Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0598853 (forgetting)
 3,232 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

70 women, aged 37-59, were treated with Menonorm and Gotistron (3 cycles with each preparation) in a double-blind survey to determine which medication was more effective in treating menopausal symptoms. Menonorm was preferred to Gotistron for the relief of hot flashes and nervous symptoms. Menonorm brought improvement in hot flashes in 88% of the cases, Gotistron in 73%; these medications brought improvement in nervous symptoms in about 55% of the patients. 27% of the women who took part discontinued the experiment due to side effects, which were mild in 21% of these patients. 80% of the patients experienced some type of side effect. This double-blind study was not considered the best method for indicating which drug was more effective, due to the subjective nature of the patients' symptoms: 40% of the patients had to be excluded from the statistical analysis because of side effects or forgetting to take the medication.
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PMID:[Continuous graduated sequential therapy with estrogen-gestagen in the climacteric. A double-blind study]. 77 2

The oral hormonal agent anastrozole improves clinical outcomes for women with breast cancer, but women have difficulty taking it for the five-year course. The unique medication-taking experiences related to self-management of anastrozole therapy for women with early stage breast cancer are not known. Our purpose was to describe the medication-taking experiences for postmenopausal women with early stage breast cancer who were prescribed a course of anastrozole therapy. Twelve women aged 58 to 67 years, midway through therapy, participated in audio-recorded interviews. Women's medication-taking experiences involved a belief in their importance and an imperative to take anastrozole. We found that women's side effect experiences, particularly menopausal symptoms, were significant, but only one woman stopped anastrozole due to side effects. Medication-taking included routinization interconnected with remembering/forgetting and a storage strategy. Some women noted a mutual medication-taking experience with their spouse, but most felt taking anastrozole was something they had to do alone. Our results provide insight into the way some women with early stage breast cancer manage their hormonal therapy at approximately the midpoint of treatment. Next steps should include examinations of patient-provider communication, potential medication-taking differences between pre- and postmenopausal women, and the effects of medication-taking on clinical outcomes.
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PMID:"Keeping the Boogie Man Away": Medication Self-Management among Women Receiving Anastrozole Therapy. 2332 55