Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0432222 (SEM)
 47,337 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Transmission and scanning electron microscopic studies were made of regeneration of the vascular network of rat tracheal mucosa on 30 min to 8 hr after the mechanical curettage. The vascular network casts were made by infusion of Mercox resin through the aortic arch for scanning electron microscopy. At 30 min after curettage, vascular thromboses were observed, and terminal blind branches were formed in the injured blood vessels areas through SEM observation. Diapedesis of leukocytes appeared at 30 min after curettage from intact venules at the wound margins. Recovery from the loss of endothelial cells began at 30 min after curettage. At 3 hr after curettage, vascular indentation (protrusion) and vascular process (bud-like process) were developed from intact venules at the wound margins. It is concluded that the formation of thrombus and terminal blind branch vessels constitute the initial reparative reactions of the injured vascular network and that new vessels then begin to form by outgrowth of protrusions and bud-like processes from intact venules at the wound margins.
Auris Nasus Larynx 1992
PMID:Electron microscopic study of vascular regeneration in rat tracheal mucosa following physical curettage. 129 99

Nasal administration of drugs is an administration method which is worthy of attention. In such therapy, local administration should not damage the nasal mucous membranes. In the present study, we conducted an investigation by the tissue culture test method of the functional and morphological effects of new nasal calcitonin preparation, which is being developed as a nasal spray agent for osteoporosis, on the nasal ciliary epithelium. The nasal septal mucous membranes of C3H-strain mice were used, and 5 types of nasal calcitonin preparations with a microcrystalline cellulose base and additives added were used. The various drugs were added to nasal mucous membrane slices in RPMI-1640 culture medium; ciliary activity before addition and 0.5, 2, and 4 hr after was electrophotometrically measured; and morphological observation was then carried out by SEM. In the various additive groups, virtually no effect on ciliary activity was observed, and the same results were obtained when 3 and 9 times the estimated clinical spray dosage was added. Moreover, in morphological observation by SEM, in the various additive groups, no morphological changes in samples of nasal ciliary specimens were observed after 4 hr of culturing at the maximum administered dosage (9 times the estimated clinical spray dosage). Based on these findings, it was concluded that the series of calcitonin preparations with various additives had no hazardous effect on the nasal ciliary epithelium.
Auris Nasus Larynx 1992
PMID:Basic study on the effect of nasally administered salmon calcitonin preparation on the nasal ciliary epithelium. 141 74

NaOH cell-maceration/SEM method was applied to the oral surface of the mouse palate to demonstrate the three-dimensional architecture of the lamina propria. In the caudal part of the hard palate, the lamina propria was characterized by the conspicuous parallel ridges which ran side by side in sagittal direction. In the boundary between the hard palate and the soft palate the parallel ridges interrupted abruptly, in the soft palate the ridges were extremely undeveloped to show the shrunken cloth-like appearance. Furthermore, the conical connective tissue papillae were lined up along the boundary. These findings suggest that the boundary between the hard plate and the soft palate is clear not only in the bony structure but in the lamina propria, and that the parallel ridges in the hard palate play an important role in ensuring from the excessive extending force during mastication.
Auris Nasus Larynx 1992
PMID:NaOH cell maceration/scanning electron microscopic studies on the architecture of the lamina propria of the mouse palate. 141 75

In the lateral wall of the laryngeal ventricle of the Suncus murinus, only a few excretory ducts of the laryngeal gland opened that drained the extensive lobular system. The ducts opened into the "intermediate epithelium (NAKANO, T.: Acta Anat. 127: 22-47, 1986)," which lined the transitional zone between the ciliated columnar epithelium and the stratified squamous one, and that showed gradations ranging from the ciliated stratified low-columnar through stratified cuboidal to stratified squamous type. The orifice of the laryngeal gland was relatively wide for the size of the animal and, therefore, the epithelium within the orifice was clearly observed by use of SEM. As the number of the ciliated cells decreased in the intermediate epithelium surrounding the orifice, the ciliated cells within the orifice reduced in number. Considering from these findings, it is suggested that the epithelium within the orifice has morphologically close resemblance to, and is influenced by, the epithelium surrounding the orifice.
Auris Nasus Larynx 1990
PMID:The epithelium lining the orifice of the laryngeal gland of the Suncus murinus, with special reference to the "intermediate epithelium (Nakano)". 227 28

Morphogenetic studies of the esophageal mucosa in human fetuses have been few and there is only one report at the ultrastructural level. We thus studied the esophageal mucosa in human fetuses (at the gestational ages from the 7th to 21st week) by scanning (SEM) as well as transmission electron microscopy (TEM). Our results and the review of the literature lead to the following conclusions: 1) Primary cilia were seen in the 7th and 8th week of gestation. 2) Ciliated cells appeared around the 8th week of gestation. They increased in number according to the fetal ages, but gradually decreased after the 14th week of gestation. Their degenerative process at the ultrastructural level was similar to that reported previously. 3) The stratified squamous epithelia appeared at the 14th week of gestation, but the squamous cells remained immature even at the 21st week. 4) Glycogen granules in non-ciliated cells decreased as the differentiation of the cells proceeded, suggesting that they provide an energy source necessary for the cell differentiation.
Auris Nasus Larynx 1989
PMID:Electron microscopic study on the esophageal mucosa in human fetuses. 261 35

The differentiation of the epiglottic mucosa in human fetuses has so far been studied only by light microscopy. So, we studied the epiglottic mucosa in human fetuses (at gestational ages from the 7th to 21st week) by scanning (SEM) and transmission electron microscopies (TEM), and could disclose more detailed features of cellular differentiation of this mucosa. These results and the review of the literatures lead to the following conclusions: 1. Primary cilia appeared in the epiglottic mucosa around the 7th week of gestation. 2. Ciliated cells and the stratified squamous epithelium of the lingual surface appeared at the similar period as reported by others, but our study revealed that the squamous cells are immature even at the 21st week. 3. Glycogen granules in non-ciliated cells decreased paralleling the differentiation of the cells, suggesting that they provide a source of energy necessary for the cell differentiation.
Auris Nasus Larynx 1987
PMID:Electron microscopic study on the epiglottic mucosa in human fetuses. 345 36