Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0424790 (rigors)
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Human Gene/Protein
Myokinase 12.7
IFN-R 11.3
cardiac myosin binding protein-C 10.3
Gemin5 10.0
cardiac MyBP-C 9.5
LFA3 9.5
adenosine monophosphate deaminase 9.3
GTB 8.8
tropomyosin isoform 8.8
UTE 8.5
IFN-alpha 2 8.2
GPR109A 7.9
FOP 7.8
CEACAM6 7.7
EPAS1 7.5
tetranectin 7.2
HLA Class I 7.2
RSS 7.1
DMB 7.1
2',5'-oligoadenylate synthetase 7.1
KAP 7.0
alpha-galactosidase 7.0
beta-spectrin 6.9
CD52 6.8
alpha-tropomyosin 6.7
myosin V 6.7
Zap 6.7
CD16) 6.7
PGK1 6.6
Interleukin-15 6.4
beta-2 microglobulin 6.4
lipopolysaccharide-binding protein 6.4
PHD2 6.4
I-1 6.3
Indoleamine 2,3-dioxygenase 6.3
CSI 6.3
erg 6.3
alpha-spectrin 6.3
STE 6.3
NALP3 6.2
interleukin-1 receptor antagonist 6.2
MTD 6.2
CD33 6.1
BSN 6.1
decay-accelerating factor 6.1
alpha-galactosidase A 6.0
Interleukin 2 5.9
MTP 5.9
IL-2 receptor 5.9
SON 5.9
troponin C 5.8
white cell 5.8
breakpoint cluster region 5.8
Was 5.8
PPT 5.8
OPD 5.7
beta-2-microglobulin 5.7
GLA 5.7
interleukin-2 5.6
H10 5.5
CCNU 5.4
PFP 5.4
ELF 5.4
Fc gamma 5.3
TNF-a 5.3
PNP 5.3
p24 antigen 5.2
MCT 5.2
trip 5.2
ARB 5.2
LAK 5.2
ape 5.2
E1B 5.2
interleukin 2 receptor 5.1
ARS 5.1
B23 5.1
apyrase 5.0
IL-1 alpha 5.0
calpastatin 5.0
NHE1 5.0
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Disease
Louse-borne relapsing fever 13.4
Necrobacillosis 12.4
localized skin infection 12.1
Haverhill fever 11.4
Leiner 11.3
Human ehrlichiosis 11.1
rat-bite fever 11.0
crystal arthropathy 10.8
Staphylococcus epidermidis infection 10.4
P.ovale 10.4
systemic blastomycosis 10.4
MSSE 10.3
Impetigo herpetiformis 10.2
Chikungunya virus infection 9.8
vasitis 9.7
Acute cholangitis 9.3
Ureter 9.3
Ureter 9.3
Waterhouse-Friderichsen syndrome 9.2
Harley 9.1
NML 9.0
Generalized pustular psoriasis 9.0
Anaplasmosis 8.9
Generalized pustular psoriasis 8.8
Ecthyma gangrenosum 8.8
Azotemia 8.8
Choledochal cyst 8.8
Miliary tuberculosis 8.7
compulsive personality 8.6
adenocarcinoma of unknown primary 8.4
DRESS syndrome 8.4
Transfusion-related acute lung injury 8.3
diabetic ulcer 8.3
Plasmodium vivax malaria 8.2
Staphylococcus aureus endocarditis 8.2
Prostatitis 8.1
Lemierre's syndrome 8.0
Central diabetes insipidus 8.0
Aeromonas hydrophila infection 7.9
Disseminated histoplasmosis 7.9
AIDS-related Kaposi's sarcoma 7.9
ecthyma 7.8
acute osteomyelitis 7.8
Ogilvie's syndrome 7.7
RAEB-T 7.7
Gram-negative bacteremia 7.6
acute tonsillitis 7.6
penicillin allergy 7.6
pharyngotonsillitis 7.6
T-cell prolymphocytic leukemia 7.6
fibrocystic breast disease 7.5
chigger 7.5
Invasive pulmonary aspergillosis 7.4
infectious arthritis 7.4
Tolosa-Hunt syndrome 7.3
Muckle-Wells syndrome 7.3
Tension 7.3
amebic colitis 7.3
sexual offense 7.2
asthmatic bronchitis 7.2
relapsing fever 7.2
meningococcal infection 7.2
Adult-onset Still's disease 7.1
RSS 7.1
evaluable disease 7.1
petechiae 7.0
balanitis 7.0
bronchospasm 6.9
Blastomycosis 6.9
metastatic renal cell carcinoma 6.9
recurrent prostate cancer 6.9
body lice 6.8
human granulocytic ehrlichiosis 6.8
localized infection 6.8
meningococcemia 6.8
endarteritis 6.7
Bielschowsky 6.7
impaired driving 6.7
fungemia 6.7
Sutton 6.7
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Symptom
rigors 15.2
muscle rigidity 11.8
Chronic pelvic pain syndrome 10.4
Murphy's sign 10.3
chills 10.2
Vaginal dryness 10.1
Flu-like symptoms 9.4
dark urine 8.1
frequent urination 7.8
testicular pain 7.8
generalized pain 7.6
myalgia 7.5
pedal edema 7.5
right upper quadrant pain 7.4
sore throat 7.4
night sweats 7.3
body pain 7.2
pleuritic chest pain 7.0
urethral discharge 7.0
elbow pain 7.0
rales 6.9
nausea 6.9
meningism 6.8
flank pain 6.7
prostration 6.7
Tenderness 6.7
productive cough 6.7
groin pain 6.7
chest tightness 6.7
Ill 6.5
orthopnea 6.4
vomiting 6.4
Catch 6.2
abdominal cramps 6.2
ankle pain 6.2
hepatosplenomegaly 6.1
anorexia 6.1
nasal congestion 6.1
abdominal discomfort 6.1
arthralgia 6.0
muscle stiffness 6.0
oliguria 6.0
drooling 5.9
headache 5.7
clonus 5.7
cyanosis 5.7
hepatomegaly 5.5
lethargy 5.4
Stiffness 5.3
microbial colonization 5.2
eds 5.2
urinary frequency 5.1
hypoproteinemia 5.1
epigastric pain 5.1
decreased appetite 5.0
dysuria 5.0
abdominal pain 5.0
fatigue 4.9
shortness of breath 4.9
neck pain 4.9
tonic-clonic seizure 4.9
back pain 4.8
nausea and vomiting 4.8
dyspnea 4.8
cough 4.8
anosmia 4.7
bone pain 4.6
sciatica 4.6
photophobia 4.6
flushing 4.6
diarrhea 4.6
despair 4.6
torticollis 4.6
erythema 4.6
splenomegaly 4.6
bloating 4.5
dizziness 4.3
fever of unknown origin 4.2
stridor 4.1
chest pain 4.0
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Drug
Mifamurtide 11.9
Muromonab-CD3 11.7
Agalsidase alfa 11.2
Compazine 10.7
Cevimeline 10.6
Ambisome 10.4
Fabrazyme 10.3
Lomotil 10.0
Lomotil 10.0
Mercaptopurine 9.9
Orthoclone OKT3 9.7
Aredia 9.6
AmBisome 9.6
Azacytidine 8.7
Neocarzinostatin 8.5
anti-CD33 8.4
Campath 8.3
Campath 8.3
Omniscan 8.1
Gastro 8.0
Panitumumab 7.9
Mesalazine 7.4
Dextrose 6.6
CSI 6.4
Oseltamivir 6.0
Urokinase 6.0
Trib 5.8
APD 5.4
Methylprednisolone 5.4
Oxaliplatin 5.4
Rituximab 5.3
IFN-beta 5.3
Clopidogrel 5.1
DPA 4.9
Tacrolimus 4.5
TTC 4.4
Itraconazole 4.3
Frontal 4.2
Portal 4.2
uPA 4.2
HCG 3.9
Fluorescein 3.8
Alanine 3.8
Ringer's solution 3.8
CAM 3.7
MRC 3.5
Fluorescein 3.4
niacin 3.4
CTX 2.9
Bifidobacterium 2.7
caffeine 2.4
IFN-gamma 2.4
CSF 2.3
EE2 2.3
ENT 2.2
nitroglycerin 2.1
IL-2 2.0
Gel 1.4
Dial 1.3
lactose 1.2
ampicillin 1.2
Leaf 0.8
Monit 0.1
Dermatol -0.4
lysine -0.6
Cardiovasc -0.8
Enzyme
PHT 7.3
myosin ATPase 6.7
MTD 6.0
AMP deaminase 5.8
indoleamine 2,3-dioxygenase 4.8
apyrase 4.7
alpha-galactosidase 4.5
AOR 4.5
adenylate kinase 4.3
sialidase 3.8
tryptase 3.8
ricin 3.6
granzyme B 3.6
aspartate aminotransferase 3.2
glyceraldehyde-3-phosphate dehydrogenase 3.2
glyceraldehyde-3-phosphate dehydrogenase 3.1
glyceraldehyde-3-phosphate dehydrogenase 3.0
DNA methyltransferase 3.0
pyruvate kinase 2.9
glyceraldehyde-3-phosphate dehydrogenase 2.8
tissue plasminogen activator 2.8
AST 2.7
creatine kinase 2.6
glyceraldehyde-3-phosphate dehydrogenase 2.6
aldehyde dehydrogenase 2.6
alanine aminotransferase 2.5
prostate-specific antigen 2.5
urease 2.4
urease 2.4
alkaline phosphatase 2.3
xanthine oxidase 2.2
gamma-glutamyl transpeptidase 2.1
elastase 2.1
collagenase 2.1
lipase 2.1
urokinase-type plasminogen activator 1.9
ATPase 1.8
acid phosphatase 1.6
neuraminidase 1.4
calcineurin 1.2
phospholipase C 1.1
focal adhesion kinase 0.8
protein kinase C 0.7
reverse transcriptase 0.3
thrombin 0.2
trypsin -0.1
ERK -0.3
catalase -0.5
ACS -1.0
Compound
Gadodiamide 9.2
Salina 8.8
Neocarzinostatin 8.5
Sulfatide 8.2
Amphotericin B 7.6
PHT 7.3
DMB 7.1
Cefotaxime 7.0
Meperidine 6.8
5-FC 6.8
DMB 6.8
Neostigmine 6.7
6-Mercaptopurine 6.6
Oseltamivir 6.6
Teicoplanin 6.6
5-Azacytidine 6.5
Sulfasalazine 6.4
Rifampicin 6.2
Quinine 6.1
Match 5.9
Mannitol 5.9
Mannitol 5.8
Interleukin-2 5.7
Uridine 5.6
Methylprednisolone 5.5
Dexmedetomidine 5.5
Tumor Necrosis Factor 5.5
CCNU 5.4
Chloroquine 5.4
Chloroquine 5.4
Isoflurane 5.3
PPi 5.3
Azathioprine 5.2
Diclofenac 5.2
DPA 5.2
DPA 5.1
Vancomycin 5.0
DPA 5.0
Ribavirin 5.0
DPA 5.0
DPA 4.9
DPA 4.8
DPA 4.7
DPA 4.7
DPA 4.7
DPA 4.7
DPA 4.7
DPA 4.7
CPA 4.7
Tetracycline 4.6
phosphocreatine 4.5
CPA 4.5
CPA 4.5
Phorbol 4.2
CPA 4.2
neopterin 4.2
Estate 4.2
Wellcome 4.2
PPI 4.2
PNP 4.2
Fibrin 4.1
TTC 4.1
GPT 4.0
Starch 3.9
DIC 3.9
Alanine 3.9
LTC4 3.8
creatinine 3.7
CTAB 3.7
Valproic acid 3.5
6-12 3.4
acridine 3.4
His 3.4
THE 3.3
nicotinic acid 3.2
chromate 3.1
GAL 3.0
Triton X-100 2.9
CTX 2.9
Morphine 2.9
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