Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0600142 (
hot flushes
)
1,242
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
estrogen receptor
77
Sep
70
FSH
60
aromatase
50
LHRH
33
follicle-stimulating hormone
32
prolactin
22
oestrogen receptor
15
hormone receptor
14
Mol
14
alkaline phosphatase
13
HDL
12
neurokinin B
12
progesterone receptor
11
insulin
11
prostate-specific antigen
10
Hop
9
CYP2D6
9
kisspeptin
9
Men
8
sex hormone-binding globulin
8
osteocalcin
8
beta-endorphin
7
PRL
7
calcitonin
7
NK3 receptor
6
Pol
6
cytochrome P450
6
She
5
C30
5
dynorphin
4
Prolactin
4
GnRH receptor
4
Ki-67
4
BMD
4
FACT
4
estrogen receptor alpha
4
ATAC
4
renin
4
GABA
4
more...
Disease
breast cancer
277
osteoporosis
136
depression
129
cancer
128
prostate cancer
85
cardiovascular disease
55
amenorrhea
49
endometriosis
43
uterus
39
endometrial cancer
38
sleep disturbances
35
tumor
33
endometrial hyperplasia
31
carcinoma
27
vaginal atrophy
26
gynecomastia
24
hypertension
23
sexual dysfunction
22
stroke
20
metastases
19
infertility
17
vaginal discharge
15
xerostomia
15
diabetes
14
metastatic breast cancer
13
Alzheimer's disease
13
pruritus
13
premenstrual syndrome
12
hypogonadism
12
uterine leiomyoma
12
anemia
11
impotence
11
menopausal syndrome
11
ovarian cancer
10
cold
10
incontinence
10
myocardial infarction
9
vagina
9
leiomyoma
9
heart disease
8
more...
Symptom
hot flushes
1242
hot flashes
317
menopausal symptoms
185
night sweats
95
headache
86
fatigue
83
pain
74
insomnia
68
nausea
56
flushing
42
discomfort
31
dizziness
28
discomfort
28
arthralgia
25
vomiting
18
diarrhea
16
sleepiness
13
excessive sweating
12
leg cramps
12
nausea and vomiting
11
myalgia
11
chills
10
Vaginal dryness
10
mastalgia
10
erythema
9
anorexia
8
peri-menopausal
8
pelvic pain
8
abdominal pain
7
Climacteric symptoms
7
exhaustion
7
back pain
7
paresthesia
6
dyspnea
6
asthenia
6
seizures
6
numbness
6
forgetfulness
5
tremor
5
lassitude
5
more...
Drug
Zoladex
15
Estrogens
12
Zoladex
12
MAP
12
Raloxifene
11
Gabapentin
11
EE2
10
Tibolone
10
ICI
8
Premarin
8
Encore
8
vitamin E
8
Clonidine
8
Casodex
7
Fulvestrant
7
Arimidex
5
DMAP
4
Luteinizing
4
Depo-Provera
3
Lupron
3
Femara
3
Cetrorelix
3
Nephron
3
caffeine
2
ascorbate
2
RAL
2
Moclobemide
2
Dermatol
2
Bazedoxifene acetate
2
Mirtazapine
2
Estriol
2
Vitamin E
2
Glycyrrhiza
2
Cetrotide
2
Vorozole
2
Monit
2
CTX
2
Domperidone
2
Evista
2
Duloxetine
1
more...
Enzyme
alkaline phosphatase
13
prostate-specific antigen
10
alanine aminotransferase
6
renin
4
gamma-glutamyl transpeptidase
2
ERK
2
monoamine oxidase
2
ornithine transcarbamylase
1
aspartate aminotransferase
1
EPT
1
TOR
1
luciferase
1
PRA
1
CYP3A4
1
acetylcholinesterase
1
TAT
1
CPT
1
superoxide dismutase
1
focal adhesion kinase
1
acid phosphatase
1
catalase
1
GSK
1
thrombin
1
Compound
Clin
114
Dec
111
acetate
80
Estrogen
53
Estrogen
47
calcium
40
Tamoxifen
36
Tamoxifen
35
glucose
17
Estradiol
14
noradrenaline
14
5-HT
11
creatinine
11
Raloxifene
11
Progesterone
10
Androgen
9
MAP
9
Anastrozole
8
Premarin
8
sulfate
8
Premarin
8
ICI
8
Testosterone
7
Exemestane
7
Testosterone
7
vitamin D
6
Paroxetine
6
aldosterone
6
Letrozole
6
Nafarelin
6
sodium
6
DHA
5
MPA
5
MPA
5
MPA
5
Cyproterone acetate
5
CO2
5
water
5
TSH
4
DSM
4
more...