Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0423716 (Neuropathic pain)
 1,417 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 97
Mol 96
TNF 63
cytokine 59
IL-6 55
tumor necrosis factor 37
GABA 36
brain-derived neurotrophic factor 28
opioid receptor 26
IL-10 26
ATP 25
glial fibrillary acidic protein 23
NMDA receptor 21
p38 21
substance P 20
DRG 20
axonal 19
P2X 18
interleukin-6 18
inducible nitric oxide synthase 17
calcium channel 17
sodium channel 17
TRPV1 17
CCL2 15
MAPK 13
SNS 13
chemokine 13
calcitonin 12
P2X4 12
ERK1 11
TLR4 11
p38 mitogen-activated protein kinase 10
ERK 10
signal transducer and activator of transcription 3 9
nerve growth factor 9
mTOR 8
nitric oxide synthase 8
CGRP 8
voltage-gated sodium channel 8
CCR2 8
more...
Disease
chronic pain 263
neuropathy 120
cancer 100
diabetes 93
cold 83
Frey 78
depression 69
peripheral neuropathy 58
postherpetic neuralgia 56
diabetic neuropathy 55
trigeminal neuralgia 37
multiple sclerosis 31
polyneuropathy 26
stroke 19
HIV 17
regional pain syndrome 17
tumor 16
nerve lesion 16
mononeuropathy 14
herpes zoster 14
disinhibition 13
chronic disease 12
neuroma 11
phantom limb pain 11
ischemia 11
epilepsy 10
AIDS 10
radiculopathy 9
migraine 8
neurological disease 8
addiction 8
autoimmune disease 8
encephalomyelitis 7
sleep disturbances 7
Blocking 7
osteoarthritis 6
leprosy 6
carpal tunnel syndrome 6
hypertension 6
cognitive impairment 5
more...
Symptom
Neuropathic pain 1417
pain 1349
analgesia 56
cancer pain 30
acute pain 27
headache 17
paresthesia 14
sleepiness 13
anesthesia 12
numbness 12
dysesthesia 11
dizziness 11
discomfort 10
orofacial pain 9
tingling 8
discomfort 8
back pain 8
low back pain 8
neuralgia 7
insomnia 7
nausea 6
tremor 5
weakness 5
spasticity 4
seizures 4
ataxia 4
Peripheral neuropathic pain 4
dental pain 4
bone pain 4
constipation 3
hyperesthesia 3
nausea and vomiting 3
functional recovery 3
facial pain 3
Mechanical pain 2
vomiting 2
arthralgia 2
diarrhea 2
collapse 2
neck pain 2
more...
Drug
Gabapentin 20
Pregabalin 9
SNL 4
IL-1ra 4
Tapentadol 3
9-THC 3
IL-2 3
BoNT/A 3
Amiloride 2
caffeine 2
MAP 2
Ziconotide 2
CSF 2
Vitamin B12 2
Taxol 2
Duloxetine 2
Amiloride 2
BOTOX 2
ICI 2
Oxaliplatin 2
Domperidone 2
Nephron 2
Clonidine 2
Vatalanib 1
lysine 1
Nitric Oxide 1
Simvastatin 1
IFN-beta 1
Piracetam 1
DMAA 1
SMP 1
PMPA 1
NAG 1
Coix seed 1
Benfotiamine 1
DM1 1
Nitecapone 1
PDGF B-chain 1
Moclobemide 1
Gel 1
more...
Enzyme
mitogen-activated protein kinase 42
protein kinase 20
ERK 14
luciferase 13
protein kinase C 7
focal adhesion kinase 7
superoxide dismutase 6
PARP 6
caspase-3 5
botulinum neurotoxin 4
MEK 4
ACS 3
renin 3
NADPH-diaphorase 3
catalase 3
peroxidase 2
reverse transcriptase 2
AMPK 2
NO synthase 2
AMP-activated protein kinase 2
AMPK 2
indoleamine 2,3-dioxygenase 2
DNA methyltransferase 2
SCS 2
phosphodiesterase 2
glyceraldehyde-3-phosphate dehydrogenase 1
NOS 1
kynurenine 3-monooxygenase 1
IKK 1
monoamine oxidase 1
Thy1 1
calcineurin 1
ATPase 1
CPS 1
tyrosine hydroxylase 1
glutathione peroxidase 1
phospholipase C 1
trypsin 1
SST 1
SMP 1
more...
Compound
Dec 92
Clin 65
TNF 63
calcium 61
sodium 52
GABA 36
GABA 36
glutamate 34
ATP 25
noradrenaline 25
NMDA 22
oxygen 22
potassium 18
nitric oxide 17
acetone 17
DNA 16
5-HT 12
water 9
Morphine 7
arginine 7
gamma-aminobutyric acid 7
Neuronal 6
Neurotol 6
Lidocaine 6
glucose 6
Capsaicin 5
IBA 5
Gly 5
PGE2 5
IBA 5
AMPA 5
Vincristine 5
GSH 5
Sodium 5
GSH 5
Lamotrigine 4
ADP 4
T10 4
tryptophan 4
hydrogen 4
more...