Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0598766 (
leukemogenesis
)
4,065
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
285
MLL
265
lymphoid
263
Mol
237
AML
207
tyrosine kinase
178
AML1
164
p53
160
RUNX1
156
histone
139
ALL
139
cytokine
133
FLT3
129
BCR
123
erythroid
115
ABL
114
TEL
113
chimeric protein
112
p13
105
thymus
104
fused
103
CD34
94
PML
91
AF9
90
ETO
89
all-trans
73
BCR/ABL
72
HOXA9
63
proto-oncogene
60
IL-3
60
STAT5
59
NPM1
53
AKT
53
MYC
52
histone deacetylase
52
granulocyte
51
homeobox
50
p15
49
hematopoietic stem and progenitor cells
49
mTOR
49
more...
Disease
leukemogenesis
4065
leukemia
2079
acute myeloid leukemia
1356
cancer
1204
tumor
614
acute lymphoblastic leukemia
534
Leukemia
390
lymphoma
292
chronic myeloid leukemia
276
myelodysplastic syndrome
251
acute leukemia
235
acute promyelocytic leukemia
173
myeloid leukemia
172
tumorigenesis
158
T-cell acute lymphoblastic leukemia
132
myeloproliferative disorders
116
ABL
114
lymphoblastic leukemia
108
PML
91
chronic lymphocytic leukemia
85
childhood ALL
79
hematologic malignancies
76
adult T-cell leukemia/lymphoma
75
chronic lymphocytic leukemia
74
carcinogenesis
73
B-ALL
66
Down syndrome
62
erythroleukemia
55
minimal residual disease
49
anemia
46
WT1
46
trisomy
45
SCID
37
MDS
36
blast crisis
34
chronic myelomonocytic leukemia
34
pediatric AML
32
bovine leukemia
31
tumor progression
29
NOD
27
more...
Symptom
splenomegaly
31
hepatosplenomegaly
11
starvation
8
exhaustion
4
bone pain
2
hepatomegaly
2
headache
1
hypotonia
1
weakness
1
cachexia
1
erythema
1
ataxic gait
1
loss of balance
1
respiratory distress
1
overweight
1
dyspnea
1
fatigue
1
nasal congestion
1
Drug
TEL
66
lysine
62
CSF
42
MDS
36
ETS
25
Imatinib
24
IL-2
21
G-CSF
17
Gleevec
15
Retinoic acid
9
Arsenic trioxide
6
Mutagen
5
MAP
5
Etoposide
5
MOF
4
ROS
4
Norplant
4
Asn
4
IFN-gamma
4
G418
4
DNase I
4
p75
4
CTX
3
AraC
3
NADH
3
MRC
2
ARA-C
2
RFP
2
Anagrelide
2
CDP
2
TAT
2
niacin
2
NVP
2
Dasatinib
2
ADM
1
Monit
1
Dacogen
1
ID2
1
ascorbate
1
Mizoribine
1
more...
Enzyme
ERK
247
focal adhesion kinase
208
mitogen-activated protein kinase
93
reverse transcriptase
52
protein kinase
48
topoisomerase
34
luciferase
33
RNA polymerase
29
DNA methyltransferase
28
topoisomerase
28
MEK
27
proteasome
25
histone acetyltransferase
23
phosphatidylinositol 3-kinase
22
peroxidase
20
CD10
18
caspase-3
15
calcineurin
15
cdc2
15
CD13
13
transcriptase
13
demethylase
12
glutathione S-transferase
12
phosphoinositide 3-kinase
9
isocitrate dehydrogenase
9
isocitrate dehydrogenase
9
protein phosphatase 2A
8
protein kinase C
8
PARP
8
IKK
7
catalase
7
factor C
7
GSK
6
ATPase
6
alkaline phosphatase
6
lysozyme
6
Rex
6
MAP
5
gamma-glutamyl transpeptidase
5
neutrophil elastase
5
more...
Compound
DNA
672
Dec
263
tyrosine
128
retinoic acid
124
Clin
124
BCR
123
ABL
114
lysine
69
TEL
66
benzene
55
oxygen
38
serine
37
zinc
28
Benzene
27
threonine
26
acetate
26
tryptophan
22
DBA
20
arginine
18
calcium
18
SET
17
MEK
17
urea
17
hydroquinone
16
ATP
16
DBA
15
DBA
15
leucine
14
anthracene
13
cysteine
12
glucose
12
Pac
12
AMP
11
Histone
11
hydroxyglutarate
10
THP
10
formaldehyde
10
THP
10
Ara-C
9
sodium
9
more...