Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0596978 (Leukemia)
15,069 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 962
lymphoid 601
AML 538
CD34 402
cytokine 381
p53 365
BCR 360
ALL 340
ABL 338
tyrosine kinase 323
erythroid 289
MLL 227
interferon 220
FLT3 208
non-Hodgkin's lymphoma 203
all-trans 201
HLA 196
FAB 187
IL-3 185
CML 175
CD4 171
Bcl-2 166
CD19 163
CD38 162
GM-CSF 160
granulocyte 147
CD8 145
G-CSF 144
CD33 140
IL-6 139
JAK2 137
IFN 136
granulocyte colony-stimulating factor 133
P-glycoprotein 131
CD10 127
CSF 124
granulocyte-macrophage colony-stimulating factor 124
p13 122
hemoglobin 116
histone 116
PML 116
caspase-3 115
AML1 115
bcr 113
CLL 112
IgG3 109
Mol 109
T cell receptor 107
TEL 107
CD5 103
RUNX1 102
CD20 100
MDS 100
tumor necrosis factor 100
thymus 99
IL-2 98
ara 97
granulocyte-macrophage 96
bcl-2 95
erythropoietin 93
MYC 93
p21 93
AKT 92
STAT 90
c-fms 90
CD7 89
FISH 89
proto-oncogene 88
c-myc 87
BCL2 87
interleukin-2 86
HLA-DR 86
PI3K 85
BCR/ABL 85
macrophage colony-stimulating factor 83
mTOR 82
CD13 81
proteasome 80
ERK 80
NOD 79
more...
Disease
Leukemia 15069
leukemia 14593
acute myeloid leukemia 2450
cancer 2382
tumor 1432
acute lymphoblastic leukemia 1377
chronic myeloid leukemia 896
lymphoma 848
multiple myeloma 736
myelodysplastic syndrome 724
chronic lymphocytic leukemia 625
chronic lymphocytic leukemia 513
acute leukemia 430
leukemogenesis 390
minimal residual disease 383
acute promyelocytic leukemia 360
ABL 338
Hodgkin's disease 303
T-cell acute lymphoblastic leukemia 260
non-Hodgkin's lymphoma 242
childhood ALL 231
myeloid leukemia 223
graft-versus-host disease 208
blast crisis 170
B-cell lymphoma 168
lymphoblastic leukemia 164
anemia 160
myeloproliferative disorders 158
hematologic malignancies 158
thrombocytopenia 147
B-ALL 145
tumorigenesis 141
neutropenia 141
B-cell chronic lymphocytic leukemia 140
SCID 131
residual disease 129
tumor growth 121
hairy cell leukemia 121
PML 117
breast cancer 112
HIV 106
trisomy 102
Epstein 101
MDS 100
chronic myelomonocytic leukemia 93
follicular lymphoma 93
mantle cell lymphoma 83
adult T-cell leukemia/lymphoma 82
essential thrombocythemia 82
carcinoma 82
WT1 80
refractory anemia 80
NOD 79
polycythemia vera 78
Burkitt's lymphoma 78
primary myelofibrosis 77
sarcoma 75
erythroleukemia 75
adult ALL 72
acute nonlymphocytic leukemia 70
Down syndrome 69
secondary AML 69
lymphoproliferative disorders 67
HTLV-I 66
pediatric AML 66
immunodeficiency 65
melanoma 65
myelofibrosis 65
myelosuppression 64
tumor progression 64
CEM 63
adult AML 62
lung cancer 61
SCT 55
B-cell lymphomas 55
trisomy 8 54
AIDS 54
Infection 52
lymphadenopathy 51
lymphocytosis 50
more...
Symptom
splenomegaly 99
fatigue 45
diarrhea 44
nausea 37
vomiting 31
exhaustion 26
nausea and vomiting 22
hepatosplenomegaly 20
pain 20
hepatomegaly 17
headache 14
starvation 13
bone pain 11
abdominal pain 10
weakness 7
seizures 7
dyspnea 7
anorexia 7
sleepiness 6
respiratory distress 5
discomfort 5
fever of unknown origin 5
collapse 5
discomfort 5
tremor 4
pallor 4
dry skin 4
lethargy 4
paresthesia 3
paresis 3
chest pain 3
arthralgia 3
HSA 3
erythema 3
constipation 3
chills 3
cough 3
vertigo 3
dizziness 3
myalgia 2
cerebellar ataxia 2
Ill 2
functional recovery 2
anesthesia 2
overweight 2
paraparesis 2
blurred vision 2
decreased appetite 2
cachexia 2
dysarthria 2
syncope 2
ENT 2
dysuria 1
tachypnea 1
otalgia 1
emaciation 1
ataxia 1
flank pain 1
intestinal bleeding 1
hyperemesis 1
spasticity 1
acidity 1
back pain 1
chorea 1
thinning 1
chromosome marker 1
shortness of breath 1
agitation 1
night sweats 1
photophobia 1
Roth spots 1
Decreased activity 1
Spotting 1
low back pain 1
autodigestion 1
dry eye 1
acute stress 1
non-productive cough 1
Drug
CSF 256
G-CSF 144
MDS 100
IL-2 99
Imatinib 67
TEL 66
lysine 61
IFN-gamma 53
Leaf 35
Gleevec 34
Bortezomib 29
Fludarabine 27
anti-CD33 24
IL-11 22
Adriamycin 22
-deoxyadenosine 20
ROS 19
Rituximab 19
AraC 19
Alliance 19
ETS 18
CTX 18
MRC 17
Lenalidomide 16
Retinoic acid 15
G418 14
Arsenic trioxide 14
Taxol 13
MAP 12
Idarubicin 12
p75 11
AZT 11
Campath 11
ADR 11
DNase I 11
AZT 11
Campath 11
Dasatinib 10
ABC 9
VCR 9
Glutathione 9
ARA-C 9
Sorafenib 9
VCR 8
Vinorelbine 8
ADM 8
Asparaginase 8
Navelbine 7
Docetaxel 7
Etoposide 7
Taxotere 7
NVP 7
CTX 6
THF 6
caffeine 6
CTX 6
TRM 6
Gel 6
Dermatol 6
Lovastatin 6
NBT 5
CTC 5
L-Asparaginase 5
Midostaurin 5
ENT 5
Indomethacin 5
CTC 5
Prednisolone 5
TTC 4
Rasburicase 4
Monit 4
TAK 4
Retinoic Acid 4
IFN-beta 4
Amifostine 4
Isotretinoin 4
Filgrastim 4
vitamin E 4
Filgrastim 4
Paraffin 4
more...
Enzyme
focal adhesion kinase 605
ERK 464
mitogen-activated protein kinase 177
reverse transcriptase 144
P-glycoprotein 132
CD10 129
protein kinase 98
asparaginase 94
caspase-3 94
peroxidase 92
topoisomerase 83
CD13 81
MEK 80
proteasome 80
topoisomerase 73
BMT 56
protein kinase C 51
TdT 44
lactate dehydrogenase 44
PARP 43
RNA polymerase 41
DNA methyltransferase 33
caspase-8 32
caspase-9 32
alkaline phosphatase 31
RNase 26
cdc2 25
dihydrofolate reductase 25
RNase 25
phosphoinositide 3-kinase 23
transcriptase 23
DNA polymerase 23
MDR 21
thymidine kinase 21
luciferase 21
phosphatidylinositol 3-kinase 20
deoxycytidine kinase 20
calcineurin 19
trypsin 18
thymidylate synthase 18
catalase 18
endonuclease 17
lysozyme 16
ATPase 16
ricin 15
glutathione S-transferase 15
ribonucleotide reductase 15
phosphoglycerate kinase 15
ribonucleotide reductase 15
phospholipase C 14
acid phosphatase 13
thyroid peroxidase 13
caspase-1 13
APC 12
AMP-activated protein kinase 12
cytidine deaminase 12
adenosine deaminase 11
beta-galactosidase 11
superoxide dismutase 11
adenosine deaminase 11
TSA 11
glyceraldehyde-3-phosphate dehydrogenase 10
MAP 10
demethylase 10
granzyme B 10
DNase 9
ornithine decarboxylase 9
AMPK 9
isocitrate dehydrogenase 8
NOS 8
protein phosphatase 2A 8
thiopurine methyltransferase 8
Rex 8
plasmin 8
isocitrate dehydrogenase 8
AMPK 8
histone acetyltransferase 8
GSK 8
STR 8
thrombin 8
more...
Compound
DNA 1341
Dec 1043
BCR 360
ABL 338
retinoic acid 318
tyrosine 201
Clin 167
Ara-C 132
oxygen 120
Ara-C 115
acetate 108
lysine 79
TNF 71
TEL 66
ATP 66
serine 66
calcium 64
MTT 64
MEK 61
sodium 52
phosphate 47
tryptophan 45
leucine 43
VP-16 42
Methotrexate 41
glucose 40
water 40
boron 39
iron 38
threonine 37
DBA 37
DBA 36
DBA 36
TPA 35
TPA 35
Adriamycin 35
arginine 33
pyrimidine 32
methionine 32
cysteine 32
zinc 32
pyrimidine 32
THP 31
THP 31
iodine 30
DMSO 30
sulfate 29
DFS 29
MTX 27
Asp 27
GSH 26
benzene 26
CTP 26
GSH 26
AMP 24
PMA 23
PMA 23
uridine 23
alanine 23
ADR 23
Phe 22
MDR 21
LTC4 21
creatinine 20
His 20
nitric oxide 20
5-Aza-2'-deoxycytidine 19
CTX 18
bromide 18
cAMP 17
nitrogen 17
vitamin D 16
DDP 16
tryptophan 16
tryptophan 16
SDS 16
tryptophan 16
urea 16
asparagine 16
SET 16
more...