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Query: UMLS:C0598853 (forgetting)
 3,232 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Without forgetting that resection of a malignant tumour must always take priority over the problems of reconstruction, based on a series of 105 cases of medial canthus lesions, the authors believe that: for tumours with a reserved prognosis, particularly sclerodermiform basal cell carcinomas of the orbit, full thickness skin graft is the most appropriate technique; for cases with a good prognosis, the cosmetic result takes priority. An intersuperciliary island flap is currently the method of choice; for advanced cancers of the medial canthus, the combination of frontal flaps and nasolabial flaps is the procedure which gives the best aesthetic and functional results. This series includes three cases of radical orbital exenteration, including two because of sclerodermiform basal cell carcinomas, and the authors stress the very serious prognosis of these tumours in the orbit, especially in the presence of a recurrence in an irradiated territory.
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PMID:[Reconstruction of the medial canthus in oncology. Apropos of 105 cases over 9 years]. 172 83

Renal lithiasis is a frequent disease which recurs in more than 60% of cases. Effective prevention of recurrence can be obtained once the cause has been identified. The laboratory investigation, based on clinical history, analysis of the stone and blood and urine assays, achieves this objective. As the stone is the main indicator of lithogenic disorders, the investigation must start by morphoconstitutional analysis of the stone by reliable physical methods. The results of this analysis guide the clinician towards the biochemical factors responsible for the lithogenic process and, in some cases, directly to certain infectious diseases, such as infections due to urease-positive bacteria, or metabolic diseases, such as primary hyperoxaluria, tubular acidosis or enzymatic deficits of purine metabolism, without forgetting drug causes, responsible for the formation of approximately one per cent of stones. Subsequent investigations guided by analysis of the stone are therefore much more selective and rational. When the stone is not available, the investigation, graduated according to the metabolic activity of the lithiasis, can be guided by its radiological appearance. Dynamic investigations are rarely necessary and must be reserved a second-line procedures for the most severe forms of calcium-dependent stones. In the absence of radiological data and when the stone has not been collected, a basic routine blood and urine investigation must be performed looking for laboratory factors potentially involved in the stone-forming process.
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PMID:[Metabolic assessment of urinary lithiasis in routine practice. Common task of nephrologists and urologists of the Lithiasis Committee of the French Association of Urology]. 923 85

About 600 injections per year are administered in a Luxembourg family planning center using 3 types of long acting progestatives: Depo Provera 150 and 450 and Norigest. The method is no longer reserved for women with completed families and the mentally handicapped since its reversibility has been proven. Patients seeking this type of contraception must meet the same criteria as for oral contraceptives except that women with contraindications for estrogens may tolerate progestatives. Long acting progestatives offer the safety of minipills along with high effectiveness since the risk of forgetting a pill is removed. Some women with cardiac disease, diabetes, and circulatory problems are able to use injectables, but caution should be exercised with hypertensives and the obese because of possible weight gain. Women with coagulation problems or suspected fibromas should be excluded. Administered postpartum, pure progestatives do not affect lactation. Menstrual cycles are completely disturbed, with irregular and unpredictable bleeding until amenorrhea appears after 3-6 months. Women who are psychologically unable to accept amenorrhea should not use this method, as they are more likely to experience undesirable side effects. Return of fertility upon termination of use poses no problem and usually occurs after 6-10 months, even after a single injection. Treatment with a sequential contraceptive beginning on the day when the next injection would have been given may help to reestablish menstruation. The physician should determine through a preliminary interview the couple's psychological readiness for this type of contraception. A careful medical history and gynecological examination should be done to rule out contraindications, and treatment should begin in the 1st 3 days of the cycle. Irregular and prolonged bleeding after 6 months of use can be treated with oral administration of estrogen, or by proceeding to the next injection ahead of schedule. Administration of a mild diuretic is rarely necessary for water retention. Pregnancy during use of the method is very rare but usually occurs after the 2nd or 3rd treatment and may be detected only in the 3rd or 4th month. Uterine size should be assessed at each treatment for the 1st year. Short term local treatment with estrogen rapidly restores vaginal lubrication when necessary. No serious incidents have occurred with use of long acting progestatives at this clinic.
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PMID:[Indications and medical survey of long acting progestatives used for contraception (author's transl)]. 1233 49

In 181 urban African Americans with Type 2 diabetes, medication adherence was assessed using a measure designed specifically for an urban, impoverished sociodemographic population. Hemoglobin A-sub(1c), blood pressure and cholesterol levels, medication-related beliefs, and depression were assessed. Seventy-four percent of the sample reported adherence to diabetes medication. Adherence, adjusted for age, was associated with lower hemoglobin A-sub(1c). The specific behaviors associated with poorer diabetes control were forgetting to take medications and running out of medications. Knowledge of blood glucose goals differed for adherers and nonadherers. Blood pressure and cholesterol medication adherence rates were not associated with actual levels of blood pressure or lipids, respectively. These data suggest that specific medication-taking behaviors are important to diabetes control and constitute logical targets for interventions. ((c) 2005 APA, all rights reserved).
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PMID:Medication adherence and diabetes control in urban African Americans with type 2 diabetes. 1604 70

Six experiments examined the proposal that an item of long-term knowledge can be simultaneously inhibited and activated. In 2 directed forgetting experiments items to-be-forgotten were found to be inhibited in list-cued recall but activated in lexical decision tasks. In 3 retrieval practice experiments, unpracticed items from practiced categories were found to be inhibited in category-cued recall but were primed in lexical decision. If, however, the primes and targets in lexical decision were taken directly from the study list, inhibition was observed. Finally, it was found that when items highly associated with a study list were processed in between study and test, no inhibition in recall was present. These, and a broad range of other findings, can be explained by the concept of "episodic inhibition," which proposes that episodic memories retain copies of semantic knowledge structures that preserve patterns of activation/inhibition originally generated in those structures during encoding. ((c) 2006 APA, all rights reserved).
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PMID:Episodic inhibition. 1647 39

In list-method directed forgetting, participants are cued to intentionally forget a previously studied list (List 1) before encoding a subsequently presented list (List 2). Compared with remember-cued participants, forget-cued participants typically show impaired recall of List 1 and improved recall of List 2, referred to as List 1 forgetting and List 2 enhancement. In 3 experiments, we examined how amount of postcue encoding influences directed forgetting. Two results emerged dissociating List 1 forgetting from List 2 enhancement. First, an increase in amount of postcue encoding led to an increase in List 1 forgetting but did not affect List 2 enhancement. Second, the forget cue influenced all List 1 items but affected only early List 2 items. A 2-mechanism account of directed forgetting is suggested, according to which List 1 forgetting reflects reduced accessibility of List 1 items, and List 2 enhancement arises from a reset of encoding processes. (PsycINFO Database Record (c) 2009 APA, all rights reserved).
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PMID:Amount of postcue encoding predicts amount of directed forgetting. 2005 44

Some general and specific, statutory, clinical and biological parameters have to be taken into account before beginning chemotherapy in colorectal cancer to ensure maximal safety. Statutorily the prescription is reserved to specialised or competent physicians in oncology in some accredited institutions. It is essential to conform to indications, contraindications and posology, and to have a good knowledge of safety measures, drug interactions and side effects. Patients, family members and general practitioners should be informed about side effects, without forgetting some thematics (sexuality, fertility, contraception, vaccines, driving). This information should be simple, adapted and "reassuring", but should focus on symptoms indicating a serious toxic side effect. The message can be optimized by nurse consultation, transmission of the individualized care plan and linkage notebook, such as oral chemotherapies (capecitabine, UFT). The computerized and standardized prescription is done after infusion line inspection, clinical examination (global health status, nutritional status and buccodental status) and review of relevant pathological, radiological and biological data. Management of side effects includes patient education, appropriate premedication and prescription of prophylactic supportive care. Some specific preventive measures can attenuate the cutaneous side effects of EGFR inhibitors and the oxaliplatine-induced sensory neurotoxicity. Life expectancy, comorbidities, level of dependence, and if possible the comprehensive geriatric assessment should be taken into account for elderly patients. Prescription should be individualized and adapted to liver biology (irinotecan), kidney function (capecitabine and raltitrexed) and cardiovascular status (bevacizumab, 5-FU, capecitabin). Some molecular biologic prerequisites are indicated: detection of tumor KRAS-BRAF mutation before anti-EGFR and tumor microsatelliteinstability status before 5-FU in stage II cancers. Clinical relevance of others pretherapeutic molecularparameters are still being evaluated: UGT1A1 genotyping before irinotecan and detection of dihydropyrimidine dehydrogenase deficiency before fluoropyrimidines.
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PMID:[Prerequisites to the administration and prevention of adverse effects of chemotherapy in colorectal cancer]. 2008 Apr 56

The sources of forgetting in working memory remain the matter of intense debate. According to the SOB model (serial order in a box; Farrell & Lewandowsky, 2002), forgetting in complex span tasks does not result from temporal decay but from interference produced by the encoding of distractors that are superimposed over memory items onto a composite memory. The main tenet of the model is that the encoding strength of a distractor is a function of its novelty, with novel distractors being encoded with a large encoding weight that interferes with other memories, whereas repeated distractors would result in negligible encoding weight and no further forgetting. In the present study, we tested the 2 main predictions issuing from this model. First, recall performance should be better in complex span tasks in which distractors are repeated than in tasks in which every distractor is novel. Second, increasing the number of novel distractors should lead to more interference and poorer recall. In 5 experiments in which we controlled for attentional demand and temporal factors, none of these predictions were verified, whereas a strong effect of the pace at which distracting tasks were performed testified that they involved forgetting. We conclude that, contrary to the SOB model, the novelty of distractors plays no role per se in forgetting. (PsycINFO Database Record (c) 2013 APA, all rights reserved).
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PMID:Forgetting from working memory: does novelty encoding matter? 2256 35

Among the fathers of transsphenoidal surgery, a relevant role should be reserved for Cesare Cavina (1888-1935). He had the merit to develop and popularize in Italy this approach for pituitary tumors, performing 47 transsphenoidal hypophysectomies out of his personal series of 66 patients between 1927 and 1935. He contributed to this surgery by introducing radiological control of the surgical trajectory to reduce the risk of complications and increase the safety of this approach. We think that both his short lifespan (he died when he was 47 years old) and the language of his papers (Italian and not English) are two important factors that have contributed to forgetting his role in the history of transsphenoidal surgery. We think that Prof. Cesare Cavina is definitively one of the fathers of transsphenoidal surgery and that it is important to preserve his memory.
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PMID:Cesare Cavina (1888-1935): a father of transsphenoidal surgery. 2589 81

Demonstrations of emotional Stroop in conditioned made-up words are flawed because of the lack of task ensuring similar word encoding across conditions. Here, participants were trained on associations between made-up words (e.g., 'drott') and pictures with an alarming or neutral content (e.g., 'a dead sheep' vs. 'a munching cow') in a situation that required attention to both ends of each association. To test whether word emotional attributes need to consolidate before they can hijack attention, one set of associations was learned seven days before the test, whereas the other set was learned either six hrs or immediately before the test. The novel words' ability to evoke their emotional attributes was assessed by using both Stroop and an auditory analogue called pause detection. Matching words and pictures was harder for alarming associations. However, similar learning rate and forgetting at seven days were observed for both types of associations. Pause detection revealed no emotion effect for same-day (i.e., unconsolidated) associations, but robust interference for seven-day-old (i.e., consolidated) alarming associations. Attention capture was found in the emotional Stroop as well, though only when trial n-1 referred to a same-day association. This task also showed stronger response repetition priming (independently of emotion) when trials n and n-1 both tapped into seven-day-old associations. Word emotional attributes hence take between six hrs and seven days to be operational. Moreover, age interactions between consecutive trials can be used to gauge implicitly the indirect (relational) episodic associations that develop in the meantime between the memories of individual items. (PsycINFO Database Record (c) 2018 APA, all rights reserved).
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PMID:Setting the alarm: Word emotional attributes require consolidation to be operational. 2936 46


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