Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0409974 (lupus)
22,386 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 1297
cytokine 658
She 574
prothrombin 546
glycoprotein 527
thromboplastin 514
CD4 478
SSA 368
IFN 354
Mol 353
interferon 345
IgA 313
lymphoid 300
protein C 296
IL-6 279
beta2-glycoprotein I 274
collagen 264
TNF 258
protein S 255
histone 248
Fas 242
SSB 233
CD8 229
ANA 225
IL-10 216
autoantigen 214
RNP 211
HLA 201
ACR 198
rheumatoid factor 177
SS-A 176
thrombin 174
dilute 166
tumor necrosis factor 151
thymus 149
IFN-gamma 144
C-reactive protein 142
TLR7 141
factor V Leiden 140
IL-4 137
IL-2 132
factor VIII 130
TNF-alpha 130
BAFF 124
MHC 123
TLR9 122
GPI 120
MRI 119
fibrinogen 117
SS-B 116
antithrombin 115
antithrombin III 114
lipopolysaccharide 113
IL-17 113
insulin 108
TCR 103
factor V 100
IgG3 98
type I interferon 96
albumin 95
APS 94
CD20 87
ribonucleoprotein 85
major histocompatibility complex 84
CD25 84
LPS 82
prolactin 81
serum albumin 81
chemokine 81
CD40 79
mucin 78
CD40L 70
ankylosing spondylitis 70
hemoglobin 69
von Willebrand factor 69
MHC class II 69
Pol 69
CD28 68
annexin V 67
myeloperoxidase 66
more...
Disease
lupus 22386
systemic lupus erythematosus 20554
lupus 14988
Lupus 6888
autoimmune disease 1963
antiphospholipid syndrome 1672
lupus nephritis 1638
rheumatoid arthritis 1256
SLE 1248
glomerulonephritis 999
vasculitis 903
arthritis 872
renal disease 869
proteinuria 846
thrombocytopenia 811
nephritis 726
cancer 601
hypertension 535
rash 474
diabetes 387
atherosclerosis 338
scleroderma 329
psoriasis 324
dermatomyositis 318
PSS 313
multiple sclerosis 308
tuberculosis 300
stroke 296
renal failure 273
abortion 262
photosensitivity 257
nephrotic syndrome 253
connective tissue disease 250
heart block 247
skin disease 243
anemia 237
tumor 230
lymphadenopathy 226
preeclampsia 218
dermatitis 213
lymphoma 205
deep vein thrombosis 202
lichen planus 197
pneumonia 192
depression 191
hemolytic anemia 184
HIV 178
panniculitis 175
hepatitis 162
sarcoidosis 159
pulmonary hypertension 158
mixed connective tissue disease 157
systemic disease 157
cardiovascular disease 153
infectious diseases 150
plaque 150
immunodeficiency 150
syphilis 138
myocardial infarction 137
Raynaud's phenomenon 137
Crohn's disease 135
leukopenia 133
psychosis 132
sepsis 131
membranous nephropathy 130
graft-versus-host disease 128
polymyositis 128
pemphigus 125
pericarditis 125
pulmonary embolism 122
sepsis 119
virus infection 117
vascular disease 117
myocarditis 116
thrombocytopenic purpura 111
Infection 108
purpura 108
Sjogren's syndrome 108
atopic dermatitis 107
ischemia 107
more...
Symptom
erythema 248
seizures 215
pain 213
arthralgia 200
headache 185
fatigue 163
abdominal pain 151
livedo 148
splenomegaly 140
dyspnea 103
weakness 94
diarrhea 91
vomiting 84
chorea 79
myalgia 71
nausea 70
chest pain 51
Ill 45
cough 40
shortness of breath 31
hemoptysis 31
angina 30
respiratory distress 29
collapse 28
hepatosplenomegaly 26
anesthesia 21
acute abdominal pain 21
hepatomegaly 19
asthenia 19
anorexia 19
acute abdomen 17
numbness 17
regurgitation 17
fever of unknown origin 17
dry eye 17
dizziness 16
vertigo 15
chills 15
exertional dyspnea 14
blurred vision 14
Flare 14
discomfort 14
insomnia 14
ataxia 14
dysarthria 13
sleepiness 13
pleuritic chest pain 13
lethargy 13
catatonia 13
cerebellar ataxia 12
discomfort 12
nausea and vomiting 12
overweight 12
paresthesia 11
back pain 11
memory loss 11
dysuria 11
epigastric pain 11
hemiplegia 11
paresis 10
syncope 10
paraparesis 9
thinning 9
flushing 9
skin damage 9
cachexia 9
periorbital edema 8
agitation 8
pallor 7
spasm 7
exhaustion 7
dystonia 7
tense 7
oliguria 7
tonic-clonic seizure 7
hip pain 6
hoarseness 6
Gastrointestinal symptoms 6
tachypnea 6
tinnitus 6
more...
Drug
Dermatol 1260
IFN-gamma 141
IL-2 132
Rituximab 73
CSF 61
CTX 49
Nephron 43
Cardiovasc 34
Dial 33
Belimumab 27
Infliximab 26
Infliximab 26
Nephron 25
Prednisolone 25
BLyS 24
lysine 24
Kaolin 21
Prednisone 20
Estrogens 19
Methylprednisolone 16
ROC 16
Tacrolimus 14
Gel 13
Isoniazid 13
ROS 12
G-CSF 12
p75 11
DNase I 11
EE2 10
MAP 10
Adalimumab 9
Silica 9
ENT 9
Vitamin B12 8
Abatacept 8
Asthma 8
ampicillin 8
Bortezomib 8
Alliance 8
Retinoic acid 7
vitamin E 7
Mycophenolic acid 7
Monit 7
IFN-beta 7
Dakar 6
Leaf 6
ABC 6
Fluorescein 6
BLM 6
THF 6
Pimecrolimus 6
Imiquimod 6
Epratuzumab 6
Bifidobacterium 6
Vitamin K 6
Fluorescein 6
caffeine 5
Asn 5
ascorbate 5
CTX 5
niacin 5
Tocilizumab 5
LMWH 5
CAM 5
Captopril 5
CTX 5
Lovastatin 4
Plaquenil 4
PCB 4
Sulphasalazine 4
Orphan 4
Plaquenil 4
TAT 4
nitroglycerin 4
NAG 4
Antithrombin III 3
PFA 3
EPI 3
MDS 3
CaCl2 3
more...
Enzyme
thromboplastin 544
APC 406
thrombin 168
peroxidase 99
mitogen-activated protein kinase 79
ERK 64
calcineurin 57
focal adhesion kinase 56
tissue plasminogen activator 49
DNase 36
methylenetetrahydrofolate reductase 31
methylenetetrahydrofolate reductase 31
catalase 30
alkaline phosphatase 27
RNase 27
superoxide dismutase 26
protein kinase 26
RNA polymerase 25
proteasome 25
creatine kinase 24
RNase 24
ACE 22
trypsin 21
DNA methyltransferase 21
alanine aminotransferase 21
protein kinase C 20
caspase-3 18
reverse transcriptase 18
renin 17
caspase-1 17
aspartate aminotransferase 17
CDR 16
thyroid peroxidase 16
NADPH oxidase 16
NADPH oxidase 16
urokinase-type plasminogen activator 15
glutathione peroxidase 14
luciferase 14
lysozyme 14
lactate dehydrogenase 14
plasmin 13
ATPase 13
neuraminidase 12
granzyme B 11
elastase 11
GP-I 11
MEK 10
kallikrein 10
collagenase 10
endonuclease 10
paraoxonase 10
ACS 10
paraoxonase 9
C3 convertase 9
DNA polymerase 8
AST 8
transglutaminase 8
Thy1 7
lipase 7
ornithine decarboxylase 7
transcriptase 7
phosphodiesterase 7
MAP 6
MIP 6
N-acetyltransferase 6
beta-galactosidase 6
glutathione S-transferase 6
phospholipase A2 6
glyceraldehyde-3-phosphate dehydrogenase 6
GSK 6
MMP 6
NO synthase 6
factor D 6
TSP-1 5
CAD 5
pepsin 5
enolase 5
ancrod 5
cathepsin G 5
CAD 5
more...
Compound
DNA 2315
Clin 2254
Dec 1425
creatinine 322
TNF 258
ANA 226
ANA 226
calcium 176
oxygen 131
APS 94
arginine 94
water 91
His 88
Hydroxychloroquine 86
phosphate 81
Cardiol 78
tyrosine 70
glucose 70
vitamin D 68
acetate 68
urea 65
homocysteine 65
ANCA 62
nitrogen 60
sulfate 57
BCR 56
sodium 55
nitric oxide 52
DBA 51
DBA 51
DBA 51
serine 50
CTX 49
prostacyclin 48
Estrogen 45
Mycophenolate mofetil 45
ATP 41
Estrogen 37
salt 35
Pristane 34
Hydralazine 33
leucine 33
Dial 33
iron 33
mercury 31
lysine 31
Warfarin 29
hydrogen 29
Neo 29
Heparin 28
zinc 27
potassium 27
SDS 27
Asp 26
INH 26
Procainamide 25
Prednisolone 25
hydroxylamine 24
hydroxylamine 24
ADP 24
tryptophan 23
ASA 22
PEG 22
tryptophan 21
tryptophan 21
NKT 21
threonine 21
tryptophan 21
methionine 20
Cyclosporine 20
Prednisone 20
Optimal 20
Azathioprine 20
FK506 19
ADP 18
Chloroquine 18
Chloroquine 18
ADP 18
CCP 18
iodine 18
more...