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Query: UMLS:C0476089 (endometrial cancer)
 11,379 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This Notice relates to oral contraceptive drug product labeling. It revises the "guideline texts of professional and patient labeling for estrogen-progestogen combination oral contraceptive drug products." This revision is being made to incorporate important new information about the benefits and risks of the use of such products. This information includes "evidence of a decreased incidence of benign breast disorders, functional ovarian cysts and pelvic inflammatory disease, as well as some evidence of protection against the development of ovarian and endometrial cancer. Additionally, oral contraceptive use has been reported to decrease the incidence of iron deficiency anemia and to decrease the incidence of dysmenorrhea".
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PMID:Notice, 13 March 1987. 1234 52

A strategy to establish the diagnosis and the etiology of menorrhagia is necessary for an adaptated therapeutic care. The cross-examination must endeavour to assess bleedings and their clinical impact, and concentrate on specific pathology (such as hemostasis disorders). Clinical examination may eliminate cervical vaginal pathologies and estimate uterine volume. The diagnosis of pregnancy should always be considered and eliminated and that of iron deficiency anemia will be helpful. Explorations of hemostasis balance will be recommended according to clinical and biological features. Hormonal measurement are not contributive, except in diagnosis of SOPK. Endometrium biopsy with the Pipelle will be systematically performed after 40 years of age or in case of risk factors of endometrial cancer. Transvaginal ultrasonography is the first line exam to recommend in case of proved menorrhagia. Hysteroscopy and hysterosonography will be recommended if ultrasonography is not informative enough, or in case of medical treatment failure. MRI is recommended in an second intention (in case of multiple uterine fibroids, or suspected adenomyosis, and if an arterial embolization is required).
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PMID:[Hierarchy for diagnostic and etiological management in menometrorrhagia]. 1926 13

Wireless capsule endoscopy (CE) was introduced for human clinical diagnostic utilization in 2001. CE has become a first line method of evaluating the small intestine for suspected abnormalities and disease. Contraindications to CE include the presence of intestinal obstruction, fistulas, or structures. Capsule retention has been reported in patients with a strictured or stenotic area of intestine caused by occult neoplasm, nonsteroidal anti-inflammatory drugs, Crohn's disease, radiation enteritis, or previous abdominal surgery. Safe and effective use of CE has been reported in the evaluation of patients who have previously undergone surgical resection of the small intestine for benign or malignant disease. This case report reviews the utilization and subsequent retention of an endoscopic capsule in a symptomatic patient who had a previous small bowel resection caused by the sequelae of radiation therapy to the abdomen and pelvis for endometrial cancer. The retained endoscopic capsule required surgical removal after the patient developed an iron deficiency anemia. The resected segment of small intestine contained the endoscopic capsule, previous intestinal anastomosis, recurrent bowel strictures secondary to radiation enteritis, and a chronic ulcerated intestinal lumen caused by the retained endoscopic capsule. This case report shows that use of CE cannot always be considered safe in patients who have had a previous surgical intestinal anastomosis. CE should not be used in patients who have had a previous small bowel resection and anastomosis for symptomatic intestinal structures that developed because of radiation enteritis.
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PMID:Endoscopic capsule retention in an intestinal anastomosis. 2018 21


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