Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0546837 (esophageal cancer)
8,907 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 568
Mol 317
p53 302
TNM 153
nodal 143
caspase-3 97
FDG 92
cyclin D1 87
Bcl-2 82
AKT 77
E-cadherin 76
epidermal growth factor receptor 74
mTOR 55
PI3K 54
She 52
p21 50
vascular endothelial growth factor 50
cytokine 45
cage 45
albumin 43
EGFR 42
catenin 41
ERK 41
aldehyde dehydrogenase 40
serum albumin 40
SCC 38
cyclooxygenase-2 38
carcinoembryonic antigen 36
UTR 35
proliferating cell nuclear antigen 33
HER2 33
MAPK 33
p16 33
histone 33
C-reactive protein 33
kit 32
COX-2 31
epidermal growth factor 31
CRT 31
CCK 31
PARP 30
VEGF 29
ALDH2 29
hemoglobin 29
survivin 28
CD8 28
cancer susceptibility 28
IL-6 27
tyrosine kinase 27
tumor necrosis factor 27
Ki-67 25
insulin 25
MRI 25
HLA 25
proton pump 25
annexin V 24
candidate tumor suppressor 24
caspase-9 24
GSTM1 23
EGF 23
ERK1 23
TNF 23
CEA 23
interferon 23
PD-1 22
interleukin-6 22
ubiquitin 22
c-myc 22
PD-L1 22
Gen 22
N-cadherin 21
beta-catenin 21
p38 20
GSTT1 20
Cyclin D1 20
collagen 20
DCF 20
vimentin 20
ATP 19
bcl-2 19
more...
Disease
esophageal cancer 8907
esophageal cancer 8227
cancer 4388
tumor 2758
squamous cell carcinoma 1536
carcinoma 1007
adenocarcinoma 939
Esophageal 810
gastric cancer 706
metastases 612
Esophagus 612
Esophagus 612
carcinogenesis 459
dysphagia 426
lung cancer 403
Barrett's esophagus 381
Esophageal squamous cell carcinoma 337
dysplasia 296
breast cancer 258
colorectal cancer 253
tumorigenesis 231
tumor progression 210
tumor growth 206
gastroesophageal reflux disease 177
pancreatic cancer 173
pneumonia 172
carcinoma of the esophagus 170
primary tumor 165
esophagitis 163
colon cancer 140
liver cancer 129
hepatocellular carcinoma 125
liver cancer 114
head and neck cancer 113
gastrointestinal cancer 110
Esophageal adenocarcinoma 104
prostate cancer 96
melanoma 90
cervical cancer 87
malnutrition 78
obesity 77
lymphoma 72
bladder cancer 67
rectal cancer 66
leukemia 65
residual disease 64
achalasia 64
neutropenia 60
ovarian cancer 56
celiac disease 54
non-small cell lung cancer 54
sepsis 51
diabetes 49
esophageal stricture 47
sepsis 47
anemia 45
cirrhosis 44
West 41
respiratory failure 39
leukopenia 37
metastatic esophageal cancer 36
carcinoma in situ 36
recurrent esophageal cancer 35
depression 35
oral cancer 34
thrombocytopenia 34
Adenocarcinoma 32
chylothorax 31
liver metastases 30
renal cell carcinoma 30
reflux esophagitis 30
renal cancer 29
laryngeal cancer 29
glioma 28
Chemoradiation 28
thyroid cancer 28
Thoracic 27
laryngeal cancer 27
myelosuppression 27
ischemia 26
more...
Symptom
pain 100
vomiting 62
anesthesia 56
dyspnea 49
nausea 48
diarrhea 46
anorexia 42
fatigue 38
cough 35
discomfort 29
discomfort 28
chest pain 25
nausea and vomiting 24
abdominal pain 23
analgesia 20
respiratory distress 20
cachexia 18
hoarseness 16
weakness 16
heartburn 16
epigastric pain 15
regurgitation 15
overweight 15
flushing 11
hemoptysis 10
acidity 6
headache 6
insomnia 5
colic 5
paresis 5
collapse 5
numbness 5
abdominal fullness 4
back pain 4
exhaustion 4
shortness of breath 4
sleepiness 3
Ill 3
flank pain 3
asthenia 3
functional recovery 3
hypothermia 3
erythema 3
decreased appetite 3
splenomegaly 3
hemiplegia 3
stridor 3
tremor 3
constipation 3
polyuria 2
belching 2
sore throat 2
seizures 2
Wind 2
hypoproteinemia 2
spasm 2
wheezing 2
chills 2
ENT 2
hepatosplenomegaly 2
starvation 2
orthopnea 2
angina 2
agitation 2
halitosis 2
paresthesia 2
dizziness 2
chyluria 1
drooling 1
torticollis 1
despair 1
otalgia 1
inanition 1
HSA 1
bradypnea 1
Fluctuation 1
memory loss 1
excessive sweating 1
stomach distension 1
Mills 1
more...
Drug
Cardiovasc 153
ascorbate 32
Monit 29
Lugol 26
vitamin E 24
Indomethacin 20
Docetaxel 20
lysine 17
ROS 17
Irinotecan 13
IL-2 13
Taxol 12
Photofrin 11
ROC 9
Herceptin 9
BLM 9
IFN-gamma 8
ADM 7
G-CSF 7
ALA 7
niacin 6
Glutathione 6
Photofrin II 6
Hypaque 6
CPT-11 6
Taxotere 6
Lipiodol 6
Adriamycin 5
G418 5
CSF 5
Leaf 5
Ethanol 5
balanced salt solution 5
Lugol's solution 5
Dermatol 5
Vindesine 4
Gefitinib 4
Cetuximab 4
MRC 4
GEO 4
ADR 4
VCR 4
Vindesine 4
CTX 3
Activin 3
CAM 3
Vitamin E 3
NAG 3
CTC 3
CTX 3
TAT 3
Retinoic acid 3
ABC 3
Bevacizumab 3
CTX 3
VCR 3
Vinorelbine 3
Serum albumin 3
ENT 3
Amifostine 3
nitroglycerin 3
Celebrex 3
CTC 3
IL-1ra 3
Etoposide 3
Areca 3
Mutagen 2
Leucovorin 2
caffeine 2
Albumin 2
Asn 2
ACT 2
uPA 2
citric acid 2
AGG 2
Paraffin 2
Hakka 2
Flavopiridol 2
IPM 2
Vitamin A 2
more...
Enzyme
ERK 146
mitogen-activated protein kinase 86
caspase-3 79
luciferase 71
aldehyde dehydrogenase 41
aldehyde dehydrogenase 41
aldehyde dehydrogenase 40
aldehyde dehydrogenase 40
aldehyde dehydrogenase 40
focal adhesion kinase 37
protein kinase 35
PARP 33
reverse transcriptase 30
MEK 26
APC 21
caspase-9 21
DCF 20
glutathione S-transferase 19
alcohol dehydrogenase 18
proteasome 18
protein kinase C 15
peroxidase 14
caspase-8 11
superoxide dismutase 10
dihydropyrimidine dehydrogenase 9
thymidylate synthase 9
thymidine kinase 9
ornithine decarboxylase 9
urokinase-type plasminogen activator 9
cdc2 8
ATPase 8
alanine aminotransferase 7
DNA methyltransferase 7
caspase-7 7
phosphoinositide 3-kinase 7
gamma-glutamyl transpeptidase 7
caspase-7 7
AMP-activated protein kinase 7
GSK 6
NQO1 6
ACS 6
alkaline phosphatase 6
catalase 6
topoisomerase 6
succinate dehydrogenase 6
RNA polymerase 6
methylenetetrahydrofolate reductase 5
demethylase 5
P-glycoprotein 5
AMPK 5
dihydropyrimidine dehydrogenase 5
SNO 5
topoisomerase 5
ceruloplasmin 5
PAH 5
matrix metalloproteinase 2 5
methylenetetrahydrofolate reductase 5
DNA polymerase 5
plasmin 5
IKK 5
glutathione peroxidase 5
AMPK 5
neutrophil elastase 5
trypsin 4
polo-like kinase 1 4
ADH3 4
glutathione reductase 4
ALDH 4
TSA 4
collagenase 4
elastase 4
monoamine oxidase 3
GRK2 3
hypoxanthine-guanine phosphoribosyltransferase 3
NADPH oxidase 3
NADPH oxidase 3
transcriptase 3
RNase 3
RNase 3
lactate dehydrogenase 3
more...
Compound
Clin 591
Dec 588
DNA 501
5-FU 207
TNM 153
MTT 124
water 105
oxygen 98
ethanol 95
Pac 71
glucose 69
iodine 68
barium 58
zinc 57
DDP 50
sodium 42
arginine 39
SCC 38
calcium 38
aldehyde 37
selenium 31
His 31
iron 31
acetaldehyde 30
tyrosine 28
lysine 27
nitrogen 24
bromide 24
Paclitaxel 24
TNF 23
phosphate 23
retinol 23
BLM 23
hydrogen 22
galactose 21
serine 21
nitrate 20
ATP 19
creatinine 19
acetate 19
retinoic acid 19
alcohol dehydrogenase 18
copper 18
GSH 18
CO2 18
GSH 18
glutamine 18
MEK 18
Optimal 17
Docetaxel 16
PDT 15
ASA 15
MMC 15
methionine 15
FAP 14
pyrene 14
FAP 14
sulfate 13
A 71 12
vitamin D 11
alanine 11
N-acetylcysteine 11
aluminum 11
nitric oxide 11
cysteine 11
fluorine 11
Vimentin 11
salt 11
Phe 11
Ile 10
aldehyde 10
valine 10
molybdenum 10
threonine 10
DEN 10
urea 9
formaldehyde 9
silver 9
nickel 9
NH2 8
more...