Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0598766 (leukemogenesis)
 4,065 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 285
MLL 265
lymphoid 263
Mol 237
AML 207
tyrosine kinase 178
AML1 164
p53 160
RUNX1 156
ALL 139
histone 139
cytokine 133
FLT3 129
BCR 123
erythroid 115
ABL 114
TEL 113
chimeric protein 112
p13 105
thymus 104
fused 103
CD34 94
PML 91
AF9 90
ETO 89
all-trans 73
BCR/ABL 72
HOXA9 63
proto-oncogene 60
IL-3 60
STAT5 59
NPM1 53
AKT 53
MYC 52
histone deacetylase 52
granulocyte 51
homeobox 50
p15 49
hematopoietic stem and progenitor cells 49
mTOR 49
CD4 47
c-kit 47
retinoic acid receptor alpha 46
PI3K 46
methyltransferase 46
histone H3 46
p21 46
TAL1 46
c-fms 45
ras 44
NUP98 43
PU.1 41
p300 41
EVI1 41
FAB 40
E2A 40
MAPK 40
c-Myc 40
NRAS 40
receptor tyrosine kinase 39
env 39
ERK 38
KIT 38
CML 38
AF4 38
c-myc 37
WT1 37
phosphatase 37
promyelocytic leukemia 37
chromosome 21 36
MDS 36
CEBPA 36
RAR 36
telomeric 35
JAK2 35
CBFB 35
BCR-ABL1 34
MEIS1 33
p16 33
granulocyte colony-stimulating factor 33
bcr 33
ENL 33
DOT1L 32
transcriptional repressor 32
GM-CSF 32
MYH11 32
zinc finger 31
CD8 31
interferon 31
Bcl-2 31
PTPN11 30
N-ras 30
CD19 29
p11 29
cryptic 29
NOTCH1 29
ubiquitin 29
PTEN 28
AF10 28
TET2 28
DNA methyltransferase 28
DNA-binding domain 28
Ikaros 28
CBP 28
TCR 28
p210 27
IDH1 27
GATA1 27
catenin 27
NOD 27
DNMT3A 27
tyrosine kinase 3 26
nucleophosmin 26
proteasome 25
p190 25
CD11b 25
CBF 25
RARA 25
CD38 25
retinoic acid receptor 24
STAT 24
CD5 24
MYB 24
LMO2 24
macrophage colony-stimulating factor 24
caspase-3 23
T cell receptor 23
PLZF 23
breakpoint cluster region 23
BCL2 23
PAX5 23
histone acetyltransferase 23
homeobox gene 23
phosphatidylinositol 3-kinase 22
FISH 22
bcr/abl 22
transcriptional regulator 22
SCL 22
granulocyte-macrophage colony-stimulating factor 22
threonine 22
IgG3 22
gag 21
CSF 21
IL-2 21
IDH2 21
HLA-DR 21
ABL1 21
megakaryocyte 21
G-CSF receptor 21
glycoprotein 20
transactivator 20
ASXL1 20
histone methyltransferase 20
H-ras 20
IKZF1 20
p30 20
CDKN2A 19
WT1) 19
GATA-1 19
leucine zipper 19
more...
Disease
leukemogenesis 4065
leukemia 2079
acute myeloid leukemia 1356
cancer 1204
tumor 614
acute lymphoblastic leukemia 534
Leukemia 390
lymphoma 292
chronic myeloid leukemia 276
myelodysplastic syndrome 251
acute leukemia 235
acute promyelocytic leukemia 173
myeloid leukemia 172
tumorigenesis 158
T-cell acute lymphoblastic leukemia 132
myeloproliferative disorders 116
ABL 114
lymphoblastic leukemia 108
PML 91
chronic lymphocytic leukemia 85
childhood ALL 79
hematologic malignancies 76
adult T-cell leukemia/lymphoma 75
chronic lymphocytic leukemia 74
carcinogenesis 73
B-ALL 66
Down syndrome 62
erythroleukemia 55
minimal residual disease 49
anemia 46
WT1 46
trisomy 45
SCID 37
MDS 36
blast crisis 34
chronic myelomonocytic leukemia 34
pediatric AML 32
bovine leukemia 31
tumor progression 29
HTLV-I 27
NOD 27
virus infection 26
neoplastic transformation 26
B-cell lymphoma 26
multiple myeloma 26
B-cell chronic lymphocytic leukemia 25
trisomy 8 25
juvenile myelomonocytic leukemia 24
Fanconi 23
sarcoma 23
Friend leukemia 23
Hodgkin's disease 23
childhood cancer 23
thrombocytopenia 22
adult AML 22
neutropenia 20
immunodeficiency 19
acute monocytic leukemia 19
severe congenital neutropenia 19
retinoblastoma 19
aplastic anemia 19
infectious diseases 18
DBA 18
secondary AML 18
tumor growth 17
Infection 17
ATM 16
radiation leukemia 16
eosinophilia 16
AIDS 15
lymphocytosis 15
megakaryocytic leukemia 15
APL 14
APL 14
HIV 14
acute nonlymphocytic leukemia 14
TMD 14
Epstein 14
APL 14
adult ALL 13
ARF 13
residual disease 13
dysplasia 13
FDC 13
aggressiveness 13
HAM 13
MCF 12
AML progression 12
depression 12
B-cell lymphomas 12
solid tumor 12
lymphosarcoma 12
non-Hodgkin's lymphoma 12
T-cell lymphoma 12
X-linked severe combined immunodeficiency 11
pancytopenia 11
carcinoma 11
breast cancer 11
myelopathy 10
Blocking 10
APC 9
Burkitt's lymphoma 9
lymphadenopathy 9
refractory anemia 9
FUS 8
viral leukemogenesis 8
T-cell lymphomas 8
LGL leukemia 8
rheumatoid arthritis 8
T-cell prolymphocytic leukemia 7
monocytic leukemia 7
melanoma 7
immune deficiency 7
cold 7
platelet disorder 7
multiple endocrine neoplasia 7
HCG 7
CAN 7
rare disease 6
metastases 6
PHA 6
polycythemia vera 6
Evans 6
acute undifferentiated leukemia 6
hepatocellular carcinoma 6
erythroblastosis 6
thymoma 6
Best 6
primary myelofibrosis 6
neuroblastoma 6
latent infection 6
chronic phase CML 6
lymphoproliferative disorders 6
SDS 6
lung cancer 6
viremia 5
plaque 5
thrombocytosis 5
glioblastoma 5
chronic leukemia 5
tumor initiation 5
CEM 5
MEN1 5
paroxysmal nocturnal hemoglobinuria 5
autoimmune disease 5
colon cancer 5
mammary tumor 5
HPC 5
Klippel-Trenaunay syndrome 5
neurofibromatosis 4
Leukemia stem cell 4
acute disease 4
primary tumor 4
Spleen 4
genetic disorder 4
osteosarcoma 4
HRS 4
CCD 4
uterus 4
FPD/AML 4
more...
Symptom
splenomegaly 31
hepatosplenomegaly 11
starvation 8
exhaustion 4
bone pain 2
hepatomegaly 2
headache 1
hypotonia 1
weakness 1
cachexia 1
erythema 1
ataxic gait 1
loss of balance 1
respiratory distress 1
overweight 1
dyspnea 1
fatigue 1
nasal congestion 1
Drug
TEL 66
lysine 62
CSF 42
MDS 36
ETS 25
Imatinib 24
IL-2 21
G-CSF 17
Gleevec 15
Retinoic acid 9
Arsenic trioxide 6
Etoposide 5
MAP 5
Mutagen 5
G418 4
MOF 4
DNase I 4
Asn 4
ROS 4
p75 4
IFN-gamma 4
Norplant 4
CTX 3
AraC 3
NADH 3
niacin 2
Dasatinib 2
Anagrelide 2
CDP 2
RFP 2
TAT 2
ARA-C 2
MRC 2
NVP 2
Anakinra 1
ADM 1
Angiotensin II 1
Dacogen 1
ascorbate 1
Mizoribine 1
Paraffin 1
Isotretinoin 1
Lestaurtinib 1
Midostaurin 1
CDX 1
CTA 1
ROC 1
Glutathione 1
Azacytidine 1
NBT 1
Leaf 1
AZT 1
ampicillin 1
BH4 1
Heme 1
Lovastatin 1
EML 1
DPA 1
Intron A 1
Florisil 1
Purvalanol 1
Monit 1
Methylcellulose 1
CAM 1
NH3 1
Intron A 1
ID2 1
RAL 1
CDX 1
Retinoic Acid 1
Intron A 1
Trib 1
Luteinizing 1
MDM 1
IL-1ra 1
IL-11 1
AZT 1
Alliance 1
ICI 1
Adriamycin 1
TAC 1
GEO 1
CCL 1
Enzyme
ERK 247
focal adhesion kinase 208
mitogen-activated protein kinase 93
reverse transcriptase 52
protein kinase 48
topoisomerase 34
luciferase 33
RNA polymerase 29
DNA methyltransferase 28
topoisomerase 28
MEK 27
proteasome 25
histone acetyltransferase 23
phosphatidylinositol 3-kinase 22
peroxidase 20
CD10 18
calcineurin 15
cdc2 15
caspase-3 15
CD13 13
transcriptase 13
demethylase 12
glutathione S-transferase 12
phosphoinositide 3-kinase 9
isocitrate dehydrogenase 9
isocitrate dehydrogenase 9
PARP 8
protein kinase C 8
protein phosphatase 2A 8
catalase 7
IKK 7
factor C 7
ATPase 6
GSK 6
alkaline phosphatase 6
Rex 6
lysozyme 6
MAP 5
endonuclease 5
PHD 5
neutrophil elastase 5
gamma-glutamyl transpeptidase 5
asparaginase 4
TdT 4
lactate dehydrogenase 4
caspase-9 4
NQO1 4
chloramphenicol acetyltransferase 4
thymidine kinase 3
APC 3
p100 3
hypoxanthine-guanine phosphoribosyltransferase 3
phospholipase C 3
TGT 3
P-glycoprotein 3
RNase 3
thiopurine methyltransferase 3
DNA polymerase 3
MIP 3
PDK1 3
adenylate cyclase 3
RNase 3
acid phosphatase 3
CDR 3
matrix metalloproteinase 2 3
matrix metalloproteinase 9 2
p80 2
NADPH oxidase 2
BMT 2
cathepsin G 2
aldehyde dehydrogenase 2
adenosine deaminase 2
caspase-6 2
elastase 2
CEP 2
ACS 2
aldehyde dehydrogenase 2
adenosine deaminase 2
NADPH oxidase 2
caspase-6 2
sphingosine kinase 2
TAT 2
aldehyde dehydrogenase 2
dihydrofolate reductase 2
Lys4 2
aldehyde dehydrogenase 2
glucose-6-phosphate dehydrogenase 2
lysine acetyltransferase 2
beta-galactosidase 2
farnesyltransferase 2
farnesyltransferase 2
CEP 2
collagenase 2
Thy1 2
aldehyde dehydrogenase 2
CPT 2
Protein 2 2
histone demethylase 2
soluble epoxide hydrolase 1
peroxiredoxin 1
acetylcholinesterase 1
N-acetylglucosaminyltransferase 1
ceruloplasmin 1
CGT 1
glutathione peroxidase 1
ACE 1
polo-like kinase 1 1
methylenetetrahydrofolate reductase 1
alpha-L-fucosidase 1
cholinesterase 1
xylose isomerase 1
deoxycytidine kinase 1
prenyltransferase 1
MEKK1 1
EC 4.4.1.5 1
phosphoglucose isomerase 1
caspase-1 1
alpha-L-fucosidase 1
polynucleotide kinase 1
renin 1
CYP3A4 1
AGT 1
AMP-activated protein kinase 1
ribonuclease 1
complex I 1
BAT 1
triphosphatase 1
PTPase 1
sphingomyelin synthase 1
oxidosqualene cyclase 1
trypsin 1
5'-nucleotidase 1
FAST 1
aspartate aminotransferase 1
guanylate cyclase 1
ribonuclease 1
glyceraldehyde-3-phosphate dehydrogenase 1
dihydrolipoamide succinyltransferase 1
neuraminidase 1
SLB 1
thrombin 1
TSA 1
MCS 1
GAS 1
CPT 1
proprotein convertase 1
IMP dehydrogenase 1
superoxide dismutase 1
Pla 1
CPT 1
glutamate synthase 1
S1 nuclease 1
alpha-L-fucosidase 1
STR 1
furin 1
phosphodiesterase 1
methionine adenosyltransferase 1
alanine aminotransferase 1
granzyme B 1
dUTPase 1
more...
Compound
DNA 672
Dec 263
tyrosine 128
Clin 124
retinoic acid 124
BCR 123
ABL 114
lysine 69
TEL 66
benzene 55
oxygen 38
serine 37
zinc 28
Benzene 27
acetate 26
threonine 26
tryptophan 22
DBA 20
calcium 18
arginine 18
MEK 17
SET 17
urea 17
ATP 16
hydroquinone 16
DBA 15
DBA 15
leucine 14
anthracene 13
Pac 12
cysteine 12
glucose 12
AMP 11
Histone 11
THP 10
THP 10
formaldehyde 10
hydroxyglutarate 10
NH2 9
phosphate 9
Ara-C 9
boron 9
sodium 9
Asp 8
TEM 8
GTP 8
Ara-C 8
methionine 7
isocitrate 7
VP-16 7
barium 7
formaldehyde 7
glutamine 7
TPA 7
CAN 7
TPA 7
phenol 7
CAT 6
proline 6
NADPH 6
aspartic acid 6
2-oxoglutarate 6
CAT 6
PAC 6
aspartic acid 6
aspartic acid 6
TNF 6
NADPH 6
alanine 6
iron 6
aspartic acid 6
DEK 6
CAT 6
His 6
TET 5
cAMP 5
Cbl 5
5-Aza-2'-deoxycytidine 5
HPC 5
TET 5
GSH 5
water 5
KTS 5
MAP 5
GSH 5
HPC 5
Phe 4
aldehyde 4
iodine 4
MAL 4
NAD 4
NAD 4
Gly 4
aldehyde 4
Optimal 4
MTT 4
CAM 4
DMSO 3
Valproic acid 3
COS 3
sulfate 3
Glycogen synthase 3
NFS 3
MNU 3
uridine 3
tryptophan 3
Hydroxyurea 3
hydrogen 3
DFS 3
Valproic acid 3
E-4031 3
ADP 3
ADP 3
TGT 3
tryptophan 3
ADP 3
NADH 3
CAA 3
CTX 3
adenylate 3
tryptophan 3
Calcitonin 2
HCP 2
creatinine 2
ACS 2
Guo 2
adenosylmethionine 2
Insulin 2
ammonia 2
SC-1 2
acetyl-CoA 2
Tyrosine 2
PMA 2
glutamic acid 2
nicotinamide 2
Ubiquitin 2
APO 2
Methotrexate 2
ENU 2
ACS 2
Serine 2
PMA 2
CHIP 2
1,3-Butadiene 2
HCP 2
T11 2
copper 2
palmitic acid 2
CoA 2
MCA 2
Ribavirin 2
GMP 2
PCI 2
bromide 2
SC-1 2
5-FU 2
ETH 2
salt 2
PNA 2
1,2,4-benzenetriol 2
more...