Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0600142 (
hot flushes
)
1,242
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The effect of a menopausal
hot flush
on respiratory parameters was studied in one subject on nine separate occasions. The flushes were associated with a significant increase in the production of carbon dioxide and lesser but still significant changes in
oxygen
consumption, tidal volume and minute volume. The changes in respiratory frequency and respiratory quotient were not significant. Significant changes in carbon dioxide production and
oxygen
consumption were still evident well into the climacteric.
...
PMID:Respiratory changes during a menopausal hot flush. 313 66
Effects of estrogen on thermoregulatory vasomotion and heat-escape behavior were investigated in ovariectomized female rats supplemented with estrogen (replaced estrogen rats) or control saline (low estrogen rats). First, we measured tail temperature of freely moving rats at ambient temperatures (T(a)) between 13 and 31 degrees C. Tail temperature of the low estrogen rats was higher than that of the replaced estrogen rats at T(a) between 19 and 25 degrees C, indicating that the low estrogen rats exhibit more skin vasodilation than the replaced estrogen rats. There was no significant difference in
oxygen
consumption and core temperature between the two groups. Second, we analyzed heat-escape behaviors in a hot chamber where rats could obtain cold air by moving in and out of a reward area. The low estrogen rats kept T(a) at a lower level than did the replaced estrogen rats. These results imply that the lack of estrogen facilitates heat dissipation both by skin vasodilation and by heat-escape behavior. Ovariectomized rats may mimic climacteric
hot flushes
not only for autonomic skin vasomotor activity but also for thermoregulatory behavior.
...
PMID:Effects of estrogen on thermoregulatory tail vasomotion and heat-escape behavior in freely moving female rats. 1129 52