Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0596240 (
cancer pain
)
3,066
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
189
opioid receptor
77
Mol
31
Walker
24
cage
22
cytokine
16
She
15
OPRM1
14
CSF
14
calcitonin
13
endothelin-1
13
ATP
13
nerve growth factor
13
NMDA receptor
13
TNF
12
CB2
12
CB1
11
beta-endorphin
11
TRPV1
11
substance P
10
glial fibrillary acidic protein
10
osteosarcoma
10
reserved
9
cannabinoid receptor
9
dynorphin
8
P2X
8
COMT
8
CYP2D6
8
calcium channel
8
ABCB1
8
cyclooxygenase-2
8
TLR4
8
BPI
7
mu opioid receptor
7
short form
7
PRN
7
THC
7
COX-2
7
delta opioid receptor
7
IL-6
7
more...
Disease
cancer
1631
chronic pain
437
tumor
244
addiction
168
depression
167
metastases
94
bone cancer
83
breast cancer
53
carcinoma
48
bone metastases
42
tumor growth
40
lung cancer
34
osteoarthritis
30
pruritus
28
psychological distress
28
pancreatic cancer
26
celiac disease
26
melanoma
25
cognitive impairment
24
migraine
24
rheumatoid arthritis
23
prostate cancer
22
arthritis
22
postherpetic neuralgia
22
refractory cancer
21
Frey
21
delirium
21
confusion
20
physical dependence
19
substance abuse
19
multiple sclerosis
19
xerostomia
19
squamous cell carcinoma
18
peripheral neuropathy
18
hallucinations
18
fibromyalgia
18
tumor progression
18
fibrosarcoma
18
drug addiction
17
drug abuse
16
more...
Symptom
cancer pain
3066
pain
2630
analgesia
461
constipation
155
nausea
142
breakthrough pain
131
acute pain
92
headache
91
vomiting
88
bone pain
68
sleepiness
62
anesthesia
57
nausea and vomiting
50
fatigue
43
low back pain
36
Neuropathic pain
30
dizziness
29
back pain
26
anorexia
24
abdominal pain
24
dyspnea
22
spasticity
19
myoclonus
17
discomfort
16
cachexia
15
discomfort
15
insomnia
15
erythema
12
diarrhea
12
neuralgia
11
arthralgia
10
facial pain
9
weakness
9
chest pain
8
seizures
7
orofacial pain
7
distraction
7
stigma
7
agitation
7
chronic back pain
6
more...
Drug
Fentanyl
57
CSF
16
Monit
10
Clonidine
8
Codeine
7
Gabapentin
7
9-THC
7
Codeine
7
Morphine sulfate
5
Tramal
4
Ketorolac
4
Tapentadol
4
Check
3
Nabilone
3
Meconium
3
Ziconotide
3
Tramadol hydrochloride
3
Meth
3
Cardiovasc
3
Donepezil
3
p75
2
caffeine
2
Bupivacaine
2
lysine
2
G-CSF
2
ETA
2
Indomethacin
2
Oxycon
2
Subutex
2
Pregabalin
2
Bayer
2
BH4
2
Ketorolac tromethamine
2
ENT
2
Oxycontin
2
Opium
2
SrCl2
2
CCL
1
Propiram fumarate
1
EE2
1
more...
Enzyme
mitogen-activated protein kinase
9
ERK
8
P-glycoprotein
4
trypsin
4
protein kinase
4
acetylcholinesterase
3
MAT
3
CYP3A4
3
superoxide dismutase
3
protein kinase C
3
MAT
3
peroxidase
2
lysozyme
2
alanine aminotransferase
2
luciferase
2
SCS
2
CCS
2
catalase
2
MEK
2
ACS
1
aspartate aminotransferase
1
acid phosphatase
1
UDP-glucuronosyltransferase
1
MTD
1
tryptase
1
prostate-specific antigen
1
CaMKII
1
MDP
1
legumain
1
MSAS
1
lactate dehydrogenase
1
tyrosine hydroxylase
1
GRK5
1
furin
1
adenylate cyclase
1
alkaline phosphatase
1
APC
1
FADS
1
NADPH oxidase
1
kinesin
1
more...
Compound
Dec
242
Clin
219
Morphine
116
Methadone
39
APAP
31
sulfate
29
Oxycodone
25
phenol
21
Buprenorphine
19
Ketamine
17
Tramadol
16
calcium
16
water
14
ATP
14
TTS
14
Optimal
12
TNF
12
oxygen
12
NMDA
12
sodium
12
His
9
Pac
9
noradrenaline
9
glutamate
8
methionine
7
Codeine
7
PRN
7
Naloxone
7
ethanol
6
glycerol
6
Hydromorphone
6
formaldehyde
5
glucose
5
creatinine
5
phosphate
5
nitric oxide
5
TCM
4
acetate
4
TCM
4
MTT
4
more...