Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0423716 (Neuropathic pain)
1,417 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ZSCAN20 13.5
palmitoyl-protein thioesterase-2 13.5
SLC24A2 12.5
Kv9.1 11.6
transmembrane protein 97 11.5
ZNF609 11.5
KCNMB3 11.3
pim-1 protein 10.9
SNX8 10.9
PAP-I 10.2
TMEM97 10.1
Meteorin 9.6
SPHK 9.6
RAP1A 9.5
PCP2 9.5
transmembrane protein 3 9.5
RPL29 9.5
TMEM119 9.4
RPL3 9.4
Nav1.3 9.4
MT5-MMP 9.4
KCNA2 9.2
SNL 9.2
RPL19 9.2
jagged 1 9.2
HDAC2 protein 9.2
ribosomal S6 protein kinase 9.1
myeloid zinc finger 9.1
citrate transport protein 9.0
histone-lysine N-methyltransferase 8.9
HDAC1 protein 8.9
HLA-A*33 8.9
LNP 8.9
UBP43 8.9
P2X4 8.8
SCN3A 8.8
VRL-1 8.8
P2X4R 8.8
KNG1 8.8
LPCAT2 8.7
LRFI 8.7
vgf 8.7
connexin 37 8.7
MAPK6 8.7
MNK1 8.6
5-HT5A 8.6
TRPML3 8.6
NTR2 8.6
NCKX2 8.6
DPP10 8.5
melastatin 2 8.5
ATP11C 8.5
SNS 8.4
Nav1.7 8.4
Annexin A3 8.4
FZD1 8.4
GPR14 8.4
Pannexin 1 8.4
Cav2.2 8.3
Ubiquitin C-terminal hydrolase 8.3
HCN3 8.3
IDO2 8.3
HLA-DQB1*03 8.3
EBI2 8.3
IL-18BP 8.3
KChIP1 8.2
TREK-2 8.2
GlyT1 8.2
Suppressor of cytokine signaling 1 8.2
Kir3.2 8.2
CAV2 8.2
GABA-B receptor 8.1
TWIK-1 8.1
P2Y13 8.1
LPCAT1 8.1
GlyT2 8.1
HCN2 8.1
TASK1 8.1
TREK1 8.0
interleukin-1 receptor-associated kinase 1 8.0
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Disease
HIV neuropathy 10.9
IMD1 10.3
postherpetic neuralgia 9.7
Frey 9.4
phantom limb pain 8.8
mononeuropathy 8.7
regional pain syndrome 8.5
diabetic neuropathy 8.4
trigeminal neuralgia 8.3
nerve lesion 8.2
chronic pain 8.2
Complex regional pain syndrome 7.6
Brown-Sequard syndrome 7.6
psychogenic pain 7.6
plexopathy 7.5
neuroma 7.3
causalgia 7.2
phantom limb 7.2
Burning mouth syndrome 7.2
myelomalacia 7.1
idiopathic disorder 7.1
Diabetic peripheral neuropathy 7.0
peripheral neuropathy 6.9
Fahr's disease 6.9
neuropathy 6.9
Pancoast 6.9
psychological impairment 6.7
radiculopathy 6.3
polyneuropathy 6.2
brachial plexopathy 6.1
disinhibition 6.0
herpes zoster 6.0
neck cancer 5.8
physical dependence 5.8
SCS 5.6
nerve root compression 5.6
monoarthritis 5.5
acute chest syndrome 5.3
PMT 5.2
MLS 5.2
sensory neuropathy 5.2
neuritis 5.1
tension headache 5.0
NPS 5.0
carpal tunnel syndrome 4.8
sleep disturbances 4.8
syringomyelia 4.7
Guillain-Barre syndrome 4.7
leg ulcers 4.6
fibromyalgia 4.6
PTP 4.5
DMS 4.5
spinal cord compression 4.5
bone cancer 4.4
Cannabis 4.4
Menkes 4.4
Roth 4.4
SMD 4.4
tranquilizers 4.4
cold 4.3
HOS 4.3
reflex sympathetic dystrophy 4.3
THC 4.3
neurological disease 4.3
intermittent claudication 4.3
FUS 4.3
sensory disturbance 4.2
GAD 4.2
metachromatic leukodystrophy 4.1
Blocking 4.1
anhedonia 4.1
multiple sclerosis 4.0
lysosomal storage disease 3.9
chronic disease 3.9
pleurisy 3.8
SAD 3.8
genital herpes 3.7
chordoma 3.7
emotional distress 3.7
leprosy 3.7
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Symptom
Neuropathic pain 14.5
Peripheral neuropathic pain 11.5
Chronic chest pain 11.1
Sympathetically maintained pain 11.1
Mechanical pain 10.4
Somatic pain 10.1
Procedural pain 9.9
Other pain 9.8
neurological pain 9.5
nerve pain 8.7
Signs and Symptoms 8.3
Inflammatory pain 8.2
Motor dysfunction 8.1
dysesthesia 8.0
cancer pain 7.8
orofacial pain 7.7
No pain 7.7
Visceral pain 7.6
stump pain 7.6
acute pain 7.3
Severe pain 7.1
tingling 7.1
Deafferentation 7.1
hyperesthesia 7.0
peri-menopausal 7.0
pain 6.9
Chronic pelvic pain 6.8
breakthrough pain 6.7
neuralgia 6.5
dental pain 6.2
paresthesia 6.0
Involuntary Movement 5.8
numbness 5.7
analgesia 5.5
limb pain 5.1
forgetfulness 5.1
bone pain 4.8
sciatica 4.8
facial pain 4.8
despair 4.8
dizziness 4.7
muscle cramps 4.6
sleepiness 4.5
leg pain 4.5
low back pain 4.2
fasciculation 4.1
Sedation 4.1
shoulder pain 4.0
insomnia 3.9
back pain 3.9
anosmia 3.9
spasticity 3.8
incoordination 3.7
neck pain 3.5
skin irritation 3.4
polydipsia 3.3
discomfort 3.2
Wind 3.1
asthenia 3.1
discomfort 3.0
nausea and vomiting 2.8
headache 2.8
constipation 2.7
vertigo 2.7
arthralgia 2.6
tremor 2.6
spasm 2.6
nausea 2.5
ataxia 2.5
pelvic pain 2.5
functional recovery 2.3
acute stress 2.3
distraction 2.3
hunger 2.0
myalgia 1.8
weakness 1.6
hypercapnia 1.5
dystonia 1.4
anesthesia 1.3
stigma 0.8
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Drug
Coix seed 10.4
Naropin 10.4
Vicodin 10.2
Nitecapone 10.0
Benfotiamine 9.3
Namenda 9.3
Tapentadol 9.2
Gabapentin 9.0
Ziconotide 9.0
Vatalanib 9.0
SNL 8.9
Pregabalin 8.9
Nabilone 8.8
Parecoxib 8.6
BOTOX 8.0
DMAA 7.6
Ulinastatin 7.6
Duloxetine 7.2
PDGF B-chain 7.0
Salmon calcitonin 7.0
Moclobemide 6.9
BoNT/A 6.3
Nimesulide 6.2
Domperidone 6.1
IL-1ra 6.0
Piracetam 6.0
Zonisamide 5.9
SMP 5.9
Botox 5.8
Diclofenac sodium 5.7
Oxaliplatin 5.6
Emodin 5.6
Donepezil 5.4
9-THC 5.3
Emodin 5.3
Vitamin B12 5.2
Triad 5.0
Amiloride 4.9
Bupivacaine 4.9
PMPA 4.9
Amiloride 4.6
Diphenhydramine 4.4
Clonidine 4.2
Fentanyl 4.1
BH4 3.9
DM1 3.8
Taxol 3.8
Simvastatin 3.8
DMI 3.4
NAG 3.4
Nitric Oxide 3.1
ICI 3.1
IFN-beta 2.9
p75 2.5
Mutagen 1.9
Indomethacin 1.8
EE2 1.5
MAP 1.5
ENT 1.4
Nephron 1.3
IL-2 1.2
caffeine 1.1
Gel 0.6
CSF 0.5
ROS 0.2
IFN-gamma -0.4
Monit -0.6
lysine -1.4
Enzyme
histone-lysine N-methyltransferase 8.5
IOR 7.2
kynurenine aminotransferase 7.0
kynurenine 3-monooxygenase 6.9
kynureninase 6.9
phosphatidylinositol-4,5-bisphosphate 3-kinase 6.8
lysophosphatidylcholine acyltransferase 6.4
rhodopsin kinase 5.9
CPN 5.7
botulinum neurotoxin 5.6
SCS 5.5
SMP 5.0
indoleamine 2,3-dioxygenase 5.0
SST 4.9
TACE 4.8
tryptophan 2,3-dioxygenase 4.7
TSA 4.2
Thy1 4.2
CPS 4.2
NADPH-diaphorase 4.1
prostate-specific membrane antigen 3.7
PRE 3.5
glutamate decarboxylase 3.4
PARP 3.3
mitogen-activated protein kinase 3.3
DNA methyltransferase 3.2
luciferase 2.9
AMPK 2.8
aldose reductase 2.8
CaMKII 2.5
protein kinase 2.5
neutrophil elastase 2.5
heme oxygenase 2.4
MEK 2.3
IKK 2.2
MIP 2.2
AMPK 1.9
focal adhesion kinase 1.8
glyceraldehyde-3-phosphate dehydrogenase 1.8
AMP-activated protein kinase 1.8
GSK 1.7
ERK 1.7
protein kinase C 1.7
ATP synthase 1.7
caspase-3 1.7
NOS 1.6
MAP 1.6
caspase-9 1.6
NO synthase 1.5
elastase 1.3
phosphodiesterase 1.3
glutathione reductase 1.2
superoxide dismutase 1.2
NADPH oxidase 1.1
monoamine oxidase 1.1
NADPH oxidase 1.0
renin 0.9
beta-galactosidase 0.6
tyrosine hydroxylase 0.6
reverse transcriptase 0.5
calcineurin 0.4
phospholipase C 0.3
catalase 0.3
adenylate cyclase 0.2
glutathione peroxidase 0.0
glutathione S-transferase -0.0
ACS -0.2
acetylcholinesterase -0.3
proteasome -0.4
peroxidase -0.5
RNA polymerase -0.6
trypsin -0.9
ATPase -1.5
Compound
Butrin 13.5
Ginsenoside Rf 12.9
Isoorientin 8.9
Levorphanol 8.7
Palmitoylethanolamide 8.6
cyclopropanecarboxylic acid 8.4
cyclopropanecarboxylic acid 8.4
Anethole 8.3
Methylcobalamin 8.0
Retigabine 7.5
Botulinum toxin type A 7.4
Rifamycin 7.4
Caryophyllene 7.2
Mexiletine 7.2
IBA 7.2
Ethosuximide 7.1
Tramadol 7.0
Ribose 7.0
IBA 7.0
P 2 6.9
Vincristine 6.9
Lamotrigine 6.9
pentanedioic acid 6.9
Oxcarbazepine 6.8
Zonisamide 6.8
Diosgenin 6.7
Acetyl-L-carnitine 6.7
DPN 6.5
NFA 6.5
Oxycodone 6.5
T13 6.3
Paeoniflorin 6.2
Tempol 6.2
TDT 6.1
ANI 6.0
Lidocaine 5.9
Piroxicam 5.8
Riluzole 5.8
Muscimol 5.8
Puerarin 5.8
1H-imidazole 5.7
Evans Blue 5.7
Venlafaxine 5.6
Procaine 5.6
3-hydroxyanthranilic acid 5.6
Minocycline 5.6
Emodin 5.6
MOP 5.5
Baicalin 5.5
Allergan 5.5
Amantadine 5.5
Amantadine 5.5
Ketoprofen 5.5
Nitro-L-arginine 5.5
Triptolide 5.5
PPADS 5.5
carbamic acid 5.5
Amantadine 5.4
Capsaicin 5.4
Desipramine 5.4
Calcitonin 5.3
Bupropion 5.3
Ferulic acid 5.3
Ferulic acid 5.3
T10 5.2
Memantine 5.2
Methadone 5.1
Heroin 5.1
Amitriptyline 5.1
Amantadine 5.1
IPC 5.1
Gb3 5.1
1,3,4-oxadiazole 5.1
Diphenhydramine 5.1
Luteolin 5.0
DAMGO 5.0
Acetone 5.0
DAPT 5.0
Paclitaxel 5.0
NMDA 5.0
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