Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0595921 (intraocular pressure)
11,750 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 685
carbonic anhydrase 274
lamp 211
collagen 194
Mol 164
axonal 147
She 82
myocilin 76
vascular endothelial growth factor 75
OCT 68
DBA 65
glial fibrillary acidic protein 61
Rho 55
ATP 47
adenylate cyclase 45
fibronectin 44
beta 1 43
calcium channel 41
AMP 38
nitric oxide synthase 36
endothelin-1 35
strabismus 35
aniridia 34
VEGF 34
CA II 32
cytokine 31
endoplasmic reticulum 31
reserved 31
cyclooxygenase 30
caspase-3 30
ANOVA 29
lacrimal 29
MYOC 29
ERG 29
albumin 28
MRI 28
insulin 28
substance P 26
ATPase 25
CO2 25
brain-derived neurotrophic factor 24
Rho kinase 24
elastin 24
hemoglobin 24
hole 24
CA1 23
TNF 22
THC 22
superoxide dismutase 20
inducible nitric oxide synthase 20
angiotensin II 19
tumor necrosis factor 19
Myocilin 19
carbonic anhydrase II 19
PGD2 19
tissue plasminogen activator 18
CYP1B1 18
hyaluronidase 18
RhoA 18
EP2 17
membrane-bound 17
Bcl-2 17
Endothelin-1 16
peroxidase 16
PBS 16
CB1 16
GTPase 16
phosphodiesterase 16
ASA 16
matrix metalloproteinase 15
glycoprotein 15
HLA 15
NTG 15
XFS 15
GABA 15
CA IV 14
optineurin 14
mutant myocilin 14
renin 14
Carbonic anhydrase 14
more...
Disease
intraocular pressure 11750
glaucoma 5908
cataract 1220
aqueous humor 1007
ocular hypertension 865
blindness 652
cornea 637
open angle glaucoma 531
neuropathy 483
ischemia 308
myopia 281
retinal detachment 269
sclera 257
hypertension 242
uveitis 234
diabetes 190
Primary open-angle glaucoma 172
neovascular glaucoma 169
conjunctiva 168
corneal edema 134
diabetic retinopathy 127
macular edema 123
retinopathy 116
proptosis 116
endophthalmitis 108
macular degeneration 91
IOP decreased 90
eye disease 90
astigmatism 86
anterior uveitis 85
scotoma 84
Anterior 81
tumor 81
refractive error 78
keratopathy 76
cystoid macular edema 75
strabismus 68
IOL 66
SEM 65
DBA 65
keratitis 64
depression 63
keratoconus 58
pulmonary tuberculosis 57
Retinal ischemia 57
proliferative diabetic retinopathy 52
uvea 52
Best 48
low tension glaucoma 48
prolapse 48
XFS 47
Retina 47
Retina 47
ischemic optic neuropathy 44
iritis 44
cancer 44
melanoma 41
amblyopia 40
closed angle glaucoma 40
rubeosis iridis 40
migraine 38
diplopia 38
Alzheimer's disease 37
Optic nerve 37
systemic disease 36
iridocyclitis 36
optic atrophy 36
synechia 35
conjunctivitis 34
childhood glaucoma 33
proliferative vitreoretinopathy 33
Posterior 32
Cornea 31
cytomegalovirus 31
Graves' disease 31
Cornea 31
sympathomimetic 30
SWS 29
Graves' ophthalmopathy 28
obesity 28
more...
Symptom
anesthesia 341
pain 252
thinning 110
headache 81
blurred vision 74
discomfort 68
discomfort 67
dry eye 46
photophobia 38
collapse 34
vomiting 31
eye pain 30
pallor 23
hypotonia 21
weakness 21
analgesia 19
cough 19
fatigue 19
nausea 19
blepharospasm 16
hypercapnia 13
ophthalmoplegia 13
hypothermia 10
spasm 10
seizures 10
hyperoxia 9
sleepiness 7
erythema 7
tinnitus 6
angina 6
Flare 6
sneezing 5
agitation 5
dysesthesia 5
paresis 5
respiratory distress 5
tremor 5
hypertonia 5
hypocapnia 4
nausea and vomiting 4
exhaustion 4
tense 4
anorexia 4
periorbital edema 4
dyspnea 4
Sedation 4
functional recovery 4
iridodonesis 4
myalgia 3
photopsia 3
metamorphopsia 3
tingling 3
overweight 3
Ill 3
torticollis 3
Visual disturbances 3
acute stress 3
Corneal blood staining 3
dystonia 3
diarrhea 3
vertigo 3
Bell's phenomenon 2
acute pain 2
ENT 2
breath holding 2
abdominal pain 2
Burning 2
starvation 2
Blanching 2
neuralgia 2
constipation 2
cyanosis 2
numbness 2
flushing 2
fasciculation 2
polyuria 2
bitter taste 2
Eyelid retraction 2
sore throat 2
Fluctuation 2
more...
Drug
Timolol 137
Latanoprost 75
balanced salt solution 56
Pilocarpine 44
Bimatoprost 39
Timolol maleate 27
ascorbate 24
Diphenhydramine 23
Fluorescein 22
Timoptol 22
nitroglycerin 22
Diurnal 22
Travoprost 20
Indomethacin 20
9-THC 19
Fluorescein 19
Forskolin 19
Bevacizumab 19
Clonidine 18
Diamox 17
SF6 15
Sodium hyaluronate 14
C3F8 14
Betoptic 13
Dermatol 12
Alphagan 12
Trusopt 12
Loteprednol etabonate 11
Monit 11
Cardiovasc 11
Nephron 11
ICI 10
ETA 10
vitamin E 10
Alphagan 10
Betoptic 10
Trusopt 10
CSF 9
Gel 9
Rescula 9
caffeine 9
Tafluprost 8
Ringer's solution 7
Meditec 7
MAP 6
lysine 6
Ranibizumab 6
Propofol 6
Span 60 6
FLP 5
niacin 5
Tropicamide 5
Iopidine 5
Atenolol 5
Dial 5
ABC 5
Voltaren 5
Leaf 5
p75 4
Asthma 4
Salbutamol 4
Iloprost 4
Nadolol 4
Propine 4
DPE 4
Ganda 4
Fenoldopam 4
Prednisolone 3
Viagra 3
Viagra 3
Clobetasone butyrate 3
Diclofenac sodium 3
CAM 3
Methylcellulose 3
Fentanyl 3
Mitomycin-C 3
Nitric Oxide 3
Azopt 3
Atropine 3
Phentolamine 3
more...
Enzyme
carbonic anhydrase 279
adenylate cyclase 47
chymotrypsin 41
mitogen-activated protein kinase 34
ERK 33
protein kinase 32
ATPase 26
protein kinase C 26
superoxide dismutase 21
peroxidase 21
hyaluronidase 20
caspase-3 20
tissue plasminogen activator 19
hyaluronidase 18
acetylcholinesterase 17
phosphodiesterase 16
guanylate cyclase 15
renin 14
choline acetyltransferase 14
catalase 13
NO synthase 13
ACS 13
NAT 11
lipoxygenase 11
lactate dehydrogenase 11
NOS 11
cholinesterase 11
luciferase 11
phospholipase C 10
focal adhesion kinase 10
alanine aminotransferase 10
glutamine synthetase 9
ACE 9
phospholipase A2 8
thrombin 8
monoamine oxidase 8
PARP 7
MAP 6
calcineurin 6
myosin light chain kinase 6
caspase-8 6
alkaline phosphatase 5
TdT 5
glutathione peroxidase 5
N-acetyltransferase 5
IKK 5
Thy1 5
collagenase 5
prostaglandin synthetase 4
MMP-3 4
GSK 4
heme oxygenase 4
chondroitinase 4
chondroitinase 4
NADPH-diaphorase 4
kallikrein 4
RNase 3
glutathione S-transferase 3
MIP 3
plasmin 3
reverse transcriptase 3
aldose reductase 3
RNase 3
monoacylglycerol lipase 3
cytochrome oxidase 3
tyrosine hydroxylase 3
trypsin 3
STR 3
succinate dehydrogenase 3
diaphorase 3
lysyl oxidase 3
MMP 3
caspase-1 3
arylalkylamine N-acetyltransferase 2
TSP-1 2
NQO1 2
PDE 2
lipoprotein lipase 2
apyrase 2
diaphorase 2
more...
Compound
Dec 712
Clin 516
Adrenal 421
water 251
sodium 231
oxygen 181
Retinal 158
Timolol 136
calcium 123
nitric oxide 109
glutamate 99
glucose 81
DNA 80
phosphate 77
DBA 65
cAMP 65
DBA 65
DBA 65
His 59
PGE2 55
acetate 54
Acetazolamide 50
sulfate 49
ATP 47
CO2 43
Brimonidine 41
AMP 40
Pilocarpine 40
salt 39
hyaluronic acid 39
hydrogen 38
Melatonin 32
cGMP 32
arginine 32
noradrenaline 30
Prostaglandin 29
prostaglandin F2alpha 29
Prostaglandin 29
ASA 29
potassium 29
Dorzolamide 28
HCl 28
zinc 26
Dexamethasone 26
aluminum 25
glycerol 24
MMC 23
Allergan 23
Diphenhydramine 23
Pac 23
Cardiol 23
nitrogen 22
TNF 22
Betaxolol 22
Apraclonidine 22
PEG 22
dUTP 21
prostaglandin E1 20
5-FU 20
Indomethacin 20
ethanol 19
leucine 19
PGD2 19
Forskolin 19
tyrosine 19
silicon 18
Collagen 17
Metipranolol 17
PEG 17
Brinzolamide 17
Isoproterenol 16
5-HT 16
iodine 16
silver 16
NMDA 16
6-12 15
Adenosine 15
iron 15
Propranolol 15
GABA 15
more...