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Query: UMLS:C0476089 (endometrial cancer)
 11,379 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We have analyzed 37 cases of simultaneous appearance of carcinoma in the ovary and endometrium. This paper deals with the question of whether they should be considered stage III endometrial carcinomas, stage II ovarian carcinomas or independent primary tumors. The cases were grouped according to their histology as endometrioid ovarian carcinomas with endometrial carcinoma (group A), same carcinoma, but not of endometrial origin in both organs (group B) and histologically different concomitant carcinomas of ovary and endometrium (group C). Although our series was small, the survival was better than could have been expected either for stage III endometrial carcinoma, or stage II ovarian carcinoma. This supports the view that many of those tumors should be considered independent stage I carcinomas. Another fact in favour of this hypothesis is the strong correlation between myometrial invasion and prognosis in these cases, which is comparable to that found in endometrial carcinoma alone.
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PMID:Simultaneous appearance of ovarian and endometrial carcinoma: a therapeutic challenge. 272 20

This article presents 19 patients with double primary carcinoma of the uterine corpus and ovary diagnosed and treated at Queen Mary Hospital, University of Hong Kong in last ten years. 14 patients had typical endometrial adenocarcinoma and endometrioid carcinoma of the ovary (group A), 5 had non-endometrioid carcinoma in the uterine corpus and/or ovary (group B). There is no significant difference in survival rate in group A and B (78.6% and 80%, respectively, mean follow-up 42 months), but the total survival rate in our series is 78%, which is equal to stage I ovarian cancer. The tumor grade and positive abdominal washing were proven to be statistically significant indicators of the poor prognosis (P < 0.05). The result reveals that the prognosis of double primary carcinoma of the uterine corpus and ovary is better and it is necessary to distinguish double primary carcinoma of the uterine corpus and ovary from stage II ovarian cancer and stage III endometrial carcinoma.
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PMID:[Double primary carcinoma of the uterine corpus and ovary]. 840 8