Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0497406 (overweight)
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Human Gene/Protein
FLJ39370 10.2
ATPase type 13A4 10.2
OR7G3 9.2
CNTD 9.2
NYD-SP18 9.2
insulin induced gene 2 8.9
Zic family member 4 8.7
Pre-B-cell leukemia transcription factor 1 8.7
OR7E24 8.7
MME protein 8.7
transmembrane protein 18 8.7
ZNF134 8.7
OR12D3 8.7
cell death-inducing DFFA-like effector a 8.2
OR8U8 8.2
ERO1LB 8.2
FAM120AOS 8.2
MRPS18B 8.2
ZNF577 8.2
BIKE 8.0
calcium binding protein 39 7.9
P2RX5 7.9
WDTC1 7.9
INCA1 7.8
Glutathione S-transferase kappa 1 7.7
ZFAND5 7.7
apolipoprotein B48 receptor 7.7
fructose-bisphosphate aldolase C 7.5
IL-15RA 7.4
DNAJC27 7.4
ORMDL1 7.4
NPTN 7.4
INTS4 7.4
CCNT2 7.4
BIA1 7.4
GPX6 7.4
SEC16B 7.4
AK1 protein 7.2
ZNF608 7.2
TMEM26 7.2
TREH 7.2
NBEAL1 7.2
TMEM18 7.1
PARF 7.1
dishevelled-associated activator of morphogenesis 1 7.1
TMEM207 7.1
YCL1 7.1
TULP2 7.1
HSD11 7.1
TUBB5 6.9
SNTG2 6.9
COL23A1 6.9
KCTD15 6.9
COL24A1 6.8
MONA 6.8
CMTM7 6.8
SLC22A17 6.8
Zfp191 6.8
L13A 6.8
calmodulin-binding transcription activator 1 6.7
homeobox B5 6.7
SLN protein 6.7
HSA8 6.7
Nucleobindin-2 6.6
KCNH8 6.5
PPM2 6.5
MOGAT1 6.5
EIF3A 6.5
MPP-9 6.5
ATP6B1 6.5
delta-9-desaturase 6.5
SPRING 6.5
PTER 6.4
MYL6 6.4
KCTD13 6.4
INSIG2 6.4
MBOAT7 6.4
QPCTL 6.3
MEP1A 6.3
PRRP 6.3
more...
Disease
Drug-induced obesity 10.2
Distorted visual perception 10.2
Steatopygia 10.2
Other eating disorders 10.2
Overweight and obesity 9.6
Mild pre-eclampsia 9.2
Subclavian Steal 9.2
Scalloped tongue 9.2
Adult atopic dermatitis 8.7
Adult-onset obesity 8.7
Child Malnutrition 8.7
Generalized obesity 8.5
Gastrointestinal ulcer 8.2
Diabetic fetopathy 7.9
PSYCHOSOCIAL 7.9
Primary empty sella syndrome 7.9
Alimentary obesity 7.9
Other endocrine disorders 7.9
Diuretic abuse 7.9
Hypertrophic obesity 7.9
moderate obesity 7.8
Simple obesity 7.7
WAGRO 7.7
Other liver diseases 7.7
Periductal mastitis 7.7
Asthma, hay 7.4
Combined hyperlipidemia 7.4
Glomerulonephropathy 7.4
abdominal obesity 7.4
Floppy eyelid syndrome 7.3
Breast infections 7.2
Adult celiac disease 7.2
overnutrition 7.2
compulsive overeating 7.2
obesity 7.1
Precocious pubarche 7.1
Android obesity 7.1
Prehypertension 7.0
Body image disturbance 7.0
appetite disorder 6.9
Post-traumatic hypopituitarism 6.9
MONA 6.8
WHSCR 6.7
Adenomatosis 6.4
Autonomic imbalance 6.4
Arteriolosclerosis 6.4
binge eating 6.4
metabolic syndrome X 6.4
prediabetes 6.4
Premature adrenarche 6.4
Post-pill amenorrhea 6.3
Fetal acidosis 6.3
Genital prolapse 6.3
fetal macrosomia 6.3
Acute viral bronchiolitis 6.2
Hypermobility syndrome 6.2
nutritional disorder 6.2
Venous aneurysm 6.2
Diabetes and Pregnancy 6.1
Pseudotumor cerebri 6.1
Chagas' disease cardiomyopathy 6.1
hyperphagia 6.1
Self-induced vomiting 6.0
Chronic thyroiditis 6.0
Disseminated cancer 6.0
metabolic syndrome 5.9
morbid obesity 5.9
allergic bronchitis 5.8
diastolic hypertension 5.8
gestational diabetes mellitus 5.8
bulimia nervosa 5.8
Mild depression 5.8
Plaque psoriasis 5.8
dyslipidemia 5.8
borderline hypertension 5.8
Neutrophil dysfunction 5.7
LMS 5.7
LMS 5.7
BED 5.7
Falsification 5.7
more...
Symptom
overweight 10.2
weight problem 8.8
High weight 7.9
Carbohydrate craving 7.9
Dysdiadochokinesis 7.9
Nausea, vomiting and diarrhea 7.7
corpulence 7.6
Stomach fullness 7.2
feeling of choking 6.9
feeling exhausted 6.3
Hypersomnolence 6.2
hypnagogic hallucination 6.2
hunger 6.1
GI pain 6.0
skin impairment 5.8
vaginal discomfort 5.8
workaholic 5.4
feeling sick 5.4
mouth pain 5.3
feeling depressed 5.3
brittle nails 5.2
Mechanical pain 5.2
reproductive problem 5.1
Self-neglect 5.0
stomach distension 4.9
Decreased activity 4.8
Functional abdominal pain 4.7
physical appearance 4.7
Foot pain 4.7
Multimorbidity 4.7
snoring 4.5
Pain symptoms 4.4
Functional constipation 4.3
female puberty 4.3
Depressive symptoms 4.2
feeling tired 4.0
heel pain 3.9
male puberty 3.8
Spotting 3.8
male subfertility 3.8
Periodic breathing 3.8
Poor sleep 3.7
stigma 3.7
decreased appetite 3.5
nerve pain 3.5
Visual disturbances 3.4
nocturnal cough 3.4
bewilderment 3.4
knee pain 3.2
Catch 3.2
hypersomnia 3.2
ketonuria 3.1
hyperemesis 3.0
menometrorrhagia 3.0
iliac fossa pain 2.9
thirsty 2.9
physical exhaustion 2.9
acid regurgitation 2.9
emaciation 2.8
sleepiness 2.8
peri-menopausal 2.7
Regurgitation 2.7
arm weakness 2.7
Lower urinary tract symptoms 2.7
chronic back pain 2.7
excessive sweating 2.6
irregular bleeding 2.6
Gastrointestinal symptoms 2.6
generalized pain 2.6
Fluctuation 2.6
menopausal symptoms 2.6
wheezing 2.5
abnormal breathing 2.5
inanition 2.4
disturbed balance 2.4
Wind 2.3
constipation 2.3
Stiffness 2.3
auditory hallucination 2.2
swollen joints 2.2
more...
Drug
Cynt 9.2
Meridia 8.8
Dirlotapide 8.8
Sergliflozin 7.9
APD-356 7.4
Meridia 7.2
Orlistat 6.9
Rimonabant 6.6
Dexfenfluramine 6.6
Symlin 6.5
Caraway 6.5
Nux vomica 6.3
Ganirelix 6.2
Quantum II 6.0
Amaryl 6.0
Myo-Inositol 5.9
Alfaprostol 5.8
Liraglutide 5.7
Lipoic Acid 5.7
ULR 5.4
Benzylamine 5.4
Rize 5.3
Diethylpropion 5.2
Aescin 5.2
Polydextrose 5.1
Mazindol 5.0
Exenatide 4.9
CEG 4.7
Somatropin 4.7
Avandia 4.7
CEG 4.5
Syrup 4.5
Frovatriptan 4.5
Tham 4.4
Cortrosyn 4.3
Pramlintide 4.2
Cortrosyn 4.0
Maxon 3.9
Hakka 3.9
Domin 3.8
Rasburicase 3.8
Valproic Acid 3.7
Polydioxanone 3.7
Pegasys 3.7
niacin 3.7
Sodium benzoate 3.6
Rosiglitazone 3.6
Coconut oil 3.6
GHRP 3.4
Android 3.4
Fluticasone propionate 3.4
Efalizumab 3.4
Gliclazide 3.4
Efalizumab 3.4
Sodium alginate 3.3
Lutalyse 3.3
Anidulafungin 3.2
Bezafibrate 3.1
Ximelagatran 3.1
Vitamin K2 3.0
Ezetimibe 3.0
Corn oil 3.0
Acamprosate 3.0
Soybean oil 3.0
CVA 2.9
Clomiphene citrate 2.9
Lactic Acid 2.9
Calcipotriol 2.9
Monosodium glutamate 2.9
Glucagon 2.9
Depo-Provera 2.9
Colombo 2.9
Perindopril 2.9
Fructose 2.8
ADM 2.8
Monarch 2.8
Serum albumin 2.8
APM 2.7
Check 2.7
Bifidobacterium 2.7
more...
Enzyme
EC 2.8.3.9 7.9
CYP39A1 6.1
serum carnosinase 5.4
AOR 5.0
FADS 4.6
methionine synthase reductase 4.2
5beta-reductase 4.0
IOR 4.0
butyrate kinase 3.8
phosphomevalonate kinase 3.6
paraoxonase 3.4
CYP7B1 3.3
SOR 3.3
HOA 3.2
phosphoserine phosphatase 3.2
guanidinoacetate methyltransferase 3.1
hormone-sensitive lipase 3.0
glycine amidinotransferase 2.9
LPL 2.8
paraoxonase 2.8
NAO 2.8
alanine aminotransferase 2.7
lipoprotein lipase 2.7
MCS 2.6
21-hydroxylase 2.6
17beta-HSD 2.6
HCS 2.6
methylenetetrahydrofolate reductase 2.5
methylenetetrahydrofolate reductase 2.5
PRE 2.5
gamma-glutamyl transpeptidase 2.5
phosphatidylethanolamine N-methyltransferase 2.4
RGP 2.4
lactonase 2.4
AMP-activated kinase 2.4
fatty acid desaturase 2.4
DMT 2.3
PHT 2.3
AST 2.3
alpha-glucosidase 2.2
aspartate aminotransferase 2.2
indoleamine 2,3-dioxygenase 2.1
fumarylacetoacetate hydrolase 2.1
diacylglycerol acyltransferase 2.0
glycerophosphate acyltransferase 1.9
AMPK 1.9
tryptophanyl-tRNA synthetase 1.9
inulinase 1.9
MsrA 1.9
levansucrase 1.9
GMT 1.8
monoacylglycerol lipase 1.8
17beta-HSD 1.8
caspase-11 1.8
caspase-11 1.8
E-2 1.8
inulinase 1.8
SOR 1.7
ornithine aminotransferase 1.7
ceruloplasmin 1.7
renin 1.7
AGT 1.6
prostate-specific antigen 1.6
CFI 1.6
TMT 1.6
carboxypeptidase E 1.6
citrate synthase 1.6
BAT 1.5
11beta-hydroxysteroid dehydrogenase 1.5
tissue plasminogen activator 1.5
AMP-activated protein kinase 1.5
CAD 1.5
CAD 1.5
CAD 1.4
ACE 1.4
CPT 1.4
chymosin 1.4
cholesterol esterase 1.4
BIS 1.3
glucokinase 1.3
more...
Compound
EA 68 10.2
Trihexosylceramide 8.2
RC-16 7.7
N-acetylvaline 7.7
RC-16 7.7
Fagomine 7.5
Sibutramine 7.4
Phentermine 7.4
Phendimetrazine 7.2
2-hydroxyoctanoic acid 6.9
GP 47779 6.8
heptonic acid 6.7
T undecanoate 6.4
p-Synephrine 6.3
Fastin 6.2
Diethylpropion 5.8
FMI 5.8
HEI 5.6
NCD 5.5
Benzylamine 5.3
Acar 5.3
Anserine 5.2
2,5-DCP 5.2
Infecundin 5.2
Nicotinamide riboside 5.1
27-Hydroxycholesterol 5.0
Metformin 5.0
Tributyltin chloride 5.0
Metformin 5.0
Oleoylethanolamide 4.9
EPA ethyl ester 4.9
Acarbose 4.7
DBP 4.7
2,5-dichlorophenol 4.6
Coprostanol 4.6
S-15 4.6
IBP 4.5
IBP 4.5
DBP 4.5
Loxapine 4.5
X 18 4.5
SD 25 4.4
ONT 4.4
N-acetyltryptophan 4.4
PTSM 4.4
Oxandrolone 4.4
Sucralose 4.3
Desogestrel 4.3
MOD 4.3
N-acetyltryptophan 4.3
DSE 4.3
N6-Methyladenosine 4.2
AAQ 4.2
Synephrine 4.2
PAPP 4.1
Fenfluramine 4.1
Insulin 4.1
Glimepiride 4.0
Topiramate 4.0
CHNS 4.0
Escin 4.0
PAPP 4.0
Escin 4.0
Moxonidine 3.9
Cantril 3.9
Levulinic acid 3.9
CHNS 3.9
CHNS 3.9
A 99 3.8
CHNS 3.8
Allopregnanolone 3.8
N'-methylnicotinamide 3.8
Fructosamine 3.8
Guanidinoacetic acid 3.7
PGE3 3.7
Clomiphene 3.7
UPP 3.7
DPP 3.7
Allopregnanolone 3.6
Semicarbazide 3.6
more...