echo T2-weighted images the long repetiting time (TR) pulse sequence could not provide significant contribution in tumor staging. The MR appearance of rectal carcinoma was categorized as polypoidnodular, cauliflowermassive and protuberant-ring types. Ulceration was often seen in the latter two types. Peripheral invasion often manifested as spotty-nodular, sawtoothed-wavy and tumefied shape with medium signal intensity on T1-weighted images. The presence of a lump of small nodes, round or oval nodules within 2 cm from the rectal wall or nodular mass in the perirectal fatty space could be considered as possible lymph node metastasis. Following the modified Dukes Staging System of rectal cancer proposed by Astler-Coller all patients were staged preoperatively and correlated with surgical specimens. The accuracy of staging was 74.3%, compatible with the results of studies published.
 ...
PMID:[Value of MR imaging in the staging of rectal carcinoma]. 157 12

In a rare case of teratocarcinoma of the pineal gland, MRI accurately depicted the primary tumor and diffuse enhancing drop metastases along the surface of the brain stem and the spinal cord.
 ...
PMID:Pineal teratocarcinoma with drop metastases: MR features. 163 Jun 17

From the surgical point of view it may be helpful to adopt the following guidelines in the treatment of patients with metastatic or locally recurrent colorectal cancer: 1. A gastroenterologist concerned with oncological patients should initiate adequate resectional treatment of the primary tumor. 2. In case of locoregional recurrences, every diagnostic effort (endoscopy, intraluminal ultrasound, angiogram, CT-scan, MRI) should be made to select patients with limited and resectable disease. 3. In patients with liver metastases amenable to surgical resection it is mandatory to rule out extrahepatic disease preoperatively as far as possible. 4. Prognostic factors deriving from tumor-biological data, extent of recurrent disease, and laboratory findings (CEA) must be taken into consideration when the decision whether to operate is to be made. These arguments should also be used to support non-operative treatment in patients with a type of recurrence that cannot be cured by surgery. 5. Postoperatively, all information (intraoperatively detected extrahepatic disease, tumor infiltrated resection margins, CEA not returning to normal levels) should be combined to classify patients according to whether they carry a high risk for a second tumor recurrence and should thus undergo additional treatment. In a "low-risk situation", further follow-up seems to be adequate.
 ...
PMID:[Reoperation in colorectal carcinoma with curative intention]. 164 13


1 2 3 4 5 6 7 8 9 10 Next >>