UMLS:C0476089 - FACTA Search

Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Target Concepts:

Query: UMLS:C0476089 (endometrial cancer)
11,379 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)

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Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein
Sep	687
Mol	562
estrogen receptor	537
p53	481
progesterone receptor	319
PTEN	319
HEC	279
insulin	218
MLH1	204
AKT	181
MSH2	175
aromatase	165
PI3K	156
MSH6	151
nodal	141
mTOR	132
She	132
E-cadherin	116
PMS2	113
Ki-67	88
MRI	85
catenin	84
PIK3CA	82
hormone receptor	82
vascular endothelial growth factor	80
p21	79
cyclin D1	76
caspase-3	74
MAPK	71
Bcl-2	70
erbB-2	70
Pol	69
vimentin	67
p16	66
epidermal growth factor	66
CA125	64
cytokine	61
K-ras	57
BRCA1	57
KRAS	56
hMLH1	56
HER2	55
epidermal growth factor receptor	55
ERK	54
beta-catenin	50
cage	49
POLE	49
p27	48
estrogen receptor alpha	48
phosphatase	47
insulin-like growth factor	47
oestrogen receptor	47
ERK1	46
hMSH2	46
ARID1A	45
androgen receptor	44
LHRH	44
phosphatase and tensin homolog	44
Aromatase	43
BRCA2	40
EGFR	39
proliferating cell nuclear antigen	39
FDG	38
tumour suppressor	38
leptin	37
cancer susceptibility	37
cyclin E	37
Estrogen receptor	37
VEGF	36
histone	36
MMP-9	36
matrix metalloproteinase	35
tyrosine kinase	35
bcl-2	35
cytokeratin	35
kit	34
CD44	34
CTNNB1	33
IGF-I	33
neu	33

Disease
endometrial cancer	11379
cancer	5384
tumor	3150
breast cancer	1421
carcinoma	1410
ovarian cancer	845
adenocarcinoma	764
uterus	694
cervical cancer	612
endometrial hyperplasia	604
obesity	589
metastases	585
carcinogenesis	559
endometrial adenocarcinoma	558
colorectal cancer	387
diabetes	346
tumorigenesis	299
Lynch syndrome	274
hypertension	254
endometriosis	250
osteoporosis	243
epithelial ovarian cancer	232
tumor growth	229
tumor progression	195
infertility	177
polycystic ovary syndrome	163
prostate cancer	150
cardiovascular disease	150
gynecologic cancer	147
uterine cancer	142
colon cancer	126
vagina	121
melanoma	117
adenomyosis	108
lung cancer	100
clear cell carcinoma	97
squamous cell carcinoma	97
uterine cervix	96
polyposis	95
papillary serous carcinoma	94
primary tumor	91
recurrent endometrial cancer	86
carcinosarcoma	86
sarcoma	80
MCF	79
gastric cancer	74
type 2 diabetes	72
hepatocellular carcinoma	72
pelvic inflammatory disease	68
stroke	67
ovarian cysts	66
coronary heart disease	64
leiomyoma	63
renal cell carcinoma	62
endometrial polyp	59
amenorrhea	58
anemia	57
aggressiveness	57
carcinoma of the cervix	56
hyperinsulinemia	54
leukemia	54
myocardial infarction	53
residual disease	52
pancreatic cancer	52
vulvar cancer	52
metabolic syndrome	51
abortion	50
uterine leiomyoma	50
fallopian tube	49
HNPCC	49
uterine sarcoma	47
anovulation	46
cervical adenocarcinoma	45
lymphoma	45
liver cancer	44
Best	44
ectopic pregnancy	44
cervical squamous cell carcinoma	43
liver cancer	43
myoma	42

Symptom
overweight	107
pain	91
menopausal symptoms	78
anesthesia	65
hot flushes	38
hot flashes	38
nausea	33
vomiting	30
abdominal pain	28
discomfort	28
irregular bleeding	26
headache	24
discomfort	23
diarrhea	19
fatigue	19
nausea and vomiting	15
pelvic pain	13
menometrorrhagia	10
weakness	9
arthralgia	9
analgesia	9
starvation	8
dizziness	7
dyspnea	7
constipation	7
anorexia	6
leg cramps	5
insomnia	5
vertigo	5
myalgia	5
night sweats	5
seizures	4
abdominal discomfort	4
cough	4
Ill	4
peri-menopausal	4
thinning	3
intermenstrual pain	3
bloating	3
decreased appetite	3
bone pain	3
colic	3
ataxia	3
erythema	3
hip pain	3
cachexia	3
chills	3
stigma	3
apathy	2
mastalgia	2
low back pain	2
Intermenstrual bleeding	2
leg pain	2
numbness	2
functional recovery	2
Spotting	2
leg edema	2
paresthesia	2
asthenia	2
tonic-clonic seizure	2
back pain	2
hemoptysis	2
masculinization	2
hemiplegia	2
knee pain	2
hypertonia	2
dysuria	2
myoclonus	2
paraparesis	1
muscle stiffness	1
ovulatory bleeding	1
chest pain	1
Lower urinary tract symptoms	1
acute abdomen	1
groin pain	1
reproductive problem	1
McBurney's point	1
inanition	1
bleeding in breast	1
Gastrointestinal symptoms	1

Enzyme
ERK	205
mitogen-activated protein kinase	146
luciferase	118
focal adhesion kinase	66
protein kinase	61
caspase-3	59
reverse transcriptase	37
peroxidase	36
alkaline phosphatase	32
PARP	30
phosphatidylinositol 3-kinase	29
protein kinase C	26
MEK	26
proteasome	26
AMP-activated protein kinase	24
urokinase-type plasminogen activator	23
sulfatase	22
DNA polymerase	21
APC	17
cdc2	17
caspase-8	16
MMP	16
phosphoinositide 3-kinase	16
cathepsin D	16
PRA	15
AMPK	15
AMPK	15
GSK	15
CD10	15
glutathione S-transferase	14
collagenase	13
DNA methyltransferase	13
caspase-9	12
topoisomerase	11
estrogen sulfotransferase	11
calcineurin	11
chloramphenicol acetyltransferase	10
topoisomerase	10
CYP3A4	10
RNA polymerase	10
HSD	10
RNase	9
RNase	9
HDR	9
MAP	9
renin	9
superoxide dismutase	9
aldehyde dehydrogenase	8
BAT	8
aldehyde dehydrogenase	8
aldehyde dehydrogenase	8
aldehyde dehydrogenase	8
trypsin	8
tissue plasminogen activator	8
pyruvate kinase	8
aldehyde dehydrogenase	8
PTPase	8
lactate dehydrogenase	8
17beta-HSD	7
thymidine kinase	7
gamma-glutamyl transpeptidase	7
matrix metalloproteinase 2	7
catalase	7
creatine kinase	6
estrogen sulfotransferase	6
ATPase	6
thymidine phosphorylase	6
thrombin	6
5alpha-reductase	5
endonuclease	5
20alpha-hydroxysteroid dehydrogenase	5
phosphorylase	5
demethylase	5
prostate-specific antigen	5
P-glycoprotein	5
protein phosphatase 2A	5
neuraminidase	5
thymidylate synthase	5
ACS	5
STK11	5