Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
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Drug
Enzyme
Compound
Query: UMLS:C0476089 (
endometrial cancer
)
11,379
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Vulvar lymphedema is an uncommon and disabling side-effect of pelvic lymphadenectomy and pelvic radiotherapeutic treatment for invasive genital cancer.
Lymphorrhea
, a complication of lymphedema, may be extremely distressing for patients due to the requirement to wear sanitary towels and as the pain and loss of elasticity of the vulvar skin and mucosa can cause discomfort during coitus. Surgical treatments of
lymphorrhea
and vulvar lymphedema secondary to gynecological cancer treatments remain controversial and are not currently considered to be the standard therapy. The present study reports two cases of vulvar lymphedema complicated by vulvar
lymphorrhea
in females who had undergone treatment for cervical and
endometrial cancer
, respectively; a review of the literature is also included. In the two present cases, vulvar lymphedemas were refractory to standard treatments, including decongestive therapy, manual lymph drainage, elastic bandaging, low-stretch bandaging, exercises and skin care. Laser CO
2
excision and vaporization of the whole skin and mucosal tissue of the vulva was successfully performed to treat the
lymphorrhea
and improve quality of life. Thus, the present two cases indicated that laser CO
2
surgery may present an additional therapy for the treatment of genital lymphedema that is refractory to other treatments.
...
PMID:Laser CO
2
treatment for vulvar lymphedema secondary to gynecological cancer therapy: A report of two cases and review of the literature. 2578 62
