Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0677481 (urinary frequency)
 1,126 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A case of non-Hodgkin's lymphoma is reported. A 71-year-old man presented with complaint of dysuria and urinary frequency. Rectal examination and CT scan revealed a bulky mass in the rectovesical space. Transperineal needle biopsy of the tumor revealed non-Hodgkin's lymphoma, large cell type, diffuse. The patient received combination chemotherapy of adriamycin, cyclophosphamide, vincristine, prednisolone and pepleomycin. After two days the tumor was marvelously reduced in size, and partial response (PR) by CT was achieved after two months. PR was sustained for two months with cyclophosphamide, vincristine and prednisolone. However, the tumor progressed gradually, and he died five months after the first treatment and two additional courses of chemotherapy. Autopsy showed a 1,700 g bulky mass in the rectovesical space. The mass was covered with peritoneum and had a fistula from rectum to central necrosis of the tumor. Nine cases of the non-Hodgkin's lymphoma with complaint of dysuria have been reported in Japan before our case, which seemed to arise from the submucosal tissue of anterior rectal wall, prostate or lymphatic tissue of rectovesical space.
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PMID:[A bulky mass non-Hodgkin's lymphoma with dysuria in the rectovesical space]. 223 64

The patient was a 34-year-old male. He visited a community hospital complaining of macroscopic hematuria and pollakiuria. Cystoscopic examination demonstrated a bladder tumor. Transurethral resection of the bladder tumor (TUR-Bt) was performed. Histological examination disclosed malignant lymphoma (non-Hodgkin's lymphoma, mixed type). The tumor was classified into the B cell type by the immunohistological staining with surface antigens. He was referred to St. Marianna University, School of Medicine for chemotherapy. Pelvic computed tomography (CT) after admission demonstrated a tumor with a wide pedicle located in the vesicle triangle extending to the posterolateral wall of the bladder. No abnormalities were found in other organs. After establishment of the diagnosis of primary bladder malignant lymphoma, 6 courses of chemotherapy (adriamycin, vincristine, cyclophosphamide, prednisolone, etoposide, methotrexate) were performed. The tumor disappeared completely on imaging studies after chemotherapy. Biopsy of the bladder disclosed no abnormal tissues. No evidence of recurrence or metastasis was found 5 years after chemotherapy.
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PMID:[A case of primary malignant lymphoma of the bladder]. 978 99

Primary non-Hodgkin's lymphoma of the ovary is a rare occurrence. An ovarian involvement by non-Hodgkin lymphoma (NHL) may include one of the four subtypes of lymphoma: diffuse large B-cell lymphoma, Burkitt's lymphoma (BL), lymphoblastic lymphoma or anaplastic large cell lymphoma. Burkitt's lymphoma is a rare entity with a specific poorly differentiated pattern.Most women experience an ovarian BL with abdominal pelvic pain, abnormal vaginal bleeding, bowel obstruction, urinary frequency, incontinence and abdominal mass. Sometimes these warning signs may be absent, causing a late and more difficult diagnosis.Here we report a case of a primary ovarian Burkitt's lymphoma with bilateral involvement in a 57 year old patient. She firstly presented neurological symptoms in the upper limbs and she was treated with surgery and combined chemotherapy. The diagnosis of malignant lymphoma was established after bilateral adnexectomy and histological study of the excised tissue.
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PMID:An atypical presentation of sporadic ovarian Burkitt's lymphoma: case report and review of the literature. 2382 66