Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0598934 (
tumor growth
)
58,965
document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Mol
4544
Sep
3511
vascular endothelial growth factor
2311
p53
2079
cytokine
1829
AKT
1685
CD8
1568
caspase-3
1455
VEGF
1365
mTOR
1317
Bcl-2
1162
PI3K
1140
epidermal growth factor receptor
969
CD4
935
tyrosine kinase
927
cage
923
ERK
912
catenin
857
IFN
843
p21
815
tumor necrosis factor
791
STAT3
783
MAPK
775
cyclin D1
754
interferon
665
EGFR
664
IL-6
664
estrogen receptor
644
collagen
637
osteosarcoma
627
E-cadherin
621
TNF
618
ATP
587
CD44
573
ERK1
572
matrix metalloproteinase
569
chemokine
561
PEG
557
colon carcinoma
545
HER2
534
VEGFR2
527
PARP
525
MMP-9
501
CD31
500
Ki-67
497
lymphoid
485
ACS
468
IL-2
467
IFN-gamma
458
p38
445
insulin
434
PC-3
431
MEK
430
receptor tyrosine kinase
423
c-Myc
415
MMP-2
407
survivin
402
IL-10
397
PD-1
394
PTEN
391
ROS
390
endoplasmic reticulum
385
PD-L1
385
proliferating cell nuclear antigen
384
proteasome
384
fibronectin
376
MRI
376
UTR
367
histone
361
Vascular endothelial growth factor
361
p27
358
androgen receptor
346
IL-8
341
caspase-9
340
JNK
336
epidermal growth factor
335
BRAF
330
PC3
323
endostatin
316
COX-2
307
more...
Disease
tumor growth
58965
tumor
41526
cancer
32490
breast cancer
5661
tumor progression
4431
carcinoma
3881
tumorigenesis
3757
melanoma
3660
metastases
3340
hepatocellular carcinoma
2745
prostate cancer
2340
lung cancer
2264
adenocarcinoma
2248
carcinogenesis
1918
colorectal cancer
1826
glioma
1756
tumor angiogenesis
1694
colon cancer
1517
pancreatic cancer
1366
squamous cell carcinoma
1293
glioblastoma
1266
MCF
1223
ovarian cancer
1174
lung carcinoma
1106
non-small cell lung cancer
1093
gastric cancer
1067
primary tumor
1043
sarcoma
891
leukemia
870
SCID
849
lymphoma
784
solid tumor
724
renal cell carcinoma
710
osteosarcoma
699
mammary tumor
677
liver cancer
667
fibrosarcoma
647
brain tumor
612
neuroblastoma
605
multiple myeloma
601
tumor vasculature
570
aggressiveness
550
cervical cancer
524
bladder cancer
519
liver cancer
516
lung metastases
504
glioblastoma multiforme
457
epithelial ovarian cancer
447
Hepatocellular carcinoma
384
tumor initiation
353
B-cell lymphoma
322
NOD
282
Melanoma
274
Glioblastoma
267
acute myeloid leukemia
261
retinoblastoma
255
herpes simplex
253
metastatic breast cancer
245
metastatic melanoma
241
obesity
239
EMT
231
endometrial cancer
229
diabetes
227
liver metastases
224
Blocking
222
GSH
207
esophageal cancer
206
DDP
197
skin cancer
182
esophageal cancer
181
thyroid cancer
181
bone metastases
179
adenoma
177
renal cancer
176
suicide
176
head and neck cancer
172
medulloblastoma
168
DBA
165
AS1
164
rhabdomyosarcoma
159
more...
Symptom
cachexia
257
pain
248
starvation
174
anorexia
102
exhaustion
95
diarrhea
79
collapse
76
fatigue
67
splenomegaly
63
anesthesia
61
seizures
54
acidity
54
headache
52
nausea
44
bone pain
43
cancer pain
40
vomiting
33
abdominal pain
29
weakness
29
HSA
28
dyspnea
27
analgesia
24
discomfort
16
discomfort
16
thinning
16
overweight
16
erythema
15
tinnitus
14
ataxia
14
nausea and vomiting
13
hyperoxia
12
Scratch
12
flushing
12
hypothermia
12
paresis
10
numbness
10
constipation
10
cough
10
respiratory distress
9
hepatomegaly
9
hemoptysis
9
asthenia
9
skin damage
8
ENT
8
back pain
7
myalgia
7
chills
7
menopausal symptoms
6
facial pain
6
Ill
6
wheezing
6
No adverse effect
6
vertigo
5
emaciation
5
dysuria
5
ophthalmoplegia
5
hoarseness
5
paresthesia
5
flank pain
4
lethargy
4
hot flushes
4
acute stress
4
dizziness
4
hypercapnia
4
angina
4
hepatosplenomegaly
4
arthralgia
4
abdominal discomfort
3
insomnia
3
decreased appetite
3
muscle cramps
3
masculinization
3
Cushingoid
3
tense
3
neurological disability
3
syncope
3
Cushingoid
3
functional recovery
3
chest pain
3
disturbed balance
2
more...
Drug
IL-2
473
IFN-gamma
445
ROS
390
lysine
307
CSF
271
Dermatol
217
Taxol
160
Meth
158
Bevacizumab
152
CTX
133
Adriamycin
132
Sorafenib
117
Herceptin
107
Docetaxel
94
MAP
94
ADR
90
vitamin E
81
CPT-11
73
uPA
70
ascorbate
69
Monit
63
Gefitinib
62
Cetuximab
62
ADM
62
CTX
60
Bortezomib
60
CTX
58
NVP
58
Imatinib
54
GEO
53
ICI
48
TAT
48
Cardiovasc
47
G-CSF
46
IFN-beta
44
Indomethacin
43
Erlotinib
41
CAM
41
NADH
38
EE2
37
Taxotere
37
Irinotecan
34
Everolimus
32
ETS
32
Gel
29
Cremophor EL
28
Zoledronic acid
27
Photofrin
27
Vorinostat
26
ALA
25
DM1
25
Arsenic trioxide
25
Estrogens
25
Bifidobacterium
25
ABC
25
CCL
24
Heme
24
Mutagen
24
Dasatinib
24
Zoledronic acid
23
RFP
23
G418
23
Oxaliplatin
23
Gleevec
23
caffeine
22
Retinoic acid
22
Asn
22
p75
21
Norplant
20
Emodin
20
TTC
20
Angiotensin II
20
Emodin
20
TAK
18
ENT
18
Fulvestrant
18
Simvastatin
17
AMC
17
VCR
17
EPA
16
more...
Enzyme
ERK
3226
mitogen-activated protein kinase
2193
luciferase
1262
caspase-3
1128
focal adhesion kinase
962
protein kinase
765
PARP
577
MEK
563
ACS
471
proteasome
390
caspase-9
283
AMP-activated protein kinase
264
urokinase-type plasminogen activator
255
protein kinase C
223
thymidine kinase
214
phosphatidylinositol 3-kinase
213
caspase-8
201
phosphoinositide 3-kinase
196
cdc2
196
AMPK
178
P-glycoprotein
174
AMPK
162
ATPase
145
prostate-specific antigen
140
superoxide dismutase
139
APC
132
MMP
128
collagenase
127
catalase
123
GSK
121
thrombin
120
reverse transcriptase
119
lactate dehydrogenase
116
granzyme B
112
arginase
106
calcineurin
100
alanine aminotransferase
95
ornithine decarboxylase
94
plasmin
91
firefly luciferase
82
RNase
81
glutathione S-transferase
81
matrix metalloproteinase 2
81
topoisomerase
79
topoisomerase
76
aldehyde dehydrogenase
76
beta-galactosidase
76
aldehyde dehydrogenase
75
trypsin
75
peroxidase
75
cytosine deaminase
74
RNase
74
aldehyde dehydrogenase
73
aldehyde dehydrogenase
73
aldehyde dehydrogenase
73
RNA polymerase
71
thymidylate synthase
69
aspartate aminotransferase
69
alkaline phosphatase
69
PDK1
68
matrix metalloproteinase 9
66
DNA methyltransferase
65
hyaluronidase
63
NO synthase
63
cathepsin B
62
hyaluronidase
62
ALDH
59
DCF
57
IKK
57
glutathione peroxidase
57
MDR
50
demethylase
50
TAT
49
MAP
49
ribonucleotide reductase
48
polo-like kinase 1
47
complex I
46
pyruvate kinase
46
ribonucleotide reductase
45
glutaminase
44
more...
Compound
DNA
4089
Dec
3759
oxygen
2127
Clin
2007
MDA
1414
MTT
1059
PEG
937
water
917
glucose
917
tyrosine
824
PEG
692
TNF
618
ATP
587
phosphate
532
calcium
496
ACS
472
ACS
468
arginine
451
methionine
434
MEK
426
lysine
406
iron
389
serine
375
sulfate
350
nitric oxide
349
cysteine
348
sodium
327
acetate
326
DBA
304
TNM
297
bromide
291
Adriamycin
286
iodine
285
DDP
283
ADR
272
5-FU
263
zinc
243
hyaluronic acid
236
hydrogen
232
nitrogen
222
threonine
218
glutamine
218
GSH
216
retinoic acid
216
GSH
216
copper
205
anthracene
191
leucine
189
dUTP
184
galactose
182
ethanol
171
urea
166
DBA
165
DBA
165
Asp
159
cAMP
154
alanine
152
Paclitaxel
151
Phe
142
Gly
140
PGE2
140
glutamate
138
Curcumin
137
CTX
133
AMP
131
Estrogen
125
pyrimidine
122
tryptophan
121
pyrimidine
121
Estrogen
120
boron
115
His
115
selenium
114
PGE
114
SCC
114
MIA
114
BCG
112
ADP
111
NH2
108
Tamoxifen
107
more...