Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

---

Query: UMLS:C0596978 (Leukemia)
15,069 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein Sep 962 lymphoid 601 AML 538 CD34 402 cytokine 381 p53 365 BCR 360 ALL 340 ABL 338 tyrosine kinase 323 erythroid 289 MLL 227 interferon 220 FLT3 208 non-Hodgkin's lymphoma 203 all-trans 201 HLA 196 FAB 187 IL-3 185 CML 175 CD4 171 Bcl-2 166 CD19 163 CD38 162 GM-CSF 160 granulocyte 147 CD8 145 G-CSF 144 CD33 140 IL-6 139 JAK2 137 IFN 136 granulocyte colony-stimulating factor 133 P-glycoprotein 131 CD10 127 granulocyte-macrophage colony-stimulating factor 124 CSF 124 p13 122 PML 116 histone 116 more...

Disease Leukemia 15069 leukemia 14593 acute myeloid leukemia 2450 cancer 2382 tumor 1432 acute lymphoblastic leukemia 1377 chronic myeloid leukemia 896 lymphoma 848 multiple myeloma 736 myelodysplastic syndrome 724 chronic lymphocytic leukemia 625 chronic lymphocytic leukemia 513 acute leukemia 430 leukemogenesis 390 minimal residual disease 383 acute promyelocytic leukemia 360 ABL 338 Hodgkin's disease 303 T-cell acute lymphoblastic leukemia 260 non-Hodgkin's lymphoma 242 childhood ALL 231 myeloid leukemia 223 graft-versus-host disease 208 blast crisis 170 B-cell lymphoma 168 lymphoblastic leukemia 164 anemia 160 myeloproliferative disorders 158 hematologic malignancies 158 thrombocytopenia 147 B-ALL 145 neutropenia 141 tumorigenesis 141 B-cell chronic lymphocytic leukemia 140 SCID 131 residual disease 129 tumor growth 121 hairy cell leukemia 121 PML 117 breast cancer 112 more...

Symptom splenomegaly 99 fatigue 45 diarrhea 44 nausea 37 vomiting 31 exhaustion 26 nausea and vomiting 22 pain 20 hepatosplenomegaly 20 hepatomegaly 17 headache 14 starvation 13 bone pain 11 abdominal pain 10 seizures 7 anorexia 7 dyspnea 7 weakness 7 sleepiness 6 collapse 5 discomfort 5 fever of unknown origin 5 discomfort 5 respiratory distress 5 pallor 4 tremor 4 lethargy 4 dry skin 4 arthralgia 3 paresthesia 3 dizziness 3 constipation 3 chills 3 paresis 3 cough 3 chest pain 3 HSA 3 erythema 3 vertigo 3 myalgia 2 more...

Drug CSF 256 G-CSF 144 MDS 100 IL-2 99 Imatinib 67 TEL 66 lysine 61 IFN-gamma 53 Leaf 35 Gleevec 34 Bortezomib 29 Fludarabine 27 anti-CD33 24 IL-11 22 Adriamycin 22 -deoxyadenosine 20 Rituximab 19 AraC 19 Alliance 19 ROS 19 CTX 18 ETS 18 MRC 17 Lenalidomide 16 Retinoic acid 15 Arsenic trioxide 14 G418 14 Taxol 13 MAP 12 Idarubicin 12 Campath 11 p75 11 AZT 11 Campath 11 ADR 11 AZT 11 DNase I 11 Dasatinib 10 Sorafenib 9 Glutathione 9 more...

Enzyme focal adhesion kinase 605 ERK 464 mitogen-activated protein kinase 177 reverse transcriptase 144 P-glycoprotein 132 CD10 129 protein kinase 98 asparaginase 94 caspase-3 94 peroxidase 92 topoisomerase 83 CD13 81 proteasome 80 MEK 80 topoisomerase 73 BMT 56 protein kinase C 51 TdT 44 lactate dehydrogenase 44 PARP 43 RNA polymerase 41 DNA methyltransferase 33 caspase-8 32 caspase-9 32 alkaline phosphatase 31 RNase 26 cdc2 25 RNase 25 dihydrofolate reductase 25 phosphoinositide 3-kinase 23 DNA polymerase 23 transcriptase 23 MDR 21 thymidine kinase 21 luciferase 21 phosphatidylinositol 3-kinase 20 deoxycytidine kinase 20 calcineurin 19 trypsin 18 thymidylate synthase 18 more...

Compound DNA 1341 Dec 1043 BCR 360 ABL 338 retinoic acid 318 tyrosine 201 Clin 167 Ara-C 132 oxygen 120 Ara-C 115 acetate 108 lysine 79 TNF 71 ATP 66 TEL 66 serine 66 calcium 64 MTT 64 MEK 61 sodium 52 phosphate 47 tryptophan 45 leucine 43 VP-16 42 Methotrexate 41 glucose 40 water 40 boron 39 iron 38 DBA 37 threonine 37 DBA 36 DBA 36 TPA 35 TPA 35 Adriamycin 35 arginine 33 zinc 32 pyrimidine 32 methionine 32 more...

---