Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0598934 (tumor growth)
58,965 document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Mol 4544
Sep 3511
vascular endothelial growth factor 2311
p53 2079
cytokine 1829
AKT 1685
CD8 1568
caspase-3 1455
VEGF 1365
mTOR 1317
Bcl-2 1162
PI3K 1140
epidermal growth factor receptor 969
CD4 935
tyrosine kinase 927
cage 923
ERK 912
catenin 857
IFN 843
p21 815
tumor necrosis factor 791
STAT3 783
MAPK 775
cyclin D1 754
interferon 665
EGFR 664
IL-6 664
estrogen receptor 644
collagen 637
osteosarcoma 627
E-cadherin 621
TNF 618
ATP 587
CD44 573
ERK1 572
matrix metalloproteinase 569
chemokine 561
PEG 557
colon carcinoma 545
HER2 534
VEGFR2 527
PARP 525
MMP-9 501
CD31 500
Ki-67 497
lymphoid 485
ACS 468
IL-2 467
IFN-gamma 458
p38 445
insulin 434
PC-3 431
MEK 430
receptor tyrosine kinase 423
c-Myc 415
MMP-2 407
survivin 402
IL-10 397
PD-1 394
PTEN 391
ROS 390
endoplasmic reticulum 385
PD-L1 385
proliferating cell nuclear antigen 384
proteasome 384
fibronectin 376
MRI 376
UTR 367
histone 361
Vascular endothelial growth factor 361
p27 358
androgen receptor 346
IL-8 341
caspase-9 340
JNK 336
epidermal growth factor 335
BRAF 330
PC3 323
endostatin 316
COX-2 307
more...
Disease
tumor growth 58965
tumor 41526
cancer 32490
breast cancer 5661
tumor progression 4431
carcinoma 3881
tumorigenesis 3757
melanoma 3660
metastases 3340
hepatocellular carcinoma 2745
prostate cancer 2340
lung cancer 2264
adenocarcinoma 2248
carcinogenesis 1918
colorectal cancer 1826
glioma 1756
tumor angiogenesis 1694
colon cancer 1517
pancreatic cancer 1366
squamous cell carcinoma 1293
glioblastoma 1266
MCF 1223
ovarian cancer 1174
lung carcinoma 1106
non-small cell lung cancer 1093
gastric cancer 1067
primary tumor 1043
sarcoma 891
leukemia 870
SCID 849
lymphoma 784
solid tumor 724
renal cell carcinoma 710
osteosarcoma 699
mammary tumor 677
liver cancer 667
fibrosarcoma 647
brain tumor 612
neuroblastoma 605
multiple myeloma 601
tumor vasculature 570
aggressiveness 550
cervical cancer 524
bladder cancer 519
liver cancer 516
lung metastases 504
glioblastoma multiforme 457
epithelial ovarian cancer 447
Hepatocellular carcinoma 384
tumor initiation 353
B-cell lymphoma 322
NOD 282
Melanoma 274
Glioblastoma 267
acute myeloid leukemia 261
retinoblastoma 255
herpes simplex 253
metastatic breast cancer 245
metastatic melanoma 241
obesity 239
EMT 231
endometrial cancer 229
diabetes 227
liver metastases 224
Blocking 222
GSH 207
esophageal cancer 206
DDP 197
skin cancer 182
esophageal cancer 181
thyroid cancer 181
bone metastases 179
adenoma 177
renal cancer 176
suicide 176
head and neck cancer 172
medulloblastoma 168
DBA 165
AS1 164
rhabdomyosarcoma 159
more...
Symptom
cachexia 257
pain 248
starvation 174
anorexia 102
exhaustion 95
diarrhea 79
collapse 76
fatigue 67
splenomegaly 63
anesthesia 61
seizures 54
acidity 54
headache 52
nausea 44
bone pain 43
cancer pain 40
vomiting 33
abdominal pain 29
weakness 29
HSA 28
dyspnea 27
analgesia 24
discomfort 16
discomfort 16
thinning 16
overweight 16
erythema 15
tinnitus 14
ataxia 14
nausea and vomiting 13
hyperoxia 12
Scratch 12
flushing 12
hypothermia 12
paresis 10
numbness 10
constipation 10
cough 10
respiratory distress 9
hepatomegaly 9
hemoptysis 9
asthenia 9
skin damage 8
ENT 8
back pain 7
myalgia 7
chills 7
menopausal symptoms 6
facial pain 6
Ill 6
wheezing 6
No adverse effect 6
vertigo 5
emaciation 5
dysuria 5
ophthalmoplegia 5
hoarseness 5
paresthesia 5
flank pain 4
lethargy 4
hot flushes 4
acute stress 4
dizziness 4
hypercapnia 4
angina 4
hepatosplenomegaly 4
arthralgia 4
abdominal discomfort 3
insomnia 3
decreased appetite 3
muscle cramps 3
masculinization 3
Cushingoid 3
tense 3
neurological disability 3
syncope 3
Cushingoid 3
functional recovery 3
chest pain 3
disturbed balance 2
more...
Drug
IL-2 473
IFN-gamma 445
ROS 390
lysine 307
CSF 271
Dermatol 217
Taxol 160
Meth 158
Bevacizumab 152
CTX 133
Adriamycin 132
Sorafenib 117
Herceptin 107
Docetaxel 94
MAP 94
ADR 90
vitamin E 81
CPT-11 73
uPA 70
ascorbate 69
Monit 63
Gefitinib 62
Cetuximab 62
ADM 62
CTX 60
Bortezomib 60
CTX 58
NVP 58
Imatinib 54
GEO 53
ICI 48
TAT 48
Cardiovasc 47
G-CSF 46
IFN-beta 44
Indomethacin 43
Erlotinib 41
CAM 41
NADH 38
EE2 37
Taxotere 37
Irinotecan 34
Everolimus 32
ETS 32
Gel 29
Cremophor EL 28
Zoledronic acid 27
Photofrin 27
Vorinostat 26
ALA 25
DM1 25
Arsenic trioxide 25
Estrogens 25
Bifidobacterium 25
ABC 25
CCL 24
Heme 24
Mutagen 24
Dasatinib 24
Zoledronic acid 23
RFP 23
G418 23
Oxaliplatin 23
Gleevec 23
caffeine 22
Retinoic acid 22
Asn 22
p75 21
Norplant 20
Emodin 20
TTC 20
Angiotensin II 20
Emodin 20
TAK 18
ENT 18
Fulvestrant 18
Simvastatin 17
AMC 17
VCR 17
EPA 16
more...
Enzyme
ERK 3226
mitogen-activated protein kinase 2193
luciferase 1262
caspase-3 1128
focal adhesion kinase 962
protein kinase 765
PARP 577
MEK 563
ACS 471
proteasome 390
caspase-9 283
AMP-activated protein kinase 264
urokinase-type plasminogen activator 255
protein kinase C 223
thymidine kinase 214
phosphatidylinositol 3-kinase 213
caspase-8 201
phosphoinositide 3-kinase 196
cdc2 196
AMPK 178
P-glycoprotein 174
AMPK 162
ATPase 145
prostate-specific antigen 140
superoxide dismutase 139
APC 132
MMP 128
collagenase 127
catalase 123
GSK 121
thrombin 120
reverse transcriptase 119
lactate dehydrogenase 116
granzyme B 112
arginase 106
calcineurin 100
alanine aminotransferase 95
ornithine decarboxylase 94
plasmin 91
firefly luciferase 82
RNase 81
glutathione S-transferase 81
matrix metalloproteinase 2 81
topoisomerase 79
topoisomerase 76
aldehyde dehydrogenase 76
beta-galactosidase 76
aldehyde dehydrogenase 75
trypsin 75
peroxidase 75
cytosine deaminase 74
RNase 74
aldehyde dehydrogenase 73
aldehyde dehydrogenase 73
aldehyde dehydrogenase 73
RNA polymerase 71
thymidylate synthase 69
aspartate aminotransferase 69
alkaline phosphatase 69
PDK1 68
matrix metalloproteinase 9 66
DNA methyltransferase 65
hyaluronidase 63
NO synthase 63
cathepsin B 62
hyaluronidase 62
ALDH 59
DCF 57
IKK 57
glutathione peroxidase 57
MDR 50
demethylase 50
TAT 49
MAP 49
ribonucleotide reductase 48
polo-like kinase 1 47
complex I 46
pyruvate kinase 46
ribonucleotide reductase 45
glutaminase 44
more...
Compound
DNA 4089
Dec 3759
oxygen 2127
Clin 2007
MDA 1414
MTT 1059
PEG 937
water 917
glucose 917
tyrosine 824
PEG 692
TNF 618
ATP 587
phosphate 532
calcium 496
ACS 472
ACS 468
arginine 451
methionine 434
MEK 426
lysine 406
iron 389
serine 375
sulfate 350
nitric oxide 349
cysteine 348
sodium 327
acetate 326
DBA 304
TNM 297
bromide 291
Adriamycin 286
iodine 285
DDP 283
ADR 272
5-FU 263
zinc 243
hyaluronic acid 236
hydrogen 232
nitrogen 222
threonine 218
glutamine 218
GSH 216
retinoic acid 216
GSH 216
copper 205
anthracene 191
leucine 189
dUTP 184
galactose 182
ethanol 171
urea 166
DBA 165
DBA 165
Asp 159
cAMP 154
alanine 152
Paclitaxel 151
Phe 142
Gly 140
PGE2 140
glutamate 138
Curcumin 137
CTX 133
AMP 131
Estrogen 125
pyrimidine 122
tryptophan 121
pyrimidine 121
Estrogen 120
boron 115
His 115
selenium 114
PGE 114
SCC 114
MIA 114
BCG 112
ADP 111
NH2 108
Tamoxifen 107
more...