Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0600142 (hot flushes)
 1,242 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
estrogen receptor 77
Sep 70
FSH 60
aromatase 50
LHRH 33
follicle-stimulating hormone 32
prolactin 22
oestrogen receptor 15
hormone receptor 14
Mol 14
alkaline phosphatase 13
neurokinin B 12
HDL 12
insulin 11
progesterone receptor 11
prostate-specific antigen 10
Hop 9
CYP2D6 9
kisspeptin 9
sex hormone-binding globulin 8
Men 8
osteocalcin 8
PRL 7
beta-endorphin 7
calcitonin 7
cytochrome P450 6
NK3 receptor 6
Pol 6
C30 5
She 5
Ki-67 4
BMD 4
ATAC 4
GABA 4
estrogen receptor alpha 4
GnRH receptor 4
dynorphin 4
renin 4
FACT 4
Prolactin 4
Calcitonin 3
WHI 3
reserved 3
delta 4 3
epidermal growth factor receptor 3
CYP 3
GPT 3
CEE 3
Aromatase 3
prothrombin 3
CO2 3
hemoglobin 3
corticotropin-releasing factor 2
adrenocorticotropic hormone 2
HER2 2
parathyroid hormone 2
growth hormone 2
cage 2
ACTH 2
PSA 2
CBT 2
ANOVA 2
CBG 2
androgen receptor 2
AVP 2
TTP 2
sex hormone binding globulin 2
thyroxine-binding globulin 2
CS2 2
antithrombin III 2
MRS 2
enigma 2
fibrinogen 2
collagen 2
apolipoprotein B 2
cytochrome P450 2D6 2
IVF 2
short form 2
CDS 2
NK3R 2
TRH 2
Gen 2
Neurokinin B 2
ESX 2
PMS 2
NCF 2
vascular endothelial growth factor 2
L17 1
NKB 1
visfatin 1
4E-BP1 1
VHL 1
reductase 1
catechol-O-methyltransferase 1
MOS 1
period 2 1
DBP 1
TOR 1
Bak 1
ESR2 1
NAG 1
CYP3A4 1
angiotensinogen 1
DHEAS 1
elastin 1
proliferating cell nuclear antigen 1
angiotensin II 1
EPT 1
synaptophysin 1
period 3 1
PSS 1
amyloid precursor protein 1
BIG1 1
albumin 1
neu 1
acid phosphatase 1
A-I 1
HCG 1
calcium channel 1
caspase 7 1
NHS 1
STAR 1
GDS 1
GCS 1
spermatozoa 1
thyrotropin-releasing hormone 1
Sex hormone-binding globulin 1
mammaglobin 1
5-HT1B 1
TAK 1
TNF 1
caspase-9 1
corticosteroid binding globulin 1
leptin 1
thrombin 1
cytochrome 1
CRF 1
MGA 1
adrenomedullin 1
apoE 1
prostatic acid phosphatase 1
nuclear receptor 1
calmodulin 1
sclerostin 1
IGF-1 1
aryl hydrocarbon receptor 1
Estrogen receptor 1 1
HTR 1
long chain 1
MRI 1
MAO-A 1
Orexin 1
superoxide dismutase 1
DES 1
RAD 1
GPR54 1
transporter 1 1
melanin-concentrating hormone 1
sterol regulatory element-binding protein-1c 1
catenin 1
organic anion transporting polypeptide 1
galanin 1
GMP 1
HTX 1
vesicular glutamate transporter 2 1
GRP78 1
alpha 1-antitrypsin 1
chromogranin A 1
BRL 1
CTB 1
Ang II 1
proopiomelanocortin 1
apolipoprotein 1
SBP 1
CD56 1
c-fos 1
endothelin-1 1
CYP3A 1
platelet-derived growth factor 1
neurotensin 1
HSP70 1
mineralocorticoid receptor 1
tyrosine kinase 1
duo 1
orexin 1
TGF-beta 1
eukaryotic translation initiation factor 4E 1
anonymous 1
GATA3 1
glycodelin 1
NALP3 1
cholecystokinin 1
JAMA 1
WIN 1
PRA 1
LHbeta 1
TTK 1
OTC 1
CTX 1
mTOR 1
nerve growth factor 1
glucagon 1
ISA 1
caspase-3 1
STD 1
VIP 1
adipokine 1
PEP 1
carcinoembryonic antigen 1
MIB 1
REM 1
gut 1
Intermedin 1
CAS 1
ER beta 1
STH 1
GAF 1
FACE 1
SPA 1
gp17 1
CYP2B6 1
ALP 1
carnitine palmitoyltransferase 1
MRC 1
TTR 1
BRI 1
fatty acid synthase 1
Bcl-2 1
TAT 1
ICD 1
AMH 1
ASL 1
ASA 1
GTT 1
GRP 1
Cytochrome P450 1
THP 1
CCK-4 1
interferon 1
SULT1E1 1
acetylcholinesterase 1
catalase 1
CYP2C19 1
cytokine 1
glutamate pyruvate transaminase 1
CD105 1
monocyte chemoattractant protein-1 1
5-HT2A 1
nodal 1
PHS 1
cytokeratin 1
NOT 1
tumor necrosis factor 1
EDRF 1
osteogenic 1
Sclerostin 1
HSP72 1
CAM 1
bone morphogenetic protein 1
EPO 1
rhodanese 1
Leydig cell 1
transforming growth factor-beta 1 1
5-HT1A 1
IGFBP3 1
PAIS 1
version 3 1
osteosarcoma 1
PPD 1
TRP 1
EMA 1
ARH 1
CAF 1
Disease
breast cancer 277
osteoporosis 136
depression 129
cancer 128
prostate cancer 85
cardiovascular disease 55
amenorrhea 49
endometriosis 43
uterus 39
endometrial cancer 38
sleep disturbances 35
tumor 33
endometrial hyperplasia 31
carcinoma 27
vaginal atrophy 26
gynecomastia 24
hypertension 23
sexual dysfunction 22
stroke 20
metastases 19
infertility 17
xerostomia 15
vaginal discharge 15
diabetes 14
metastatic breast cancer 13
Alzheimer's disease 13
pruritus 13
uterine leiomyoma 12
hypogonadism 12
premenstrual syndrome 12
anemia 11
impotence 11
menopausal syndrome 11
ovarian cancer 10
cold 10
incontinence 10
myocardial infarction 9
vagina 9
leiomyoma 9
migraine 8
emotional instability 8
heart disease 8
Prostate Cancer 8
Best 8
obesity 7
cognitive impairment 7
sleep disorders 7
major depressive disorder 7
recurrent breast cancer 7
coronary artery disease 7
coronary heart disease 7
erectile dysfunction 7
postmenopausal bone loss 7
atherosclerosis 7
atrophic vaginitis 6
ovarian cysts 6
rash 6
metabolic syndrome 6
epilepsy 6
dementia 6
uterine cancer 6
deep vein thrombosis 6
mental illness 5
precocious puberty 5
myoma 5
West 5
hypercholesterolemia 5
dyspepsia 5
cervical cancer 5
panic disorder 5
acne 5
pulmonary embolism 5
premature menopause 5
incontinence 5
premature ovarian failure 5
anxiety disorders 4
clinical depression 4
BMD 4
Pituitary 4
myelosuppression 4
secondary amenorrhea 4
adenocarcinoma 4
confusion 4
galactorrhea 4
type 2 diabetes 4
MCF 4
galactorrhea 4
psychological distress 4
hyperprolactinemia 4
tumor growth 4
dysphoria 3
abortion 3
polycystic ovary syndrome 3
endometrial adenocarcinoma 3
thrombophlebitis 3
seborrheic dermatitis 3
postpartum depression 3
myocardial ischemia 3
melancholia 3
Vulvovaginal atrophy 3
essential hypertension 3
carcinoid 3
SEM 3
lymphedema 3
postherpetic neuralgia 3
Parkinson's disease 3
hyperandrogenism 3
stress incontinence 3
panic attacks 3
cystitis 3
leukopenia 3
emotional distress 3
hallucinations 3
heart failure 2
malnutrition 2
dyslipidemia 2
tumor progression 2
AIDS 2
Steroids 2
testicular cancer 2
Still 2
arthritis 2
renal impairment 2
TTP 2
social stress 2
Ovary 2
CDS 2
colon cancer 2
thrombocytopenia 2
prolapse 2
hyperlipidemia 2
Estrogen deficiency 2
premature labor 2
premenstrual dysphoric disorder 2
gallstones 2
vaginal candidiasis 2
bone metastases 2
vaginal infection 2
paroxysmal supraventricular tachycardia 2
chronic disease 2
peripheral neuropathy 2
MRS 2
PMS 2
bipolar disorder 2
carcinoma of the breast 2
HIV 2
meningioma 2
primary tumor 2
hypercalcemia 2
IVF 2
plaque 2
hyperthyroidism 2
epithelial ovarian cancer 2
STD 2
osteoporotic fracture 2
neuroticism 2
suicide 2
prostatic adenocarcinoma 2
PSA 2
fibromyalgia 2
dyskinesia 2
Dependence 2
ductal carcinoma in situ 2
Hodgkin's disease 2
TTP 2
cardiovascular risk factor 2
hypoglycemia 2
fits 2
hypomenorrhea 1
Adhesion 1
prostatic disease 1
renal disease 1
toxoplasmosis 1
hyperglycemia 1
gestational trophoblastic disease 1
posttraumatic stress disorder 1
pheochromocytoma 1
renal cyst 1
craniopharyngioma 1
trisomy 1
psychological stress 1
congestive heart failure 1
adjustment disorder 1
muscular atrophy 1
dermoid cyst 1
Muckle-Wells syndrome 1
seminoma 1
pathological personality 1
Pelvic endometriosis 1
carcinoid syndrome 1
psychoactive substance abuse 1
Prinzmetal 1
derealization 1
psychosomatic disorders 1
myelofibrosis 1
Gallbladder disease 1
endocrine disorder 1
Autoimmune oophoritis 1
bends 1
Rust 1
psychosis 1
delayed puberty 1
chronic obstructive pulmonary disease 1
FBD 1
Sheehan's syndrome 1
Wells 1
pulmonary edema 1
emphysema 1
fibrocystic breast disease 1
illusion 1
syphilis 1
acute leukemia 1
Pseudopregnancy 1
immunodeficiency 1
hepatitis 1
Pelvic inflammatory disease 1
Sleep disturbance 1
learning disability 1
lupus 1
upper respiratory infection 1
CTX 1
infiltrating ductal carcinoma 1
PSS 1
psychiatric diagnosis 1
nasopharyngitis 1
Sjogren's syndrome 1
asthma 1
osteosarcoma 1
MWS 1
neutropenia 1
fibromatosis 1
carcinoma of the breast 1
locally advanced cancer 1
HTX 1
agranulocytosis 1
RDA 1
colorectal cancer 1
demineralization of bone 1
urethra 1
cancer relapse 1
thyroid cancer 1
interstitial pneumonia 1
urethritis 1
PHS 1
Male hypogonadism 1
bladder cancer 1
azoospermia 1
Surgical menopause 1
relapsing fever 1
warts 1
seminal vesicles 1
fear of cancer 1
pancreatitis 1
lung cancer 1
oligospermia 1
Postmenopausal symptoms 1
chronic renal failure 1
major depressive episode 1
bone disease 1
retinal vein thrombosis 1
Lyme disease 1
Mitchell 1
neuropathy 1
phlebitis 1
pelvic inflammatory disease 1
HTX 1
periodontal disease 1
drunk 1
gestational diabetes mellitus 1
urticaria 1
Thymus 1
endometrial stromal sarcoma 1
unipolar depression 1
lung metastases 1
Withdrawal bleeding 1
myasthenia 1
systemic disease 1
Atrophic 1
restless legs syndrome 1
ovarian dysfunction 1
NHS 1
Hippel 1
parkinsonism 1
Endometrial atrophy 1
GAD 1
ICD 1
lung disease 1
Female sexual dysfunction 1
Schistosoma mansoni infection 1
tumorigenesis 1
oophoritis 1
bronchitis 1
carpal tunnel syndrome 1
dyschromia 1
fatty liver 1
mastopathy 1
diabetic neuropathy 1
intermittent claudication 1
sleep apnea 1
pulmonary fibrosis 1
glucose intolerance 1
neurotic depression 1
flutter 1
vaginitis 1
carcinogenesis 1
Down syndrome 1
pemphigoid 1
Thymus 1
CHH 1
varices 1
liver disease 1
acute pancreatitis 1
polycythemia vera 1
PSS 1
lichen planus 1
CAM 1
vascular disease 1
vascular headache 1
Jensen 1
porphyria 1
hepatocellular carcinoma 1
urinary system cancer 1
DES 1
aggressiveness 1
venous insufficiency 1
Thymus 1
lipid disorder 1
cystic fibrosis 1
bronchitis 1
CES 1
Vasomotor disturbance 1
delirium 1
hormone deficiency 1
gonadal dysgenesis 1
lupus 1
fallopian tube 1
autoimmune disease 1
systemic lupus erythematosus 1
amyotrophic lateral sclerosis 1
HCG 1
disorientation 1
transient ischemic attack 1
regional pain syndrome 1
Dubin-Johnson syndrome 1
spinal cord compression 1
hypoactive sexual desire disorder 1
gonococcal 1
ileus 1
PSS 1
Dyspareunia 1
gonadoblastoma 1
head and neck cancer 1
genital warts 1
Central precocious puberty 1
neurological disease 1
mammary tumor 1
EMA 1
adenoma 1
dysthymia 1
Merkel cell carcinoma 1
genital herpes 1
renal cell carcinoma 1
hyperviscosity syndrome 1
testicular feminization 1
ARH 1
rosacea 1
reactive depression 1
schizophrenic psychosis 1
toxemia 1
nystagmus 1
macular degeneration 1
obstructive sleep apnea 1
addiction 1
Primary insomnia 1
Turner syndrome 1
proctitis 1
dermatitis 1
hamartoma 1
Symptom
hot flushes 1242
hot flashes 317
menopausal symptoms 185
night sweats 95
headache 86
fatigue 83
pain 74
insomnia 68
nausea 56
flushing 42
discomfort 31
discomfort 28
dizziness 28
arthralgia 25
vomiting 18
diarrhea 16
sleepiness 13
leg cramps 12
excessive sweating 12
myalgia 11
nausea and vomiting 11
Vaginal dryness 10
chills 10
mastalgia 10
erythema 9
anorexia 8
pelvic pain 8
peri-menopausal 8
Climacteric symptoms 7
back pain 7
abdominal pain 7
exhaustion 7
dyspnea 6
paresthesia 6
asthenia 6
seizures 6
numbness 6
vertigo 5
Crawling 5
forgetfulness 5
tremor 5
lassitude 5
weakness 4
overweight 4
Breast pain 4
bone pain 4
constipation 4
skin irritation 4
Ill 3
anesthesia 3
leg edema 3
thinning 3
chest pain 3
lethargy 3
bloating 3
cough 3
limb pain 3
memory loss 2
shortness of breath 2
dysuria 2
ataxia 2
menometrorrhagia 2
tingling 2
collapse 2
masculinization 2
hoarseness 2
cold sweats 2
agitation 2
abdominal cramps 2
apathy 2
irregular bleeding 2
stomach pain 2
tense 2
angina 2
nipple discharge 1
tinnitus 1
rhinorrhea 1
despair 1
Spotting 1
feeling depressed 1
hopelessness 1
Fatigability 1
hypersomnia 1
bitter taste 1
bewilderment 1
blurred vision 1
abdominal fullness 1
mental fatigue 1
respiratory distress 1
Wind 1
analgesia 1
feeling dizzy 1
Extrapyramidal symptoms 1
frequent urination 1
nasal congestion 1
feeling tired 1
acute pain 1
chest tightness 1
generalised tiredness 1
Breast tenderness 1
shoulder pain 1
wheezing 1
cancer pain 1
hypothermia 1
urinary frequency 1
dry skin 1
Welt 1
photopsia 1
photophobia 1
low back pain 1
muscle rigidity 1
sneezing 1
Breast discomfort 1
epigastric pain 1
spasm 1
syncope 1
Poor sleep 1
Drug
Zoladex 15
Zoladex 12
Estrogens 12
MAP 12
Raloxifene 11
Gabapentin 11
Tibolone 10
EE2 10
ICI 8
Encore 8
Clonidine 8
Premarin 8
vitamin E 8
Fulvestrant 7
Casodex 7
Arimidex 5
DMAP 4
Luteinizing 4
Cetrorelix 3
Lupron 3
Femara 3
Nephron 3
Depo-Provera 3
caffeine 2
Moclobemide 2
Vorozole 2
Monit 2
Vitamin E 2
Cetrotide 2
Mirtazapine 2
CTX 2
ascorbate 2
RAL 2
Dermatol 2
Glycyrrhiza 2
Estriol 2
Bazedoxifene acetate 2
Domperidone 2
Evista 2
Sulpiride 1
Fluorescein 1
Aromasin 1
Ethamsylate 1
Epidoxorubicin 1
Kenyan 1
Check 1
Norplant 1
Idoxifene 1
HCG 1
CTX 1
DMSA 1
MRC 1
ROC 1
Levonorgestrel 1
TAK 1
Xanthium 1
Naprosyn 1
Duloxetine 1
Tianma 1
Cardiovasc 1
Clomiphene citrate 1
Triptorelin 1
OTC 1
Vitamin B12 1
Spectrum 1
OTC 1
CTX 1
Aliskiren 1
Drospirenone 1
Didrogesterone 1
CAM 1
Fluorescein 1
cetrorelix acetate 1
Ginseng 1
Herceptin 1
Reboxetine 1
niacin 1
TAT 1
Trimegestone 1
NAG 1
Soybean oil 1
Tramal 1
Enzyme
alkaline phosphatase 13
prostate-specific antigen 10
alanine aminotransferase 6
renin 4
gamma-glutamyl transpeptidase 2
ERK 2
monoamine oxidase 2
ornithine transcarbamylase 1
aspartate aminotransferase 1
EPT 1
TOR 1
luciferase 1
PRA 1
CYP3A4 1
acetylcholinesterase 1
TAT 1
CPT 1
superoxide dismutase 1
focal adhesion kinase 1
acid phosphatase 1
catalase 1
GSK 1
thrombin 1
Compound
Clin 114
Dec 111
acetate 80
Estrogen 53
Estrogen 47
calcium 40
Tamoxifen 36
Tamoxifen 35
glucose 17
Estradiol 14
noradrenaline 14
creatinine 11
Raloxifene 11
5-HT 11
Progesterone 10
Androgen 9
MAP 9
Anastrozole 8
Premarin 8
Premarin 8
ICI 8
sulfate 8
Testosterone 7
Exemestane 7
Testosterone 7
sodium 6
Paroxetine 6
Nafarelin 6
vitamin D 6
aldosterone 6
Letrozole 6
DHA 5
water 5
MPA 5
CO2 5
MPA 5
MPA 5
Cyproterone acetate 5
GABA 4
Venlafaxine 4
TSH 4
DSM 4
piperazine 4
Gly 4
GABA 4
phosphate 4
DMAP 4
BMD 4
Cortisol 3
TTS 3
gamma-aminobutyric acid 3
Androstenedione 3
ethanol 3
RU-486 3
Danazol 3
GPT 3
benzamide 3
Calcitonin 3
tryptophan 3
CAM 2
TRH 2
Cardiol 2
ACTH 2
Estriol 2
Colprone 2
Bicalutamide 2
urea 2
Norepinephrine 2
salt 2
Medroxyprogesterone 2
TTP 2
Vitamin E 2
Risperidone 2
strontium 2
caffeine 2
prostacyclin 2
oxygen 2
PMS 2
Equol 2
Norethisterone 2
FTA 2
Toremifene 2
tryptophan 2
Trazodone 2
Mirtazapine 2
NH2 2
alanine 2
Ritodrine 1
DBP 1
MGA 1
serine 1
Chlorogenic acid 1
Dexamethasone 1
Luteolin 1
iron 1
Resveratrol 1
DBP 1
Morphine 1
LPR 1
methylhistamine 1
Droloxifene 1
CTX 1
Pregnane 1
glutamate 1
A 42 1
ALP 1
tryptophan 1
coenzyme Q10 1
Buspirone 1
Naloxone 1
nitrogen 1
homocysteine 1
Levcromakalim 1
Elan 1
PEP 1
Insulin 1
hyaluronic acid 1
selenium 1
Opipramol 1
CES 1
Diltiazem 1
DAD 1
Norgestrel 1
Diltiazem 1
kaempferol 1
VM-26 1
methanol 1
PPD 1
5-hydroxytryptophan 1
Genistein 1
THP 1
Hemoglobin 1
tryptophan 1
iodine 1
Primatol 1
Geigy 1
EAA 1
BRL 1
Nystatin 1
THP 1
PPD 1
Levonorgestrel 1
Primatol 1
His 1
Cholesterol 1
Diazepam 1
ASA 1
MCH 1
hydroxyindoleacetic acid 1
Tramadol 1
Coenzyme Q10 1
Sertraline 1
Aminoglutethimide 1
galactose 1
Optimal 1
Thyroid 1
ADP-ribose 1
beta-alanine 1
4-OH-A 1
CPP 1
FBF 1
DES 1
EDS 1
potassium 1
Isoflavone 1
Curcumin 1
Heparin 1
MDA 1
CPP 1
indane 1
GMP 1
Tranexamic acid 1
Citalopram 1
succinic acid 1
DNA 1
ACh 1
Nystatin 1
Yohimbine 1
Primatol 1
DFS 1
Cereb 1
Organon 1
Cilag 1
copper 1
Dolasetron 1
CAP 1
HCO 1
zinc 1
nitric oxide 1
Sumatriptan 1
Bupropion 1
Estrone 1
Amiodarone 1
Nifedipine 1
Elan 1
Domperidone 1
hexane 1
Clomiphene 1
Dydrogesterone 1
TNF 1
dichloromethane 1
2,3-dinor-thromboxane 1
TEM 1
BMC 1