Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0595921 (intraocular pressure)
 11,750 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 685
carbonic anhydrase 274
lamp 211
collagen 194
Mol 164
axonal 147
She 82
myocilin 76
vascular endothelial growth factor 75
OCT 68
DBA 65
glial fibrillary acidic protein 61
Rho 55
ATP 47
adenylate cyclase 45
fibronectin 44
beta 1 43
calcium channel 41
AMP 38
nitric oxide synthase 36
strabismus 35
endothelin-1 35
VEGF 34
aniridia 34
CA II 32
cytokine 31
endoplasmic reticulum 31
reserved 31
caspase-3 30
cyclooxygenase 30
MYOC 29
lacrimal 29
ANOVA 29
ERG 29
albumin 28
MRI 28
insulin 28
substance P 26
CO2 25
ATPase 25
hemoglobin 24
Rho kinase 24
brain-derived neurotrophic factor 24
hole 24
elastin 24
CA1 23
TNF 22
THC 22
superoxide dismutase 20
inducible nitric oxide synthase 20
angiotensin II 19
PGD2 19
carbonic anhydrase II 19
Myocilin 19
tumor necrosis factor 19
hyaluronidase 18
RhoA 18
tissue plasminogen activator 18
CYP1B1 18
membrane-bound 17
EP2 17
Bcl-2 17
GTPase 16
Endothelin-1 16
CB1 16
ASA 16
peroxidase 16
phosphodiesterase 16
PBS 16
matrix metalloproteinase 15
XFS 15
HLA 15
glycoprotein 15
NTG 15
GABA 15
optineurin 14
calcitonin 14
CA IV 14
renin 14
Carbonic anhydrase 14
mutant myocilin 14
neurotrophin 14
choline acetyltransferase 14
ACS 13
Pol 13
TLR4 13
adenylyl cyclase 13
connective tissue growth factor 13
Rec 13
vascular endothelium 13
adenosine receptor 13
Thy-1 13
NMDA receptor 13
PGF 13
IL-6 13
P2X 12
Gen 12
RPE 12
LC3 12
myosin 12
SMA 12
asymmetrical 12
EP3 12
ET-1 12
vasopressin 12
natriuretic peptide 12
atrial natriuretic peptide 12
PLA 12
catalase 12
guanylate cyclase 12
vimentin 12
MAPK 12
p38 12
crystallin 12
PEG 12
calgranulin C 12
polypeptide 11
serum albumin 11
lipoxygenase 11
lipopolysaccharide 11
p53 11
bradykinin 11
GSH 11
NAT 11
calretinin 11
ETA 10
chronic renal failure 10
lactate dehydrogenase 10
myosin light chain 10
opioid receptor 10
smooth muscle actin 10
AQP4 10
EP4 10
cannabinoid receptor 9
EP1 9
calpain 9
retinal protein 9
glutamine synthetase 9
neurotrophic factor 9
thrombin 9
cyclooxygenase-2 9
AQP1 9
atrial natriuretic factor 9
synaptophysin 9
phosphatase 8
fused 8
muscarinic receptor 8
CSF 8
CB2 8
glucocorticoid receptor 8
SOD 8
PCL 8
JNK 8
NMR 8
CCT 8
ADP 8
acetylcholinesterase 8
SCH 8
neurofibromatosis 7
MMP-2 7
more...
Disease
intraocular pressure 11750
glaucoma 5908
cataract 1220
aqueous humor 1007
ocular hypertension 865
blindness 652
cornea 637
open angle glaucoma 531
neuropathy 483
ischemia 308
myopia 281
retinal detachment 269
sclera 257
hypertension 242
uveitis 234
diabetes 190
Primary open-angle glaucoma 172
neovascular glaucoma 169
conjunctiva 168
corneal edema 134
diabetic retinopathy 127
macular edema 123
retinopathy 116
proptosis 116
endophthalmitis 108
macular degeneration 91
IOP decreased 90
eye disease 90
astigmatism 86
anterior uveitis 85
scotoma 84
Anterior 81
tumor 81
refractive error 78
keratopathy 76
cystoid macular edema 75
strabismus 68
IOL 66
SEM 65
DBA 65
keratitis 64
depression 63
keratoconus 58
Retinal ischemia 57
pulmonary tuberculosis 57
proliferative diabetic retinopathy 52
uvea 52
Best 48
prolapse 48
low tension glaucoma 48
Retina 47
XFS 47
Retina 47
iritis 44
cancer 44
ischemic optic neuropathy 44
melanoma 41
amblyopia 40
rubeosis iridis 40
closed angle glaucoma 40
diplopia 38
migraine 38
Alzheimer's disease 37
Optic nerve 37
systemic disease 36
optic atrophy 36
iridocyclitis 36
synechia 35
conjunctivitis 34
childhood glaucoma 33
proliferative vitreoretinopathy 33
Posterior 32
Cornea 31
cytomegalovirus 31
Cornea 31
Graves' disease 31
sympathomimetic 30
SWS 29
obesity 28
Graves' ophthalmopathy 28
cardiovascular disease 27
asthma 26
herpes simplex 26
stroke 26
Posner-Schlossman syndrome 24
Secondary glaucoma 24
Brown 23
hypopyon 23
metastases 23
pruritus 22
retinoblastoma 21
retinopathy of prematurity 21
THC 21
vitreous humor 21
cold 21
hyperopia 20
retinitis pigmentosa 19
lens opacity 19
angle recession 18
nystagmus 18
chorioretinal atrophy 18
Primary congenital glaucoma 18
emphysema 18
vascular disease 18
macular hole 17
allergic conjunctivitis 17
NAME 16
mole 16
Age-related macular degeneration 15
visual dysfunction 15
chronic disease 15
scleritis 15
RGS 15
megalocornea 14
renal disease 14
uveal melanoma 13
corneal ulcer 13
chronic renal failure 13
CMV retinitis 13
Syndrome 13
atherosclerosis 12
mole 12
hypertensive retinopathy 12
keratoconjunctivitis 12
pertussis 12
goniodysgenesis 12
Acute angle-closure glaucoma 12
leprosy 11
Marfan syndrome 11
plaque 11
epiphora 11
hemangioma 11
GSH 11
Parkinson's disease 11
cycloplegia 11
Evans 11
type 2 diabetes 11
DM1 11
sarcoidosis 10
blepharitis 10
amaurosis 10
West 10
xanthogranuloma 10
Fuchs' endothelial dystrophy 10
Scheie 10
Cannabis 10
degenerative disease 10
plateau iris 10
Leber's hereditary optic neuropathy 10
optic neuritis 10
cholera 10
confusion 10
anisometropia 10
fits 10
staphyloma 10
hydrocephalus 10
multiple sclerosis 9
Malignant glaucoma 9
AIDS 9
hyperthyroidism 9
more...
Symptom
anesthesia 341
pain 252
thinning 110
headache 81
blurred vision 74
discomfort 68
discomfort 67
dry eye 46
photophobia 38
collapse 34
vomiting 31
eye pain 30
pallor 23
hypotonia 21
weakness 21
analgesia 19
nausea 19
cough 19
fatigue 19
blepharospasm 16
hypercapnia 13
ophthalmoplegia 13
seizures 10
spasm 10
hypothermia 10
hyperoxia 9
sleepiness 7
erythema 7
tinnitus 6
Flare 6
angina 6
agitation 5
sneezing 5
dysesthesia 5
tremor 5
paresis 5
respiratory distress 5
hypertonia 5
hypocapnia 4
nausea and vomiting 4
exhaustion 4
tense 4
anorexia 4
iridodonesis 4
periorbital edema 4
functional recovery 4
Sedation 4
dyspnea 4
photopsia 3
Corneal blood staining 3
dystonia 3
acute stress 3
Ill 3
Visual disturbances 3
torticollis 3
diarrhea 3
metamorphopsia 3
tingling 3
myalgia 3
overweight 3
vertigo 3
lethargy 2
acute pain 2
ENT 2
abdominal pain 2
Burning 2
starvation 2
Blanching 2
neuralgia 2
constipation 2
cyanosis 2
dizziness 2
numbness 2
polyuria 2
bitter taste 2
Fluctuation 2
fasciculation 2
Eyelid retraction 2
sore throat 2
flushing 2
nasal congestion 2
ataxia 2
breath holding 2
Upper lid retraction 2
distraction 2
Bell's phenomenon 2
muscle rigidity 2
Stinging 2
Cushingoid 1
colic 1
neck pain 1
hypalgesia 1
snoring 1
Scintillating scotoma 1
Decreased activity 1
abnormal taste 1
aniseikonia 1
syncope 1
Orthostasis 1
Stiffness 1
Cushingoid 1
dysarthria 1
testicular pain 1
paresthesia 1
Anoxia 1
hopelessness 1
Kayser-Fleischer ring 1
Overlying 1
Physical findings 1
eye discharge 1
enuresis 1
tachypnea 1
retching 1
ketonuria 1
fever of unknown origin 1
Postoperative vomiting 1
acidity 1
excessive sweating 1
sciatica 1
insomnia 1
twitching 1
regurgitation 1
Postoperative nausea and vomiting 1
cancer pain 1
No pain 1
syncopal episodes 1
decreased appetite 1
circulatory problem 1
bloodshot eyes 1
dry skin 1
Drug
Timolol 137
Latanoprost 75
balanced salt solution 56
Pilocarpine 44
Bimatoprost 39
Timolol maleate 27
ascorbate 24
Diphenhydramine 23
nitroglycerin 22
Fluorescein 22
Diurnal 22
Timoptol 22
Travoprost 20
Indomethacin 20
Bevacizumab 19
Fluorescein 19
9-THC 19
Forskolin 19
Clonidine 18
Diamox 17
SF6 15
Sodium hyaluronate 14
C3F8 14
Betoptic 13
Dermatol 12
Trusopt 12
Alphagan 12
Loteprednol etabonate 11
Nephron 11
Cardiovasc 11
Monit 11
Trusopt 10
Alphagan 10
Betoptic 10
vitamin E 10
ETA 10
ICI 10
Rescula 9
Gel 9
CSF 9
caffeine 9
Tafluprost 8
Meditec 7
Ringer's solution 7
Ranibizumab 6
Propofol 6
lysine 6
Span 60 6
MAP 6
Iopidine 5
FLP 5
Voltaren 5
Atenolol 5
Dial 5
Tropicamide 5
Leaf 5
niacin 5
ABC 5
Salbutamol 4
Iloprost 4
Asthma 4
DPE 4
Nadolol 4
p75 4
Ganda 4
Propine 4
Fenoldopam 4
Viagra 3
CAM 3
Diclofenac sodium 3
Clobetasone butyrate 3
Span 40 3
CTX 3
Azopt 3
Methylcellulose 3
ROS 3
Medetomidine 3
Atropine sulfate 3
Prednisolone 3
Lotemax 3
NADH 3
TAK 3
Fentanyl 3
Mitomycin-C 3
Vicryl 3
Tacrolimus 3
Atropine 3
Angiotensin II 3
Nitric Oxide 3
Guanethidine 3
Phentolamine 3
Indocid 3
Viagra 3
Verteporfin 3
Orion 2
Histamine 2
Dapiprazole 2
Retisert 2
Asn 2
Catapres 2
Nipradilol 2
Dexon 2
Vitamin A 2
Inderal 2
Albumin 2
pyridoxal phosphate 2
CTX 2
Cimetidine 2
Ophthetic 2
FML 2
Pilocarpine nitrate 2
Dalteparin 2
Domperidone 2
CTX 2
Echothiophate iodide 2
Sulpiride 2
DM1 2
Moxifloxacin 2
Ophthetic 2
Betagan 2
TMS 2
Ouabain 2
Miochol 2
OP-2 2
Hydergine 2
Nepafenac 2
Ganciclovir 2
Dihydro 2
Donepezil 2
Dakar 2
Sulprostone 2
Dormicum 2
ENT 2
Iopidine 2
DEX 2
Captopril 2
Cimetidine 2
Cidofovir 2
Posture 2
Rimexolone 2
Betagan 2
Sesame oil 1
Difluprednate 1
Rolipram 1
Gabapentin 1
Arfonad 1
Methylene blue 1
Valdecoxib 1
CET 1
Vitamin E 1
Imatinib 1
LCM 1
Phospholine Iodide 1
Simvastatin 1
Kallidinogenase 1
Ethanol 1
Epigallocatechin 1
Polycarbophil 1
LCM 1
Mezlocillin 1
more...
Enzyme
carbonic anhydrase 279
adenylate cyclase 47
chymotrypsin 41
mitogen-activated protein kinase 34
ERK 33
protein kinase 32
ATPase 26
protein kinase C 26
superoxide dismutase 21
peroxidase 21
hyaluronidase 20
caspase-3 20
tissue plasminogen activator 19
hyaluronidase 18
acetylcholinesterase 17
phosphodiesterase 16
guanylate cyclase 15
choline acetyltransferase 14
renin 14
NO synthase 13
ACS 13
catalase 13
lactate dehydrogenase 11
cholinesterase 11
NAT 11
lipoxygenase 11
luciferase 11
NOS 11
focal adhesion kinase 10
phospholipase C 10
alanine aminotransferase 10
ACE 9
glutamine synthetase 9
monoamine oxidase 8
thrombin 8
phospholipase A2 8
PARP 7
myosin light chain kinase 6
caspase-8 6
calcineurin 6
MAP 6
alkaline phosphatase 5
IKK 5
glutathione peroxidase 5
collagenase 5
N-acetyltransferase 5
TdT 5
Thy1 5
NADPH-diaphorase 4
heme oxygenase 4
MMP-3 4
GSK 4
kallikrein 4
prostaglandin synthetase 4
chondroitinase 4
chondroitinase 4
glutathione S-transferase 3
lysyl oxidase 3
RNase 3
MMP 3
succinate dehydrogenase 3
tyrosine hydroxylase 3
trypsin 3
aldose reductase 3
RNase 3
plasmin 3
reverse transcriptase 3
diaphorase 3
cytochrome oxidase 3
monoacylglycerol lipase 3
STR 3
MIP 3
caspase-1 3
arylalkylamine N-acetyltransferase 2
phosphoribulokinase 2
apyrase 2
phosphatidylinositol 3-kinase 2
3-mercaptopyruvate sulfurtransferase 2
PDE 2
complex I 2
transglutaminase 2
lysozyme 2
diaphorase 2
NQO1 2
PDK1 2
carboxypeptidase E 2
FAST 2
enolase 2
MEK 2
protein phosphatase 2A 2
mu-calpain 2
acid phosphatase 2
proteinase K 2
caspase-9 2
creatine kinase 2
PAM 2
heparinase 2
m-calpain 2
urokinase-type plasminogen activator 2
NADPH oxidase 2
endothelin-converting enzyme 2
SCP 2
PKG 2
lipoprotein lipase 2
TSP-1 2
NADPH oxidase 2
BMT 1
pyruvate dehydrogenase 1
glycerol-3-phosphate dehydrogenase 1
ribonuclease 1
CGT 1
lysophospholipase D 1
glutamate decarboxylase 1
CaMKII 1
ornithine decarboxylase 1
nucleotidase 1
tyrosinase 1
nicotinamide mononucleotide adenylyltransferase 1
Lod 1
NQO2 1
ribonuclease 1
diamine oxidase 1
glutathione reductase 1
pyruvate dehydrogenase 1
beta-lactamase 1
MEKK1 1
octopine dehydrogenase 1
prostacyclin synthase 1
PCP 1
PCE 1
ADH 1
matrix metalloproteinase 2 1
GRK5 1
phosphoinositide 3-kinase 1
proteasome 1
tissue kallikrein 1
AMP-activated protein kinase 1
elastase 1
gamma-glutamyl transpeptidase 1
CPT 1
SOR 1
neuraminidase 1
carbonyl reductase 1
TSA 1
chymase 1
CPT 1
transketolase 1
angiotensin-converting enzyme 2 1
beta-galactosidase 1
prostaglandin F synthase 1
glycerol-3-phosphate dehydrogenase 1
TMT 1
glyceraldehyde-3-phosphate dehydrogenase 1
ECH 1
biotinidase 1
cystathionine beta-synthase 1
cystathionine gamma-lyase 1
deaminase 1
APC 1
3alpha-hydroxysteroid dehydrogenase 1
more...
Compound
Dec 712
Clin 516
Adrenal 421
water 251
sodium 231
oxygen 181
Retinal 158
Timolol 136
calcium 123
nitric oxide 109
glutamate 99
glucose 81
DNA 80
phosphate 77
DBA 65
DBA 65
DBA 65
cAMP 65
His 59
PGE2 55
acetate 54
Acetazolamide 50
sulfate 49
ATP 47
CO2 43
Brimonidine 41
AMP 40
Pilocarpine 40
hyaluronic acid 39
salt 39
hydrogen 38
arginine 32
cGMP 32
Melatonin 32
noradrenaline 30
Prostaglandin 29
potassium 29
Prostaglandin 29
prostaglandin F2alpha 29
ASA 29
Dorzolamide 28
HCl 28
zinc 26
Dexamethasone 26
aluminum 25
glycerol 24
Allergan 23
MMC 23
Pac 23
Diphenhydramine 23
Cardiol 23
PEG 22
Apraclonidine 22
Betaxolol 22
nitrogen 22
TNF 22
dUTP 21
prostaglandin E1 20
5-FU 20
Indomethacin 20
Forskolin 19
tyrosine 19
PGD2 19
leucine 19
ethanol 19
silicon 18
Collagen 17
PEG 17
Metipranolol 17
Brinzolamide 17
silver 16
Isoproterenol 16
iodine 16
NMDA 16
5-HT 16
GABA 15
GABA 15
iron 15
Adenosine 15
6-12 15
Propranolol 15
nitrate 14
Propranolol 13
ACS 13
ACS 13
MTT 12
ICI 12
Levobunolol 12
Carteolol 12
prostacyclin 12
bromide 12
phenol 12
urea 12
PGE 12
NH2 11
N2O 11
GSH 11
Salt 11
MCA 11
GSH 11
serine 11
MCA 11
methionine 11
Optimal 11
A 1 11
Phe 11
Dopamine 11
A 42 10
ETA 10
Topiramate 10
copper 10
Norepinephrine 10
A 3 10
mercury 10
lysine 10
fluorine 10
formaldehyde 9
Tetrahydrocannabinol 9
galactose 9
N-isopropylacrylamide 9
Succinylcholine 9
caffeine 9
cyclopentyl 9
Fluorometholone 9
formaldehyde 9
ADP 9
Arachidonic acid 8
Cyclosporine 8
Mannitol 8
chromium 8
ADP 8
Mannitol 8
H2O2 8
ADP 8
Carbachol 8
NAD 8
Ethacrynic acid 7
DBP 7
HMM 7
cysteine 7
tetraphosphate 7
Off 7
carbonate 7
titanium 7
threonine 7
DBP 7
Hematoxylin 7
manganese 7
Neuronal 7
sodium chloride 7
GMP 7
Ethacrynic acid 7
acetic acid 7
proline 7
Angiotensin II 7
Calcitonin 7
Glutamate 7
Dipivefrin 6
benzenesulfonamide 6
Sodium 6
more...