Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0599766 (functional recovery)
 13,441 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Clinical data of 31 patients (34 renal units) with severe congenital hydronephrosis who had received preliminary nephrostomy were reviewed to survey functional recovery of the kidneys and the significance of preliminary nephrostomy. The results were as follows: 1. In most cases, the renal function based on Ccr and 99mTc-DMSA renal scintigraphy after nephrostomy could not improve beyond preoperative one. 2. A close linear correction was found between the thickness of renal parenchyma before preliminary nephrostomy and the renal function after the nephrostomy. 3. Preliminary nephrostomy is indicated for severe hydronephrosis in neonates and infants, obstruction of the lower ureter, and serious general condition, which need accurate split renal function, and for patients without accurate diagnosis.
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PMID:[Clinical research on congenital hydronephrosis--significance and indication of the preliminary nephrostomy]. 262 26

The renal handling of dimercaptosuccinic acid and hippuran differs. This might be used in unilateral obstructive nephropathy in order to predict potential functional recovery following intervention. The theory was evaluated on a retrospective basis in 17 patients, who primarily had a nephrostomy. If the DMSA-uptake rate in the diseased kidney was more than 10 per cent higher than that of hippuran, the uptake rate of hippuran increased following relief of obstruction. Use of the two radiopharmaceuticals, thus, may have great impact on the clinical decision, since in case of a difference some function may be saved by immediate intervention.
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PMID:Combination of DMSA-scintigraphy and hippuran renography in unilateral obstructive nephropathy. Improved prediction of recovery after intervention. 282 57