Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0596263 (
carcinogenesis
)
64,820
document(s) hit in 31,850,051 MEDLINE articles (0.05 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
p53
4750
Sep
4288
Mol
3813
ras
1027
histone
960
cyclin D1
897
p21
892
cyclooxygenase-2
859
catenin
840
cytokine
817
glutathione S-transferase
768
estrogen receptor
741
E-cadherin
720
insulin
698
beta-catenin
686
proliferating cell nuclear antigen
683
COX-2
667
p16
664
epidermal growth factor receptor
651
AKT
651
microsomal
631
Bcl-2
611
caspase-3
590
cytochrome P450
585
catalase
562
ornithine decarboxylase
550
PI3K
538
GSH
529
K-ras
519
mTOR
515
vascular endothelial growth factor
496
superoxide dismutase
492
APC
490
MAPK
489
c-myc
485
tumour suppressor
478
gut
472
Ki-67
446
thymus
443
tumor necrosis factor
431
more...
Disease
carcinogenesis
64820
cancer
30464
tumor
21494
carcinoma
5623
tumorigenesis
4964
breast cancer
4139
colorectal cancer
3501
tumor progression
2891
hepatocellular carcinoma
2821
lung cancer
2705
adenocarcinoma
2699
squamous cell carcinoma
2480
gastric cancer
2401
colon cancer
2325
tumor growth
1918
prostate cancer
1908
dysplasia
1514
adenoma
1266
metastases
1246
cervical cancer
1220
skin cancer
1049
pancreatic cancer
888
bladder cancer
842
melanoma
833
liver cancer
801
ovarian cancer
749
obesity
659
leukemia
657
neoplastic transformation
652
liver cancer
647
MCF
608
papilloma
607
endometrial cancer
559
hepatitis B
537
non-small cell lung cancer
532
GSH
529
oral cancer
517
chemical carcinogenesis
503
cirrhosis
496
APC
493
more...
Symptom
erythema
88
pain
75
starvation
75
overweight
59
diarrhea
59
hepatomegaly
49
skin damage
46
anesthesia
26
abdominal pain
26
acidity
26
cachexia
23
weakness
21
exhaustion
20
seizures
17
fatigue
16
collapse
16
skin irritant
15
hyperoxia
15
lethargy
14
splenomegaly
14
nausea
13
anorexia
12
dyspnea
11
vomiting
11
ataxia
11
thinning
11
constipation
11
headache
10
cough
10
skin irritation
10
flushing
9
analgesia
8
regurgitation
8
ENT
8
menopausal symptoms
8
Ill
7
respiratory distress
7
discomfort
7
tremor
7
discomfort
7
more...
Drug
Dermatol
484
ascorbate
366
lysine
315
vitamin E
267
Mutagen
253
ROS
211
caffeine
148
NADH
111
Glutathione
109
MAP
92
Estrogens
79
EE2
65
IFN-gamma
62
Retinoic acid
60
ICI
55
Paraffin
50
Vitamin A
50
Ethanol
49
GEO
48
PTC
48
IL-2
47
-deoxyadenosine
45
Monit
44
Vitamin E
44
EPA
42
Bifidobacterium
41
Asn
41
Arsenic trioxide
41
Gel
41
ETS
41
ABC
39
Indomethacin
38
G418
35
CTA
33
MRC
33
Leaf
28
ROC
28
DNase I
27
niacin
26
Heme
25
more...
Enzyme
ERK
1584
mitogen-activated protein kinase
1484
glutathione S-transferase
1040
luciferase
751
protein kinase
645
catalase
637
superoxide dismutase
563
ornithine decarboxylase
550
protein kinase C
509
APC
495
gamma-glutamyl transpeptidase
461
caspase-3
432
focal adhesion kinase
417
glutathione peroxidase
347
MEK
318
peroxidase
307
NQO1
295
reverse transcriptase
280
proteasome
271
DNA methyltransferase
260
PARP
244
DNA polymerase
212
ATPase
196
phosphatidylinositol 3-kinase
181
cdc2
181
alkaline phosphatase
142
endonuclease
141
glutathione reductase
133
RNA polymerase
132
lipoxygenase
128
GSK
126
alanine aminotransferase
119
aldehyde dehydrogenase
115
demethylase
113
AMP-activated protein kinase
113
aldehyde dehydrogenase
112
collagenase
109
soluble epoxide hydrolase
109
prostate-specific antigen
108
caspase-9
108
more...
Compound
DNA
15332
Dec
4543
oxygen
2393
water
2113
acetate
1969
Clin
1922
anthracene
1789
pyrene
1582
sodium
1216
DBA
802
calcium
769
GSH
621
GSH
621
sulfate
585
iron
575
1,2-dimethylhydrazine
560
hydrogen
553
tyrosine
532
glucose
504
retinoic acid
502
ethanol
483
nitric oxide
481
selenium
464
phosphate
462
cysteine
450
aflatoxin B1
437
methionine
433
lysine
398
MDA
371
TNF
369
nitrogen
360
pyridine
353
H2O2
349
TNM
331
arginine
330
serine
329
zinc
324
8-OHdG
308
MTT
300
TPA
296
more...