Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0600142 (hot flushes)
 1,242 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
estrogen receptor 77
Sep 70
FSH 60
aromatase 50
LHRH 33
follicle-stimulating hormone 32
prolactin 22
oestrogen receptor 15
hormone receptor 14
Mol 14
alkaline phosphatase 13
neurokinin B 12
HDL 12
insulin 11
progesterone receptor 11
prostate-specific antigen 10
Hop 9
CYP2D6 9
kisspeptin 9
sex hormone-binding globulin 8
Men 8
osteocalcin 8
PRL 7
beta-endorphin 7
calcitonin 7
cytochrome P450 6
NK3 receptor 6
Pol 6
C30 5
She 5
Ki-67 4
BMD 4
ATAC 4
GABA 4
estrogen receptor alpha 4
GnRH receptor 4
dynorphin 4
renin 4
FACT 4
Prolactin 4
Calcitonin 3
WHI 3
reserved 3
delta 4 3
epidermal growth factor receptor 3
CYP 3
GPT 3
CEE 3
Aromatase 3
prothrombin 3
CO2 3
hemoglobin 3
corticotropin-releasing factor 2
adrenocorticotropic hormone 2
HER2 2
parathyroid hormone 2
growth hormone 2
cage 2
ACTH 2
PSA 2
CBT 2
ANOVA 2
CBG 2
androgen receptor 2
AVP 2
TTP 2
sex hormone binding globulin 2
thyroxine-binding globulin 2
CS2 2
antithrombin III 2
MRS 2
enigma 2
fibrinogen 2
collagen 2
apolipoprotein B 2
cytochrome P450 2D6 2
IVF 2
short form 2
CDS 2
NK3R 2
TRH 2
Gen 2
Neurokinin B 2
ESX 2
PMS 2
NCF 2
vascular endothelial growth factor 2
L17 1
NKB 1
visfatin 1
4E-BP1 1
VHL 1
reductase 1
catechol-O-methyltransferase 1
MOS 1
period 2 1
DBP 1
TOR 1
Bak 1
ESR2 1
NAG 1
CYP3A4 1
angiotensinogen 1
DHEAS 1
elastin 1
proliferating cell nuclear antigen 1
angiotensin II 1
EPT 1
synaptophysin 1
period 3 1
PSS 1
amyloid precursor protein 1
BIG1 1
albumin 1
neu 1
acid phosphatase 1
A-I 1
HCG 1
calcium channel 1
caspase 7 1
NHS 1
STAR 1
GDS 1
GCS 1
spermatozoa 1
thyrotropin-releasing hormone 1
Sex hormone-binding globulin 1
mammaglobin 1
5-HT1B 1
TAK 1
TNF 1
caspase-9 1
corticosteroid binding globulin 1
leptin 1
thrombin 1
cytochrome 1
CRF 1
MGA 1
adrenomedullin 1
apoE 1
prostatic acid phosphatase 1
nuclear receptor 1
calmodulin 1
sclerostin 1
IGF-1 1
aryl hydrocarbon receptor 1
Estrogen receptor 1 1
HTR 1
long chain 1
MRI 1
MAO-A 1
Orexin 1
superoxide dismutase 1
DES 1
RAD 1
GPR54 1
transporter 1 1
melanin-concentrating hormone 1
sterol regulatory element-binding protein-1c 1
catenin 1
organic anion transporting polypeptide 1
galanin 1
GMP 1
HTX 1
vesicular glutamate transporter 2 1
GRP78 1
alpha 1-antitrypsin 1
chromogranin A 1
BRL 1
CTB 1
Ang II 1
proopiomelanocortin 1
apolipoprotein 1
SBP 1
CD56 1
c-fos 1
endothelin-1 1
CYP3A 1
platelet-derived growth factor 1
neurotensin 1
HSP70 1
mineralocorticoid receptor 1
tyrosine kinase 1
duo 1
orexin 1
TGF-beta 1
eukaryotic translation initiation factor 4E 1
anonymous 1
GATA3 1
glycodelin 1
NALP3 1
cholecystokinin 1
JAMA 1
WIN 1
PRA 1
LHbeta 1
TTK 1
OTC 1
CTX 1
mTOR 1
nerve growth factor 1
glucagon 1
ISA 1
caspase-3 1
STD 1
VIP 1
adipokine 1
PEP 1
carcinoembryonic antigen 1
MIB 1
REM 1
gut 1
Intermedin 1
CAS 1
ER beta 1
STH 1
GAF 1
FACE 1
SPA 1
gp17 1
CYP2B6 1
ALP 1
carnitine palmitoyltransferase 1
MRC 1
TTR 1
BRI 1
fatty acid synthase 1
Bcl-2 1
TAT 1
ICD 1
AMH 1
ASL 1
ASA 1
GTT 1
GRP 1
Cytochrome P450 1
THP 1
CCK-4 1
interferon 1
SULT1E1 1
acetylcholinesterase 1
catalase 1
CYP2C19 1
cytokine 1
glutamate pyruvate transaminase 1
CD105 1
monocyte chemoattractant protein-1 1
5-HT2A 1
nodal 1
PHS 1
cytokeratin 1
NOT 1
tumor necrosis factor 1
EDRF 1
osteogenic 1
Sclerostin 1
HSP72 1
CAM 1
bone morphogenetic protein 1
EPO 1
rhodanese 1
Leydig cell 1
transforming growth factor-beta 1 1
5-HT1A 1
IGFBP3 1
PAIS 1
version 3 1
osteosarcoma 1
PPD 1
TRP 1
EMA 1
ARH 1
CAF 1
Disease
breast cancer 277
osteoporosis 136
depression 129
cancer 128
prostate cancer 85
cardiovascular disease 55
amenorrhea 49
endometriosis 43
uterus 39
endometrial cancer 38
sleep disturbances 35
tumor 33
endometrial hyperplasia 31
carcinoma 27
vaginal atrophy 26
gynecomastia 24
hypertension 23
sexual dysfunction 22
stroke 20
metastases 19
infertility 17
vaginal discharge 15
xerostomia 15
diabetes 14
metastatic breast cancer 13
Alzheimer's disease 13
pruritus 13
hypogonadism 12
uterine leiomyoma 12
premenstrual syndrome 12
anemia 11
impotence 11
menopausal syndrome 11
incontinence 10
cold 10
ovarian cancer 10
vagina 9
leiomyoma 9
myocardial infarction 9
Best 8
migraine 8
emotional instability 8
Prostate Cancer 8
heart disease 8
obesity 7
erectile dysfunction 7
recurrent breast cancer 7
major depressive disorder 7
sleep disorders 7
coronary artery disease 7
cognitive impairment 7
atherosclerosis 7
coronary heart disease 7
postmenopausal bone loss 7
epilepsy 6
dementia 6
uterine cancer 6
atrophic vaginitis 6
rash 6
ovarian cysts 6
metabolic syndrome 6
deep vein thrombosis 6
incontinence 5
dyspepsia 5
mental illness 5
pulmonary embolism 5
precocious puberty 5
West 5
acne 5
hypercholesterolemia 5
cervical cancer 5
panic disorder 5
myoma 5
premature menopause 5
premature ovarian failure 5
type 2 diabetes 4
myelosuppression 4
Pituitary 4
BMD 4
psychological distress 4
hyperprolactinemia 4
tumor growth 4
galactorrhea 4
anxiety disorders 4
galactorrhea 4
adenocarcinoma 4
secondary amenorrhea 4
confusion 4
MCF 4
clinical depression 4
dysphoria 3
abortion 3
lymphedema 3
endometrial adenocarcinoma 3
SEM 3
hyperandrogenism 3
panic attacks 3
stress incontinence 3
leukopenia 3
seborrheic dermatitis 3
myocardial ischemia 3
melancholia 3
essential hypertension 3
polycystic ovary syndrome 3
Vulvovaginal atrophy 3
carcinoid 3
postherpetic neuralgia 3
Parkinson's disease 3
thrombophlebitis 3
postpartum depression 3
cystitis 3
emotional distress 3
hallucinations 3
heart failure 2
tumor progression 2
AIDS 2
Steroids 2
Still 2
arthritis 2
renal impairment 2
TTP 2
neuroticism 2
STD 2
osteoporotic fracture 2
suicide 2
prostatic adenocarcinoma 2
PSA 2
fibromyalgia 2
ductal carcinoma in situ 2
prolapse 2
bone metastases 2
vaginal infection 2
gallstones 2
Estrogen deficiency 2
peripheral neuropathy 2
hyperlipidemia 2
MRS 2
premature labor 2
vaginal candidiasis 2
malnutrition 2
dyslipidemia 2
chronic disease 2
HIV 2
meningioma 2
paroxysmal supraventricular tachycardia 2
hypercalcemia 2
IVF 2
plaque 2
hyperthyroidism 2
PMS 2
testicular cancer 2
bipolar disorder 2
primary tumor 2
premenstrual dysphoric disorder 2
dyskinesia 2
Dependence 2
epithelial ovarian cancer 2
thrombocytopenia 2
Hodgkin's disease 2
TTP 2
colon cancer 2
cardiovascular risk factor 2
CDS 2
Ovary 2
carcinoma of the breast 2
hypoglycemia 2
social stress 2
fits 2
hypomenorrhea 1
Adhesion 1
prostatic disease 1
renal disease 1
toxoplasmosis 1
hyperglycemia 1
gestational trophoblastic disease 1
posttraumatic stress disorder 1
pheochromocytoma 1
renal cyst 1
craniopharyngioma 1
trisomy 1
psychological stress 1
congestive heart failure 1
adjustment disorder 1
muscular atrophy 1
dermoid cyst 1
Muckle-Wells syndrome 1
seminoma 1
pathological personality 1
Pelvic endometriosis 1
carcinoid syndrome 1
psychoactive substance abuse 1
Prinzmetal 1
derealization 1
psychosomatic disorders 1
myelofibrosis 1
Gallbladder disease 1
endocrine disorder 1
Autoimmune oophoritis 1
bends 1
Rust 1
psychosis 1
delayed puberty 1
chronic obstructive pulmonary disease 1
FBD 1
Sheehan's syndrome 1
Wells 1
pulmonary edema 1
emphysema 1
fibrocystic breast disease 1
illusion 1
syphilis 1
acute leukemia 1
Pseudopregnancy 1
immunodeficiency 1
hepatitis 1
Pelvic inflammatory disease 1
Sleep disturbance 1
learning disability 1
lupus 1
upper respiratory infection 1
PSS 1
psychiatric diagnosis 1
urinary system cancer 1
osteosarcoma 1
neutropenia 1
fibromatosis 1
carcinoma of the breast 1
HTX 1
delirium 1
agranulocytosis 1
fallopian tube 1
demineralization of bone 1
urethra 1
systemic lupus erythematosus 1
thyroid cancer 1
PHS 1
Male hypogonadism 1
bladder cancer 1
urethritis 1
lung cancer 1
oligospermia 1
ileus 1
Lyme disease 1
Central precocious puberty 1
Merkel cell carcinoma 1
pelvic inflammatory disease 1
HTX 1
periodontal disease 1
drunk 1
warts 1
seminal vesicles 1
fear of cancer 1
renal cell carcinoma 1
urticaria 1
rosacea 1
myasthenia 1
NHS 1
Hippel 1
parkinsonism 1
Endometrial atrophy 1
GAD 1
chronic renal failure 1
major depressive episode 1
bone disease 1
phlebitis 1
Female sexual dysfunction 1
Schistosoma mansoni infection 1
tumorigenesis 1
oophoritis 1
bronchitis 1
carpal tunnel syndrome 1
endometrial stromal sarcoma 1
dyschromia 1
fatty liver 1
mastopathy 1
unipolar depression 1
Withdrawal bleeding 1
intermittent claudication 1
sleep apnea 1
ICD 1
neurotic depression 1
lung disease 1
flutter 1
vaginitis 1
carcinogenesis 1
Down syndrome 1
pemphigoid 1
Thymus 1
CHH 1
varices 1
liver disease 1
acute pancreatitis 1
polycythemia vera 1
lichen planus 1
CAM 1
vascular disease 1
diabetic neuropathy 1
vascular headache 1
Jensen 1
porphyria 1
pulmonary fibrosis 1
glucose intolerance 1
aggressiveness 1
venous insufficiency 1
Thymus 1
lipid disorder 1
cystic fibrosis 1
bronchitis 1
CES 1
hormone deficiency 1
gonadal dysgenesis 1
amyotrophic lateral sclerosis 1
HCG 1
disorientation 1
transient ischemic attack 1
regional pain syndrome 1
Dubin-Johnson syndrome 1
spinal cord compression 1
hypoactive sexual desire disorder 1
gonococcal 1
more...
Symptom
hot flushes 1242
hot flashes 317
menopausal symptoms 185
night sweats 95
headache 86
fatigue 83
pain 74
insomnia 68
nausea 56
flushing 42
discomfort 31
discomfort 28
dizziness 28
arthralgia 25
vomiting 18
diarrhea 16
sleepiness 13
leg cramps 12
excessive sweating 12
myalgia 11
nausea and vomiting 11
Vaginal dryness 10
chills 10
mastalgia 10
erythema 9
anorexia 8
pelvic pain 8
peri-menopausal 8
Climacteric symptoms 7
back pain 7
abdominal pain 7
exhaustion 7
dyspnea 6
paresthesia 6
asthenia 6
seizures 6
numbness 6
vertigo 5
Crawling 5
forgetfulness 5
tremor 5
lassitude 5
weakness 4
overweight 4
Breast pain 4
bone pain 4
constipation 4
skin irritation 4
Ill 3
anesthesia 3
leg edema 3
thinning 3
chest pain 3
lethargy 3
bloating 3
cough 3
limb pain 3
memory loss 2
shortness of breath 2
dysuria 2
ataxia 2
menometrorrhagia 2
tingling 2
collapse 2
masculinization 2
hoarseness 2
cold sweats 2
agitation 2
abdominal cramps 2
apathy 2
irregular bleeding 2
stomach pain 2
tense 2
angina 2
nipple discharge 1
tinnitus 1
rhinorrhea 1
despair 1
Spotting 1
feeling depressed 1
hopelessness 1
Fatigability 1
hypersomnia 1
bitter taste 1
bewilderment 1
blurred vision 1
abdominal fullness 1
mental fatigue 1
respiratory distress 1
Wind 1
analgesia 1
feeling dizzy 1
Extrapyramidal symptoms 1
frequent urination 1
nasal congestion 1
feeling tired 1
acute pain 1
chest tightness 1
generalised tiredness 1
Breast tenderness 1
shoulder pain 1
wheezing 1
cancer pain 1
hypothermia 1
urinary frequency 1
dry skin 1
Welt 1
photopsia 1
photophobia 1
low back pain 1
muscle rigidity 1
sneezing 1
Breast discomfort 1
epigastric pain 1
spasm 1
syncope 1
Poor sleep 1
Drug
Zoladex 15
Zoladex 12
Estrogens 12
MAP 12
Raloxifene 11
Gabapentin 11
Tibolone 10
EE2 10
ICI 8
Encore 8
Clonidine 8
Premarin 8
vitamin E 8
Fulvestrant 7
Casodex 7
Arimidex 5
DMAP 4
Luteinizing 4
Cetrorelix 3
Lupron 3
Femara 3
Nephron 3
Depo-Provera 3
caffeine 2
Moclobemide 2
Vorozole 2
Monit 2
Vitamin E 2
Cetrotide 2
Mirtazapine 2
CTX 2
ascorbate 2
RAL 2
Dermatol 2
Glycyrrhiza 2
Estriol 2
Bazedoxifene acetate 2
Domperidone 2
Evista 2
Sulpiride 1
Fluorescein 1
Aromasin 1
Ethamsylate 1
Epidoxorubicin 1
Kenyan 1
Check 1
Norplant 1
Idoxifene 1
HCG 1
CTX 1
DMSA 1
MRC 1
ROC 1
Levonorgestrel 1
TAK 1
Xanthium 1
Naprosyn 1
Duloxetine 1
Tianma 1
Cardiovasc 1
Clomiphene citrate 1
Triptorelin 1
OTC 1
Vitamin B12 1
Spectrum 1
OTC 1
CTX 1
Aliskiren 1
Drospirenone 1
Didrogesterone 1
CAM 1
Fluorescein 1
cetrorelix acetate 1
Ginseng 1
Herceptin 1
Reboxetine 1
niacin 1
TAT 1
Trimegestone 1
NAG 1
Soybean oil 1
Tramal 1
Enzyme
alkaline phosphatase 13
prostate-specific antigen 10
alanine aminotransferase 6
renin 4
gamma-glutamyl transpeptidase 2
ERK 2
monoamine oxidase 2
ornithine transcarbamylase 1
aspartate aminotransferase 1
EPT 1
TOR 1
luciferase 1
PRA 1
CYP3A4 1
acetylcholinesterase 1
TAT 1
CPT 1
superoxide dismutase 1
focal adhesion kinase 1
acid phosphatase 1
catalase 1
GSK 1
thrombin 1
Compound
Clin 114
Dec 111
acetate 80
Estrogen 53
Estrogen 47
calcium 40
Tamoxifen 36
Tamoxifen 35
glucose 17
Estradiol 14
noradrenaline 14
creatinine 11
Raloxifene 11
5-HT 11
Progesterone 10
Androgen 9
MAP 9
Anastrozole 8
Premarin 8
Premarin 8
ICI 8
sulfate 8
Testosterone 7
Exemestane 7
Testosterone 7
sodium 6
Paroxetine 6
Nafarelin 6
vitamin D 6
aldosterone 6
Letrozole 6
DHA 5
water 5
MPA 5
CO2 5
MPA 5
MPA 5
Cyproterone acetate 5
GABA 4
Venlafaxine 4
TSH 4
DSM 4
piperazine 4
Gly 4
GABA 4
phosphate 4
DMAP 4
BMD 4
Cortisol 3
TTS 3
gamma-aminobutyric acid 3
Androstenedione 3
ethanol 3
RU-486 3
Danazol 3
GPT 3
benzamide 3
Calcitonin 3
tryptophan 3
CAM 2
TRH 2
Cardiol 2
ACTH 2
Estriol 2
Colprone 2
Bicalutamide 2
urea 2
Norepinephrine 2
salt 2
Medroxyprogesterone 2
TTP 2
Vitamin E 2
Risperidone 2
strontium 2
caffeine 2
prostacyclin 2
oxygen 2
PMS 2
Equol 2
Norethisterone 2
FTA 2
Toremifene 2
tryptophan 2
Trazodone 2
Mirtazapine 2
NH2 2
alanine 2
Ritodrine 1
DBP 1
MGA 1
serine 1
Chlorogenic acid 1
Dexamethasone 1
Luteolin 1
iron 1
Resveratrol 1
DBP 1
Morphine 1
LPR 1
methylhistamine 1
Droloxifene 1
CTX 1
Pregnane 1
glutamate 1
A 42 1
ALP 1
tryptophan 1
coenzyme Q10 1
Buspirone 1
Naloxone 1
nitrogen 1
homocysteine 1
Levcromakalim 1
Elan 1
PEP 1
Insulin 1
hyaluronic acid 1
selenium 1
Opipramol 1
CES 1
Diltiazem 1
DAD 1
Norgestrel 1
Diltiazem 1
kaempferol 1
VM-26 1
methanol 1
PPD 1
5-hydroxytryptophan 1
Genistein 1
THP 1
Hemoglobin 1
tryptophan 1
iodine 1
Primatol 1
Geigy 1
EAA 1
BRL 1
Nystatin 1
THP 1
PPD 1
Levonorgestrel 1
Primatol 1
His 1
Cholesterol 1
Diazepam 1
ASA 1
MCH 1
hydroxyindoleacetic acid 1
Tramadol 1
Coenzyme Q10 1
Sertraline 1
Aminoglutethimide 1
galactose 1
Optimal 1
Thyroid 1
ADP-ribose 1
beta-alanine 1
4-OH-A 1
CPP 1
FBF 1
DES 1
EDS 1
potassium 1
Isoflavone 1
Curcumin 1
Heparin 1
MDA 1
CPP 1
indane 1
GMP 1
Tranexamic acid 1
Citalopram 1
succinic acid 1
DNA 1
ACh 1
Nystatin 1
Yohimbine 1
Primatol 1
DFS 1
Cereb 1
Organon 1
Cilag 1
copper 1
Dolasetron 1
CAP 1
HCO 1
zinc 1
nitric oxide 1
Sumatriptan 1
Bupropion 1
Estrone 1
Amiodarone 1
Nifedipine 1
Elan 1
Domperidone 1
hexane 1
Clomiphene 1
Dydrogesterone 1
TNF 1
dichloromethane 1
2,3-dinor-thromboxane 1
TEM 1
BMC 1