UMLS:C0423716 - FACTA Search

Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Target Concepts:

Query: UMLS:C0423716 (Neuropathic pain)
1,417 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

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Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein
Sep	97
Mol	96
TNF	63
cytokine	59
IL-6	55
tumor necrosis factor	37
GABA	36
brain-derived neurotrophic factor	28
opioid receptor	26
IL-10	26
ATP	25
glial fibrillary acidic protein	23
NMDA receptor	21
p38	21
DRG	20
substance P	20
axonal	19
interleukin-6	18
P2X	18
calcium channel	17
TRPV1	17
sodium channel	17
inducible nitric oxide synthase	17
CCL2	15
SNS	13
MAPK	13
chemokine	13
calcitonin	12
P2X4	12
TLR4	11
ERK1	11
p38 mitogen-activated protein kinase	10
ERK	10
nerve growth factor	9
signal transducer and activator of transcription 3	9
CGRP	8
tumor necrosis factor alpha	8
histone	8
STAT3	8
lipopolysaccharide	8
mTOR	8
catenin	8
JNK	8
CCR2	8
TRPA1	8
nitric oxide synthase	8
voltage-gated sodium channel	8
caspase-3	7
KCC2	7
membrane-bound	7
IL-1	7
p65	7
TRPM8	7
p38MAPK	6
neurotrophic factor	6
interleukin-10	6
CB1	6
cannabinoid receptor	6
corticotropin-releasing factor	6
PI3K	6
B12	6
NR2B	6
NR1	6
neuronal nitric oxide synthase	6
COX2	6
superoxide dismutase	6
Nav1.7	5
glutamic acid decarboxylase	5
endoplasmic reticulum	5
P2X3	5
GSH	5
dynorphin	5
CB2	5
Iba1	5
NGF	5
PARP	5
glial cell line-derived neurotrophic factor	5
HCN2	5
ionotropic	5
matrix metalloproteinase	5

Disease
chronic pain	263
neuropathy	120
cancer	100
diabetes	93
cold	83
Frey	78
depression	69
peripheral neuropathy	58
postherpetic neuralgia	56
diabetic neuropathy	55
trigeminal neuralgia	37
multiple sclerosis	31
polyneuropathy	26
stroke	19
regional pain syndrome	17
HIV	17
tumor	16
nerve lesion	16
herpes zoster	14
mononeuropathy	14
disinhibition	13
chronic disease	12
phantom limb pain	11
ischemia	11
neuroma	11
epilepsy	10
AIDS	10
radiculopathy	9
addiction	8
neurological disease	8
migraine	8
autoimmune disease	8
Blocking	7
sleep disturbances	7
encephalomyelitis	7
leprosy	6
carpal tunnel syndrome	6
osteoarthritis	6
hypertension	6
Alzheimer's disease	5
confusion	5
fibromyalgia	5
cognitive impairment	5
GSH	5
breast cancer	5
Complex regional pain syndrome	4
Parkinson's disease	4
hyperglycemia	4
psychological distress	4
West	4
arthritis	4
memory impairment	4
immunodeficiency	4
physical dependence	4
Fabry	3
sickle cell disease	3
head and neck cancer	3
pruritus	3
obesity	3
spinal cord compression	3
myelopathy	3
sensory neuropathy	3
emotional distress	3
asthma	3
hyperlipidemia	3
chronic obstructive pulmonary disease	3
metastases	3
sleep disorders	3
rheumatoid arthritis	3
alcoholism	3
neuritis	3
substance abuse	3
leg ulcers	3
type 1 diabetes	3
Cannabis	3
type 2 diabetes	3
pertussis	2
anhedonia	2
NAME	2
immaturity	2

Symptom
Neuropathic pain	1417
pain	1349
analgesia	56
cancer pain	30
acute pain	27
headache	17
paresthesia	14
sleepiness	13
numbness	12
anesthesia	12
dizziness	11
dysesthesia	11
discomfort	10
orofacial pain	9
back pain	8
tingling	8
discomfort	8
low back pain	8
neuralgia	7
insomnia	7
nausea	6
weakness	5
tremor	5
bone pain	4
Peripheral neuropathic pain	4
ataxia	4
dental pain	4
seizures	4
spasticity	4
constipation	3
hyperesthesia	3
nausea and vomiting	3
functional recovery	3
facial pain	3
diarrhea	2
vomiting	2
neck pain	2
arthralgia	2
collapse	2
breakthrough pain	2
sciatica	2
distraction	2
despair	2
spasm	2
fatigue	2
leg pain	2
Signs and Symptoms	2
nerve pain	2
shoulder pain	2
vertigo	2
Mechanical pain	2
Chronic pelvic pain	1
peri-menopausal	1
incoordination	1
acute stress	1
Chronic chest pain	1
skin irritation	1
stump pain	1
Procedural pain	1
neurological pain	1
Involuntary Movement	1
dystonia	1
overweight	1
abdominal pain	1
asthenia	1
muscle cramps	1
pelvic pain	1
Sympathetically maintained pain	1
limb pain	1
myalgia	1
Other pain	1
hunger	1
stigma	1
Deafferentation	1
anorexia	1
Severe pain	1
Motor dysfunction	1
anosmia	1
No pain	1
chest pain	1

Enzyme
mitogen-activated protein kinase	42
protein kinase	20
ERK	14
luciferase	13
protein kinase C	7
focal adhesion kinase	7
superoxide dismutase	6
PARP	6
caspase-3	5
MEK	4
botulinum neurotoxin	4
ACS	3
NADPH-diaphorase	3
renin	3
catalase	3
peroxidase	2
NO synthase	2
AMPK	2
SCS	2
AMPK	2
indoleamine 2,3-dioxygenase	2
DNA methyltransferase	2
AMP-activated protein kinase	2
reverse transcriptase	2
phosphodiesterase	2
kynurenine aminotransferase	1
NADPH oxidase	1
RNA polymerase	1
NOS	1
MIP	1
heme oxygenase	1
IKK	1
neutrophil elastase	1
ATPase	1
monoamine oxidase	1
Thy1	1
calcineurin	1
CPS	1
tyrosine hydroxylase	1
glutathione peroxidase	1
aldose reductase	1
phosphatidylinositol-4,5-bisphosphate 3-kinase	1
rhodopsin kinase	1
phospholipase C	1
CaMKII	1
trypsin	1
SST	1
SMP	1
IOR	1
acetylcholinesterase	1
glutathione reductase	1
beta-galactosidase	1
adenylate cyclase	1
glutamate decarboxylase	1
lysophosphatidylcholine acyltransferase	1
GSK	1
prostate-specific membrane antigen	1
glutathione S-transferase	1
PRE	1
TACE	1
CPN	1
glyceraldehyde-3-phosphate dehydrogenase	1
kynurenine 3-monooxygenase	1
tryptophan 2,3-dioxygenase	1
kynureninase	1
ATP synthase	1
elastase	1
NADPH oxidase	1
proteasome	1
histone-lysine N-methyltransferase	1
MAP	1
caspase-9	1
TSA	1