Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0476273 (respiratory distress)
 19,632 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Tuberculosis and sarcoidosis are chronic multisystem granulomatous conditions which have different aetiology and management but may mimic each other clinically, radiologically and pathologically. Both these diseases usually have a sub acute or chronic presentation and it is rather uncommon for them to coexist or present with acute respiratory failure. We report a case of a 57-year-old male who presented with pyrexia of unknown origin with chronic cough. He was initially diagnosed to have sarcoidosis based on clinico-radiological and histologic evidence and was started on corticosteroids. However, he presented within two weeks with acute respiratory distress and on further investigation was diagnosed with co-existing pulmonary tuberculosis.
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PMID:Concomitant presentation of sarcoidosis and pulmonary tuberculosis with ARDS: A diagnostic dilemma and therapeutic challenge. 3115 3

Plastic bronchitis is a rare and underdiagnosed disease characterized by the formation and expectoration of bronchial casts of amorphous material, which can be potentially fatal. It is more frequent in pediatric population. Symptoms can range from chronic cough and dyspnea to respiratory failure depending on the area of the compromised airway. Casts are classified as type I when constituted by inflammatory cells and accompany diseases such as asthma and pneumonias; and type II when acellular and are associated with congenital heart diseases following procedures such as Fontan. We report the case of a male schoolchild with a history of complex congenital heart disease, treated with palliative surgery, evaluated in the emergency department for cough and respiratory distress. The mother referred expulsion of gelatinous material after coughing. During clinical evaluation, expulsion of bronchial casts was evidenced, suggesting a plastic bronchitis. He underwent a diagnostic and therapeutic bronchoscopy and received initial treatment with respiratory therapy, nebulized hypertonic saline solution, mucolytics, dornase alpha and nebulized heparin. The hospitalization revealed a stenosis of the right pulmonary artery, which was corrected with stent. The patient progressed satisfactorily with improvement of cough and expectoration. He was discharged with combined treatment, nebulized medications and those concerning his underlying disease.
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PMID:Plastic bronchitis: A case report. 3124 73

Canine bronchomalacia (CBM) is a structural airway disease leading to chronic cough and intermittent respiratory distress, primarily affecting elderly dogs of small breeds. Results of blood gas analysis have been reported in dogs with several diseases, but not yet in those with CBM. Eleven dogs with CBM were recruited in this study. Most dogs presented with mild hypoxemia and normocapnia, and all with increased alveolar-arterial difference for O2 (A-aDO2). In computed tomography, abnormal lung patterns, such as atelectasis and parenchymal band, were detected in all dogs, consistent with the regions affected by CBM. We conclude that CBM causes abnormal lung patterns and results in impaired oxygenation. Blood gas analysis is a useful tool for detecting mild pulmonary lesions and concurrent CBM.
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PMID:Arterial blood gas analysis in dogs with bronchomalacia. 3189 39


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