Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0596263 (carcinogenesis)
 64,820 document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
p53 4750
Sep 4288
Mol 3813
ras 1027
histone 960
cyclin D1 897
p21 892
cyclooxygenase-2 859
catenin 840
cytokine 817
glutathione S-transferase 768
estrogen receptor 741
E-cadherin 720
insulin 698
beta-catenin 686
proliferating cell nuclear antigen 683
COX-2 667
p16 664
epidermal growth factor receptor 651
AKT 651
microsomal 631
Bcl-2 611
caspase-3 590
cytochrome P450 585
catalase 562
ornithine decarboxylase 550
PI3K 538
GSH 529
K-ras 519
mTOR 515
vascular endothelial growth factor 496
superoxide dismutase 492
APC 490
MAPK 489
c-myc 485
tumour suppressor 478
gut 472
Ki-67 446
thymus 443
tumor necrosis factor 431
GST 428
cage 427
cyclooxygenase 424
ERK 417
PTEN 394
p38 392
EGFR 384
xenobiotic 383
epidermal growth factor 378
inducible nitric oxide synthase 374
KRAS 373
CYP1A1 370
TNF 369
IL-6 362
tyrosine kinase 356
androgen receptor 351
BRCA1 342
ERK1 339
collagen 337
lymphoid 333
glutathione peroxidase 333
c-Myc 332
TNM 330
STAT3 328
p27 327
proto-oncogene 326
UTR 326
cytochrome 314
ubiquitin 304
AP-1 302
BRAF 302
mucin 299
H-ras 297
ATP 293
P450 291
HER2 290
TPA 289
matrix metalloproteinase 288
TGF-beta 283
c-Jun 282
more...
Disease
carcinogenesis 64820
cancer 30464
tumor 21494
carcinoma 5623
tumorigenesis 4964
breast cancer 4139
colorectal cancer 3501
tumor progression 2891
hepatocellular carcinoma 2821
lung cancer 2705
adenocarcinoma 2699
squamous cell carcinoma 2480
gastric cancer 2401
colon cancer 2325
tumor growth 1918
prostate cancer 1908
dysplasia 1514
adenoma 1266
metastases 1246
cervical cancer 1220
skin cancer 1049
pancreatic cancer 888
bladder cancer 842
melanoma 833
liver cancer 801
ovarian cancer 749
obesity 659
leukemia 657
neoplastic transformation 652
liver cancer 647
MCF 608
papilloma 607
endometrial cancer 559
hepatitis B 537
non-small cell lung cancer 532
GSH 529
oral cancer 517
chemical carcinogenesis 503
cirrhosis 496
APC 493
skin tumor 488
Epstein 483
renal cell carcinoma 471
lymphoma 464
diabetes 460
esophageal cancer 459
colitis 439
gastritis 428
mammary tumor 423
esophageal cancer 417
tumor initiation 413
retinoblastoma 396
lung carcinoma 393
Hepatocellular carcinoma 381
aggressiveness 361
epithelial ovarian cancer 345
carcinoma in situ 319
primary tumor 313
cervical intraepithelial neoplasia 303
glioma 302
familial adenomatous polyposis 301
Helicobacter pylori infection 301
thyroid cancer 295
Barrett's esophagus 293
xeroderma pigmentosum 271
inflammatory bowel disease 270
ulcerative colitis 263
hepatitis C 258
AIN 256
virus infection 252
atrophic gastritis 248
head and neck cancer 235
sarcoma 234
invasive cancer 230
ATM 225
uterine cervix 218
infectious diseases 213
osteosarcoma 212
basal cell carcinoma 210
uterus 209
more...
Symptom
erythema 88
starvation 75
pain 75
overweight 59
diarrhea 59
hepatomegaly 49
skin damage 46
abdominal pain 26
acidity 26
anesthesia 26
cachexia 23
weakness 21
exhaustion 20
seizures 17
collapse 16
fatigue 16
skin irritant 15
hyperoxia 15
splenomegaly 14
lethargy 14
nausea 13
anorexia 12
thinning 11
dyspnea 11
ataxia 11
vomiting 11
constipation 11
headache 10
skin irritation 10
cough 10
flushing 9
ENT 8
regurgitation 8
analgesia 8
menopausal symptoms 8
respiratory distress 7
discomfort 7
Ill 7
discomfort 7
tremor 7
colic 6
chest pain 5
cancer pain 5
Fluctuation 5
hypothermia 5
microbial colonization 5
prostration 4
Spots 4
dizziness 4
back pain 4
epigastric pain 4
myalgia 3
peri-menopausal 3
Wind 3
angina 3
HSA 3
arthralgia 3
bloating 3
rhinorrhea 3
DNA marker 3
dry skin 3
hunger 3
nausea and vomiting 3
intestinal bleeding 3
paresis 2
heartburn 2
hoarseness 2
stigma 2
scaly skin 2
polydipsia 2
chronic constipation 2
hot flashes 2
halitosis 2
disturbed balance 2
productive cough 2
emaciation 2
bitter taste 2
loss of balance 2
acute stress 2
sleepiness 2
more...
Drug
Dermatol 484
ascorbate 366
lysine 315
vitamin E 267
Mutagen 253
ROS 211
caffeine 148
NADH 111
Glutathione 109
MAP 92
Estrogens 79
EE2 65
IFN-gamma 62
Retinoic acid 60
ICI 55
Paraffin 50
Vitamin A 50
Ethanol 49
PTC 48
GEO 48
IL-2 47
-deoxyadenosine 45
Vitamin E 44
Monit 44
EPA 42
Arsenic trioxide 41
Gel 41
ETS 41
Asn 41
Bifidobacterium 41
ABC 39
Indomethacin 38
G418 35
CTA 33
MRC 33
Leaf 28
ROC 28
DNase I 27
niacin 26
CAM 25
Heme 25
Sorafenib 24
Cardiovasc 24
PCB 24
uPA 22
CSF 21
Nitric Oxide 19
BLM 19
THF 19
Herceptin 18
Gefitinib 18
Areca 17
Taxol 17
ENT 17
Tocopherol 16
Fraction 16
Imatinib 16
lactose 16
CTX 16
Activin 16
Dihydro 14
Cetuximab 14
Albumin 13
AGG 13
Aloe 13
Furan 13
VCR 12
Adriamycin 12
G-CSF 11
Bevacizumab 11
TiO2 11
Epigallocatechin 11
R1881 11
FAD 11
HCH 10
Ciprofibrate 10
Angiotensin II 10
IL-1ra 10
Myricetin 10
linolenate 10
more...
Enzyme
ERK 1584
mitogen-activated protein kinase 1484
glutathione S-transferase 1040
luciferase 751
protein kinase 645
catalase 637
superoxide dismutase 563
ornithine decarboxylase 550
protein kinase C 509
APC 495
gamma-glutamyl transpeptidase 461
caspase-3 432
focal adhesion kinase 417
glutathione peroxidase 347
MEK 318
peroxidase 307
NQO1 295
reverse transcriptase 280
proteasome 271
DNA methyltransferase 260
PARP 244
DNA polymerase 212
ATPase 196
cdc2 181
phosphatidylinositol 3-kinase 181
alkaline phosphatase 142
endonuclease 141
glutathione reductase 133
RNA polymerase 132
lipoxygenase 128
GSK 126
alanine aminotransferase 119
aldehyde dehydrogenase 115
AMP-activated protein kinase 113
demethylase 113
aldehyde dehydrogenase 112
collagenase 109
soluble epoxide hydrolase 109
caspase-9 108
prostate-specific antigen 108
aldehyde dehydrogenase 105
aldehyde dehydrogenase 105
aldehyde dehydrogenase 105
lactate dehydrogenase 95
topoisomerase 94
beta-glucuronidase 94
caspase-8 92
UDP-glucuronosyltransferase 92
urokinase-type plasminogen activator 92
glucose-6-phosphate dehydrogenase 92
hypoxanthine-guanine phosphoribosyltransferase 91
aryl hydrocarbon hydroxylase 84
aspartate aminotransferase 84
N-acetyltransferase 84
phosphoinositide 3-kinase 83
MMP 81
trypsin 81
topoisomerase 80
IKK 78
alcohol dehydrogenase 77
NO synthase 76
microsomal epoxide hydrolase 75
xanthine oxidase 74
NADPH oxidase 73
AMPK 71
NADPH oxidase 70
phospholipase A2 69
glucose-6-phosphatase 68
calcineurin 66
P-glycoprotein 65
RNase 65
RNase 65
thymidine kinase 65
PAH 65
DNA ligase 60
DNA ligase 60
AMPK 58
CYP3A4 57
methylenetetrahydrofolate reductase 56
methylenetetrahydrofolate reductase 56
more...
Compound
DNA 15332
Dec 4543
oxygen 2393
water 2113
acetate 1969
Clin 1922
anthracene 1789
pyrene 1582
sodium 1216
DBA 802
calcium 769
GSH 621
GSH 621
sulfate 585
iron 575
1,2-dimethylhydrazine 560
hydrogen 553
tyrosine 532
glucose 504
retinoic acid 502
ethanol 483
nitric oxide 481
selenium 464
phosphate 462
cysteine 450
aflatoxin B1 437
methionine 433
lysine 398
MDA 371
TNF 369
nitrogen 360
pyridine 353
H2O2 349
TNM 331
arginine 330
serine 329
zinc 324
8-OHdG 308
MTT 300
TPA 296
ATP 294
TPA 289
nickel 285
copper 275
aldehyde 267
Pac 265
NADPH 261
chromium 261
NADPH 261
pyrimidine 258
pyrimidine 257
vitamin D 249
acetone 247
threonine 241
Estrogen 232
DEN 232
cadmium 228
salt 225
quinoline 223
quinoline 222
Estrogen 221
PGE 211
MEK 211
NAD 211
AAF 205
Curcumin 205
urea 205
His 197
benzene 194
Arsenic 192
retinol 184
PGE2 175
N-acetylcysteine 174
formaldehyde 167
ADP 166
BOP 164
NAD 164
acetaldehyde 161
alanine 156
nitrate 152
more...