Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0409974 (
lupus
)
22,386
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
1297
cytokine
658
She
574
prothrombin
546
glycoprotein
527
thromboplastin
514
CD4
478
SSA
368
IFN
354
Mol
353
interferon
345
IgA
313
lymphoid
300
protein C
296
IL-6
279
beta2-glycoprotein I
274
collagen
264
TNF
258
protein S
255
histone
248
Fas
242
SSB
233
CD8
229
ANA
225
IL-10
216
autoantigen
214
RNP
211
HLA
201
ACR
198
rheumatoid factor
177
SS-A
176
thrombin
174
dilute
166
tumor necrosis factor
151
thymus
149
IFN-gamma
144
C-reactive protein
142
TLR7
141
factor V Leiden
140
IL-4
137
IL-2
132
factor VIII
130
TNF-alpha
130
BAFF
124
MHC
123
TLR9
122
GPI
120
MRI
119
fibrinogen
117
SS-B
116
antithrombin
115
antithrombin III
114
lipopolysaccharide
113
IL-17
113
insulin
108
TCR
103
factor V
100
IgG3
98
type I interferon
96
albumin
95
APS
94
CD20
87
ribonucleoprotein
85
major histocompatibility complex
84
CD25
84
LPS
82
prolactin
81
serum albumin
81
chemokine
81
CD40
79
mucin
78
CD40L
70
ankylosing spondylitis
70
hemoglobin
69
von Willebrand factor
69
MHC class II
69
Pol
69
CD28
68
annexin V
67
myeloperoxidase
66
more...
Disease
lupus
22386
systemic lupus erythematosus
20554
lupus
14988
Lupus
6888
autoimmune disease
1963
antiphospholipid syndrome
1672
lupus nephritis
1638
rheumatoid arthritis
1256
SLE
1248
glomerulonephritis
999
vasculitis
903
arthritis
872
renal disease
869
proteinuria
846
thrombocytopenia
811
nephritis
726
cancer
601
hypertension
535
rash
474
diabetes
387
atherosclerosis
338
scleroderma
329
psoriasis
324
dermatomyositis
318
PSS
313
multiple sclerosis
308
tuberculosis
300
stroke
296
renal failure
273
abortion
262
photosensitivity
257
nephrotic syndrome
253
connective tissue disease
250
heart block
247
skin disease
243
anemia
237
tumor
230
lymphadenopathy
226
preeclampsia
218
dermatitis
213
lymphoma
205
deep vein thrombosis
202
lichen planus
197
pneumonia
192
depression
191
hemolytic anemia
184
HIV
178
panniculitis
175
hepatitis
162
sarcoidosis
159
pulmonary hypertension
158
mixed connective tissue disease
157
systemic disease
157
cardiovascular disease
153
infectious diseases
150
plaque
150
immunodeficiency
150
syphilis
138
myocardial infarction
137
Raynaud's phenomenon
137
Crohn's disease
135
leukopenia
133
psychosis
132
sepsis
131
membranous nephropathy
130
graft-versus-host disease
128
polymyositis
128
pemphigus
125
pericarditis
125
pulmonary embolism
122
sepsis
119
virus infection
117
vascular disease
117
myocarditis
116
thrombocytopenic purpura
111
Infection
108
purpura
108
Sjogren's syndrome
108
atopic dermatitis
107
ischemia
107
more...
Symptom
erythema
248
seizures
215
pain
213
arthralgia
200
headache
185
fatigue
163
abdominal pain
151
livedo
148
splenomegaly
140
dyspnea
103
weakness
94
diarrhea
91
vomiting
84
chorea
79
myalgia
71
nausea
70
chest pain
51
Ill
45
cough
40
shortness of breath
31
hemoptysis
31
angina
30
respiratory distress
29
collapse
28
hepatosplenomegaly
26
anesthesia
21
acute abdominal pain
21
hepatomegaly
19
asthenia
19
anorexia
19
acute abdomen
17
numbness
17
regurgitation
17
fever of unknown origin
17
dry eye
17
dizziness
16
vertigo
15
chills
15
exertional dyspnea
14
blurred vision
14
Flare
14
discomfort
14
insomnia
14
ataxia
14
dysarthria
13
sleepiness
13
pleuritic chest pain
13
lethargy
13
catatonia
13
cerebellar ataxia
12
discomfort
12
nausea and vomiting
12
overweight
12
paresthesia
11
back pain
11
memory loss
11
dysuria
11
epigastric pain
11
hemiplegia
11
paresis
10
syncope
10
paraparesis
9
thinning
9
flushing
9
skin damage
9
cachexia
9
periorbital edema
8
agitation
8
pallor
7
spasm
7
exhaustion
7
dystonia
7
tense
7
oliguria
7
tonic-clonic seizure
7
hip pain
6
hoarseness
6
Gastrointestinal symptoms
6
tachypnea
6
tinnitus
6
more...
Drug
Dermatol
1260
IFN-gamma
141
IL-2
132
Rituximab
73
CSF
61
CTX
49
Nephron
43
Cardiovasc
34
Dial
33
Belimumab
27
Infliximab
26
Infliximab
26
Nephron
25
Prednisolone
25
BLyS
24
lysine
24
Kaolin
21
Prednisone
20
Estrogens
19
Methylprednisolone
16
ROC
16
Tacrolimus
14
Gel
13
Isoniazid
13
ROS
12
G-CSF
12
p75
11
DNase I
11
EE2
10
MAP
10
Adalimumab
9
Silica
9
ENT
9
Vitamin B12
8
Abatacept
8
Asthma
8
ampicillin
8
Bortezomib
8
Alliance
8
Retinoic acid
7
vitamin E
7
Mycophenolic acid
7
Monit
7
IFN-beta
7
Dakar
6
Leaf
6
ABC
6
Fluorescein
6
BLM
6
THF
6
Pimecrolimus
6
Imiquimod
6
Epratuzumab
6
Bifidobacterium
6
Vitamin K
6
Fluorescein
6
caffeine
5
Asn
5
ascorbate
5
CTX
5
niacin
5
Tocilizumab
5
LMWH
5
CAM
5
Captopril
5
CTX
5
Lovastatin
4
Plaquenil
4
PCB
4
Sulphasalazine
4
Orphan
4
Plaquenil
4
TAT
4
nitroglycerin
4
NAG
4
Antithrombin III
3
PFA
3
EPI
3
MDS
3
CaCl2
3
more...
Enzyme
thromboplastin
544
APC
406
thrombin
168
peroxidase
99
mitogen-activated protein kinase
79
ERK
64
calcineurin
57
focal adhesion kinase
56
tissue plasminogen activator
49
DNase
36
methylenetetrahydrofolate reductase
31
methylenetetrahydrofolate reductase
31
catalase
30
alkaline phosphatase
27
RNase
27
superoxide dismutase
26
protein kinase
26
RNA polymerase
25
proteasome
25
creatine kinase
24
RNase
24
ACE
22
trypsin
21
DNA methyltransferase
21
alanine aminotransferase
21
protein kinase C
20
caspase-3
18
reverse transcriptase
18
renin
17
caspase-1
17
aspartate aminotransferase
17
CDR
16
thyroid peroxidase
16
NADPH oxidase
16
NADPH oxidase
16
urokinase-type plasminogen activator
15
glutathione peroxidase
14
luciferase
14
lysozyme
14
lactate dehydrogenase
14
plasmin
13
ATPase
13
neuraminidase
12
granzyme B
11
elastase
11
GP-I
11
MEK
10
kallikrein
10
collagenase
10
endonuclease
10
paraoxonase
10
ACS
10
paraoxonase
9
C3 convertase
9
DNA polymerase
8
AST
8
transglutaminase
8
Thy1
7
lipase
7
ornithine decarboxylase
7
transcriptase
7
phosphodiesterase
7
MAP
6
MIP
6
N-acetyltransferase
6
beta-galactosidase
6
glutathione S-transferase
6
phospholipase A2
6
glyceraldehyde-3-phosphate dehydrogenase
6
GSK
6
MMP
6
NO synthase
6
factor D
6
TSP-1
5
CAD
5
pepsin
5
enolase
5
ancrod
5
cathepsin G
5
CAD
5
more...
Compound
DNA
2315
Clin
2254
Dec
1425
creatinine
322
TNF
258
ANA
226
ANA
226
calcium
176
oxygen
131
APS
94
arginine
94
water
91
His
88
Hydroxychloroquine
86
phosphate
81
Cardiol
78
tyrosine
70
glucose
70
vitamin D
68
acetate
68
urea
65
homocysteine
65
ANCA
62
nitrogen
60
sulfate
57
BCR
56
sodium
55
nitric oxide
52
DBA
51
DBA
51
DBA
51
serine
50
CTX
49
prostacyclin
48
Estrogen
45
Mycophenolate mofetil
45
ATP
41
Estrogen
37
salt
35
Pristane
34
Hydralazine
33
leucine
33
Dial
33
iron
33
mercury
31
lysine
31
Warfarin
29
hydrogen
29
Neo
29
Heparin
28
zinc
27
potassium
27
SDS
27
Asp
26
INH
26
Procainamide
25
Prednisolone
25
hydroxylamine
24
hydroxylamine
24
ADP
24
tryptophan
23
ASA
22
PEG
22
tryptophan
21
tryptophan
21
NKT
21
threonine
21
tryptophan
21
methionine
20
Cyclosporine
20
Prednisone
20
Optimal
20
Azathioprine
20
FK506
19
ADP
18
Chloroquine
18
Chloroquine
18
ADP
18
CCP
18
iodine
18
more...