Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0451641 (urolithiasis)
 3,973 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

On 27 January 2000, a struvite calculus was observed in the vagina during necropsy of a 138-cm-long female bottlenose dolphin (Tursiops truncatus) collected from the Stono River, South Carolina (USA). Vaginal calculi have been reported in other species of cetaceans but not in bottlenose dolphins. Urinary tract infection might have been an underlying cause of the calculus. While urinary tract inflammation was not detected by light microscopic evaluation of sections of the urinary tract, it is conceivable that sufficient time had lapsed following voiding of the calculus through the urethra for urinary tract infection to have resolved. To further define the prevalence and significance of urolithiasis, prosectors of dead stranded marine mammals are encouraged to closely observe their urinary and genital tracts for calculi and to submit them for quantitative analysis.
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PMID:Struvite calculus in the vagina of a bottlenose dolphin (Tursiops truncatus). 1513 99

Urinary tract infections belong among the most common infectious diseases in adult women. Sporadic infection is usually not a diagnostic and therapeutic problem. Recurrent lower urinary tract infections significantly decrease the quality of life of the affected women. Colonisation of the vagina, vulva and the perineum by the uropathogens is the main risk factor of any urinary infection, but only concomitant action of some other factor (e.g. immunosuppression, urethral stenosis, urolithiasis, urethral diverticulum, diabetes and urinary incontinence) can induce the recurrent infection. Correct primary treatment and proper used preventive method is highly advantageous not only from the individual but also from the global point of view (high diagnostic and therapeutic expenses, increase of resistance and imminent success decrease of the modern treatment). Continuous low dose antimicrobial treatment is the most common prophylactic modality. Postcoital antimicrobial prophylaxis and immunomodulative therapy are the other used modalities. Local vaginal estrogen therapy is recommended in postmenopausal women. Estrogens improve the symptoms of the urogenital atrophy and decrease the vaginal pH, which is very important in prevention of the pathological bacterial colonisation of the vagina. Decision about the individual therapy and prophylaxis must be preceded by the evaluation of the risk factors with positives and negatives of the used drug.
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PMID:[Lower urinary tract infections in urogynaecology]. 1594 85