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Query: UMLS:C0598853 (forgetting)
 3,232 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Anterior thalamic (ATN) dysfunction produces memory deficits in rats and humans. The current study shows that, with a substantial delay between post-surgery tests, controls show repeated relearning on a spatial working memory task whereas rats with neurotoxic ATN lesions showed repeated relearning deficits. Rats were pre-trained to criterion, but not over trained, on the spatial task. ATN lesions produced the expected spatial memory and relearning deficits about two weeks post-surgery and again either one or 15 weeks later. Control rats also showed forgetting post-surgery and after a 15 week break, relearning the task on each occasion. Controls with only a 1 week break before their final re-test showed negligible forgetting. Thus, a short break between re-tests replicated previous findings with ATN lesions, but a long break allows repeated comparison of rates of learning from a common starting point in sham and ATN-lesioned animals, providing a useful paradigm for future testing of pro-cognitive treatments.
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PMID:Effects of thalamic lesions on repeated relearning of a spatial working memory task. 2433 78

Anterior compartment defect is the most common pelvic organ prolapse. It is defined as the descent of the bladder into the anterior vaginal wall. The etiology is multifactorial and the main risk factors are vaginal delivery and conditions associated with increased abdominal strain. Aging is significantly associated with the prevalence and severity of pelvic organ prolapse. Treatment may be conservative or surgical according to symptoms, prolapse degree and not forgetting both patient and doctor preferences. The aim of this work is to identify the most efficient surgical treatment of cystocele and its recurrences. There are two different surgical approaches for the treatment of cystocele: traditional repair and mesh repair. Prosthetic treatment gives higher anatomical success rate but traditional anterior repair has less complication demonstrating a lower risk of reoperation. Surgical treatment in general improves both the quality of life (QoL) and the sexual function. We carried out a research on the impact of the anterior defect before and after native tissue surgery on QoL and sexual function. The efficacy and complications of the treatment were also assessed.
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PMID:Effectiveness, quality of life and sexual functions in women with anterior compartment prolapse treated by native tissue repair. 3029 2