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Query: UMLS:C0677481 (urinary frequency)
 1,126 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The results of 350 cystoscopic studies, are presented. In 85.7%, urinary incontinence was present, and in 72% one or more of the following symptoms were present: urgency, dysuria, urinary frequency, vesical tenesmus and nycturia. The following were analyzed: age, parity, uroculture and its relation to cystoscopic findings. Most of the patients (64.5%) were 40 to 60 years old, 54% had seven or more deliveries. Most frequent diagnoses were: urethritis alone or with trigonitis (66.8%) and urethral stenosis (meatus) in 31.4%. Uroculture was done in 96% and it was positive in 20% and negative 76%. In 88% of the patients with a negative uroculture, there were other lesions shown by urethrocytoscopy. From 300 patients with urinary incontinence, only in 155 it was confirmed objectively.
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PMID:[Value of cystoscopy in the study of the urogynecological patient]. 74 91

Medical records of 68 horses with urolithiasis were examined. Calculi were in the bladder in 47 horses, urethra in 11 horses, kidneys in 15 horses, and ureter in two horses. They occurred at several sites in six horses. Common clinical signs included hematuria, altered micturition (pollakiuria, dysuria, urinary incontinence), and tenesmus. Weight loss, possibly attributable to chronic renal failure and colic, was associated more commonly with renal and ureteral calculi. Weight loss also occurred in 13% of horses with cystic calculi only. In male horses, most cystic calculi were removed by perineal (ischial) urethrotomy under epidural anesthesia. Although there were few surgical complications with urethrotomy, seven of 15 horses with follow-up suffered recurrent urolithiasis.
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PMID:Urolithiasis in 68 horses. 158 59

To induce an experimental model of bacterial cystitis, ten preconditioned dogs underwent bladder irritation with a 0.1% alcoholic solution of salicylic acid followed in 24 hours by an intravesicular infusion of Proteus mirabilis. The dogs were observed for the following 14 days (five dogs) and 17 days (five dogs) and then euthanatized and necropsied. Tenesmus, dysuria, hematuria, and pollakiuria occurred in all dogs, but the severity of these signs diminished with time. The total white cell, neutrophil, and monocyte counts in the peripheral blood increased and urinalysis results were consistent with infection and severe inflammation. The infection persisted for the duration of the study, although the average quantitative bacterial count in urine progressively declined. No changes occurred in the measured clinical chemistry values. Severe inflammation was present on gross examination of the bladder and microscopic examination of the bladder, prostate, and renal pelvis. Less severe inflammation was present on microscopic examination of the urethra and ureter.
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PMID:A model for experimental bacterial cystitis in the dog. 377 58

The activity of pidotimod ((R)-3-[(S)-(5-oxo-2-pyrrolidinyl) carbonyl]-thiazolidine-4-carboxylic acid, PGT/1A, CAS 121808-62-6) was studied vs. placebo in a double-blind, randomized, multicentre trial, involving 60 pediatric patients with recurrent urinary tract infections. Recovery from acute events was quicker with pidotimod than with placebo (9.6 vs. 12.3 days). In treated patients antibiotic therapy was shorter (6.9 vs. 8.3 days) and main symptomatic parameters (body temperature, vesical tenesmus, stranguria, pollakiuria, total number of symptoms, total symptomatic intensity, rate of asymptomatic patients, haematuria, leukocyturia, positive urinary culture) receded quickly. In patients receiving the drug as well as in patients treated with placebo changes in laboratory parameters were observed, indicating recovery from the acute infectious disease. A significant trend to normalization of the immune response, expressed by chemotaxis and index of leukocyte phagocytosis, was found only in patients treated with pidotimod. After the acute episode a significant decrease of risk of relapses (69%) was observed in these patients. If a relapse occurs, the response of treated patients is quicker (duration of fever, total time of relapses) than for control patients. These findings allow to correlate the individual immune response activation to the resistance to recurrent infections and also to a better response to therapy if the disease occurs and becomes clinically relevant. No side effects were observed. Mild reactions (4 nausea/vomiting, 1 erythema) occurred only in 5 patients (2 pidotimod, 3 placebo) but were attributed to concomitant antibiotic therapy. No alterations of main laboratory parameters were found. These findings confirm the tolerability of the drug also in long-term treatment.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:Therapeutic efficacy and safety of pidotimod in the treatment of urinary tract infections in children. 785 49

It is known that a great number of subjects, mainly little girls, frequently go to pediatric's observation for recurrent episodes of pollakiuria, dysuria or burning miction. They often complain enuresis, sometimes tenesmus so intense that they arrive at the incontinence (urge incontinence). Many of these cases, quickly defined as cystitis, really revealed that they weren't. Repetitively negative bacteriologic examinations allow us to classify them as "sham syndromes", as Stephens called them. According to what we said above, we wondered whether any recurrent cystitis are not favoured by missed observation of definite rules.
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PMID:[Recurrent cystitis in children: do predisposing factors exist for its onset?]. 826 56

A case is reported of the presence of an intrauterine device into the bladder due to uterine perforation with calculus formation in a 39 year old woman, with two pregnancies after its installation. The patient was seen for complaints of pelvic pain, pollakiuria, dysuria and tenesmus, without uterine sintomatology. The case was studied in July of 1993 in the General Hospital "Vicente Guerrero" of Acapulco. To our knowledge only 19 previous cases have been reported in the literature of migration of an intrauterine device into the bladder with calculus formation. The literature is reviewed and we discuss the clinico-radiological findings.
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PMID:[Uterine perforation and localization of an IUD in the bladder associated with bladder calculosis. Report of a case and review of the literature]. 854 21

Nephrogenic adenoma is a benign epithelial tumour localised at the level of the urothelium and caused by metaplasia of the urothelium following prolonged aggressive stimulation over time, for example trauma or chronic urinary infection. Even a diverticulum, in whatever site it is localised, is subject to an increased risk of neoplastic transformation of the urothelium. It above all affects male subjects, with a male/female ratio of 3:1 over the age of 20, which is inverted in younger subjects. The most frequently affected site is the vescical trigonum in 72% of cases, followed by the pelvic tract of the ureter (19%) and urethra. The majority of patients is asymptomatic or reports aspecific symptoms: the most frequent picture is macroscopic hematuria, owing to the rich vascularisation of the tumour. This is followed by irritative type signs such as pollakiuria, strangury, posturination dripping and sometimes painful tenesmus. Differential diagnosis is necessary for pale cell adenocarcinoma, parauretral cysts and Gartner duct's cysts which may be associated with urethral diverticulum, localised on the bottom, and rarely symptomatic. Diagnosis is based on retrograde urethrography, cystography and endoscopic tests, with biopsy if necessary. NMR provides further details regarding the site, localisation and benign or malignant nature of the lesion. Treatment is surgical: endoscopic (transurethral) if the dimension are limited, or traditional using a suprapubic or transvaginal route if it is associated with diverticulum. Prognosis is discrete and depends on the timeliness with which the factors predisposing metaplasia are eliminated.
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PMID:[Nephrogenic adenoma arising from an urethral diverticulum in a female. Report of a case and review of the literature]. 1022 60

The spillage of gallstones into the peritoneal cavity from iatrogenic perforation of the gallbladder that occurs during laparoscopic cholecystectomy can result in late and serious complications. We report a case of vesical granuloma with symptoms of dysuria, pollakiuria, and vesical tenesmus that occurred 23 months after a laparoscopic cholecystectomy. Preoperative diagnostic evaluation showed a 3-cm vesical neoformation. A partial cystectomy was performed; macroscopic and histologic examination documented a central nidus of fragmented gallstones and a picture of chronic granulomatous inflammation. Although complications related to unretrieved gallstones that spill into the peritoneal cavity during laparoscopic cholecystectomy are rare, they are being reported with increasing frequency. Therefore, it is important to use tools and techniques that prevent lacerations of the gallbladder and involve retrieval of spilled gallstones.
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PMID:The vesical granuloma: rare and late complication of laparoscopic cholecystectomy. 1182 61

Introduction. Chronic inflammation of the urinary bladder (CIB) is a disease entity which mostly concerns young women and which is connected with their short urether and vicinity of vagina sexual activity. Frequent recidication, in spite of use of new generation of antibiotics - often of considerable cost - have a significant influence upon life of the patients. Side-effects connected with frequent use of antibiotics are also an important factor to consider.<br /> Aim. The life discomfort of the patients, frequently low effectiveness and side-effects of antibiotherapy, numerous cases of recidivation were the reasons of application of medical ozone in chronic inflammation of the urinary bladder.<br /> Material and method. During 18 months oxygen-ozone mixture was applied directly to the blader in case of 72 patients, to 65 women, that is 90% of patients, and to 7 men, that is 10% of patients. The age group was 19 to 67, with the average age of 36. In case of men, the age group was from 38 to 51, with the average age of 44. The number of procedures, depending both on bacteriological results and subjective symptoms, veried from 10 to 18. Ecery patient, prior to the ozonotherapy underwent general urine analysis and bacteriological tests; also subjective symptoms as pollysis and bacteriological tests; also subjective symptoms as pollakiuria, pain and burning during miction, and pressing tenesmus were estimated, according to QL life comfort scale.<br /> Those tests were repeated three and six months after the ozonotherapy procedures.<br /> Results. In the women group (in all cases) statistically significant improvement of life comfort was noted. Results of bacteriological tests after one month and three months were germ-free, after six months bacteriological results of 4 patients, that is 6% showed initial results with relapse of subjective symptoms. Which are statistically significant improvement in the case of remaining 47 patients, that is 72% germ-free culture were gained and lack of subjective symptoms. In the 6 patients (that is 86%) men group, after six months, in all cases germ-free-culture and lack of subjective symptoms were gained.<br /> Conclusion. Application of ozonotherapy in treatment of chronic inflammation of the vladder is a of significant statistical effectiveness method, and what is more cheap and with low risk in performance.
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PMID:Application of ozonotherapy in chronic inflammation of the urinary bladder. 1803 16

We report a case of marginally resectable gastrointestinal stromal tumor (GIST) in the pelvis treated with neoadjuvant intent before subsequent successful surgical resection. A 46-year old man presented with urinary frequency and rectal discomfort with tenesmus. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed a 12 cm diameter mass between the bladder and rectum and the margin of the tumor and prostate was unclear. No metastases were evident. Trans-rectal needle core biopsy confirmed c-kit positive GIST. Because of the locally advanced nature of the tumor,immediate surgical resection would have required total pelvic exenteration with eternal colostomy and urinary diversion. Therefore,the patient was treated with imatinib mesylate 400 mg daily in anticipation of adequate tumor size reduction to enable a more simplified surgical approach. After 3 months of imatinib therapy,MRI demonstrated a reduction in tumor size of 60%. Consequently,a complete surgical resection including the bladder,prostate and part of the sigmoid colon with temporary ileostomy and ileal conduit was performed. Pathological findings of the resected specimen showed widespread degeneration with cystic changes,necrosis, and hypocellularlity,as well as nodules of residual viable c-kit positive tumor cells. The patient has been treated with imatinib mesylate for 39 months following the operation without tumor recurrence.
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PMID:[Successful resection of a gastrointestinal stromal tumor in the pelvis with imatinib mesylate as neoadjuvant therapy]. 2158 85


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