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Query: UMLS:C0476273 (respiratory distress)
 19,632 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Pulmonary artery sling is a rare cause of respiratory distress the embryological origin of which is not known. Two patients with this abnormality, both of whom are now thriving, are described. Surgery was necessary at the age of 5 1/2 years in one child, who also had an atrial septal defect. The other child, at the age of 2 years, shows improvement of her wheezing, cough, and breathlessness despite having had neither surgical nor medical treatment.
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PMID:Pulmonary artery sling. 646 17

Congenital laryngeal anomalies are a frequent cause of obstructive dyspnea in neonates and young infants, and raise diagnostic and emergency treatment problems. Clinical symptomatology includes stridor of variable severity, obstructive dyspnea and deglutition disorders, but a less typical picture may be seen of apnea, cyanotic episodes, bradycardia and even cardiac arrests. A retrospective study of 687 case-reports of infants treated between 1974 and 1983 was conducted. Lesions included essential congenital laryngeal stridor (laryngomalacia) in 378 cases (50%), of which 15% were severe with respiratory distress and/or deglutition disorders; laryngeal palsy in 161 cases (23%), bilateral in 56 and unilateral in 105 cases; laryngeal incoordination in 23 cases; laryngeal stenosis: 79 cases (11%) including 58 subglottic and 18 dysphragmatic stenoses and 3 atresias; subglottic hematoma: 49 cases; ary-epiglottic or glosso-epiglottic cyst: 15 cases; laryngeal diastema: 11 cases; and bifid epiglottis: 1 case. Clinical, radiologic and endoscopic findings, and the principal therapies used, are discussed for each anomaly.
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PMID:[Laryngeal anomalies in newborn infants. Apropos of 687 cases]. 647 14

A 35-year-old man with a brief history of dyspnea and fever experienced rapid progressive respiratory distress and died shortly after being hospitalized. Postmortem examination revealed thrombotic occlusion of the pulmonary tree; the thrombotic material showed Ascaris lumbricoides, Candida albicans, and Mucor. This rare coincidence is an unexpected complication of ascariasis that has not been described previously.
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PMID:Massive thrombosis as a result of triple infestation of the pulmonary arterial circulation by Ascaris, Candida, and Mucor. 647 77

The case is reported of a 26-year-old patient hospitalized after 6 days of coughing and dyspnea with the clinical picture of "adult respiratory distress syndrome" (ARDS). In spite of intensive therapeutic efforts, death ensued within a few weeks. Autopsy revealed widespread intraalveolar metastases of a hitherto unrecognized amelanotic malignant melanoma of the back. Further metastases were only detected in intrathoracic lymph nodes and in the myocardium. A possible relationship between this unusual pattern of metastasis and previous abuse of nicotine, alcohol and hashish, as well as coexisting hypogammaglobulinemia, is discussed. It appears that widespread intrapulmonary metastasis must be considered one of the possible causes of ARDS.
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PMID:[Adult respiratory distress syndrome in extensive intra-alveolar metastasis of an amelanotic malignant melanoma]. 669 64

The radiographic findings of a series of infants of diabetic mothers and a review of the literature are presented to illustrate the wide spectrum of abnormalities that may be seen with this condition. Congenital anomalies of the spine and skeletal, genitourinary, and cardiovascular systems and visceral situs inversus are significantly more frequent among infants of diabetic mothers than normal. The most specific anomaly is sacral agenesis. Renal vein thrombosis and adrenal hemorrhage are also more common and may be diagnosed by sonography. Over one-half of the cases of the small left colon are associated with maternal diabetes and may be diagnosed and treated with a contrast enema. The incidence of the respiratory distress syndrome is higher in infants of diabetic mothers than other premature infants, and the disease may occur in the presence of reliable indicators of lung maturity. Other common causes of dyspnea include cardiomyopathy, congenital heart disease, wet lung syndrome, hyperviscosity syndrome, and persistence of fetal circulation. Echocardiography is the most valuable adjunct in differentiating cardiac from pulmonary problems.
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PMID:Infants of diabetic mothers: radiographic manifestations. 678 62

Four patients with acute nonlymphocytic leukemia and leukocyte counts of more than 200,000/mm3 developed respiratory distress due to pulmonary leukostasis within 10-48 hours after initiation of chemotherapy. Clinically, the patients manifested fever, dyspnea, tachypnea, diffuse pulmonary rales, pleural effusions, and severe hypoxemia. Chest roentgenograms displayed diffuse pulmonary infiltrates, vascular engorgement, cardiomegaly, and pleural effusions. Three patients died from progressive respiratory failure despite ventilatory support. Pulmonary histology revealed thrombi composed of leukemic blast cells which obstructed and distended the lumens of pulmonary arterioles, capillaries, and venules. Electron microscopy studies of lung tissue showed pulmonary alveolar endothelium and basement membrane damage and interstitial edema. The pathophysiologic basis of pulmonary leukostasis and potential treatment modalities are discussed.
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PMID:Respiratory failure due to pulmonary leukostasis following chemotherapy of acute nonlymphocytic leukemia. 683 46

The most common pulmonary disorder induced by methotrexate is a gradually developing interstitial pneumonitis. The associated clinical manifestations include slowly progressive dyspnea and nonproductive cough, with extensive radiographic changes. One case has been reported following intrathecal methotrexate administration; the remainder occurred after either intravenous or oral therapy. We report two cases of rapidly developing respiratory distress following the administration of methotrexate into the cerebrospinal fluid. The clinical courses, radiologic findings, and, in one patient, the pathologic nature, are consistent with noncardiogenic pulmonary edema.
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PMID:Noncardiogenic pulmonary edema following injection of methotrexate into the cerebrospinal fluid. 689 67

We studied the perception of breathlessness as a function of air flow obstruction in 45 asthmatic subjects using a category scaling technique. Air flow obstruction and breathlessness were induced by inhalations of histamine acid phosphate in twofold-increasing concentrations from 0.03 to 16 mg/ml. The FEV1 was measured after each inhalation of histamine, and the subject was asked to rate his symptoms of breathlessness. The results showed that breathlessness increased as the FEV1 decreased but, despite a close linear relationship in all subjects (mean r = 0.88 +/- 0.15 SD), there was a considerable variation in the severity of breathlessness for any particular degree of air flow obstruction (mean intercept, 0.50 +/- 0.89 SD). However, the increase in sensory magnitude with increasing air flow obstruction did not show the same degree of variability (mean slope, 0.13 +/- 0.06 SD). The variability in breathlessness in asthmatic patients is likely to have many components. Two of these components were identified. First, we found that there was less respiratory distress in those subjects in whom air flow obstruction was present at the onset of the study. However, the presence of air flow obstruction at this time does not result in a reduction in sensation for further increases in air flow obstruction as might be expected from discrimination studies. Second, there was a significant relationship (p less than 0.01) between bronchial responsiveness and the magnitude of respiratory distress. Those subjects highly responsive to histamine experienced less respiratory distress than the less responsive subjects.
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PMID:The perception of breathlessness in asthma. 714 47

Varying degrees of respiratory distress developed in 3 dogs in which hyperadrenocorticism was diagnosed. The respiratory distress was attributed to pulmonary artery thrombosis. Radiography revealed pleural effusion, increased diameter and blunting of the pulmonary arteries, lack of perfusion of the obstructed pulmonary vasculature, and overperfusion of the unobstructed pulmonary vasculature. Thrombosis was confirmed by nonselective angiocardiography in each case. In 1 case, selective angiocardiography showed marked reduction of the transit time of contrast medium from the right atrium to the aorta. Hypertension proximal to the site of thrombosis was confirmed in 2 cases by showing increases in the right ventricular systolic pressures (80 mm of Hg in one case and 54 mm of Hg in the other case). In 3 cases, there was moderate hypoxemia with hypocapnia, suggesting a ventilation-perfusion mismatch. Clinical findings other than respiratory distress included hepatomegaly, ventral edema, orthopnea, and a jugular pulse. Pulmonary artery thrombosis, as it occurred in these 3 cases, was compared with the disease in man. It was concluded that pulmonary artery thrombosis should be suspected in cases of intractable dyspnea, right-sided heart failure of unexplained origin, and acute unexplainable death.
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PMID:Pulmonary artery thrombosis in three dogs with hyperadrenocorticism. 723 99

A case of nasopharyngeal teratoma with the appearance of a hairy polyp in one month old infant is presented. The patient had a previous history of recurrent attacks of cough, dyspnea and cyanosis on being fed or in a certain body position (prone). The prone position shifted the tip of the tumor with its long stalk over the entrance of the larynx followed by upper airway obstruction. Prompt surgical extirpation prevented the risk of succeeding fatal respiratory event. This uncommon congenital teratoma arising from the nasopharynx should be taken into consideration in differential diagnosis of neonatal or infantile upper respiratory distress.
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PMID:Nasopharyngeal teratoma.--Report of a case. 744 94


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