Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0476273 (respiratory distress)
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Human Gene/Protein
latent transforming growth factor-beta binding protein 4 10.7
TRBV12-4 10.7
IGHMBP2 10.0
chromosome 9 open reading frame 116 9.7
FAP68 9.7
TRBV15 9.7
KIAA0317 9.7
ATP-binding cassette sub-family A member 3 9.4
RNFT2 9.1
TRBV30 9.1
PN-II 8.9
Transient receptor potential cation channel, subfamily V, member 6 8.7
dynein axonemal intermediate chain 8.5
Surfactant protein B 8.5
CCDC151 8.3
ABT1 8.3
CNRG 8.3
activator of basal transcription 1 8.3
purine-rich element binding protein A 8.3
N-heparan sulfate sulfotransferase 8.3
MEGF10 8.3
ABCA3 8.2
Midline-1 8.1
HOXA5 protein 8.1
SP-B 8.0
SP-C 7.9
TMC3 7.9
HECTD2 7.9
pulmonary surfactant apoprotein 7.9
MBIP 7.9
MGA protein 7.9
ASCC1 7.9
RAPGEF6 7.9
EVC1 7.9
RDS 7.8
SPAG17 7.8
CALR protein 7.7
SFTA3 7.7
SP-A1 7.5
RSPH1 7.5
DBN1 7.5
Activating signal cointegrator 1 7.5
CREB1 protein 7.5
RCN2 7.5
cysteine/histidine-rich 1 7.5
SLC25A26 7.5
SLC25A1 7.4
microtubule-actin crosslinking factor 1 7.3
TRIP4 7.3
ABCA3 protein 7.3
surfactant protein B 7.2
FBXO3 7.2
surfactant protein A1 7.2
PLA2G4D 7.2
ARMC4 7.2
Histone acetyltransferase 1 7.2
SPAG16 7.2
WDR35 7.1
TLT-1 7.1
SP-A 7.1
LYRM7 7.1
CC2D1B 7.1
YT35 7.1
focal adhesion kinase 1 7.1
MMADHC 7.1
surfactant protein C 7.0
RSPH4A 7.0
G5PR 7.0
eppin 7.0
XKR6 6.9
DOK3 6.9
endosomal adaptor protein 6.9
GCSH 6.9
SP-A2 6.9
matrix metalloproteinase 16 6.9
GSKIP 6.9
TTC19 6.8
serine/threonine kinase 40 6.8
Trypsin-2 6.8
claudin 18 6.8
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Disease
lacrimal disorder 10.7
Single organ dysfunction 10.7
diffuse adenocarcinoma of the stomach 10.7
Iatrogenic hypothyroidism 10.7
larynx; thickening 10.7
Chronic pulmonary insufficiency of prematurity 10.7
Acute subendocardial infarction 10.7
Atypical interstitial pneumonia 10.7
Lycoperdonosis 10.7
Laryngeal cyst 10.7
syndrome; 49 10.7
Congenital central alveolar hypoventilation syndrome 10.7
Haemophilus sepsis 10.7
SMARD1 10.6
Neonatal respiratory distress 10.3
meconium aspiration pneumonia 10.2
Congenital pulmonary lymphangiectasis 10.0
Pulmonary pneumatocele 9.7
Anaphylactoid syndrome of pregnancy 9.7
Interstitial pulmonary emphysema 9.7
Complete atelectasis 9.7
Subglottis 9.7
Quail bronchitis 9.7
Mixed malaria 9.7
Brooks syndrome 9.7
Acute silicosis 9.7
Multiple lung abscesses 9.7
Pulmonary bulla 9.7
Transient tachypnea of newborn 9.4
Hemorrhagic pleural effusion 9.3
Obstructive emphysema 9.3
Acute respiratory distress 9.3
Neonatal listeriosis 9.2
Vallecula 9.1
Hyper-beta-alaninemia 9.1
Idiopathic arterial calcification of infancy 9.1
Group B streptococcal pneumonia 9.1
ACG1B 9.1
Acute cor pulmonale 9.1
Camptomelic dysplasia 9.1
pneumopyothorax 9.1
CED2 9.1
Nocardia sepsis 9.1
Pneumococcal peritonitis 9.1
Stress induced cardiomyopathy 9.1
Pulmonary immaturity 9.1
Inherited cutis laxa 9.1
Toxic pulmonary oedema 9.1
Interstitial emphysema 9.1
Primary pulmonary hypoplasia 9.1
Bronchial compression 8.9
Diffuse alveolar damage 8.9
Wilson-Mikity syndrome 8.9
uremic pneumonitis 8.9
Distal spinal muscular atrophy 8.9
Congenital tuberculosis 8.8
Transfusion related acute lung injury (TRALI) 8.8
Congenital candidiasis 8.8
Lupus pneumonitis 8.7
Listeria septicemia 8.7
Open pneumothorax 8.7
Epiglottic cyst 8.7
Amnionitis 8.7
Congenital chylothorax 8.7
Iododerma 8.7
Early onset neonatal sepsis 8.7
Rotaviral infections 8.7
von Jaksch 8.7
Pulmonary adiaspiromycosis 8.7
Pulmonary microemboli 8.7
Laryngeal obstruction 8.5
Transfusion-related acute lung injury 8.5
Staphylococcal pneumonia 8.5
Neonatal respiratory distress syndrome 8.5
Tetralogy of Fallot with absent pulmonary valve 8.4
Meconium aspiration syndrome 8.4
Congenital pneumonia 8.3
Hydrallantois 8.3
GM1 gangliosidosis, type 1 8.3
Laryngeal web 8.3
more...
Symptom
respiratory distress 10.7
Drug-induced pruritus 10.7
Trepopnea 8.7
Expiratory wheezing 8.7
Diaphragmatic flutter 8.7
Polypnea 8.7
Opisthotonus 8.0
Respiratory abnormalities 7.9
Monoparesis 7.9
Inspiratory stridor 7.9
stridor 7.7
Central cyanosis 7.7
Fetal tachycardia 7.7
respiratory problem 7.6
tachypnea 7.5
Respiratory dyskinesia 7.3
chest restriction 7.3
Chills and fever 7.3
Apneusis 7.2
Acute edema 7.1
abnormal breath sounds 7.1
cyanosis 7.0
Massive edema 6.8
musculoskeletal chest pain 6.7
S3 gallop 6.6
Very Low Birth Weight 6.6
benign congenital hypotonia 6.5
Flaccid paralysis 6.5
Air trapping 6.4
Organ failure 6.3
prostration 6.2
rales 6.1
muscular incoordination 6.1
dyslalia 6.1
Diarrhea and vomiting 6.1
Poor weight gain 6.0
change in skin color 6.0
feeling sick 5.8
labored breathing 5.8
Acute dyspnea 5.7
pleuritic chest pain 5.6
nasal discharge 5.5
retrosternal discomfort 5.5
breast hyperplasia 5.5
Orthostasis 5.5
non-productive cough 5.5
aphonia 5.5
Respiratory symptoms 5.5
wheezing 5.5
hoarseness 5.4
cough 5.4
hypercapnia 5.3
sore throat 5.3
shortness of breath 5.2
hyperoxia 5.2
throat irritation 5.2
dyspnea 5.1
carpopedal spasm 5.1
hemoptysis 5.1
loss of equilibrium 5.1
productive cough 5.1
hypotonia 5.1
lethargy 5.0
abnormal breathing 4.9
thoracic back pain 4.9
cardiovascular impairment 4.9
oliguria 4.9
Flu-like symptoms 4.9
orthopnea 4.8
drooling 4.7
loss of taste 4.7
Physical findings 4.6
bradypnea 4.6
hepatosplenomegaly 4.5
diastolic murmurs 4.5
Urinary symptoms 4.4
voice change 4.4
pallor 4.4
nasal congestion 4.3
prominent nose 4.3
more...
Drug
Colfosceril palmitate 10.7
Lucinactant 10.0
Surfacten 9.7
Metrenperone 9.7
Survanta 9.0
Dimexidum 8.7
Calfactant 8.7
Yutopar 8.1
Yutopar 8.1
Loxonin 7.9
Alloferin 7.7
Sivelestat 7.4
Dexamethasone palmitate 7.3
Seratrodast 7.3
Imagent 7.2
Flolan 7.2
TFLX 7.1
Flolan 7.1
Sivelestat sodium hydrate 7.1
FLM 7.0
Ches 7.0
Lisofylline 6.9
Pulmozyme 6.9
Calcifediol 6.9
Selenium sulfide 6.9
Quinidine sulfate 6.7
Thymalfasin 6.6
Myo-Inositol 6.3
Blenoxane 6.3
Roferon A 6.3
Ethamsylate 6.2
Atosiban 6.0
Meconium 5.9
Hirudoid 5.9
Minocin 5.9
Tocilizumab 5.8
Myozyme 5.8
Ventolin 5.6
Ludiomil 5.5
Ludiomil 5.5
Tosufloxacin 5.3
Peramivir 5.3
Interferon alfa-2a 5.3
Cilomilast 5.3
Gentian violet 5.2
Magnesium sulfate 5.2
Ozagrel 5.2
Pralidoxime 5.0
Crotonaldehyde 5.0
Talc 4.9
Beraprost 4.9
Barium sulfate 4.9
Singulair 4.9
Ulinastatin 4.8
Indoramin 4.8
LVFX 4.8
Lornoxicam 4.8
Oseltamivir 4.7
Nafamostat mesilate 4.7
Anakinra 4.7
MEPM 4.7
Ketalar 4.6
Chlorothiazide 4.6
Kaletra 4.6
Malarone 4.6
Gamma globulin 4.6
Amoxapine 4.6
Sesame oil 4.6
Argatroban 4.4
Drotrecogin alfa 4.4
Relenza 4.4
Maxon 4.4
Drotrecogin alfa 4.4
Methyldopa 4.4
Telbivudine 4.3
Cibenzoline 4.3
Beta-2 4.3
Dazoxiben 4.3
7-Nitroindazole 4.2
Cidofovir 4.2
more...
Enzyme
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase 8.1
angiotensin-converting enzyme 2 6.5
lysophosphatidylcholine acyltransferase 5.0
BAL 4.6
neutrophil elastase 4.5
3-hydroxy-3-methylglutaryl-CoA lyase 4.4
isovaleryl-CoA dehydrogenase 4.1
CDH 4.1
nicotinamide phosphoribosyltransferase 3.7
methylmalonyl-CoA mutase 3.6
choline kinase 3.5
ATP diphosphohydrolase 3.4
MIP 3.2
neutrophil collagenase 3.1
biotinidase 3.0
PIP kinase 3.0
elastase 2.9
ancrod 2.9
oxytocinase 2.8
E-2 2.8
sphingomyelin synthase 2.8
PPH 2.7
HVS 2.7
SOR 2.7
ADP-ribosyltransferase 2.7
Hageman factor 2.7
AGT 2.7
APC 2.6
ADP-ribosyltransferase 2.6
biliverdin reductase 2.5
ricin 2.5
prolyl hydroxylase 2.4
ACE 2.3
neutral sphingomyelinase 2.3
type III procollagen 2.2
tissue plasminogen activator 2.2
peptidylarginine deiminase 2.2
phospholipase A2 2.1
isoamylase 2.1
soluble epoxide hydrolase 2.1
sphingosine kinase 2.1
thromboplastin 2.1
myosin light chain kinase 2.1
transaldolase 2.0
lecithin:cholesterol acyltransferase 2.0
chymopapain 2.0
xanthine dehydrogenase 2.0
lysyl oxidase 2.0
creatine kinase 1.9
TSP-1 1.9
11beta-hydroxysteroid dehydrogenase 1.9
chymopapain 1.9
Protein 2 1.9
matrix metalloproteinase 9 1.9
thrombin 1.8
cathepsin G 1.8
SCP 1.8
lactate dehydrogenase 1.8
kallikrein 1.8
caspase-6 1.8
GAS 1.8
CPT 1.7
renin 1.7
caspase-6 1.7
apyrase 1.7
xanthine oxidase 1.6
peroxidase 1.6
urokinase-type plasminogen activator 1.6
SPT 1.6
PCP 1.6
CNPase 1.6
cholinesterase 1.6
meprin 1.5
thromboxane synthase 1.5
caspase-1 1.5
MTD 1.4
neuraminidase 1.4
dihydropyrimidine dehydrogenase 1.4
arylsulfatase A 1.4
PAM 1.4
more...
Compound
Gynipral 9.1
Alodan 9.1
Cholesteryl palmitate 8.1
T 39 7.7
BG 1 7.7
3-Chlorotyrosine 7.7
1-Nitronaphthalene 7.5
6,10-dimethyl-5,9-undecadien-2-one 7.5
Prone 7.5
Diazoaminobenzene 7.2
ethyl methylcarbamate 7.2
Nivaquine 7.1
C8H18 6.8
Propylhexedrine 6.7
Cyclocytidine 6.7
Ruscogenin 6.5
Complement factor B 6.5
Quinidine sulfate 6.4
Dequalinium chloride 6.4
Betamethasone 6.3
Metaproterenol 6.2
Toce 6.1
3 PS 6.1
Tolazoline 6.0
1,4-phthalazinedione 6.0
Methyl isocyanate 6.0
Ritodrine hydrochloride 6.0
Octyl gallate 5.9
Hordenine 5.9
DOTC 5.9
Sudan Red 7B 5.8
trichloroacetyl chloride 5.7
Complamin 5.6
Oseltamivir phosphate 5.6
Zinc chloride 5.5
Dolin 5.5
Minocycline hydrochloride 5.5
Ethyl pyruvate 5.4
Penciclovir 5.4
Cresol 5.4
Bismuth subsalicylate 5.4
Melarsoprol 5.3
Benzocaine 5.3
Magnesium sulfate 5.1
Hydroxocobalamin 5.1
Fosphenytoin 5.0
Pralidoxime 5.0
Magnesium sulfate 5.0
Daphnetin 5.0
Zanamivir 5.0
Oseltamivir 5.0
Sudan I 4.9
VCC 4.8
Beclomethasone 4.8
Sodium cyanide 4.8
Nitrofen 4.8
Diosmetin 4.7
Ipratropium 4.7
3-methylindole 4.7
DPPC 4.7
Ritodrine 4.6
DPPC 4.6
X 14 4.6
Pancuronium 4.5
Xanthine 4.5
Argatroban 4.4
Carbimazole 4.4
Guo 4.4
20-OH-LTB4 4.4
Hydroxychloroquine 4.4
Cromolyn 4.3
Cidofovir 4.3
Resiniferatoxin 4.3
Punicalagin 4.2
1-Methyl-4-phenylpyridinium 4.2
20-COOH-LTB4 4.2
Cepharanthine 4.2
Paraquat 4.1
Trifluorothymidine 4.1
beta-Glucan 4.1
more...