Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0426980 (motor symptom)
 471 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
SYNGR4 16.0
PLEKHB1 13.2
DPYSL2 10.8
PDE1B 10.4
LPD 10.3
SOX-10 10.2
AIFM1 10.2
REP1 9.9
HCN3 9.9
OMD 9.8
STN 9.6
DBS 9.4
ddc 9.3
PPX 9.0
with Parkinsonism 9.0
ATP1A3 8.9
PRG 8.8
ATP1A2 8.8
LCE 8.6
PDE4A 8.5
Dopamine transporter 8.5
GluR-A 8.4
G protein-coupled estrogen receptor 1 8.4
leucine-rich repeat kinase 2 8.3
MDS 8.2
ubiquitin C-terminal hydrolase 8.2
CMAP 8.2
SNCA 8.2
alpha-synuclein 7.9
mitogen-activated protein kinase kinase kinase 7.9
HTT 7.8
LRRK2 7.7
TARDBP 7.7
SLC2A1 7.7
MuSK 7.7
IDS 7.6
TH protein 7.5
AMR 7.5
synuclein 7.5
CACNA1A 7.4
G15 7.4
ADAS 7.4
MSA 7.3
DJ-1 7.3
GDS 7.3
H-Y 7.3
MTR 7.2
CIT 7.2
PSEN1 7.2
CTRL 7.1
GLT-1 6.8
Phosphodiesterase 6.8
SCN1A 6.8
5-HT2B 6.8
dopamine transporter 6.7
huntingtin 6.7
superoxide dismutase 1 6.7
PINK1 6.7
Arnt 6.7
parkin 6.7
P200 6.6
ChAT 6.6
CDT 6.6
PCS 6.5
DAT 6.5
Dance 6.5
PDC 6.4
retino 6.4
PND 6.4
Huntingtin 6.4
neurogranin 6.4
catechol-O-methyltransferase 6.3
TDP-43 6.2
AChR 6.2
GAF 6.2
insulin-like growth factor II 6.1
BIS 6.1
vesicular monoamine transporter 2 6.1
dopa decarboxylase 6.0
GDNF 6.0
more...
Disease
Motor Disorders 13.2
Hypokinetic dysarthria 13.0
Orofacial dyskinesia 12.3
Bowel dysfunction 11.0
Speech impairment 10.7
taste disorder 9.7
Corticobasal degeneration 9.3
REM sleep behavior disorder 9.2
FFS 9.0
impulse control disorder 8.8
gastrointestinal dysfunction 8.8
Stereotypy 8.7
behavior disorder 8.7
hemiparkinsonism 8.6
Parkinson's disease 8.6
reflex epilepsy 8.6
hemiplegic migraine 8.5
Sleep disturbance 8.4
Multiple system atrophy 8.3
Chronic inflammatory demyelinating polyradiculoneuropathy 8.2
sirenomelia 8.2
MDS 8.1
neuromyotonia 8.1
movement disorder 8.1
cognitive disorder 8.0
SAPHO syndrome 8.0
dyskinesia 7.9
tarsal tunnel syndrome 7.9
parasomnia 7.6
hysteria 7.6
Huntington's disease 7.5
Essential tremor 7.4
speech disorder 7.3
CDT 7.3
MSA 7.3
parkinsonism 7.2
dysautonomia 7.2
CES 7.2
BPS 7.1
Li-Fraumeni syndrome 7.1
incontinentia pigmenti 7.0
sleep disturbances 6.8
restless legs syndrome 6.7
abnormal involuntary movements 6.7
Frey 6.7
Dystonia 6.6
sleep disorders 6.6
PCS 6.5
dysphasia 6.5
akinesia 6.5
Spinocerebellar ataxia 6.4
multiple disorders 6.4
PDC 6.4
DWI 6.4
Dementia with Lewy bodies 6.4
PND 6.3
polyradiculoneuropathy 6.3
Guillain-Barre syndrome 6.3
nerve entrapment 6.3
osteosclerosis 6.3
alopecia areata 6.2
hallucinations 6.2
trichotillomania 6.1
self-injurious behavior 6.1
intellectual impairment 6.1
endometrial stromal sarcoma 6.0
conversion reaction 6.0
mutism 5.9
progressive supranuclear palsy 5.9
stereotypies 5.9
ICC 5.9
nerve lesion 5.8
ICC 5.8
cognitive impairment 5.8
nocturia 5.8
seborrheic dermatitis 5.7
brain dysfunction 5.6
PDD 5.6
degenerative disease 5.6
motor neuron disease 5.5
more...
Symptom
motor symptom 16.0
dribbling saliva 15.0
Dellen 13.5
Swallowing problems 10.5
bradykinesia 10.4
Visual symptoms 9.2
chorea 8.5
Involuntary Movement 8.4
visual hallucination 7.9
mental fatigue 7.9
tremor 7.7
drooling 7.7
apathy 7.6
eds 7.6
muscle rigidity 7.6
catatonia 7.5
blepharospasm 7.0
abnormal gait 6.9
dystonia 6.8
Fluctuation 6.8
limb pain 6.7
forgetfulness 6.6
constipation 6.6
Depressive symptoms 6.1
sleepiness 6.0
dysarthria 5.8
myoclonus 5.6
anosmia 5.5
photophobia 5.4
bloating 5.3
alexithymia 5.3
cerebellar ataxia 5.2
neck pain 5.1
spasticity 5.0
paresthesia 4.8
fatigue 4.6
insomnia 4.3
hemiplegia 4.1
weakness 4.0
cachexia 3.6
hypotonia 3.5
pain 3.4
spasm 3.2
nausea 3.1
ataxia 3.1
dizziness 2.8
thinning 2.6
stigma 2.3
seizures 2.3
chest pain 2.0
headache 1.9
analgesia 1.3
Drug
Permax 13.2
Permax 13.2
Fluvoxamine maleate 12.2
Fluvoxamine maleate 11.5
Rotigotine 10.4
Rasagiline 9.8
Carbidopa 9.7
DBS 9.4
Pramipexole 9.4
Pramipexole 9.3
Tapentadol 9.2
Vardenafil 8.6
MDS 8.2
Sinemet 8.0
Duloxetine 7.8
Domperidone 6.6
Gabapentin 6.2
Oxaliplatin 6.2
TMS 5.9
9-THC 5.3
Amiloride 5.2
TTC 5.2
Spectrum 5.1
Frontal 5.0
Spectrum 4.0
Posture 3.6
ROC 3.1
CSF 2.1
caffeine 1.6
Enzyme
phosphatidylinositol-4,5-bisphosphate 3-kinase 8.4
DOPA decarboxylase 7.0
isopeptidase 6.9
DAT 6.5
Pla 6.2
botulinum neurotoxin 6.2
BIS 6.1
tyrosine aminotransferase 5.7
MEKK1 5.2
MPP 5.2
MDP 4.7
tyrosine hydroxylase 4.2
monoamine oxidase 3.7
complex I 2.9
phosphodiesterase 2.8
acetylcholinesterase 2.8
cholinesterase 2.4
caspase-3 0.9
catalase 0.3
ACS -0.2
protein kinase -0.3
ERK -0.5
mitogen-activated protein kinase -0.5
Compound
Carbidopa-levodopa 13.0
S 10 10.8
Meclizine 10.5
PDQ 10.1
DBS 9.4
1,2,3,6-tetrahydropyridine 9.2
1,2,3,6-tetrahydropyridine 9.2
Tetrabenazine 9.2
Edaravone 7.7
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 7.6
MPTP 7.5
CDT 7.3
CES 7.2
Crocin 7.2
L-DOPA 7.1
MEGA 6.8
R 2 6.5
DAT 6.5
Rotenone 6.4
AEA 6.4
Yohimbine 6.1
Valproic acid 6.0
AEA 5.7
CIT 5.6
CIT 5.6
Amide 5.5
MPP 5.3
Dopa 5.3
MPP 5.2
Stimul 5.1
Dopamine 4.9
TTC 4.9
Neo 4.4
Valproic acid 4.3
EDS 4.3
Histone 3.8
Morphine 3.7
PAS 3.4
noradrenaline 3.4
Vitamin D 3.3
Off 3.3
Neurotol 3.2
gamma-aminobutyric acid 3.1
5-HT 3.1
DSM 2.9
GMP 2.9
isopropanol 2.8
CAT 2.8
aspartic acid 2.4
uridine 2.4
pyrimidine 1.8
pyrimidine 1.7
cGMP 1.7
caffeine 1.6
SDS 1.3
vitamin D 1.3
proline 1.1
nitric oxide 1.0
GABA 1.0
manganese 1.0
GABA 0.9
glutamate 0.9
acetate 0.8
glycerol 0.7
potassium 0.5
Dec 0.2
Clin 0.1
iron -0.0
alanine -0.1
galactose -0.1
glucose -0.2
ACS -0.2
ACS -0.2
sodium -0.5
copper -0.5
tyrosine -0.5
calcium -0.7
sulfate -0.7
salt -0.8
ATP -1.0
more...