Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0596240 (cancer pain)
 3,066 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 189
opioid receptor 77
Mol 31
Walker 24
cage 22
cytokine 16
She 15
CSF 14
OPRM1 14
nerve growth factor 13
ATP 13
calcitonin 13
NMDA receptor 13
endothelin-1 13
CB2 12
TNF 12
CB1 11
TRPV1 11
beta-endorphin 11
osteosarcoma 10
substance P 10
glial fibrillary acidic protein 10
cannabinoid receptor 9
reserved 9
COMT 8
cyclooxygenase-2 8
TLR4 8
ABCB1 8
CYP2D6 8
dynorphin 8
calcium channel 8
P2X 8
BPI 7
IL-6 7
COX-2 7
PRN 7
delta opioid receptor 7
THC 7
short form 7
mu opioid receptor 7
cytochrome P450 6
CGRP 6
chemokine 6
MSC 6
somatostatin 6
MST 5
neurotrophin 5
tyrosine kinase 5
P2X3 5
kappa opioid receptor 5
Met 5
tumor necrosis factor 5
gut 4
tropomyosin 4
cyclooxygenase 4
IL-1 4
receptor kinase 4
epidermal growth factor receptor 4
ERK 4
F10 4
C30 4
NGF 4
ARRB2 4
AKT 4
vascular endothelial growth factor 4
PCA 4
cholecystokinin 4
P2X7 4
P-glycoprotein 4
sodium channel 4
CCL2 4
GABA 3
ETA 3
CXCL10 3
Endothelin-1 3
CYP3A4 3
COX-1 3
serine protease 3
P450 3
ATC 3
more...
Disease
cancer 1631
chronic pain 437
tumor 244
addiction 168
depression 167
metastases 94
bone cancer 83
breast cancer 53
carcinoma 48
bone metastases 42
tumor growth 40
lung cancer 34
osteoarthritis 30
psychological distress 28
pruritus 28
celiac disease 26
pancreatic cancer 26
melanoma 25
cognitive impairment 24
migraine 24
rheumatoid arthritis 23
postherpetic neuralgia 22
prostate cancer 22
arthritis 22
refractory cancer 21
Frey 21
delirium 21
confusion 20
substance abuse 19
xerostomia 19
multiple sclerosis 19
physical dependence 19
hallucinations 18
squamous cell carcinoma 18
fibrosarcoma 18
fibromyalgia 18
tumor progression 18
peripheral neuropathy 18
drug addiction 17
drug abuse 16
trigeminal neuralgia 16
spinal cord compression 16
Best 15
HIV 14
herpes zoster 14
diabetic neuropathy 13
cold 13
AIDS 13
Cannabis 13
adenocarcinoma 12
osteosarcoma 12
renal failure 12
childhood cancer 12
dysphagia 12
diabetes 11
oral cancer 11
West 11
rectal cancer 11
neuropathy 11
sarcoma 11
primary tumor 10
head and neck cancer 10
regional pain syndrome 10
stroke 10
substance use 10
meningitis 9
emotional distress 9
phantom limb pain 9
epilepsy 8
bowel obstruction 8
hepatocellular carcinoma 8
sleep disturbances 8
Alzheimer's disease 7
THC 7
substance use disorders 7
chronic disease 7
multiple myeloma 7
sexual dysfunction 7
non-small cell lung cancer 7
tumorigenesis 7
more...
Symptom
cancer pain 3066
pain 2630
analgesia 461
constipation 155
nausea 142
breakthrough pain 131
acute pain 92
headache 91
vomiting 88
bone pain 68
sleepiness 62
anesthesia 57
nausea and vomiting 50
fatigue 43
low back pain 36
Neuropathic pain 30
dizziness 29
back pain 26
abdominal pain 24
anorexia 24
dyspnea 22
spasticity 19
myoclonus 17
discomfort 16
cachexia 15
discomfort 15
insomnia 15
erythema 12
diarrhea 12
neuralgia 11
arthralgia 10
weakness 9
facial pain 9
chest pain 8
distraction 7
seizures 7
orofacial pain 7
agitation 7
stigma 7
Sedation 6
chronic back pain 6
pelvic pain 6
neck pain 5
ataxia 5
vertigo 4
myalgia 4
leg pain 4
stump pain 3
Severe pain 3
PAIN 3
hypothermia 3
hot flashes 3
tingling 3
limb pain 3
Ill 3
arm pain 3
spasm 3
Postoperative pain 3
paresis 3
paresthesia 3
acidity 3
blurred vision 3
cough 3
asthenia 3
numbness 3
exhaustion 2
shoulder pain 2
abdominal fullness 2
incoordination 2
tenesmus 2
forgetfulness 2
hopelessness 2
shortness of breath 2
alexithymia 2
dysesthesia 2
angina 2
tinnitus 2
dysuria 2
tremor 2
bradypnea 2
more...
Drug
Fentanyl 57
CSF 16
Monit 10
Clonidine 8
9-THC 7
Gabapentin 7
Codeine 7
Codeine 7
Morphine sulfate 5
Ketorolac 4
Tramal 4
Tapentadol 4
Nabilone 3
Donepezil 3
Cardiovasc 3
Meconium 3
Meth 3
Tramadol hydrochloride 3
Ziconotide 3
Check 3
Oxycontin 2
Ketorolac tromethamine 2
ENT 2
G-CSF 2
Indomethacin 2
Oxycon 2
Subutex 2
Pregabalin 2
Opium 2
Bayer 2
Bupivacaine 2
lysine 2
BH4 2
caffeine 2
p75 2
SrCl2 2
ETA 2
Pirprofen 1
EE2 1
Rimonabant 1
Dermatol 1
Limaprost 1
Fentanyl citrate 1
Apomorphine 1
FLP 1
Tora 1
Contomin 1
Propentofylline 1
IFN-gamma 1
Ritalin 1
ascorbate 1
Salmon calcitonin 1
Triad 1
Dextropropoxyphene 1
Asn 1
Ranitidine 1
Dipyrone 1
Percocet 1
Glycyrrhiza 1
Denosumab 1
CCL 1
Propiram fumarate 1
Diclofenac sodium 1
CAM 1
Ceruletide 1
Nephron 1
niacin 1
Estracyt 1
Glycerol 1
Percodan 1
Duloxetine 1
Proglumide 1
Gefitinib 1
Axitinib 1
CPT-11 1
Domperidone 1
Ibandronate 1
OTC 1
Pavinal 1
Carbenoxolone 1
more...
Enzyme
mitogen-activated protein kinase 9
ERK 8
P-glycoprotein 4
protein kinase 4
trypsin 4
protein kinase C 3
acetylcholinesterase 3
superoxide dismutase 3
CYP3A4 3
MAT 3
MAT 3
alanine aminotransferase 2
lysozyme 2
peroxidase 2
SCS 2
MEK 2
luciferase 2
CCS 2
catalase 2
ACS 1
aspartate aminotransferase 1
acid phosphatase 1
UDP-glucuronosyltransferase 1
MTD 1
tryptase 1
prostate-specific antigen 1
gamma-glutamyl transpeptidase 1
MSAS 1
collagenase 1
tyrosine hydroxylase 1
GRK5 1
furin 1
SOR 1
MDP 1
lactate dehydrogenase 1
NO synthase 1
DAT 1
CaMKII 1
legumain 1
phosphoribulokinase 1
alkaline phosphatase 1
MCS 1
AST 1
adenylate cyclase 1
SOR 1
APC 1
FADS 1
NCP 1
NADPH oxidase 1
GTP cyclohydrolase I 1
elastase 1
NADPH oxidase 1
kinesin 1
ornithine transcarbamylase 1
IKK 1
ATPase 1
Compound
Dec 242
Clin 219
Morphine 116
Methadone 39
APAP 31
sulfate 29
Oxycodone 25
phenol 21
Buprenorphine 19
Ketamine 17
Tramadol 16
calcium 16
water 14
ATP 14
TTS 14
NMDA 12
TNF 12
sodium 12
oxygen 12
Optimal 12
His 9
Pac 9
noradrenaline 9
glutamate 8
methionine 7
Codeine 7
Naloxone 7
PRN 7
ethanol 6
glycerol 6
Hydromorphone 6
glucose 5
creatinine 5
phosphate 5
nitric oxide 5
formaldehyde 5
DSM 4
hydrogen 4
TCM 4
Ketorolac 4
MTT 4
ASA 4
Lidocaine 4
Tetrahydrocannabinol 4
Adrenal 4
strontium 4
TCM 4
acetate 4
Pentazocine 3
ANS 3
serine 3
PID 3
ATC 3
ATF 3
Parenteral 3
MDA 3
Pentazocine 3
isopropanol 3
DNA 3
propionic acid 3
5-HT 3
GABA 3
ATC 3
ANS 3
GABA 3
PEG 3
Dexmedetomidine 3
proline 3
propionic acid 3
aspartic acid 3
PID 3
Naltrexone 3
lysine 3
Sufentanil 2
anthracene 2
ETA 2
Prochlorperazine 2
Alfentanil 2
PPI 2
acetonitrile 2
more...