Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0677481 (urinary frequency)
 1,126 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We report on a 69 year-old patient with a leiomyoma of the seminal vesicle who presented with dysuria and pollakiuria. The rectal examination revealed a large, hard mass in an area corresponding to the seminal vesicle. The prostate was suspicious of malignancy, but transrectal needle biopsy specimens were negative. We managed the patient by prostatovesiculectomy. The pathological findings and the immunohistochemical staining pattern of smooth muscle with antibodies against beta-actin and desmin confirmed the diagnosis of a leiomyoma of the left seminal vesicle. To our knowledge, this kind of tumour is exceedingly rare, with only a few cases reported in the literature.
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PMID:Leiomyoma of the seminal vesicle. 896 99

Leiomyosarcomas are rare malignant tumors of the kidney. They may arise from the renal capsule, renal vein, renal pelvic musculature or renal parenchyma. Renal pelvis is an uncommon site of occurrence, with around 10 cases reported in the literature so far. Here we present a 60-year-old male who presented with increased urinary frequency, lower limb weakness, anorexia and weight loss. Imaging showed a right renal mass. A renal cell carcinoma was suspected clinically. A right nephrectomy was performed, which showed a large circumscribed mass in the hilar region. Histology revealed a tumor mass arising from the renal pelvis. The tumor was composed of spindle cells arranged in fascicles. Immunohistochemistry showed tumor cells to be positive for smooth muscle actin (SMA) and desmin (Des) and negative for cytokeratin (CK), HMB 45, CD117 (C-kit), and CD34. That confirmed the diagnosis of leiomyosarcoma.
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PMID:Leiomyosarcoma of the renal pelvis. 1980 70