Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0677481 (urinary frequency)
 1,126 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
OFD1 protein 12.0
HPSE2 10.7
uroplakin II 9.7
ubiquitin specific protease 9.5
BUP 9.1
WNT2B 8.6
insulin-like growth factor binding protein 7 8.6
SCA17 8.6
GBA2 8.6
P4HB 8.4
TP-1 8.3
DRPLA 8.2
WNT11 8.1
WNT10A 8.0
uroplakin III 7.9
RCC 7.9
SCA7 7.8
urocortin 3 7.7
pTa 7.6
CRF2 7.5
HUC 7.2
SCC antigen 7.2
PGT 7.2
MSK1 7.0
CRFR1 6.9
HMT 6.8
apolipoprotein A-IV 6.7
SCA2 6.6
TAK 6.6
TRT 6.6
TRPML1 6.6
seminal plasma protein 6.5
Sho 6.5
Win 6.5
SGLT2 6.4
CRF1 6.4
oxytocinase 6.4
WNT5A 6.3
SCA1 6.3
vesicular acetylcholine transporter 6.3
APF 6.2
prostate specific antigen 6.2
SNS 6.1
GP1 6.1
pT1 6.1
SCA3 6.0
CHL 6.0
Kv1.4 5.9
UTI 5.9
cytochrome P450 2D6 5.9
beta-3 5.9
SCA6 5.9
C30 5.8
CK20 5.8
thyroid transcription factor-1 5.7
NGF protein 5.7
non-muscle 5.6
dach 5.6
HTN 5.6
version 3 5.6
GPT 5.6
SOM 5.5
5-HT2B 5.5
P2X2 5.5
HC1 5.5
Kallikrein 5.5
HIS3 5.4
P2X3 5.4
TRPM8 5.4
TSP 5.4
calcium/calmodulin-dependent protein kinase II 5.4
GRP 5.4
Was 5.3
sodium-glucose cotransporter 5.3
PVR 5.3
melastatin 5.3
prostate-specific antigen 5.2
RAP 5.2
P40 5.2
sigma receptor 5.2
Carcinoembryonic antigen 5.2
ARA 5.2
SRP 5.2
IA-2 5.2
TRPV4 5.1
SP6 5.1
CK7 5.1
MSA 5.1
enigma 5.1
melanin-concentrating hormone 5.0
ABS 5.0
class V 5.0
PDS 4.9
TRPV1 4.9
GLP 4.9
cytokeratin 7 4.9
glutamate pyruvate transaminase 4.8
IDO 4.8
period 2 4.8
purinergic receptor 4.8
SMD 4.7
FTA 4.7
SMAD2 4.7
PID 4.7
PBS 4.7
NK1 4.7
DAP 4.7
BK channel 4.6
CD99 4.6
SEP 4.6
CAS 4.6
urinary kallikrein 4.6
MCP-3 4.6
programmed death ligand 1 4.5
caldesmon 4.5
mast cell 4.5
muscarinic receptor 4.4
CBD 4.4
p51 4.4
ACR 4.4
sex hormone binding globulin 4.4
CTNNB1 4.4
CD43 4.4
cAMP response element binding protein 4.4
GCS 4.4
muscarinic acetylcholine receptor 4.4
She 4.4
fur 4.3
NSE 4.3
urocortin 4.3
A-II 4.3
calponin 4.3
CIS 4.3
PSS 4.2
CPA 4.2
N-acetyl-beta-D-glucosaminidase 4.1
gelsolin 4.1
DBP 4.1
interferon-beta 4.1
WIN 4.1
cytochrome aa3 4.1
CSA 4.1
neurofibromatosis 4.1
corticotropin-releasing factor 4.0
transient receptor potential vanilloid 1 4.0
occludin 4.0
CFA 4.0
P2X 4.0
smooth muscle actin 4.0
transthyretin 4.0
soluble guanylyl cyclase 4.0
PSA 4.0
GAD 3.9
cathepsin K 3.9
ARC 3.9
diaphorase 3.9
neurofibromatosis type 1 3.9
connexin 43 3.9
T11 3.9
inward rectifier 3.9
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Disease
stage II prostate cancer 14.8
stage I prostate cancer 14.8
Chronic vaginitis 13.8
Urethral tumor 13.8
Neuro-Behcet disease 13.2
Chronic interstitial cystitis 13.0
Hunner 12.9
Bacterial cystitis 12.8
Visceral gout 12.5
Painful Bladder Syndrome 12.2
Acute hemorrhagic cystitis 12.2
Pseudohyperparathyroidism 12.0
nocturia 11.7
interstitial cystitis 11.5
Retention cysts 11.5
Radiation cystitis 11.5
Polypoid cystitis 11.5
Overactive bladder 11.3
Eosinophilic cystitis 11.3
Vulvovaginal atrophy 11.2
Prostatic abscess 11.1
stage II endometrial cancer 11.0
Vacuolar myelopathy 10.7
Scrotum 10.7
Scrotum 10.5
trigonitis 10.5
urethrorrhagia 10.5
BPS 10.4
Urethral diverticulum 10.4
Colovesical fistula 10.4
airsickness 10.3
contracted bladder 10.2
urethral syndrome 10.1
Renal pelvis 10.0
Renal pelvis 10.0
Emphysematous cystitis 9.9
Chronic endometritis 9.9
chronic cystitis 9.9
Urethra 9.8
Urethra 9.8
ameboma 9.7
Urethra 9.7
lower urinary tract infection 9.7
urinary system cancer 9.6
recurrent cystitis 9.5
prostatic obstruction 9.4
cystitis 9.4
incontinence 9.3
Prostatitis 9.3
Nephrogenic adenoma 9.2
incontinence 9.2
vesiculitis 9.1
Primary dysmenorrhea 9.1
nocturnal leg cramps 9.1
Myopericytoma 9.1
Idiopathic hypercalciuria 8.8
Bone marrow depression 8.7
Bladder outlet obstruction 8.7
tabes 8.6
Low-grade fibromyxoid sarcoma 8.6
hydroureteronephrosis 8.6
neurogenic bladder 8.6
UFS 8.5
SCA17 8.5
papillary tumor 8.5
pyuria 8.4
Dyspareunia 8.4
Tubulointerstitial nephritis 8.3
acute cystitis 8.2
Bladder 8.2
Bladder 8.2
Bladder 8.2
OFD1 8.2
Penis 8.2
chronic urinary tract infection 8.1
prostatic adenoma 8.1
recurrent urinary tract infection 8.0
atrophic vaginitis 8.0
adenocarcinoma of unknown primary 8.0
Chronic prostatitis 8.0
prostatitis 7.9
parasympathomimetic 7.9
recurrent endometrial cancer 7.9
Penis 7.8
vaginal atrophy 7.8
ureterocele 7.8
adenocarcinoma of the bladder 7.8
ureterolithiasis 7.8
SCA7 7.8
stress incontinence 7.8
Asymptomatic bacteriuria 7.8
bladder infection 7.8
Plasmacytoma 7.7
xerostomia 7.7
Inverted papilloma 7.7
urethra 7.7
phimosis 7.7
ureteritis 7.5
Hemorrhagic cystitis 7.5
bladder neck obstruction 7.5
signet ring cell carcinoma 7.3
esophageal ulceration 7.3
urethritis 7.2
testicular neoplasm 7.2
SCA6 7.1
pineoblastoma 7.1
myoma 7.1
psychological impairment 7.0
uterine leiomyoma 7.0
Recurrent disease 7.0
carcinoma of the bladder 6.9
bacteriuria 6.9
transitional cell carcinoma of the bladder 6.8
leiomyoma 6.8
urinary tract infection 6.8
Pelvic inflammatory disease 6.8
diffuse goiter 6.8
vaginal discharge 6.8
hemangiosarcoma 6.8
low-grade lymphomas 6.7
Sexual dysfunction 6.7
hypernatremia 6.7
Mixed infection 6.7
bilateral cataracts 6.6
vaginitis 6.6
SCA2 6.6
pseudobulbar palsy 6.6
obstipation 6.6
disabling disease 6.6
paralytic ileus 6.6
sensory disturbance 6.6
pyonephrosis 6.6
epididymitis 6.5
transitional cell carcinoma 6.5
hydronephrosis 6.5
hormone refractory prostate cancer 6.5
eustachian tube dysfunction 6.5
prostatic adenocarcinoma 6.5
urolithiasis 6.4
HTLV-I 6.3
caruncle 6.3
peripheral primitive neuroectodermal tumor 6.3
ureter 6.3
petechiae 6.2
SCA1 6.2
thyroid storm 6.2
penicillin allergy 6.2
Hereditary spastic paraplegia 6.2
prostatic disease 6.1
renal clear cell carcinoma 6.1
Arthus reaction 6.1
Gitelman syndrome 6.1
Recklinghausen 6.1
generalized disease 6.0
Machado-Joseph disease 6.0
HAM 6.0
nephrogenic diabetes insipidus 5.9
bladder cancer 5.9
dysautonomia 5.9
mononeuritis 5.8
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Symptom
urinary frequency 14.8
bladder pain 12.1
increased abdominal size 12.0
strangury 11.7
burning on urination 11.2
dysuria 11.1
Prostatodynia 10.9
Lower urinary tract symptoms 10.8
abdominal rigidity 10.8
pubic pain 10.7
Urge incontinence 10.7
vaginal itching 10.7
nocturnal polyuria 10.6
frequent urination 10.5
Bladder distention 10.4
vaginal pain 10.2
ischuria 10.1
difficulty with urination 10.0
Vaginal dryness 9.6
tenesmus 9.6
change in stool 9.5
enuresis 9.1
Acute urinary retention 8.8
pelvic pain 8.7
pneumaturia 8.7
Urinary symptoms 8.5
prostatism 8.2
bedwetting 8.2
loss of taste 7.8
ataxic gait 7.7
lassitude 7.6
urethral discharge 7.6
rales 7.5
loin pain 7.4
testicular pain 7.4
blushing 7.3
Chronic pelvic pain 7.2
flank pain 7.2
giddiness 7.1
giddiness 7.1
polyuria 7.1
abdominal discomfort 7.0
constipation 7.0
dyschezia 7.0
polydipsia 6.5
Physical findings 6.4
decreased appetite 6.2
renal colic 6.1
abdominal fullness 6.1
chronic constipation 6.0
blurred vision 5.8
hot flashes 5.7
chills 5.7
bloating 5.7
discomfort 5.6
excessive sweating 5.6
discomfort 5.6
night sweats 5.6
paraparesis 5.4
clonus 5.3
chronic back pain 5.2
chest tightness 5.2
abdominal pain 5.2
photophobia 5.2
rigors 5.1
paresthesia 5.1
back pain 5.0
oliguria 4.9
dysarthria 4.9
dysesthesia 4.9
numbness 4.8
shortness of breath 4.8
heartburn 4.7
emaciation 4.7
colic 4.7
muscle rigidity 4.7
Postoperative pain 4.7
nausea 4.7
abnormal gait 4.6
nasal congestion 4.6
bradykinesia 4.6
vomiting 4.6
hot flushes 4.5
pallor 4.5
asthenia 4.4
pain 4.3
anosmia 4.2
anorexia 4.2
sciatica 4.2
spasticity 4.1
menopausal symptoms 4.1
weakness 4.1
ophthalmoplegia 4.1
ataxia 4.0
incoordination 4.0
cerebellar ataxia 4.0
lethargy 3.9
sneezing 3.9
diarrhea 3.9
paresis 3.9
leg pain 3.8
twitching 3.8
flushing 3.7
tense 3.7
tremor 3.6
stridor 3.6
wheezing 3.6
nausea and vomiting 3.6
dizziness 3.5
low back pain 3.5
Wind 3.4
dry eye 3.4
cough 3.4
sore throat 3.4
Ill 3.3
knee pain 3.3
acute abdomen 3.2
bone pain 3.2
fatigue 3.1
erythema 3.1
exertional dyspnea 3.1
epigastric pain 3.0
spasm 2.9
thinning 2.9
cyanosis 2.9
hemiplegia 2.8
dyspnea 2.8
myoclonus 2.7
syncope 2.6
headache 2.6
insomnia 2.4
cachexia 2.3
chest pain 2.3
hypothermia 2.3
sleepiness 2.1
anesthesia 2.1
myalgia 2.1
vertigo 2.0
arthralgia 2.0
dystonia 1.7
agitation 1.2
analgesia 1.0
overweight 0.1
collapse -0.0
seizures -0.5
Drug
Terodiline hydrochloride 14.2
Tiodazosin 12.8
Trospium 12.8
Tolterodine tartrate 12.6
Tolterodine Tartrate 12.5
Trospium chloride 11.7
Mictonorm 11.5
Ditropan 11.3
Sarpogrelate hydrochloride 11.1
Solifenacin succinate 11.0
Naftopidil 10.5
Carmofur 10.1
Demeclocycline 9.4
Darifenacin 9.2
Silodosin 9.1
Myobloc 8.9
Tolvaptan 8.6
Ovulen 8.2
Dutasteride 7.9
Fenoterol 6.9
TAK 6.8
IPD 6.6
Exenatide 6.5
DDAVP 6.5
Pilocarpine 6.5
DDAVP 6.4
Hydrochlorothiazide 6.2
Pemetrexed 6.1
Omalizumab 6.1
Botox 6.1
Liraglutide 6.0
BoNT/A 6.0
Papaverine 5.9
ISP 5.9
BCG vaccine 5.7
Diurnal 5.6
VCR 5.5
Diphenhydramine 4.8
Hypaque 4.7
Gleevec 4.3
VCR 4.2
Atropine 4.1
9-THC 4.0
Estrogens 3.7
Adriamycin 3.6
Imatinib 3.5
pyridoxal phosphate 3.5
Vitamin A 3.2
CTX 3.1
Albumin 2.6
Angiotensin II 2.5
ICI 2.4
CTX 2.3
CTX 2.3
CSF 2.2
MAP 0.8
Leaf 0.4
IL-2 -0.0
Monit -0.3
Enzyme
GLO 6.1
prostate-specific antigen 5.3
botulinum neurotoxin 4.9
5alpha-reductase 4.7
5alpha-reductase 4.7
tryptase 4.3
glucocerebrosidase 4.3
cathepsin K 3.9
diaphorase 3.4
gamma-glutamyl transpeptidase 3.2
UDP-glucuronosyltransferase 3.1
enolase 2.9
NADPH-diaphorase 2.9
ceruloplasmin 2.5
alanine aminotransferase 2.4
diaphorase 2.3
kallikrein 2.2
NQO1 2.2
guanylate cyclase 1.7
elastase 1.6
CD10 1.5
lysozyme 1.4
aspartate aminotransferase 1.4
cholinesterase 1.2
acid phosphatase 1.1
thromboplastin 1.1
acetylcholinesterase 1.0
lactate dehydrogenase 1.0
alkaline phosphatase 0.8
MEK 0.6
phospholipase C 0.6
phosphodiesterase 0.6
creatine kinase 0.6
adenylate cyclase 0.6
trypsin 0.4
caspase-3 -0.3
renin -0.3
luciferase -0.4
focal adhesion kinase -0.6
ERK -0.8
protein kinase C -0.8
catalase -1.0
peroxidase -1.2
protein kinase -1.5
Compound
Propiverine 12.2
N-isopropylacetamide 12.0
Oxybutynin 11.1
Flavoxate 10.1
Tolterodine 10.1
Propantheline 9.9
1-azabicyclo[2.2.2]oct-3-yl 9.2
1-methyl-1H-indole 9.1
3,4-dihydroisoquinoline 9.1
1,3-dihydro-2H-benzimidazol-2-one 8.8
Enoxacin 8.3
cyclohexanecarboxamide 7.9
Tamsulosin 7.8
Dimethoate 7.6
Glimepiride 7.6
Dehydroepiandrosterone sulfate 7.5
HIS 6.7
IPD 6.6
4-methylphenyl 6.6
Pilocarpine 6.5
HAQ 6.2
Epirubicin 6.1
MCH 6.0
Ketamine 5.9
Papaverine 5.9
Sertraline 5.9
Allergan 5.9
PPADS 5.8
Levetiracetam 5.8
Sphingosine 1-phosphate 5.8
NMP 5.6
GPT 5.6
Mitoxantrone 5.5
Hydrochlorothiazide 5.5
Mitoxantrone 5.4
Kallikrein 5.4
Diphenhydramine 5.4
CBDCA 5.3
CBDCA 5.3
Levamisole 5.2
VM-26 5.0
CCC 4.9
QNB 4.9
Imipramine 4.8
Imipramine 4.8
hippurate 4.8
Azathioprine 4.8
PID 4.8
PID 4.7
Phenylalanine 4.7
methylhistamine 4.7
DAP 4.7
DAP 4.7
Dipyridamole 4.6
Dipyridamole 4.6
Dipyridamole 4.6
Dipyridamole 4.6
Linoleic acid 4.6
Baclofen 4.5
FTA 4.5
Hematoxylin 4.4
Capsaicin 4.4
MMC 4.4
Acetone 4.3
Prazosin 4.3
Benin 4.2
CPA 4.2
Substance P 4.1
Atropine 4.1
CPA 4.1
CPA 4.0
T11 4.0
Chloroquine 3.9
Chloroquine 3.9
DBP 3.9
beta-alanine 3.8
CPA 3.8
neopterin 3.8
ALP 3.7
Penicillin 3.7
DBP 3.7
A 71 3.7
Vasopressin 3.6
BCG 3.6
Lithium 3.6
5-FU 3.6
T10 3.6
Parenteral 3.5
DPP 3.5
DIC 3.4
pyrrolidine 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.4
oxalic acid 3.3
pyrrolidine 3.3
Methicillin 3.2
Vitamin A 3.2
Androgen 3.2
Guo 3.2
Sodium 3.2
IMP 3.2
A 1 3.2
VP-16 3.2
Diazepam 3.1
8-OHdG 3.1
CTX 3.1
oxalic acid 3.1
INH 3.0
PGE2 3.0
Abbott 2.9
STZ 2.9
DMSO 2.8
hyaluronic acid 2.8
Adriamycin 2.8
creatinine 2.7
Optimal 2.7
Angiotensin II 2.7
Guo 2.6
His 2.5
Methotrexate 2.5
THP 2.5
THP 2.4
barium 2.4
Testosterone 2.2
Testosterone 2.2
diacetate 2.2
Glutamate 2.1
ICI 2.1
noradrenaline 2.1
Isoproterenol 2.1
Ang II 2.0
DTPA 2.0
Letter 2.0
potassium 1.9
prostaglandin E1 1.9
2-oxoglutarate 1.9
H2S 1.9
A 3 1.9
bromide 1.7
Salt 1.7
CAT 1.7
CAT 1.7
GMP 1.6
MAP 1.6
CAT 1.6
nitric oxide 1.5
pyrimidine 1.5
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