Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0598853 (forgetting)
3,232 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Successfully retrieving information protects it against later forgetting. Failed retrieval attempts are also beneficial if followed by study of corrective feedback. To explain both of these findings, researchers have proposed the mediation hypothesis. In the case of learning from corrective feedback, initial errors may serve as mediators, becoming associated with the corrective information and assisting with recall of that information during later retrieval attempts. A simple prediction follows: reminding learners of their initial errors should improve their recall of the corrections. We tested this prediction with a set of 3 experiments. In Experiment 1, participants learned cue-target word pairs (e.g., cactus-point) by reading or by incorrectly guessing target words before viewing corrective feedback. Immediately afterward, participants were equally good at recalling targets from the cue alone, the cue plus their own guess, or the cue plus a guess made by another participant. Experiment 2 produced similar results when the retention test was delayed by 24 hr. In Experiment 3, participants instead learned word triplets having a mediational relationship through preexisting associations (e.g., film-star-galaxy). Here, reminding participants of a genuine mediator greatly improved target recall, supporting the validity of our cueing procedure. (PsycINFO Database Record (c) 2020 APA, all rights reserved).
...
PMID:Errors may not cue recall of corrective feedback: Evidence against the mediation hypothesis of the testing effect. 3194 9

Objective: Studies have shown that patients with anterograde amnesia forget less episodic information after a delay if encoding is immediately followed by an unfilled period of wakeful rest. This benefit has been attributed to the reduced interference with the consolidation process. However, this account cannot directly explain improved retention in healthy adults resulting from pre-encoding rest. While benefits resulting from pre- and post-encoding rest can be alternatively explained via improved distinctiveness at retrieval, it has yet to be established whether both benefits are observable in amnesics. The aim of the current study was to assess whether amnesic patients showed improved retention of prose material after 10 min following both pre- and post-encoding unfilled intervals of wakeful rest. Method: Twelve patients with anterograde amnesia were recruited. Participants completed four conditions. A short prose passage was aurally presented in each condition. Prose presentation was preceded and followed by a 9-min delay interval. Delay intervals were either filled (spot-the-difference task) or unfilled (wakeful rest). Prose retention was assessed immediately after presentation and after 10 min. Results: Prose retention was consistently better when wakeful rest followed prose encoding in comparison to a condition where an effortful task was encountered both before and after encoding. Conclusions: Post-encoding wakeful rest alone substantially improves retention in amnesic patients. While pre-encoding wakeful rest elicits inconsistent benefits in amnesics, reduced retention following both pre- and post-encoding task engagement suggests that pre-encoding activity may still be relevant. Overall, our findings support consolidation interference explanations of forgetting in anterograde amnesia. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
...
PMID:Wakeful rest benefits before and after encoding in anterograde amnesia. 3223 72

Selective amnesia for previously established memories can be induced by administering drugs that impair protein synthesis shortly after memory reactivation. Competing theoretical accounts attribute this selective post-retrieval amnesia to drug-induced engram degradation (reconsolidation blockade) or to incorporation of sensory features of the reactivation experience into the memory representation, hampering later retrieval in a drug-free state (memory integration). Here we present evidence that critically challenges both accounts. In contextual fear conditioning in rats, we find that amnesia induced by administration of midazolam (MDZ) after reexposure to the training context A generalizes readily to a similar context B. Amnesia is also observed when animals are exposed to the similar context B prior to MDZ administration and later tested for fear to context B but recovers when instead testing for fear to the original training context A or an equally similar but novel context C. Next to their theoretical implications for the nature of forgetting, our findings raise important questions about the viability of reconsolidation-based interventions for the treatment of emotional disorders. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
...
PMID:Generalization and recovery of post-retrieval amnesia. 3229 79

People see themselves as better than average in many domains, from leadership skills to driving ability. However, many people-especially older adults-struggle to remember others' names, and many of us are aware of this struggle. Our beliefs about our memory for names may be different from other information; perhaps forgetting names is particularly salient. We asked younger and older adults to rate themselves compared with others their age on several socially desirable traits (e.g., honesty); their overall memory ability; and their specific ability to remember scientific terms, locations, and people's names. Participants demonstrated a better-than-average (BTA) effect in their ratings of most items except their ability to remember names, which both groups rated as approximately the same as others their age. Older adults' ratings of this ability were related to a measure of the social consequences of forgetting another's name, but younger adults' ratings were not. The BTA effect is present in many judgments for both younger and older adults, but people may be more attuned to memory failures when those failures involve social consequences. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
...
PMID:Remembering proper names as a potential exception to the better-than-average effect in younger and older adults. 3235 5

Cognitively suppressing the retrieval of an unwanted memory causes its forgetting and, in the meantime, disrupts hippocampal functions. The present study investigated whether retrieval suppression induces virtual amnesia, which disturbs any existing memories that are reactivated in the temporal vicinity but are otherwise unrelated to the targets of suppression. Participants performed retrieval suppression on a set of memories while cues of an unrelated set of memories were briefly presented near in time to the suppression trials. Results showed that retrieval suppression impaired the retrieval of both the directly suppressed content and the reactivated unrelated memory. This amnesic shadow functioned in both the forward and backward temporal directions, and its forgetting effect was revealed by independent cues that were not presented in the shadow. Remarkably, a negative memory could be impaired simply by presenting it between the suppression episodes of an unrelated neutral memory. These findings provide support for systemic influence of retrieval suppression on hippocampal functions and offer a way to disrupt existing episodic memory strategically. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
...
PMID:Forgetting unrelated episodic memories through suppression-induced amnesia. 3279 Apr 59

We present the context-unified encoding (CUE) model, a large-scale spiking neural network model of human memory. It combines and integrates activity-based short-term memory (STM) with weight-based long-term memory. The implementation with spiking neurons ensures biological plausibility and allows for predictions on the neural level. At the same time, the model produces behavioral outputs that have been matched to human data from serial and free recall experiments. In particular, well-known results such as primacy, recency, transposition error gradients, and forward recall bias have been reproduced with good quantitative matches. Additionally, the model accounts for the Hebb repetition effect. The CUE model combines and extends the ordinal serial encoding model, a spiking neuron model of STM, and the temporal context model, a mathematical memory model matching free recall data. To implement the modification of the required association matrices, a novel learning rule, the association matrix learning rule, is derived that allows for one-shot learning without catastrophic forgetting. Its biological plausibility is discussed and it is shown that it accounts for changes in neural firing observed in human recordings from an association learning experiment. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
...
PMID:CUE: A unified spiking neuron model of short-term and long-term memory. 3281 8

We report 3 empirical studies that represent the first systematic attempt to explore the relationship between emotional and decisional forgiveness and intentional forgetting. On this basis, we propose a model that provides a credible explanation for the relationship between forgiveness and forgetting. Specifically, we propose that engaging in emotional forgiveness promotes the psychological distancing of an offense, such that victims construe the offense at a higher and more abstract level. This high-level construal, in turn, promotes larger intentional forgetting effects, which, in turn, promote increased emotional forgiveness. Our studies found that participants in an emotional forgiveness manipulation reported increased psychological distance and recalled more high-level construals than did participants in either a decisional or no-forgiveness manipulation (Study 1). Using the list-method directed forgetting paradigm, we found that participants in an emotional forgiveness manipulation showed larger forgetting effects for both offense-relevant and -irrelevant information using both hypothetical (Study 2) and real-life (Study 3) moral transgressions compared with participants in either decisional or no-forgiveness manipulations. The potential implications of these findings for coping with unpleasant episodes in our lives are considered. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
...
PMID:Moving on or deciding to let go? A pathway exploring the relationship between emotional and decisional forgiveness and intentional forgetting. 3288 61

Few studies have compared interference-based forgetting between item versus associative memory. The memory-system dependent forgetting hypothesis (Hardt, Nader, & Nadel, 2013) predicts that effects of interference on associative memory should be minimal because its hippocampal representation allows pattern separation even of highly similar information. In contrast, there should be strong interference effects on extra-hippocampally represented item memory. We tested this prediction in behavioral data from 3 experiments using continuous recognition paradigms. Given older adults' greater deficits in associative than item memory, we also compared younger and older adults to test whether this associative deficit extends to greater interference susceptibility in older adults' associative memory. Experiment 1 examined item-item associative memory with participants studying unrelated word pairs continuously intermixed with item (single words) and associative (intact vs. recombined pairs) recognition tests across interference-filled lags. Experiments 2 and 3 examined item-context (i.e., source) associative memory with participants studying words in different spatial positions continuously intermixed with source-monitoring tests (presented on top vs. on bottom vs. new?) across interference-filled lags (Experiment 3 controlling for delay/decay-based effects). In all experiments, item memory declined from the first lag on. In contrast, associative memory initially remained stable, with strong evidence for null effects of interference even in older adults, but showed some declines at later lags. The data supports Hardt et al.'s proposal of differential interference-based forgetting in item versus associative memory. The results further show that the age-related associative memory deficit does not extend to greater interference-based forgetting in older adults' associative memory. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
...
PMID:Longer resistance of associative versus item memory to interference-based forgetting, even in older adults. 3300 1

Adapting to task changes in work settings frequently calls not only for shifting one's thoughts and behaviors to the new demands, but also for dealing with outdated knowledge and skills. This article focuses on the role of control strategies in task adaptation and reports two experimental studies using an air traffic control simulation task. In both studies (N = 66 and 105 with k = 1,320 and 1,680 observations, respectively), all participants first learned and performed an initial version of the task then received instruction about control strategies, performed an altered version of the task with new execution rules, and finally worked on a memory test. Participants were instructed to either deliberately forget the old rules, remember the old rules, or simply learn the new task (Study 2 only). Results from discontinuous growth curve modeling revealed that the directed forgetting in both studies and the control group in Study 2 showed higher performance in the simulation after the change relative to their performance before the change (transition adaptation). There were no relearning differences between the groups suggesting that these differences persisted throughout the task. However, the memory test at the end of the study revealed that the directed forgetting groups and the learning control group remembered less outdated task execution rules in the memory test after the simulation than the remembering group. The findings suggest that different types of cognitive strategies have costs and benefits. Conceptual and practical implications of these findings are discussed. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
...
PMID:Cognitive control strategies and adaptive performance in a complex work task. 3303 Sep 21

It is still debated whether suppressing the retrieval of unwanted memories causes forgetting and whether this constitutes a beneficial mechanism. To shed light on these 2 questions, we scrutinize the evidence for such suppression-induced forgetting (SIF) and examine whether it is deficient in psychological disorders characterized by intrusive thoughts. Specifically, we performed a focused meta-analysis of studies that have used the think/no-think procedure to test SIF in individuals either affected by psychological disorders or exhibiting high scores on related traits. Overall, across 96 effects from 25 studies, we found that avoiding retrieval leads to significant forgetting in healthy individuals, with a small to moderate effect size (0.28, 95% CI [0.14, 0.43]). Importantly, this effect was indeed larger than for more anxious (-0.21, 95% CI [-0.41, -0.02]) or depressed individuals (0.05, 95% CI [-0.19, 0.29])-though estimates for the healthy may be inflated by publication bias. In contrast, individuals with a stronger repressive coping style showed greater SIF (0.42, 95% CI [0.32, 0.52]). Furthermore, moderator analyses revealed that SIF varied with the exact suppression mechanism that participants were instructed to engage. For healthy individuals, the effect sizes were considerably larger when instructions induced specific mechanisms of direct retrieval suppression or thought substitution than when they were unspecific. These results suggest that intact suppression-induced forgetting is a hallmark of psychological well-being, and that inducing more specific suppression mechanisms fosters voluntary forgetting. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
...
PMID:Memory suppression and its deficiency in psychological disorders: A focused meta-analysis. 3309 Aug 24


<< Previous 1 2 3 4