Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0598934 (tumor growth)
 58,965 document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Mol 4544
Sep 3511
vascular endothelial growth factor 2311
p53 2079
cytokine 1829
AKT 1685
CD8 1568
caspase-3 1455
VEGF 1365
mTOR 1317
Bcl-2 1162
PI3K 1140
epidermal growth factor receptor 969
CD4 935
tyrosine kinase 927
cage 923
ERK 912
catenin 857
IFN 843
p21 815
tumor necrosis factor 791
STAT3 783
MAPK 775
cyclin D1 754
interferon 665
EGFR 664
IL-6 664
estrogen receptor 644
collagen 637
osteosarcoma 627
E-cadherin 621
TNF 618
ATP 587
CD44 573
ERK1 572
matrix metalloproteinase 569
chemokine 561
PEG 557
colon carcinoma 545
HER2 534
VEGFR2 527
PARP 525
MMP-9 501
CD31 500
Ki-67 497
lymphoid 485
ACS 468
IL-2 467
IFN-gamma 458
p38 445
insulin 434
PC-3 431
MEK 430
receptor tyrosine kinase 423
c-Myc 415
MMP-2 407
survivin 402
IL-10 397
PD-1 394
PTEN 391
ROS 390
PD-L1 385
endoplasmic reticulum 385
proteasome 384
proliferating cell nuclear antigen 384
MRI 376
fibronectin 376
UTR 367
Vascular endothelial growth factor 361
histone 361
p27 358
androgen receptor 346
IL-8 341
caspase-9 340
JNK 336
epidermal growth factor 335
BRAF 330
PC3 323
endostatin 316
COX-2 307
extracellular signal-regulated kinase 306
F10 306
TNM 298
vimentin 295
cyclooxygenase-2 292
interleukin-2 290
NOD 282
glycoprotein 282
KRAS 282
vascular endothelial growth factor receptor 280
fused 280
CXCR4 279
annexin V 276
interleukin-6 272
caspase-8 271
EGF 270
cytochrome c 269
p65 266
histone deacetylase 265
somatostatin 260
ubiquitin 258
CD133 254
CD11b 244
MHC 242
IL-4 242
hepatocyte growth factor 240
vascular endothelial growth factor A 240
insulin-like growth factor 237
thymus 237
signal transducer and activator of transcription 3 236
N-cadherin 235
EMT 231
PBS 224
urokinase-type plasminogen activator 222
MMP9 216
CDK4 215
CXCL12 215
thymidine kinase 214
phosphatidylinositol 3-kinase 213
CD34 212
CCK 211
cyclin 209
neu 207
protein kinase B 207
GSH 207
Mcl-1 205
TGF-beta 203
phosphatase 202
c-myc 199
polypeptide 199
prolactin 198
phosphoinositide 3-kinase 196
Fas 195
MYC 195
Cytokine 194
NMR 193
CD25 192
VEGFR-1 192
platelet-derived growth factor 191
MET 190
rhabdomyosarcoma 189
c-Met 187
aromatase 187
lipopolysaccharide 187
TNF-alpha 184
GM-CSF 182
MHC class I 182
Walker 181
ras 181
gut 180
interferon-gamma 179
inducible nitric oxide synthase 175
P-glycoprotein 174
proto-oncogene 174
progesterone receptor 173
c-Jun 173
cyclooxygenase 172
albumin 169
DBA 166
A431 164
more...
Disease
tumor growth 58965
tumor 41526
cancer 32490
breast cancer 5661
tumor progression 4431
carcinoma 3881
tumorigenesis 3757
melanoma 3660
metastases 3340
hepatocellular carcinoma 2745
prostate cancer 2340
lung cancer 2264
adenocarcinoma 2248
carcinogenesis 1918
colorectal cancer 1826
glioma 1756
tumor angiogenesis 1694
colon cancer 1517
pancreatic cancer 1366
squamous cell carcinoma 1293
glioblastoma 1266
MCF 1223
ovarian cancer 1174
lung carcinoma 1106
non-small cell lung cancer 1093
gastric cancer 1067
primary tumor 1043
sarcoma 891
leukemia 870
SCID 849
lymphoma 784
solid tumor 724
renal cell carcinoma 710
osteosarcoma 699
mammary tumor 677
liver cancer 667
fibrosarcoma 647
brain tumor 612
neuroblastoma 605
multiple myeloma 601
tumor vasculature 570
aggressiveness 550
cervical cancer 524
bladder cancer 519
liver cancer 516
lung metastases 504
glioblastoma multiforme 457
epithelial ovarian cancer 447
Hepatocellular carcinoma 384
tumor initiation 353
B-cell lymphoma 322
NOD 282
Melanoma 274
Glioblastoma 267
acute myeloid leukemia 261
retinoblastoma 255
herpes simplex 253
metastatic breast cancer 245
metastatic melanoma 241
obesity 239
EMT 231
endometrial cancer 229
diabetes 227
liver metastases 224
Blocking 222
GSH 207
esophageal cancer 206
DDP 197
skin cancer 182
esophageal cancer 181
thyroid cancer 181
bone metastases 179
adenoma 177
renal cancer 176
suicide 176
head and neck cancer 172
medulloblastoma 168
DBA 165
AS1 164
rhabdomyosarcoma 159
Osteosarcoma 158
Osteosarcoma 158
oral cancer 158
anemia 154
small cell lung cancer 153
residual disease 152
aggression 152
ischemia 151
Hodgkin's disease 146
Hippel 142
sarcoma 180 130
mesothelioma 129
astrocytoma 127
Ewing's sarcoma 126
infectious diseases 125
Neuroblastoma 124
Neuroblastoma 124
APC 122
Leukemia 121
atherosclerosis 121
hepatitis B 121
HCC 119
depression 119
hematologic malignancies 116
neoplastic transformation 115
virus infection 115
hypertension 115
meningioma 114
cirrhosis 113
HIV 113
cytomegalovirus 113
Epstein 111
ATM 109
mimicry 109
brain cancer 107
uterus 104
colitis 103
dysplasia 101
lymphatic vessels 101
cold 101
plaque 99
rheumatoid arthritis 97
PCL 97
schwannoma 96
chronic myeloid leukemia 96
Colon 94
Colon 94
Colon 94
Kaposi's sarcoma 94
pituitary tumor 93
Spleen 93
hypercalcemia 92
non-Hodgkin's lymphoma 91
vaccinia 91
HGF 88
bone disease 87
carcinosarcoma 86
malnutrition 85
EL4 82
carcinomatosis 79
PSA 79
brain metastases 79
AGS 78
epithelial tumor 78
acute lymphoblastic leukemia 75
arthritis 75
plasmacytoma 75
intracranial tumors 75
papillary thyroid cancer 75
chondrosarcoma 74
Sarcoma 74
Sarcoma 74
WT1 74
mole 73
transitional cell carcinoma 73
carcinoid 73
chronic lymphocytic leukemia 73
Infection 72
Tumour necrosis 72
Burkitt's lymphoma 71
more...
Symptom
cachexia 257
pain 248
starvation 174
anorexia 102
exhaustion 95
diarrhea 79
collapse 76
fatigue 67
splenomegaly 63
anesthesia 61
seizures 54
acidity 54
headache 52
nausea 44
bone pain 43
cancer pain 40
vomiting 33
abdominal pain 29
weakness 29
HSA 28
dyspnea 27
analgesia 24
thinning 16
discomfort 16
discomfort 16
overweight 16
erythema 15
tinnitus 14
ataxia 14
nausea and vomiting 13
hypothermia 12
Scratch 12
hyperoxia 12
flushing 12
numbness 10
constipation 10
cough 10
paresis 10
respiratory distress 9
hemoptysis 9
hepatomegaly 9
asthenia 9
ENT 8
skin damage 8
myalgia 7
back pain 7
chills 7
facial pain 6
menopausal symptoms 6
wheezing 6
No adverse effect 6
Ill 6
emaciation 5
paresthesia 5
hoarseness 5
ophthalmoplegia 5
vertigo 5
dysuria 5
lethargy 4
flank pain 4
angina 4
hepatosplenomegaly 4
hypercapnia 4
dizziness 4
acute stress 4
arthralgia 4
hot flushes 4
masculinization 3
functional recovery 3
insomnia 3
chest pain 3
tense 3
neurological disability 3
syncope 3
Cushingoid 3
muscle cramps 3
Cushingoid 3
abdominal discomfort 3
decreased appetite 3
disturbed balance 2
knee pain 2
stigma 2
hemiplegia 2
acute pain 2
partial seizure 2
hypoproteinemia 2
memory loss 2
POA 2
paraparesis 2
Skin depigmentation 2
agitation 2
Welt 2
spasm 2
physical appearance 2
night sweats 2
shortness of breath 2
Psychiatric symptoms 2
sleepiness 2
neuralgia 2
dysesthesia 2
breakthrough pain 2
epigastric pain 2
low back pain 2
dry skin 2
tremor 2
productive cough 1
fever of unknown origin 1
Mills 1
tingling 1
dry eye 1
Hudson 1
Crawling 1
Neuropathic pain 1
halitosis 1
Severe pain 1
orofacial pain 1
blemishes 1
twitching 1
hot flashes 1
shoulder pain 1
hunger 1
distraction 1
lightheadedness 1
incoordination 1
hypocapnia 1
autodigestion 1
oliguria 1
peri-menopausal 1
neck pain 1
impaired motor coordination 1
acute abdomen 1
hypalgesia 1
thigh pain 1
abdominal cramps 1
nasal congestion 1
pleuritic chest pain 1
limb pain 1
stomach pain 1
tenesmus 1
Depressive symptoms 1
anal pain 1
clubbing 1
voice change 1
Postoperative pain 1
rhinorrhea 1
Stiffness 1
intestinal bleeding 1
excessive sweating 1
dysarthria 1
anosmia 1
despair 1
Anoxia 1
pallor 1
otalgia 1
Overlying 1
regurgitation 1
Perianal pain 1
torticollis 1
bitter taste 1
enuresis 1
more...
Drug
IL-2 473
IFN-gamma 445
ROS 390
lysine 307
CSF 271
Dermatol 217
Taxol 160
Meth 158
Bevacizumab 152
CTX 133
Adriamycin 132
Sorafenib 117
Herceptin 107
Docetaxel 94
MAP 94
ADR 90
vitamin E 81
CPT-11 73
uPA 70
ascorbate 69
Monit 63
ADM 62
Gefitinib 62
Cetuximab 62
CTX 60
Bortezomib 60
CTX 58
NVP 58
Imatinib 54
GEO 53
ICI 48
TAT 48
Cardiovasc 47
G-CSF 46
IFN-beta 44
Indomethacin 43
CAM 41
Erlotinib 41
NADH 38
Taxotere 37
EE2 37
Irinotecan 34
ETS 32
Everolimus 32
Gel 29
Cremophor EL 28
Zoledronic acid 27
Photofrin 27
Vorinostat 26
ABC 25
Estrogens 25
Arsenic trioxide 25
Bifidobacterium 25
DM1 25
ALA 25
Heme 24
Mutagen 24
Dasatinib 24
CCL 24
Zoledronic acid 23
Gleevec 23
Oxaliplatin 23
RFP 23
G418 23
Retinoic acid 22
Asn 22
caffeine 22
p75 21
Norplant 20
Emodin 20
TTC 20
Emodin 20
Angiotensin II 20
TAK 18
ENT 18
Fulvestrant 18
VCR 17
AMC 17
Simvastatin 17
Lipiodol 16
Growth hormone 16
IL-11 16
Rituximab 16
Gelatin 16
EPA 16
BLM 16
VCR 15
Nitric Oxide 15
Histamine 15
R1881 15
Vitamin A 15
Growth hormone 15
DHT 15
Vitamin E 15
DHT 15
Panitumumab 14
Nephron 14
Vandetanib 14
MRC 14
Tarceva 14
PTC 13
Etoposide 13
Glutathione 13
Leaf 13
Alanine 12
Vinorelbine 12
Kenyan 12
Fluorescein 12
Lovastatin 12
Albumin 12
Doxycycline 12
NBT 12
Fraction 12
ETA 11
Paraffin 11
Verteporfin 11
KGF 11
ROC 11
lactose 11
Glycyrrhiza 11
DNase I 11
Activin 11
Cilengitide 11
nitroglycerin 11
2-Methoxyestradiol 11
Imiquimod 10
Parkin 10
Parkin 10
ZnO 10
Portal 10
L-tyrosine 10
Artesunate 10
PTH 10
PMEA 10
Pemetrexed 10
Flavopiridol 10
THF 9
Batimastat 9
pyridoxal phosphate 9
Spectrum 9
Axitinib 9
Batimastat 9
Gelfoam 9
NOV 9
Cetrorelix 9
Phosphatidylserine 9
CDP 9
PDL 9
ACT 9
Spectrum 9
Sunitinib malate 9
CoCl2 8
Fragment 8
BCG vaccine 8
CoCl2 8
Ginseng 8
Ranitidine 8
citric acid 8
-deoxyadenosine 8
Ganciclovir 8
more...
Enzyme
ERK 3226
mitogen-activated protein kinase 2193
luciferase 1262
caspase-3 1128
focal adhesion kinase 962
protein kinase 765
PARP 577
MEK 563
ACS 471
proteasome 390
caspase-9 283
AMP-activated protein kinase 264
urokinase-type plasminogen activator 255
protein kinase C 223
thymidine kinase 214
phosphatidylinositol 3-kinase 213
caspase-8 201
phosphoinositide 3-kinase 196
cdc2 196
AMPK 178
P-glycoprotein 174
AMPK 162
ATPase 145
prostate-specific antigen 140
superoxide dismutase 139
APC 132
MMP 128
collagenase 127
catalase 123
GSK 121
thrombin 120
reverse transcriptase 119
lactate dehydrogenase 116
granzyme B 112
arginase 106
calcineurin 100
alanine aminotransferase 95
ornithine decarboxylase 94
plasmin 91
firefly luciferase 82
matrix metalloproteinase 2 81
glutathione S-transferase 81
RNase 81
topoisomerase 79
topoisomerase 76
beta-galactosidase 76
aldehyde dehydrogenase 76
trypsin 75
aldehyde dehydrogenase 75
peroxidase 75
cytosine deaminase 74
RNase 74
aldehyde dehydrogenase 73
aldehyde dehydrogenase 73
aldehyde dehydrogenase 73
RNA polymerase 71
aspartate aminotransferase 69
thymidylate synthase 69
alkaline phosphatase 69
PDK1 68
matrix metalloproteinase 9 66
DNA methyltransferase 65
NO synthase 63
hyaluronidase 63
cathepsin B 62
hyaluronidase 62
ALDH 59
DCF 57
glutathione peroxidase 57
IKK 57
demethylase 50
MDR 50
TAT 49
MAP 49
ribonucleotide reductase 48
polo-like kinase 1 47
complex I 46
pyruvate kinase 46
ribonucleotide reductase 45
protein phosphatase 2A 44
glutaminase 44
MIP 43
phosphodiesterase 43
tissue plasminogen activator 41
ricin 41
MMP-3 41
CD13 41
pyruvate dehydrogenase 40
caspase-1 40
lipoxygenase 40
CPT 39
phospholipase C 38
NADPH oxidase 37
prolyl hydroxylase 37
prostate-specific membrane antigen 37
cathepsin D 37
NADPH oxidase 36
DNA polymerase 35
renin 35
hexokinase 35
thymidine phosphorylase 34
NOS 34
indoleamine 2,3-dioxygenase 34
TSP-1 33
CPT 33
tyrosinase 33
CPT 33
SPC 33
NQO1 32
farnesyltransferase 32
thioredoxin reductase 32
adenylate cyclase 32
farnesyltransferase 32
histone demethylase 31
pyruvate dehydrogenase 31
carbonic anhydrase 31
pyruvate dehydrogenase 31
caspase-7 30
kinesin 30
caspase-7 30
MTD 30
succinate dehydrogenase 28
furin 28
CD10 28
lysozyme 27
neuraminidase 27
dihydropyrimidine dehydrogenase 27
methioninase 26
acid phosphatase 26
MAT 25
HK2 25
kallikrein 25
MAT 25
ribonuclease 24
glucose oxidase 24
dihydropyrimidine dehydrogenase 24
TdT 24
ribonuclease 24
phospholipase A2 23
transglutaminase 23
AST 22
ACE 22
glucose-6-phosphate dehydrogenase 21
legumain 21
sulfatase 21
histone acetyltransferase 20
DNase 19
tryptase 19
neutrophil elastase 19
endonuclease 19
gamma-glutamyl transpeptidase 19
guanylate cyclase 19
cathepsin L 18
elastase 18
tyrosine hydroxylase 18
MEKK1 18
thromboplastin 18
transcriptase 18
lysyl oxidase 18
lipase 17
more...
Compound
DNA 4089
Dec 3759
oxygen 2127
Clin 2007
MDA 1414
MTT 1059
PEG 937
water 917
glucose 917
tyrosine 824
PEG 692
TNF 618
ATP 587
phosphate 532
calcium 496
ACS 472
ACS 468
arginine 451
methionine 434
MEK 426
lysine 406
iron 389
serine 375
sulfate 350
nitric oxide 349
cysteine 348
sodium 327
acetate 326
DBA 304
TNM 297
bromide 291
Adriamycin 286
iodine 285
DDP 283
ADR 272
5-FU 263
zinc 243
hyaluronic acid 236
hydrogen 232
nitrogen 222
glutamine 218
threonine 218
GSH 216
GSH 216
retinoic acid 216
copper 205
anthracene 191
leucine 189
dUTP 184
galactose 182
ethanol 171
urea 166
DBA 165
DBA 165
Asp 159
cAMP 154
alanine 152
Paclitaxel 151
Phe 142
PGE2 140
Gly 140
glutamate 138
Curcumin 137
CTX 133
AMP 131
Estrogen 125
pyrimidine 122
tryptophan 121
pyrimidine 121
Estrogen 120
boron 115
His 115
MIA 114
PGE 114
selenium 114
SCC 114
BCG 112
ADP 111
NH2 108
Vimentin 107
Tamoxifen 107
PEI 106
PEI 106
Metformin 105
Tamoxifen 105
Metformin 105
N-acetylcysteine 103
Insulin 101
tryptophan 100
ADP 98
ADP 97
TEM 97
tryptophan 97
tryptophan 97
proline 96
salt 96
Gemcitabine 95
Gemcitabine 95
NAD 94
MCA 93
ASA 91
MCA 90
GM1 86
vitamin D 86
BCNU 82
ADP-ribose 81
GTP 77
CO2 76
THP 75
THP 74
Pac 74
Docetaxel 72
CPT-11 72
NADPH 70
NADPH 70
MTS 67
ammonium 66
MAP 65
H2O2 65
pyridine 64
glutamic acid 64
creatinine 63
NAD 63
SDS 62
Celecoxib 61
MBT 61
PLA 61
PMA 61
ABL 60
Androgen 60
carbonate 59
Thyroid 59
COX 58
Histone 58
PDT 58
Rapamycin 57
potassium 56
PGA 56
NKT 56
MMC 55
Optimal 55
pentose 54
pentose 54
manganese 54
DMSO 54
pentose 54
CAM 54
pentose 54
Melatonin 53
nicotinamide 53
Neo 52
ethyl acetate 52
Ile 52
cobalt 52
ICI 51
MDR 51
Progesterone 50
Hoechst 33342 50
aspartic acid 49
BCR 49
more...