Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0476273 (respiratory distress)
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Human Gene/Protein
latent transforming growth factor-beta binding protein 4 10.7
TRBV12-4 10.7
IGHMBP2 10.0
chromosome 9 open reading frame 116 9.7
TRBV15 9.7
KIAA0317 9.7
FAP68 9.7
ATP-binding cassette sub-family A member 3 9.4
RNFT2 9.1
TRBV30 9.1
PN-II 8.9
Transient receptor potential cation channel, subfamily V, member 6 8.7
dynein axonemal intermediate chain 8.5
Surfactant protein B 8.5
CNRG 8.3
activator of basal transcription 1 8.3
ABT1 8.3
purine-rich element binding protein A 8.3
N-heparan sulfate sulfotransferase 8.3
CCDC151 8.3
MEGF10 8.3
ABCA3 8.2
Midline-1 8.1
HOXA5 protein 8.1
SP-B 8.0
SP-C 7.9
HECTD2 7.9
RAPGEF6 7.9
pulmonary surfactant apoprotein 7.9
TMC3 7.9
EVC1 7.9
ASCC1 7.9
MBIP 7.9
MGA protein 7.9
RDS 7.8
SPAG17 7.8
SFTA3 7.7
CALR protein 7.7
SP-A1 7.5
RSPH1 7.5
more...
Disease
lacrimal disorder 10.7
Acute subendocardial infarction 10.7
Atypical interstitial pneumonia 10.7
Lycoperdonosis 10.7
Haemophilus sepsis 10.7
Iatrogenic hypothyroidism 10.7
syndrome; 49 10.7
diffuse adenocarcinoma of the stomach 10.7
larynx; thickening 10.7
Single organ dysfunction 10.7
Congenital central alveolar hypoventilation syndrome 10.7
Chronic pulmonary insufficiency of prematurity 10.7
Laryngeal cyst 10.7
SMARD1 10.6
Neonatal respiratory distress 10.3
meconium aspiration pneumonia 10.2
Congenital pulmonary lymphangiectasis 10.0
Quail bronchitis 9.7
Interstitial pulmonary emphysema 9.7
Subglottis 9.7
Anaphylactoid syndrome of pregnancy 9.7
Pulmonary bulla 9.7
Pulmonary pneumatocele 9.7
Mixed malaria 9.7
Complete atelectasis 9.7
Multiple lung abscesses 9.7
Brooks syndrome 9.7
Acute silicosis 9.7
Transient tachypnea of newborn 9.4
Obstructive emphysema 9.3
Hemorrhagic pleural effusion 9.3
Acute respiratory distress 9.3
Neonatal listeriosis 9.2
Hyper-beta-alaninemia 9.1
Primary pulmonary hypoplasia 9.1
Nocardia sepsis 9.1
Group B streptococcal pneumonia 9.1
Acute cor pulmonale 9.1
Vallecula 9.1
Pulmonary immaturity 9.1
more...
Symptom
Drug-induced pruritus 10.7
respiratory distress 10.7
Trepopnea 8.7
Expiratory wheezing 8.7
Diaphragmatic flutter 8.7
Polypnea 8.7
Opisthotonus 8.0
Monoparesis 7.9
Respiratory abnormalities 7.9
Inspiratory stridor 7.9
stridor 7.7
Fetal tachycardia 7.7
Central cyanosis 7.7
respiratory problem 7.6
tachypnea 7.5
Chills and fever 7.3
chest restriction 7.3
Respiratory dyskinesia 7.3
Apneusis 7.2
Acute edema 7.1
abnormal breath sounds 7.1
cyanosis 7.0
Massive edema 6.8
musculoskeletal chest pain 6.7
S3 gallop 6.6
Very Low Birth Weight 6.6
benign congenital hypotonia 6.5
Flaccid paralysis 6.5
Air trapping 6.4
Organ failure 6.3
prostration 6.2
rales 6.1
dyslalia 6.1
muscular incoordination 6.1
Diarrhea and vomiting 6.1
Poor weight gain 6.0
change in skin color 6.0
feeling sick 5.8
labored breathing 5.8
Acute dyspnea 5.7
more...
Drug
Colfosceril palmitate 10.7
Lucinactant 10.0
Surfacten 9.7
Metrenperone 9.7
Survanta 9.0
Calfactant 8.7
Dimexidum 8.7
Yutopar 8.1
Yutopar 8.1
Loxonin 7.9
Alloferin 7.7
Sivelestat 7.4
Seratrodast 7.3
Dexamethasone palmitate 7.3
Imagent 7.2
Flolan 7.2
TFLX 7.1
Sivelestat sodium hydrate 7.1
Flolan 7.1
FLM 7.0
Ches 7.0
Lisofylline 6.9
Pulmozyme 6.9
Selenium sulfide 6.9
Calcifediol 6.9
Quinidine sulfate 6.7
Thymalfasin 6.6
Myo-Inositol 6.3
Blenoxane 6.3
Roferon A 6.3
Ethamsylate 6.2
Atosiban 6.0
Meconium 5.9
Minocin 5.9
Hirudoid 5.9
Tocilizumab 5.8
Myozyme 5.8
Ventolin 5.6
Ludiomil 5.5
Ludiomil 5.5
more...
Enzyme
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase 8.1
angiotensin-converting enzyme 2 6.5
lysophosphatidylcholine acyltransferase 5.0
BAL 4.6
neutrophil elastase 4.5
3-hydroxy-3-methylglutaryl-CoA lyase 4.4
isovaleryl-CoA dehydrogenase 4.1
CDH 4.1
nicotinamide phosphoribosyltransferase 3.7
methylmalonyl-CoA mutase 3.6
choline kinase 3.5
ATP diphosphohydrolase 3.4
MIP 3.2
neutrophil collagenase 3.1
biotinidase 3.0
PIP kinase 3.0
elastase 2.9
ancrod 2.9
oxytocinase 2.8
E-2 2.8
sphingomyelin synthase 2.8
PPH 2.7
HVS 2.7
SOR 2.7
ADP-ribosyltransferase 2.7
Hageman factor 2.7
AGT 2.7
APC 2.6
ADP-ribosyltransferase 2.6
biliverdin reductase 2.5
ricin 2.5
prolyl hydroxylase 2.4
ACE 2.3
neutral sphingomyelinase 2.3
type III procollagen 2.2
tissue plasminogen activator 2.2
peptidylarginine deiminase 2.2
phospholipase A2 2.1
isoamylase 2.1
soluble epoxide hydrolase 2.1
more...
Compound
Gynipral 9.1
Alodan 9.1
Cholesteryl palmitate 8.1
T 39 7.7
3-Chlorotyrosine 7.7
BG 1 7.7
6,10-dimethyl-5,9-undecadien-2-one 7.5
1-Nitronaphthalene 7.5
Prone 7.5
Diazoaminobenzene 7.2
ethyl methylcarbamate 7.2
Nivaquine 7.1
C8H18 6.8
Cyclocytidine 6.7
Propylhexedrine 6.7
Complement factor B 6.5
Ruscogenin 6.5
Dequalinium chloride 6.4
Quinidine sulfate 6.4
Betamethasone 6.3
Metaproterenol 6.2
Toce 6.1
3 PS 6.1
Tolazoline 6.0
Methyl isocyanate 6.0
1,4-phthalazinedione 6.0
Ritodrine hydrochloride 6.0
Hordenine 5.9
Octyl gallate 5.9
DOTC 5.9
Sudan Red 7B 5.8
trichloroacetyl chloride 5.7
Oseltamivir phosphate 5.6
Complamin 5.6
Zinc chloride 5.5
Minocycline hydrochloride 5.5
Dolin 5.5
Ethyl pyruvate 5.4
Penciclovir 5.4
Cresol 5.4
more...