Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0451641 (urolithiasis)
 3,973 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The serum vitamin A level of the lithiasis patients was found to be low, although vitamin A intake was not different from control subjects. Vitamin C level in blood was not significantly different in the patients as compared with control subjects. The control subjects and urolithiasis patients were also subjected to the oral supplementation of L-tryptophan and glycine. It was observed that neither oxalate nor xanthurenic acid increased in urine after loading. It was concluded that vitamin B6 deficiency does not exist in these cases.
 ...
PMID:Role of vitamins in urolithiasis. 307 83

In 90 patients with calcium oxalate urolithiasis an oral tryptophan-loading test with 5 g L-tryptophan was performed and the 24-hour urinary excretion of xanthurenic acid and kynurenine was measured. In 10 cases pathological deviations and an excretion pattern of tryptophan metabolites via kynurenine similar as in the hereditary vitamin-B6-dependent xanthurenic aciduria in homozygous or heterozygous from were found. Correlations between the oxalate excretion and the tryptophan metabolism do not exist. A 2-year therapy with 60 mg vitamin B6 was favourable in patients with an excretion of more than 300 mumol XA after a tryptophan load.
 ...
PMID:[Studies on tryptophan metabolism in calcium oxalate urolithiasis]. 340 38