Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0451641 (urolithiasis)
 3,973 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Ceftizoxime (CZX), a parenteral cephalosporin derivative belonging to the so-called third generation cephalosporin is reported to have a broad antibacterial activity, particularly against Gram-negative aerobic bacilli and some anaerobes, such as Bacteroides fragilis and a good stability to beta-lactamases. Clinical study was performed on a total of 20 cases, 9 females (1 case had urinary tract infection 3 times) and 11 males, aged from 27 to 82 years. All patients had the underlying diseases. They were bronchial asthma in 3 cases, influenza in 1, chronic pulmonary emphysema in 1, pulmonary fibrosis in 1, chronic bronchitis with strongyloidiasis in 1, lung cancer in 3, esophagus cancer in 2, stomach cancer in 1, hepatoma with urolithiasis in 1, liver cirrhosis with diabetes mellitus in 1, alcoholism with strongyloidiasis in 1, cholelithiasis in 1 and congestive heart failure in 1, respectively. Clinical diagnoses for infections were 2-acute bronchitis, 2-exacerbation of chronic bronchitis, 2-broncho-pneumonia, 2-pneumonia including one suspected case, 1-obstructive pneumonia, 2-secondary pulmonary infection, 1-pulmonary infection, 3-urinary tract infection (UTI), 1-UTI with sepsis, 1-sepsis, 1-sepsis with purulent meningitis, 1-biliary tract infection and 1-infected bronchoesophageal fistula. CZX was given by intravenous drip infusion, at a dose of 1 to 2 g, twice daily for 3 to 15 days. Because of severity in infections and underlying diseases, some cases were treated either steroid, gamma-globulin preparations or other antibiotics in combination with CZX. Twelve out of 15 cases assessed clinically responded satisfactorily to the treatment and efficacy rate was 80.0%.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[Effectiveness of ceftizoxime on various infections in patients with underlying diseases]. 609 Jul 23

In the United States Navy, many diagnoses are considered disqualifying for aviation duty, but aircrew may be "waived" to return to flight duties after resolution of the disease or appropriate treatment of the condition. Personnel with waivers are usually subject to more frequent physical examinations and/or special diagnostic procedures. Although the Naval Aerospace and Operational Medical Institute promulgates written aeromedical guidelines as to which diseases may be waived and which may not, waivers are granted on a case-by-case basis considering not only the diagnosis, but the age, experience, and type of aviation duty of the individual in question. This study was undertaken to determine which conditions were most and least likely to be waived. We reviewed all records of aviators entered into the Naval Aviation Medical Data Retrieval System who had been diagnosed with a condition considered disqualifying for aviation duty, totaling over 39,000 records. Cases were stratified by diagnosis and aviation duty, and the percentage waived was calculated for major diagnostic groups. Among designated aviation personnel, approximately 68% of all aviators with a disqualifying diagnosis were recommended for a waiver. Otolaryngologic, musculoskeletal, and cardiovascular disorders accounted for nearly 50% of diagnoses in personnel recommended for a waiver. Fear of flying, personality disorders, and adjustment disorders were the three diagnoses least likely to be granted a waiver. The most frequently occurring disqualifying diagnoses were allergic rhinitis, obesity, disorders of refraction and accommodation, urolithiasis, and alcohol dependence.
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PMID:Waivers for disqualifying medical conditions in U.S. Naval aviation personnel. 761 31