Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0595921 (intraocular pressure)
 11,750 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
LRRC27 11.4
SERPINE3 11.4
mutant myocilin 10.5
C6orf176 10.4
TGM2 protein 10.4
CSPG6 10.4
prostanoid FP receptor 10.3
Bardet-Biedl syndrome 5 9.8
Optimedin 9.8
formin homology 2 domain containing 1 9.8
optimedin 9.8
MYOC 9.7
myoc 9.5
SRBD1 9.4
70kD) 9.4
ZNF677 9.4
Myocilin 9.3
type IV collagen alpha 1 9.2
olfactomedin-like 9.2
myocilin 9.1
TMEM136 9.1
latent transforming growth factor beta binding protein 2 9.1
GLC3A 9.1
SH3PXD2B 9.1
TMCO1 9.1
XFS 8.9
Lysyl oxidase-like 1 8.8
myomesin 1 8.8
FP prostanoid receptor 8.8
DGKG 8.8
AIBP 8.8
GLCCI1 8.7
WDR36 8.7
WD repeat domain 36 8.6
PLEKHG3 8.6
ANGPTL7 8.6
actin related protein 2/3 complex 8.6
GAS7 8.5
TC-2 8.4
GCAP3 8.4
PPCD1 8.4
ARHGEF12 8.2
apolipoprotein A-I binding protein 8.2
TMTC2 8.2
Novel transcript 8.2
TULP2 8.2
calgranulin C 8.1
MVB12B 8.1
CPAMD8 7.9
EP3A 7.9
pyrin domain containing 1 7.9
Raftlin 7.8
TZN 7.8
RBPMS 7.7
trp7 7.7
glutathione S-transferase M3 7.7
ACZ 7.7
ICA1 7.6
MYOF 7.6
CRYGS 7.6
ALC2 7.6
RAB8 7.6
GPR158 7.6
STK16 7.6
MS4A3 7.6
FNDC3B 7.6
CACNA2D1 7.5
LOXL1 7.5
CAV2 7.4
DRAM2 7.4
COL16A1 7.4
SIX6 7.4
excitatory amino-acid carrier 1 7.3
CA IV 7.3
Aquaporin-9 7.3
SLC44A1 7.2
RNA-binding protein with multiple splicing 7.2
Noelin 7.2
DYNLL2 7.2
forkhead box C1 7.2
more...
Disease
intraocular pressure 11.4
Aphakic glaucoma 11.4
Corneal exfoliation 11.4
Retinal incarceration 11.4
Drug-induced glaucoma 11.4
Scleral pigmentation 11.4
Ciliary block glaucoma 11.4
Optic nerve cupping 11.4
Brown cataract 11.4
Total hyphaema 11.4
Unilateral cataract 11.4
Simple microphthalmos 11.4
Zoster Sine Herpete 11.4
Phacolytic glaucoma 11.1
Corticosteroid-induced glaucoma 11.0
IOP decreased 11.0
Aqueous misdirection 10.8
acidosis; renal 10.8
Acute glaucoma 10.7
Posner-Schlossman syndrome 10.7
Ghost cell glaucoma 10.7
Plateau iris syndrome 10.6
Malignant glaucoma 10.5
low tension glaucoma 10.5
ocular hypertension 10.4
Uveitic glaucoma 10.4
Glaucomatous optic atrophy 10.4
Chronic open angle glaucoma 10.4
Synchysis scintillans 10.4
Primary open-angle glaucoma 10.3
Secondary glaucoma 10.1
Corneal decompensation 10.1
open angle glaucoma 10.0
Retinal ischemia 10.0
angle recession 9.9
Phacomorphic glaucoma 9.8
Primary congenital glaucoma 9.8
Krukenberg spindle 9.8
Noninfectious anterior uveitis 9.8
Pupil block glaucoma 9.8
Serous choroidal detachment 9.8
Other glaucoma 9.8
Primary angle-closure glaucoma 9.8
conjunctival degeneration 9.8
Pupillary block 9.8
closed angle glaucoma 9.7
Acute angle-closure glaucoma 9.7
Peripheral anterior synechiae 9.6
childhood glaucoma 9.6
neovascular glaucoma 9.5
GLC1A 9.4
glaucoma 9.4
XFS 9.4
aqueous humor 9.4
GLC1F 9.4
aqueous outflow obstruction 9.4
GLC1B 9.4
Choroidal effusion 9.4
Glaucoma and ocular hypertension 9.4
Francois syndrome 9.4
plateau iris 9.4
Pigment dispersion syndrome 9.3
UGH syndrome 9.2
TLPD 9.2
goniodysgenesis 9.2
Primary empty sella syndrome 9.1
Corneal allograft rejection 9.1
Viral retinitis 9.1
Orbital emphysema 9.0
Severe visual impairment 8.9
rubeosis iridis 8.9
Axenfeld's anomaly 8.8
Uveal effusion syndrome 8.8
GLC3B 8.8
parotitis epidemica 8.8
Axial myopia 8.8
Posterior keratoconus 8.8
GLC3 8.8
iridodialysis 8.7
Chandler's syndrome 8.6
more...
Symptom
Corneal blood staining 11.0
Upper lid retraction 10.8
iridodonesis 8.8
circulatory problem 8.6
Scintillating scotoma 8.6
Eyelid retraction 8.2
eye pain 7.7
bloodshot eyes 7.1
Stinging 6.6
blurred vision 6.6
Postoperative vomiting 6.5
Flare 6.5
abnormal taste 6.5
Bell's phenomenon 6.4
Orthostasis 6.3
Visual disturbances 6.2
photophobia 6.0
photopsia 5.9
Blanching 5.7
dry eye 5.6
periorbital edema 5.4
blepharospasm 5.4
eye discharge 5.3
Kayser-Fleischer ring 5.2
metamorphopsia 5.1
Overlying 5.0
thinning 4.7
No pain 4.6
pallor 4.6
aniseikonia 4.3
Burning 4.2
hypalgesia 4.0
dysesthesia 3.8
Cushingoid 3.7
Cushingoid 3.6
hypertonia 3.4
ophthalmoplegia 3.4
Postoperative nausea and vomiting 3.3
hypotonia 3.3
breath holding 3.3
Fluctuation 3.2
anesthesia 3.1
Physical findings 3.0
Sedation 3.0
discomfort 3.0
testicular pain 3.0
discomfort 2.9
sneezing 2.8
hypocapnia 2.7
tingling 2.7
syncopal episodes 2.4
Decreased activity 2.3
muscle rigidity 2.3
torticollis 2.3
tense 2.3
Anoxia 2.3
retching 2.3
ketonuria 2.3
nasal congestion 2.3
excessive sweating 2.2
hyperoxia 2.2
hypercapnia 2.2
fasciculation 2.1
headache 2.0
bitter taste 1.9
spasm 1.9
collapse 1.7
neuralgia 1.6
Stiffness 1.5
dry skin 1.4
vomiting 1.4
pain 1.4
tinnitus 1.3
paresis 1.2
decreased appetite 1.2
nausea 1.1
cough 1.1
sore throat 1.0
analgesia 0.9
polyuria 0.8
more...
Drug
Breath-O 11.4
Epinephrine bitartrate 11.4
Demecarium bromide 11.4
Brovincamine fumarate 11.4
Ocupress 11.4
Ocupress 11.4
Pilocarpine nitrate 10.8
Iopidine 10.7
Rescula 10.7
Nitro-bid 10.4
Iopidine 10.4
Pentyde 10.4
Echothiophate iodide 10.4
Latanoprost 10.3
Travoprost 10.3
Loteprednol etabonate 10.3
Tafluprost 10.2
Trusopt 10.2
Betoptic 10.2
Trusopt 10.2
Bimatoprost 10.2
Rimexolone 10.1
Betoptic 10.0
Alphagan 9.9
Alphagan 9.8
Propine 9.8
Lotemax 9.8
Timolol 9.8
Timolol maleate 9.7
Azopt 9.7
Timoptol 9.6
Clobetasone butyrate 9.5
Difluprednate 9.4
Betagan 9.4
Miochol 9.4
Betagan 9.4
Ganda 9.4
Oxymetazoline hydrochloride 9.4
Retisert 9.1
Phospholine Iodide 9.1
Ophthetic 8.9
Ophthetic 8.9
Tubocurarine chloride 8.8
Tobrex 8.6
Anectine 8.4
OP-2 8.3
Dapiprazole 8.2
1-Methylimidazole 8.2
Epinephrine hydrochloride 8.2
Diamox 8.2
C3F8 8.1
Fluocortolone 7.9
Kallidinogenase 7.9
Nepafenac 7.9
Sodium hyaluronate 7.9
Tropicamide 7.8
Sarpogrelate hydrochloride 7.7
Fomivirsen 7.6
Pilocarpine 7.5
Pranoprofen 7.4
Lixivaptan 7.4
Span 40 7.3
Sulfamide 7.3
Dexamethasone acetate 7.3
Bextra 7.2
Bendazac 7.2
FML 7.1
Meditec 7.1
Tobi 7.0
Lergotrile 6.9
Avelox 6.8
Oxybuprocaine 6.8
Span 60 6.6
balanced salt solution 6.6
Indocid 6.6
Nipradilol 6.5
Arfonad 6.5
Cod liver oil 6.5
Dibenzyline 6.3
Ranibizumab 6.3
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Enzyme
carbonic anhydrase 6.7
SOAT 6.4
NAT 5.5
octopine dehydrogenase 5.1
prostaglandin F synthase 5.0
AFR 4.8
3-mercaptopyruvate sulfurtransferase 4.5
nicotinamide mononucleotide adenylyltransferase 4.4
CYP46A1 4.0
3alpha-hydroxysteroid dehydrogenase 3.9
NQO2 3.8
Lod 3.8
carboxypeptidase E 3.8
lysophospholipase D 3.6
SCP 3.6
monoacylglycerol lipase 3.6
Thy1 3.5
hyaluronidase 3.4
phosphoribulokinase 3.4
ADH3 3.4
chymotrypsin 3.3
hyaluronidase 3.1
endothelin-converting enzyme 3.1
arylalkylamine N-acetyltransferase 3.0
mu-calpain 3.0
TdT 2.8
FAST 2.8
prostacyclin synthase 2.8
biotinidase 2.8
m-calpain 2.7
adenylate cyclase 2.7
lysyl oxidase 2.7
TSP-1 2.7
CGT 2.6
myosin light chain kinase 2.6
choline acetyltransferase 2.6
NPL 2.6
prostaglandin synthetase 2.6
N-acetyltransferase 2.5
chondroitinase 2.4
carbonyl reductase 2.4
cystathionine gamma-lyase 2.4
chondroitinase 2.3
glutamine synthetase 2.3
guanylate cyclase 2.3
PI-PLC 2.2
tissue plasminogen activator 2.2
heparinase 2.1
NOS 2.0
neutral sphingomyelinase 2.0
SOR 1.9
glycerol kinase 1.9
apyrase 1.8
CFI 1.8
TMT 1.8
lipoxygenase 1.8
MMP-3 1.7
phenol oxidase 1.7
PAM 1.5
interstitial collagenase 1.5
cystathionine beta-synthase 1.5
NADPH-diaphorase 1.5
IKK 1.5
angiotensin-converting enzyme 2 1.4
nucleotidase 1.4
heme oxygenase 1.4
ECH 1.4
STR 1.4
aldose reductase 1.3
PDK1 1.3
GRK5 1.3
caspase-8 1.3
cholinesterase 1.2
15-lipoxygenase 1.2
phosphodiesterase 1.2
TSA 1.2
NO synthase 1.2
MAP 1.1
tissue kallikrein 1.1
PKG 1.1
more...
Compound
CBS 113A 11.4
Brinzolamide 11.0
Dorzolamide 10.7
Apraclonidine 10.7
Fluorometholone 10.5
Levobunolol 10.5
Levobunolol hydrochloride 10.4
1-ethyl-1,2,3,4-tetrahydroquinoline 10.4
Metipranolol 10.3
Brimonidine 10.1
Dipivefrin 10.1
CI-634 9.8
C7H9NO2 9.8
Timolol 9.8
Enalkiren 9.1
Betaxolol 9.0
PGD3 8.9
Cannabichromene 8.8
Carteolol 8.6
Dichlorphenamide 8.6
beta-Glycyrrhetinic acid 8.6
Dihydrocortisol 8.6
2-methyl-1,2,3,4-tetrahydroquinoline 8.4
isonicotinoyl chloride 8.2
Pilocarpine hydrochloride 8.1
3-pyridinesulfonamide 8.1
Ethoxzolamide 8.1
Aminothiazole 8.1
3-methylbutanamide 8.1
Corynanthine 8.1
Methazolamide 8.1
Fluocinolone acetonide 8.0
Vasocon 7.9
Loganic acid 7.8
Echothiophate 7.7
Chlorcyclizine 7.7
Anectine 7.5
LGE2 7.5
Pilocarpine 7.5
Betnesol 7.4
Pralidoxime chloride 7.4
Felbinac 7.3
Minipress 7.3
Acetazolamide 7.3
1-Nitronaphthalene 7.2
Metocurine 7.2
Adrenal 7.1
Cannabinol 7.0
Allergan 7.0
Dexamethasone acetate 6.9
PGD1 6.8
Pirbuterol 6.6
Diadenosine tetraphosphate 6.6
KI3 6.6
VCC 6.6
Cyclopentolate 6.5
Diphenhydramine 6.5
Prednisolone acetate 6.5
Bremazocine 6.5
Ethacrynic acid 6.4
Complamin 6.4
Succinylcholine 6.3
Bretylium tosylate 6.2
1,2,3,4-tetrahydroquinoline 6.2
1,2,3,4-tetrahydroquinoline 6.2
Cosyntropin 6.2
Dibenzyline 6.2
Retinal 6.2
Ethacrynic acid 6.1
Dormicum 6.1
Lumicolchicine 5.9
PGE3 5.9
Triamcinolone 5.8
MIF-I 5.8
1-methyl-1H-imidazole 5.7
Oxymetazoline 5.7
Aminoadipic acid 5.7
Moxonidine 5.7
Pancuronium 5.7
Tolmetin 5.6
more...